IMP

Process View

Homo sapiens

18 genes annotated in human

Multi-species View

developmental cell growth

GO:0048588

The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "developmental cell growth"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "developmental cell growth" (in gray)

Name	Description	Probability	Func Analog Organism
JUN	jun proto-oncogene	0.977
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.871
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.844	Mouse
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.795
PRKCZ	protein kinase C, zeta	0.788	Mouse
LRRK2	leucine-rich repeat kinase 2	0.768	Worm
MPRIP	myosin phosphatase Rho interacting protein	0.714
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.654
FLNA	filamin A, alpha	0.584
MAPK8	mitogen-activated protein kinase 8	0.584	Fly
ATF2	activating transcription factor 2	0.580
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.547	Fly
ATF3	activating transcription factor 3	0.523	Fly
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.495	Rat
MAP2K4	mitogen-activated protein kinase kinase 4	0.474	Rat
FN1	fibronectin 1	0.422	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.415	Worm
PTPRC	protein tyrosine phosphatase, receptor type, C	0.368
FGFR1	fibroblast growth factor receptor 1	0.337	Fly
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.305
RB1	retinoblastoma 1	0.280
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.279	Fly
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.262
APC	adenomatous polyposis coli	0.243
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.243
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.210
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.204
VEGFA	vascular endothelial growth factor A	0.197	Mouse
TRIO	triple functional domain (PTPRF interacting)	0.184	Worm Fly
ACTN2	actinin, alpha 2	0.183
GSK3B	glycogen synthase kinase 3 beta	0.180	Mouse
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.175	Fly
NRP1	neuropilin 1	0.153	Zebrafish Mouse Rat
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.151
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.146
FMR1	fragile X mental retardation 1	0.142
FGFR2	fibroblast growth factor receptor 2	0.135	Fly
LRP6	low density lipoprotein receptor-related protein 6	0.133
SORBS1	sorbin and SH3 domain containing 1	0.132
EGFR	epidermal growth factor receptor	0.130
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.120
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.120
NCKAP1	NCK-associated protein 1	0.109
ESR1	estrogen receptor 1	0.107
ENG	endoglin	0.106
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.096
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.093	Mouse
TGFB3	transforming growth factor, beta 3	0.090
DST	dystonin	0.090	Fly
HSPG2	heparan sulfate proteoglycan 2	0.088
ABI2	abl-interactor 2	0.088	Fly
DDIT3	DNA-damage-inducible transcript 3	0.087
ADAM19	ADAM metallopeptidase domain 19	0.082
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.082
SESN2	sestrin 2	0.077
FOSL1	FOS-like antigen 1	0.077	Fly
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.075
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.071
PCDHA4	protocadherin alpha 4	0.071
ITGB4	integrin, beta 4	0.071
VAC14	Vac14 homolog (S. cerevisiae)	0.067
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.067
VCAM1	vascular cell adhesion molecule 1	0.066
MAPK9	mitogen-activated protein kinase 9	0.064	Fly
ARRB1	arrestin, beta 1	0.063
AXIN1	axin 1	0.061
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.061
MKL1	megakaryoblastic leukemia (translocation) 1	0.060
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.060
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.060
NAV1	neuron navigator 1	0.060	Worm
SOS1	son of sevenless homolog 1 (Drosophila)	0.059
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.058	Human
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.058
NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	0.058
EED	embryonic ectoderm development	0.056
GRB10	growth factor receptor-bound protein 10	0.054
APP	amyloid beta (A4) precursor protein	0.054	Mouse
CDK9	cyclin-dependent kinase 9	0.054
PGR	progesterone receptor	0.053
CSNK1E	casein kinase 1, epsilon	0.053
PXN	paxillin	0.053
CLIP1	CAP-GLY domain containing linker protein 1	0.051
GEMIN5	gem (nuclear organelle) associated protein 5	0.051
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.047
IGSF21	immunoglobin superfamily, member 21	0.046
PRKCI	protein kinase C, iota	0.046
UNC119	unc-119 homolog (C. elegans)	0.045
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.045
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.044
ACTN1	actinin, alpha 1	0.044
PTCH1	patched 1	0.044
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.043	Mouse
ITGA6	integrin, alpha 6	0.043
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.042	Mouse Fly
FLNB	filamin B, beta	0.041
DLG4	discs, large homolog 4 (Drosophila)	0.040
MACF1	microtubule-actin crosslinking factor 1	0.040	Fly
PLXND1	plexin D1	0.039
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.039
MAPK14	mitogen-activated protein kinase 14	0.039
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.038
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.037
PRMT1	protein arginine methyltransferase 1	0.036
GAS7	growth arrest-specific 7	0.036
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.036
INSR	insulin receptor	0.036	Fly
CBX8	chromobox homolog 8	0.035
RNF2	ring finger protein 2	0.035
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.033
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.033
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.033
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.033
RANBP2	RAN binding protein 2	0.032
IGF1R	insulin-like growth factor 1 receptor	0.031	Fly
CLASP1	cytoplasmic linker associated protein 1	0.031
BAIAP2	BAI1-associated protein 2	0.031
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.030
MARK3	MAP/microtubule affinity-regulating kinase 3	0.030
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.029
PRKG1	protein kinase, cGMP-dependent, type I	0.029
TOP1	topoisomerase (DNA) I	0.029
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.029	Mouse
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.028
SPTBN1	spectrin, beta, non-erythrocytic 1	0.028
FBXO7	F-box protein 7	0.028
MYOD1	myogenic differentiation 1	0.027
KIF5B	kinesin family member 5B	0.027
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.027
CAND1	cullin-associated and neddylation-dissociated 1	0.027
JUNB	jun B proto-oncogene	0.027
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.026	Fly
MAPT	microtubule-associated protein tau	0.026
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.026
GBP3	guanylate binding protein 3	0.026
MARK4	MAP/microtubule affinity-regulating kinase 4	0.026
FZD1	frizzled homolog 1 (Drosophila)	0.025
MYBBP1A	MYB binding protein (P160) 1a	0.025
CREBBP	CREB binding protein	0.024
NCOA1	nuclear receptor coactivator 1	0.024
ABI1	abl-interactor 1	0.024	Fly
PCGF2	polycomb group ring finger 2	0.023
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.023
WASF1	WAS protein family, member 1	0.023	Fly
ATXN1	ataxin 1	0.023
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.023
SFN	stratifin	0.023
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.023
CAPRIN1	cell cycle associated protein 1	0.023
AGTPBP1	ATP/GTP binding protein 1	0.022
TBX5	T-box 5	0.022
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.022	Fly
APLP2	amyloid beta (A4) precursor-like protein 2	0.022
F11R	F11 receptor	0.022
PFN1	profilin 1	0.022
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.022
SPAG9	sperm associated antigen 9	0.022
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.022
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.021
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.021
STRADA	STE20-related kinase adaptor alpha	0.021
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.021
CDH5	cadherin 5, type 2 (vascular endothelium)	0.021
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.021
RBL1	retinoblastoma-like 1 (p107)	0.021
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.021	Mouse
DCC	deleted in colorectal carcinoma	0.021
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.021
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.020
NCOR2	nuclear receptor corepressor 2	0.020
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.020
MYH9	myosin, heavy chain 9, non-muscle	0.020
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.020
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.019
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.019
ZNF512B	zinc finger protein 512B	0.019
CSK	c-src tyrosine kinase	0.019
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.019
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.019
SORBS2	sorbin and SH3 domain containing 2	0.019
MBIP	MAP3K12 binding inhibitory protein 1	0.019
DMPK	dystrophia myotonica-protein kinase	0.019
USP9X	ubiquitin specific peptidase 9, X-linked	0.019
DISC1	disrupted in schizophrenia 1	0.019
TUBA1A	tubulin, alpha 1a	0.019
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
CTSA	cathepsin A	0.019
PTPRD	protein tyrosine phosphatase, receptor type, D	0.019	Fly
PDIA3	protein disulfide isomerase family A, member 3	0.019
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.018
FGF10	fibroblast growth factor 10	0.018
CPE	carboxypeptidase E	0.018
AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)	0.018
CBX6	chromobox homolog 6	0.018
FGF2	fibroblast growth factor 2 (basic)	0.018	Worm
TGFB2	transforming growth factor, beta 2	0.018
RPL18A	ribosomal protein L18a	0.018
GABARAP	GABA(A) receptor-associated protein	0.017
THBS1	thrombospondin 1	0.017
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.017
RTN4	reticulon 4	0.017
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.017
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.017
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.017
DUSP1	dual specificity phosphatase 1	0.017
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.016
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.016
MAPK10	mitogen-activated protein kinase 10	0.016	Fly
NCOA2	nuclear receptor coactivator 2	0.016
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.016
RALGDS	ral guanine nucleotide dissociation stimulator	0.016
TTR	transthyretin	0.016
CHERP	calcium homeostasis endoplasmic reticulum protein	0.016
FAM190B	family with sequence similarity 190, member B	0.016
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.016
SELPLG	selectin P ligand	0.016
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.016
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.015
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.015
RFWD2	ring finger and WD repeat domain 2	0.015
CUL1	cullin 1	0.015
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.015
IQCB1	IQ motif containing B1	0.015
SOX11	SRY (sex determining region Y)-box 11	0.015
TGFB1	transforming growth factor, beta 1	0.015
NCAN	neurocan	0.015
BCL3	B-cell CLL/lymphoma 3	0.015
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.015
NPTN	neuroplastin	0.015
MYOCD	myocardin	0.015
ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.015
WDYHV1	WDYHV motif containing 1	0.015
BCL2	B-cell CLL/lymphoma 2	0.014
JUP	junction plakoglobin	0.014
LBR	lamin B receptor	0.014
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.014
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.014
RUNX1	runt-related transcription factor 1	0.014
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.014
CNOT6	CCR4-NOT transcription complex, subunit 6	0.014
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.014
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.014
JAM2	junctional adhesion molecule 2	0.014
FGFR3	fibroblast growth factor receptor 3	0.013	Fly
NCOA3	nuclear receptor coactivator 3	0.013
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.013
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.013
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.013
FBXO11	F-box protein 11	0.013
MYOZ1	myozenin 1	0.013
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.013
EP300	E1A binding protein p300	0.013
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.013
UBE3A	ubiquitin protein ligase E3A	0.012
SVIL	supervillin	0.012
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.012
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.012
RIN1	Ras and Rab interactor 1	0.012
LAT	linker for activation of T cells	0.012
YBX1	Y box binding protein 1	0.012
UBXN7	UBX domain protein 7	0.012
GAB2	GRB2-associated binding protein 2	0.012
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
NCBP2	nuclear cap binding protein subunit 2, 20kDa	0.012
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.012
PAX6	paired box 6	0.012
VHL	von Hippel-Lindau tumor suppressor	0.012
TNIK	TRAF2 and NCK interacting kinase	0.012	Worm
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.012
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.012
FHL2	four and a half LIM domains 2	0.012
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.012
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.012
RING1	ring finger protein 1	0.011
APLP1	amyloid beta (A4) precursor-like protein 1	0.011
LMNA	lamin A/C	0.011
LYAR	Ly1 antibody reactive homolog (mouse)	0.011
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.011
DCX	doublecortin	0.011	Mouse
CD44	CD44 molecule (Indian blood group)	0.011
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.011
PTPRS	protein tyrosine phosphatase, receptor type, S	0.011	Fly
RANBP9	RAN binding protein 9	0.011
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.011
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.011
BMPR1A	bone morphogenetic protein receptor, type IA	0.011
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.011	Zebrafish
KIAA1377	KIAA1377	0.011
LRP1	low density lipoprotein receptor-related protein 1	0.011
MYOG	myogenin (myogenic factor 4)	0.011
PPARA	peroxisome proliferator-activated receptor alpha	0.011
JAM3	junctional adhesion molecule 3	0.011
EPS8	epidermal growth factor receptor pathway substrate 8	0.011
CDK13	cyclin-dependent kinase 13	0.011
AGRN	agrin	0.011
CUL3	cullin 3	0.011
PARVA	parvin, alpha	0.011
MAP2K7	mitogen-activated protein kinase kinase 7	0.011	Fly
JUND	jun D proto-oncogene	0.010
CD2AP	CD2-associated protein	0.010
CHD3	chromodomain helicase DNA binding protein 3	0.010
PLD2	phospholipase D2	0.010
SCAF8	SR-related CTD-associated factor 8	0.010
FAM160A2	family with sequence similarity 160, member A2	0.010
MARK2	MAP/microtubule affinity-regulating kinase 2	0.010
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.010
CDYL	chromodomain protein, Y-like	0.010
EPHA2	EPH receptor A2	0.010
SFRP1	secreted frizzled-related protein 1	0.010
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.010