Process View
The network for 'regulation of peptidyl serine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.997 | |
| SMAD3 | SMAD family member 3 | 0.988 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.837 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.754 | |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.696 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.695 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.684 | |
| SMAD2 | SMAD family member 2 | 0.676 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.657 | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.602 | |
| VEGFA | vascular endothelial growth factor A | 0.572 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.565 | |
| SH2D4A | SH2 domain containing 4A | 0.522 | |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.502 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.488 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.418 | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.398 | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.363 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.362 | |
| SMAD1 | SMAD family member 1 | 0.348 | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.338 | |
| NCF1 | neutrophil cytosolic factor 1 | 0.333 | |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.326 | |
| EGFR | epidermal growth factor receptor | 0.314 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.302 | |
| NRP1 | neuropilin 1 | 0.287 | |
| BCL2L1 | BCL2-like 1 | 0.283 | |
| TEK | TEK tyrosine kinase, endothelial | 0.270 | |
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.260 | |
| AXL | AXL receptor tyrosine kinase | 0.231 | |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 0.222 | |
| DTNA | dystrobrevin, alpha | 0.220 | |
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.218 | |
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.216 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.210 | |
| PRDX1 | peroxiredoxin 1 | 0.209 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.209 | |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.206 | |
| NOXA1 | NADPH oxidase activator 1 | 0.206 | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.204 | |
| MAPT | microtubule-associated protein tau | 0.204 | |
| FHL1 | four and a half LIM domains 1 | 0.203 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.194 | |
| PRKCZ | protein kinase C, zeta | 0.194 | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.194 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.187 | |
| ANGPT2 | angiopoietin 2 | 0.186 | |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.179 | |
| IL8 | interleukin 8 | 0.177 | |
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.165 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.165 | |
| MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) | 0.160 | |
| SMAD5 | SMAD family member 5 | 0.154 | |
| SMAD7 | SMAD family member 7 | 0.152 | |
| ARRB2 | arrestin, beta 2 | 0.151 | |
| BAK1 | BCL2-antagonist/killer 1 | 0.150 | |
| MAGEA11 | melanoma antigen family A, 11 | 0.147 | |
| YAP1 | Yes-associated protein 1 | 0.146 | |
| ANGPT1 | angiopoietin 1 | 0.144 | |
| BAD | BCL2-associated agonist of cell death | 0.132 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.131 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.130 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.127 | |
| PTPRN | protein tyrosine phosphatase, receptor type, N | 0.125 | |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.124 | |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.117 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.111 | |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.105 | |
| NGF | nerve growth factor (beta polypeptide) | 0.103 | |
| LAT | linker for activation of T cells | 0.102 | |
| IL6R | interleukin 6 receptor | 0.102 | |
| ENG | endoglin | 0.098 | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.094 | |
| CDK11B | cyclin-dependent kinase 11B | 0.093 | |
| SQSTM1 | sequestosome 1 | 0.088 | |
| PRKCA | protein kinase C, alpha | 0.084 | |
| PDGFC | platelet derived growth factor C | 0.081 | |
| MSN | moesin | 0.079 | |
| GHR | growth hormone receptor | 0.079 | |
| TESK1 | testis-specific kinase 1 | 0.078 | |
| BDNF | brain-derived neurotrophic factor | 0.076 | |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.076 | |
| NCF2 | neutrophil cytosolic factor 2 | 0.075 | |
| YY1 | YY1 transcription factor | 0.073 | |
| ARRB1 | arrestin, beta 1 | 0.073 | |
| SMAD4 | SMAD family member 4 | 0.069 | |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.069 | |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.067 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.066 | |
| NTF3 | neurotrophin 3 | 0.065 | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.065 | |
| KSR1 | kinase suppressor of ras 1 | 0.061 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.061 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.061 | |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.060 | |
| CXXC5 | CXXC finger protein 5 | 0.059 | |
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.059 | |
| FBXO7 | F-box protein 7 | 0.059 | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.058 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.058 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Smad3 | MAD homolog 3 (Drosophila) | 0.996 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.996 | |
| Apc | adenomatosis polyposis coli | 0.989 | |
| Pten | phosphatase and tensin homolog | 0.980 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.977 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.974 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.963 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.949 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.924 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.906 | |
| Lepr | leptin receptor | 0.879 | |
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.875 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.875 | |
| Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.847 | |
| Ren1 | renin 1 structural | 0.821 | |
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.821 | |
| Axin1 | axin 1 | 0.818 | |
| Bax | BCL2-associated X protein | 0.788 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.742 | |
| Arrb2 | arrestin, beta 2 | 0.722 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.716 | |
| Sfrp1 | secreted frizzled-related protein 1 | 0.702 | |
| Pax2 | paired box gene 2 | 0.678 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.632 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.631 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.628 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.538 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.530 | |
| Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.523 | |
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.464 | |
| Wt1 | Wilms tumor 1 homolog | 0.426 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.402 | |
| Kdr | kinase insert domain protein receptor | 0.394 | |
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.391 | |
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.378 | |
| Ret | ret proto-oncogene | 0.358 | |
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.353 | |
| Arrb1 | arrestin, beta 1 | 0.350 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.347 | |
| Smad1 | MAD homolog 1 (Drosophila) | 0.332 | |
| Bdnf | brain derived neurotrophic factor | 0.330 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.326 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.325 | |
| Il6st | interleukin 6 signal transducer | 0.323 | |
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.301 | |
| Arhgdia | Rho GDP dissociation inhibitor (GDI) alpha | 0.300 | |
| Braf | Braf transforming gene | 0.289 | |
| Ank1 | ankyrin 1, erythroid | 0.265 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.254 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.243 | |
| Vegfa | vascular endothelial growth factor A | 0.243 | |
| Pgr | progesterone receptor | 0.239 | |
| Erbb2ip | Erbb2 interacting protein | 0.237 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.232 | |
| Il10 | interleukin 10 | 0.228 | |
| Klhl24 | kelch-like 24 (Drosophila) | 0.227 | |
| Stk11 | serine/threonine kinase 11 | 0.225 | |
| Actb | actin, beta | 0.218 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.216 | |
| Pax8 | paired box gene 8 | 0.211 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.203 | |
| Vdr | vitamin D receptor | 0.190 | |
| Rnf111 | ring finger 111 | 0.189 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.187 | |
| Kitl | kit ligand | 0.186 | |
| Drd2 | dopamine receptor D2 | 0.185 | |
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.183 | |
| Wnt6 | wingless-related MMTV integration site 6 | 0.181 | |
| Sfrp2 | secreted frizzled-related protein 2 | 0.176 | |
| Rictor | RPTOR independent companion of MTOR, complex 2 | 0.173 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.172 | |
| Smurf2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.172 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.170 | |
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.165 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.165 | |
| Lhx1 | LIM homeobox protein 1 | 0.161 | |
| Cav1 | caveolin 1, caveolae protein | 0.161 | |
| Foxa2 | forkhead box A2 | 0.159 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.159 | |
| Lrrk2 | leucine-rich repeat kinase 2 | 0.155 | |
| Esr2 | estrogen receptor 2 (beta) | 0.153 | |
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.152 | |
| Prkg1 | protein kinase, cGMP-dependent, type I | 0.150 | |
| Nr2f1 | nuclear receptor subfamily 2, group F, member 1 | 0.150 | |
| Cfl1 | cofilin 1, non-muscle | 0.149 | |
| Cdh5 | cadherin 5 | 0.149 | |
| En1 | engrailed 1 | 0.146 | |
| Grb2 | growth factor receptor bound protein 2 | 0.145 | |
| Bdkrb2 | bradykinin receptor, beta 2 | 0.141 | |
| Il1r1 | interleukin 1 receptor, type I | 0.141 | |
| Irs1 | insulin receptor substrate 1 | 0.138 | |
| Kit | kit oncogene | 0.131 | |
| Spry4 | sprouty homolog 4 (Drosophila) | 0.130 | |
| Smurf1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.130 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.129 | |
| Dvl2 | dishevelled 2, dsh homolog (Drosophila) | 0.124 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.124 | |
| Ghr | growth hormone receptor | 0.123 | |
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.121 | |
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.121 |