IMP

Process View

Mus musculus

2 genes annotated in mouse

regulation of immune complex clearance by monocytes and macrophages

Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of immune complex clearance by monocytes and macrophages"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of immune complex clearance by monocytes and macrophages" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	1.000
Ccl2	chemokine (C-C motif) ligand 2	0.998
Cd44	CD44 antigen	0.998
Tlr4	toll-like receptor 4	0.997
Mmp9	matrix metallopeptidase 9	0.988
Ccr5	chemokine (C-C motif) receptor 5	0.983	Mouse
Ccl3	chemokine (C-C motif) ligand 3	0.971
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.964
Ifng	interferon gamma	0.945
Tlr2	toll-like receptor 2	0.940
Ccr1	chemokine (C-C motif) receptor 1	0.934	Mouse
Il10	interleukin 10	0.916
Nos2	nitric oxide synthase 2, inducible	0.878
Fcrla	Fc receptor-like A	0.801
Il1r1	interleukin 1 receptor, type I	0.731
Tnf	tumor necrosis factor	0.643
Lyz2	lysozyme 2	0.603
Spp1	secreted phosphoprotein 1	0.587
Lepr	leptin receptor	0.542
Selp	selectin, platelet	0.532
Il6	interleukin 6	0.451
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.424
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.318
Blk	B lymphoid kinase	0.318
Cx3cr1	chemokine (C-X3-C) receptor 1	0.314	Mouse
Prdm1	PR domain containing 1, with ZNF domain	0.305
Cd7	CD7 antigen	0.287
Ciita	class II transactivator	0.275
Myd88	myeloid differentiation primary response gene 88	0.274
Ccr6	chemokine (C-C motif) receptor 6	0.271	Mouse
Itgax	integrin alpha X	0.270
Cxcl2	chemokine (C-X-C motif) ligand 2	0.257
Xcr1	chemokine (C motif) receptor 1	0.256	Mouse
Cd180	CD180 antigen	0.251
Nos3	nitric oxide synthase 3, endothelial cell	0.232
Nos1	nitric oxide synthase 1, neuronal	0.227
Icam1	intercellular adhesion molecule 1	0.227
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.221
Cav1	caveolin 1, caveolae protein	0.218
Il27ra	interleukin 27 receptor, alpha	0.211
Ifngr1	interferon gamma receptor 1	0.197
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.195
Lep	leptin	0.185
Pcdh12	protocadherin 12	0.165
Bex6	brain expressed gene 6	0.163
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.158
Fasl	Fas ligand (TNF superfamily, member 6)	0.151
Icos	inducible T-cell co-stimulator	0.139
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.138
H2-Ob	histocompatibility 2, O region beta locus	0.137
Cxcr3	chemokine (C-X-C motif) receptor 3	0.135	Mouse
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.135
Sh2d2a	SH2 domain protein 2A	0.133
Foxp3	forkhead box P3	0.132
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.132
Ldlr	low density lipoprotein receptor	0.131
Il1b	interleukin 1 beta	0.131
Gzmb	granzyme B	0.121
Itgal	integrin alpha L	0.120
Ccl4	chemokine (C-C motif) ligand 4	0.115
Csf1	colony stimulating factor 1 (macrophage)	0.104
Lta	lymphotoxin A	0.104
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.102
Pdcd1	programmed cell death 1	0.102
Il12rb2	interleukin 12 receptor, beta 2	0.100
Spn	sialophorin	0.099
Ncr1	natural cytotoxicity triggering receptor 1	0.095
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.093
Pparg	peroxisome proliferator activated receptor gamma	0.092
Itk	IL2-inducible T-cell kinase	0.091
Cd2	CD2 antigen	0.090
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.086
Tspo2	translocator protein 2	0.082
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.082
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.078
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.077
Tbx21	T-box 21	0.076
Sell	selectin, lymphocyte	0.074
Cd6	CD6 antigen	0.071
Olfr140	olfactory receptor 140	0.069
Stat3	signal transducer and activator of transcription 3	0.068
C3ar1	complement component 3a receptor 1	0.068
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.067
Ccr8	chemokine (C-C motif) receptor 8	0.067	Mouse
Ccl22	chemokine (C-C motif) ligand 22	0.066
Cxcl13	chemokine (C-X-C motif) ligand 13	0.064
Sit1	suppression inducing transmembrane adaptor 1	0.064
Il2rb	interleukin 2 receptor, beta chain	0.063
Hr	hairless	0.062
Il18r1	interleukin 18 receptor 1	0.062
Efna1	ephrin A1	0.062
Fgf7	fibroblast growth factor 7	0.061
Cd40	CD40 antigen	0.060
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.060
Pou2af1	POU domain, class 2, associating factor 1	0.060
Ccr3	chemokine (C-C motif) receptor 3	0.059	Mouse
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.058
Cd86	CD86 antigen	0.057
Cxcr2	chemokine (C-X-C motif) receptor 2	0.057	Mouse
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.056	Mouse
Il18rap	interleukin 18 receptor accessory protein	0.055
Cd19	CD19 antigen	0.055
Ptgs2	prostaglandin-endoperoxide synthase 2	0.055
Cd3e	CD3 antigen, epsilon polypeptide	0.055
Adora2a	adenosine A2a receptor	0.054
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.054
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.053
Tff1	trefoil factor 1	0.052
Il1rn	interleukin 1 receptor antagonist	0.051
Ptgir	prostaglandin I receptor (IP)	0.051
H2-M9	histocompatibility 2, M region locus 9	0.051
Flt3	FMS-like tyrosine kinase 3	0.050
Slamf6	SLAM family member 6	0.050
Cd3d	CD3 antigen, delta polypeptide	0.050
Gzmk	granzyme K	0.049
Wisp2	WNT1 inducible signaling pathway protein 2	0.048
Slamf1	signaling lymphocytic activation molecule family member 1	0.046
Il4	interleukin 4	0.046
Sele	selectin, endothelial cell	0.046
Cxcr5	chemokine (C-X-C motif) receptor 5	0.045	Mouse
Cd96	CD96 antigen	0.045
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.045
Igj	immunoglobulin joining chain	0.043
Oxt	oxytocin	0.043
Cd5	CD5 antigen	0.042
Cd22	CD22 antigen	0.041
Gna15	guanine nucleotide binding protein, alpha 15	0.041
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.041
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.040
Ccl7	chemokine (C-C motif) ligand 7	0.040
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.039
Ccr7	chemokine (C-C motif) receptor 7	0.039	Mouse
Gzma	granzyme A	0.039
Apoe	apolipoprotein E	0.039
Gpr132	G protein-coupled receptor 132	0.039
Il2ra	interleukin 2 receptor, alpha chain	0.038
Folr2	folate receptor 2 (fetal)	0.038
Clec4e	C-type lectin domain family 4, member e	0.038
Ccl8	chemokine (C-C motif) ligand 8	0.038
Ctsw	cathepsin W	0.038
S1pr4	sphingosine-1-phosphate receptor 4	0.038
Xcl1	chemokine (C motif) ligand 1	0.037
Asprv1	aspartic peptidase, retroviral-like 1	0.037
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.036
Ccl17	chemokine (C-C motif) ligand 17	0.036
Plau	plasminogen activator, urokinase	0.034
Elf4	E74-like factor 4 (ets domain transcription factor)	0.034
Ubd	ubiquitin D	0.034
Batf	basic leucine zipper transcription factor, ATF-like	0.034
Il7r	interleukin 7 receptor	0.034
Uts2r	urotensin 2 receptor	0.034
Havcr2	hepatitis A virus cellular receptor 2	0.033
Gcet2	germinal center expressed transcript 2	0.033
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.033
Pla2g2d	phospholipase A2, group IID	0.033
Cdsn	corneodesmosin	0.033
Pdcd1lg2	programmed cell death 1 ligand 2	0.033
Itgae	integrin alpha E, epithelial-associated	0.032
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.032
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.032
Cd8a	CD8 antigen, alpha chain	0.031
Mmp12	matrix metallopeptidase 12	0.030
LOC100502924	hypothetical protein LOC100502924	0.030
Bdkrb1	bradykinin receptor, beta 1	0.030
Hmox1	heme oxygenase (decycling) 1	0.030
Cd8b1	CD8 antigen, beta chain 1	0.029
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.029
Amac1	acyl-malonyl condensing enzyme 1	0.029
H2-Oa	histocompatibility 2, O region alpha locus	0.028
Itgam	integrin alpha M	0.028
Npy2r	neuropeptide Y receptor Y2	0.028
Fut7	fucosyltransferase 7	0.028
Cd4	CD4 antigen	0.028
Fcrl1	Fc receptor-like 1	0.027
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.027
Il1rl1	interleukin 1 receptor-like 1	0.027
Rhoh	ras homolog gene family, member H	0.027
Il15ra	interleukin 15 receptor, alpha chain	0.027
Fut4	fucosyltransferase 4	0.027
Slfn4	schlafen 4	0.027
Gimap3	GTPase, IMAP family member 3	0.027
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.027
Gimap7	GTPase, IMAP family member 7	0.027
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.026
Il12a	interleukin 12a	0.026
Npy1r	neuropeptide Y receptor Y1	0.026
Mmp8	matrix metallopeptidase 8	0.025
Il1a	interleukin 1 alpha	0.025
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.025
Myo1f	myosin IF	0.024
Prg3	proteoglycan 3	0.024
Krt20	keratin 20	0.023
Irf4	interferon regulatory factor 4	0.023
Fcgr1	Fc receptor, IgG, high affinity I	0.023
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.022
Ly6d	lymphocyte antigen 6 complex, locus D	0.022
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.022
C5ar1	complement component 5a receptor 1	0.022
Il9r	interleukin 9 receptor	0.022
Ltk	leukocyte tyrosine kinase	0.022
Krtap3-1	keratin associated protein 3-1	0.022
Krt86	keratin 86	0.022
Adipoq	adiponectin, C1Q and collagen domain containing	0.022
Adamdec1	ADAM-like, decysin 1	0.022
Smad3	MAD homolog 3 (Drosophila)	0.021
Gpr174	G protein-coupled receptor 174	0.021
Clec2i	C-type lectin domain family 2, member i	0.021
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.021
Gdf9	growth differentiation factor 9	0.021
Tssk1	testis-specific serine kinase 1	0.021
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.020
Hrh2	histamine receptor H2	0.020
Tgfb1	transforming growth factor, beta 1	0.020
Zan	zonadhesin	0.020
Il10ra	interleukin 10 receptor, alpha	0.020
Casq1	calsequestrin 1	0.020
Gypa	glycophorin A	0.020
Itga2	integrin alpha 2	0.020
Mc5r	melanocortin 5 receptor	0.020
Glycam1	glycosylation dependent cell adhesion molecule 1	0.020
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.020
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.020
Fpr1	formyl peptide receptor 1	0.020
Tuba8	tubulin, alpha 8	0.019
Cd244	CD244 natural killer cell receptor 2B4	0.019
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.019
Prg2	proteoglycan 2, bone marrow	0.019
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.018
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.018
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.018
Ifitm6	interferon induced transmembrane protein 6	0.018
Cnga1	cyclic nucleotide gated channel alpha 1	0.018
Gpr33	G protein-coupled receptor 33	0.018
Slfn1	schlafen 1	0.018
Tlr7	toll-like receptor 7	0.018
Art2b	ADP-ribosyltransferase 2b	0.018
Gpr18	G protein-coupled receptor 18	0.018
Star	steroidogenic acute regulatory protein	0.018
Cysltr1	cysteinyl leukotriene receptor 1	0.018
Cd36	CD36 antigen	0.018
Cd209a	CD209a antigen	0.017
Ly9	lymphocyte antigen 9	0.017
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.017
Drd2	dopamine receptor D2	0.017
Retn	resistin	0.017
Rhag	Rhesus blood group-associated A glycoprotein	0.017
Tex19.1	testis expressed gene 19.1	0.017
Ids	iduronate 2-sulfatase	0.017
Olfr71	olfactory receptor 71	0.016
Mc2r	melanocortin 2 receptor	0.016
Vpreb3	pre-B lymphocyte gene 3	0.016
Rgs14	regulator of G-protein signaling 14	0.016
Slfn3	schlafen 3	0.016
Pyhin1	pyrin and HIN domain family, member 1	0.016
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.016
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.016
Zp2	zona pellucida glycoprotein 2	0.016
Cd5l	CD5 antigen-like	0.016
Gzmc	granzyme C	0.016
Cd207	CD207 antigen	0.015
Dnajb13	DnaJ (Hsp40) related, subfamily B, member 13	0.015
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.015
Grap2	GRB2-related adaptor protein 2	0.015
Psp	parotid secretory protein	0.015
H2-T24	histocompatibility 2, T region locus 24	0.015
Mc3r	melanocortin 3 receptor	0.015
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.015
Ngp	neutrophilic granule protein	0.015
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.015
LOC100503923	hypothetical protein LOC100503923	0.015
Scd1	stearoyl-Coenzyme A desaturase 1	0.015
Cxcl10	chemokine (C-X-C motif) ligand 10	0.015
Slamf8	SLAM family member 8	0.014
Irg1	immunoresponsive gene 1	0.014
Reg2	regenerating islet-derived 2	0.014
Mpo	myeloperoxidase	0.014
Dusp1	dual specificity phosphatase 1	0.014
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.014
Rasal1	RAS protein activator like 1 (GAP1 like)	0.014
Cd3g	CD3 antigen, gamma polypeptide	0.014
Chi3l3	chitinase 3-like 3	0.014
AF251705	cDNA sequence AF251705	0.014
Mmp3	matrix metallopeptidase 3	0.014
Adam8	a disintegrin and metallopeptidase domain 8	0.014
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.014
Nfe2	nuclear factor, erythroid derived 2	0.013
Ccr10	chemokine (C-C motif) receptor 10	0.013	Mouse
Tbxas1	thromboxane A synthase 1, platelet	0.013
Slc30a3	solute carrier family 30 (zinc transporter), member 3	0.013
Crisp3	cysteine-rich secretory protein 3	0.013
Hivep3	human immunodeficiency virus type I enhancer binding protein 3	0.013
Elk4	ELK4, member of ETS oncogene family	0.013
Cd209b	CD209b antigen	0.013
Hrh1	histamine receptor H1	0.013
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.013
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.013
Il1r2	interleukin 1 receptor, type II	0.013
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.013
Ccl12	chemokine (C-C motif) ligand 12	0.013
Cd14	CD14 antigen	0.013
Mcpt2	mast cell protease 2	0.013
Tcstv3	2-cell-stage, variable group, member 3	0.013
Foxd4	forkhead box D4	0.012
Rpl39l	ribosomal protein L39-like	0.012
Vcam1	vascular cell adhesion molecule 1	0.012
Fmo3	flavin containing monooxygenase 3	0.012
Ccr9	chemokine (C-C motif) receptor 9	0.012	Mouse
Tlr8	toll-like receptor 8	0.012
Ikzf2	IKAROS family zinc finger 2	0.012
Cd160	CD160 antigen	0.012
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.012
Apln	apelin	0.012
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.012
Cd1d2	CD1d2 antigen	0.012
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.012
Ccr4	chemokine (C-C motif) receptor 4	0.012	Mouse
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.012
Cysltr2	cysteinyl leukotriene receptor 2	0.012
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.012
Il16	interleukin 16	0.012
Niacr1	niacin receptor 1	0.012
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
Cd300ld	CD300 molecule-like family member d	0.012
Tktl1	transketolase-like 1	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.012
Sfpi1	SFFV proviral integration 1	0.012
Sdhb	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.012
Cr2	complement receptor 2	0.011
Oosp1	oocyte secreted protein 1	0.011
Ltf	lactotransferrin	0.011
Hpgds	hematopoietic prostaglandin D synthase	0.011
Cnr2	cannabinoid receptor 2 (macrophage)	0.011
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.011
Mcpt8	mast cell protease 8	0.011
Sct	secretin	0.011
Prf1	perforin 1 (pore forming protein)	0.011
Cela2a	chymotrypsin-like elastase family, member 2A	0.011
Trim10	tripartite motif-containing 10	0.011
Nt5e	5' nucleotidase, ecto	0.011
Clec4d	C-type lectin domain family 4, member d	0.011
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.011
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.011
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.011
Arl10	ADP-ribosylation factor-like 10	0.011
Dapk2	death-associated protein kinase 2	0.011
Dock1	dedicator of cytokinesis 1	0.011
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.011
Cxcl5	chemokine (C-X-C motif) ligand 5	0.011
Cox8c	cytochrome c oxidase, subunit VIIIc	0.011
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.011
Rhd	Rh blood group, D antigen	0.011
Ghrl	ghrelin	0.011
Jak3	Janus kinase 3	0.011
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.011
Ccl1	chemokine (C-C motif) ligand 1	0.011
Rel	reticuloendotheliosis oncogene	0.011
Clec5a	C-type lectin domain family 5, member a	0.011
Gp9	glycoprotein 9 (platelet)	0.011
Matk	megakaryocyte-associated tyrosine kinase	0.011
Mag	myelin-associated glycoprotein	0.010
Gsg1	germ cell-specific gene 1	0.010
Gpr182	G protein-coupled receptor 182	0.010
Cd27	CD27 antigen	0.010
Olfr49	olfactory receptor 49	0.010
Elane	elastase, neutrophil expressed	0.010
Cd69	CD69 antigen	0.010
Magoh	mago-nashi homolog, proliferation-associated (Drosophila)	0.010
Ltb	lymphotoxin B	0.010
Dusp2	dual specificity phosphatase 2	0.010
Elk1	ELK1, member of ETS oncogene family	0.010
Itga4	integrin alpha 4	0.010
Ltb4r1	leukotriene B4 receptor 1	0.010
Faim3	Fas apoptotic inhibitory molecule 3	0.010