The network for 'immune response regulating signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

immune response regulating signaling pathway

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.

Name Description Probability Func Analog Organism
Myd88 myeloid differentiation primary response gene 88 1.000
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.998
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.998
Tlr4 toll-like receptor 4 0.996
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.991
Traf6 TNF receptor-associated factor 6 0.990
Stat3 signal transducer and activator of transcription 3 0.990
Fyn Fyn proto-oncogene 0.990
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.986
Ikzf1 IKAROS family zinc finger 1 0.984
Lyz2 lysozyme 2 0.981
Ptprc protein tyrosine phosphatase, receptor type, C 0.980
Inpp5d inositol polyphosphate-5-phosphatase D 0.979
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.978
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.977
Slamf1 signaling lymphocytic activation molecule family member 1 0.973
Cd22 CD22 antigen 0.973
Vav1 vav 1 oncogene 0.966
Grb2 growth factor receptor bound protein 2 0.959
Cd180 CD180 antigen 0.958
Icos inducible T-cell co-stimulator 0.958
Cd19 CD19 antigen 0.957
Sykb spleen tyrosine kinase 0.956
Bcl3 B-cell leukemia/lymphoma 3 0.954
Pten phosphatase and tensin homolog 0.947
Jak2 Janus kinase 2 0.945
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.931
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.924
Ptk2 PTK2 protein tyrosine kinase 2 0.922
Ifnar1 interferon (alpha and beta) receptor 1 0.920
Il2rb interleukin 2 receptor, beta chain 0.920
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.918
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.915
Igh immunoglobulin heavy chain complex 0.914
Fasl Fas ligand (TNF superfamily, member 6) 0.913
Rxra retinoid X receptor alpha 0.913
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.898
Birc3 baculoviral IAP repeat-containing 3 0.896
Cd4 CD4 antigen 0.889
Axl AXL receptor tyrosine kinase 0.886
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.864
Cr2 complement receptor 2 0.861
Irf7 interferon regulatory factor 7 0.857
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.823
Notch2 Notch gene homolog 2 (Drosophila) 0.822
Rel reticuloendotheliosis oncogene 0.819
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.819
Ticam1 toll-like receptor adaptor molecule 1 0.794
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.787
Blk B lymphoid kinase 0.778
Pyhin1 pyrin and HIN domain family, member 1 0.772
Foxp3 forkhead box P3 0.764
Cbl Casitas B-lineage lymphoma 0.762
Card11 caspase recruitment domain family, member 11 0.761
Unc93b1 unc-93 homolog B1 (C. elegans) 0.758
Ccr6 chemokine (C-C motif) receptor 6 0.756
Stat1 signal transducer and activator of transcription 1 0.755
Gata4 GATA binding protein 4 0.742
Cd44 CD44 antigen 0.730
Prdm1 PR domain containing 1, with ZNF domain 0.727
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.723
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.713
Ccr2 chemokine (C-C motif) receptor 2 0.709
Ncr1 natural cytotoxicity triggering receptor 1 0.708
Slamf6 SLAM family member 6 0.701
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.690
Cdh5 cadherin 5 0.689
Irf1 interferon regulatory factor 1 0.682
Tgfb1 transforming growth factor, beta 1 0.677
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.676
Pxn paxillin 0.670
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.669
Irak3 interleukin-1 receptor-associated kinase 3 0.660
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.647
Lat linker for activation of T cells 0.645
Cd84 CD84 antigen 0.641
BC013712 cDNA sequence BC013712 0.637
Src Rous sarcoma oncogene 0.637
Reg3g regenerating islet-derived 3 gamma 0.635
Il1r1 interleukin 1 receptor, type I 0.633
Itgax integrin alpha X 0.632
Cd247 CD247 antigen 0.629
Gnrh1 gonadotropin releasing hormone 1 0.628
Stat6 signal transducer and activator of transcription 6 0.619
Msr1 macrophage scavenger receptor 1 0.615
Parp14 poly (ADP-ribose) polymerase family, member 14 0.615
Ltbr lymphotoxin B receptor 0.609
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.607
Smad4 MAD homolog 4 (Drosophila) 0.607
Ncf1 neutrophil cytosolic factor 1 0.604
Tnip1 TNFAIP3 interacting protein 1 0.601
Socs1 suppressor of cytokine signaling 1 0.597
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.595
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.594
Prkcd protein kinase C, delta 0.592
Irf9 interferon regulatory factor 9 0.573
Apc adenomatosis polyposis coli 0.567
Il7r interleukin 7 receptor 0.562
Cybb cytochrome b-245, beta polypeptide 0.561
Cd300ld CD300 molecule-like family member d 0.560
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_C27D8.2 Protein C27D8.2 0.024
oga-1 Protein OGA-1 0.019
egl-8 Protein EGL-8 0.018
T28F4.3 Protein T28F4.3 0.017
tlf-1 Protein TLF-1 0.017
itr-1 Protein ITR-1 0.016
pek-1 Protein PEK-1 0.016
C35A5.4 Protein C35A5.4 0.016
CELE_Y69A2AR.8 Protein Y69A2AR.8 0.015
vav-1 Protein VAV-1 0.015
F21A10.2 Protein F21A10.2 0.015
pmk-1 Protein PMK-1 0.015
rab-14 Protein RAB-14 0.015
CELE_Y44A6D.5 Protein Y44A6D.5 0.015
abl-1 Protein ABL-1 0.014
D2013.6 Protein D2013.6 0.014
acs-6 Protein ACS-6 0.014
cgef-1 Protein CGEF-1 0.014
akt-2 Protein AKT-2 0.014
sek-1 Protein SEK-1 0.014
nra-3 Protein NRA-3 0.014
CELE_D1046.3 Protein D1046.3 0.014
C36F7.5 Protein C36F7.5 0.014
C18B12.4 Protein C18B12.4 0.014
K10B3.6 Protein K10B3.6 0.014
C17H11.2 Protein C17H11.2 0.013
CELE_Y57E12AL.6 Protein Y57E12AL.6 0.013
CELE_Y106G6D.3 Protein Y106G6D.3 0.013
egl-27 Protein EGL-27 0.013
Y22D7AL.10 Protein Y22D7AL.10 0.013
CELE_C28D4.8 Protein C28D4.8 0.013
CELE_B0334.5 Protein B0334.5 0.013
ptp-3 Protein PTP-3 0.013
tax-6 Protein TAX-6 0.013
tat-4 Protein TAT-4 0.013
tps-1 Protein TPS-1 0.013
unc-32 Protein UNC-32 0.013
F54D8.6 Protein F54D8.6 0.012
pqn-21 Protein PQN-21 0.012
F46H5.2 Protein F46H5.2 0.012
magi-1 Protein MAGI-1 0.012
ZK622.1 Protein ZK622.1 0.012
K08A2.2 Protein K08A2.2 0.012
unc-43 Protein UNC-43 0.012
K07A3.3 Protein K07A3.3 0.012
T01E8.1 Protein T01E8.1 0.012
sym-4 Protein SYM-4 0.012
T10E9.2 Protein T10E9.2 0.012
F47A4.5 Protein F47A4.5 0.012
M110.7 Protein M110.7 0.012
sax-3 Protein SAX-3 0.012
erp-1 Protein ERP-1 0.012
CELE_F36H12.3 Protein F36H12.3 0.012
gsy-1 Protein GSY-1 0.012
F47B3.6 Protein F47B3.6 0.012
eya-1 Protein EYA-1 0.012
CELE_C06C6.7 Protein C06C6.7 0.012
sec-15 Protein SEC-15 0.012
R151.4 Protein R151.4 0.012
CELE_Y105E8A.27 Protein Y105E8A.27 0.012
flh-2 Protein FLH-2 0.012
snb-1 Protein SNB-1 0.012
mppa-1 Protein MPPA-1 0.012
let-23 Protein LET-23 0.012
sam-10 Protein SAM-10 0.012
E01B7.1 Protein E01B7.1 0.012
CELE_M04G7.2 Protein M04G7.2 0.012
F56C11.6 Protein F56C11.6 0.012
prk-1 Protein PRK-1 0.011
eat-4 Protein EAT-4 0.011
C55C3.4 Protein C55C3.4 0.011
toca-1 Protein TOCA-1 0.011
aak-2 Protein AAK-2 0.011
dnj-14 Protein DNJ-14 0.011
mfb-1 Protein MFB-1 0.011
lntl-1 Protein LNTL-1 0.011
F21F3.3 Protein F21F3.3 0.011
rsy-1 Protein RSY-1 0.011
F42G4.6 Protein F42G4.6 0.011
F21F3.2 Protein F21F3.2 0.011
F33D11.12 Protein F33D11.12 0.011
dlc-6 Protein DLC-6 0.011
let-526 Protein LET-526 0.011
CELE_C08F8.6 Protein C08F8.6 0.011
uso-1 Protein USO-1 0.011
gpb-2 Protein GPB-2 0.011
cam-1 Protein CAM-1 0.011
F14D12.1 Protein F14D12.1 0.011
CELE_Y57G11C.14 Protein Y57G11C.14 0.011
K10B3.5 Protein K10B3.5 0.011
zfp-3 Protein ZFP-3 0.011
CELE_F44G3.7 Protein F44G3.7 0.011
mig-10 Protein MIG-10 0.011
EEED8.15 Protein EEED8.15 0.011
drh-1 Protein DRH-1 0.011
K09C6.7 Protein K09C6.7 0.011
unc-11 Protein UNC-11 0.011
csn-1 Protein CSN-1 0.011
cbp-1 Protein CBP-1 0.011
ctl-3 Protein CTL-3 0.011
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Danio rerio
Name Description Probability Func Analog Organism
tlr3 toll-like receptor 3 0.563
pdcd2 programmed cell death 2 0.508
LOC566708 FL cytokine receptor-like 0.431
ighz immunoglobulin heavy constant zeta 0.290
tlr9 toll-like receptor 9 0.264
LOC100151531 zinc finger protein Gfi-1b-like 0.225
stc1l stanniocalcin 1, like 0.182
aplp2 amyloid beta (A4) precursor-like protein 2 0.112
epas1b endothelial PAS domain protein 1b 0.102
tnfb tumor necrosis factor b (TNF superfamily, member 2) 0.100
epor erythropoietin receptor 0.096
nod1 nucleotide-binding oligomerization domain containing 1 0.088
LOC557072 caspase recruitment domain-containing protein 11-like 0.082
elovl4a elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a 0.075
irak4 interleukin-1 receptor-associated kinase 4 0.072
efna2 ephrin A2 0.072
tlr2 toll-like receptor 2 0.057
cacnb4a calcium channel, voltage-dependent, beta 4a subunit 0.053
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.050
fam20b family with sequence similarity 20, member B (H. sapiens) 0.046
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.045
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.042
sh3gl1b SH3-domain GRB2-like 1b 0.042
LOC100000934 hypothetical protein LOC100000934 0.038
ighm immunoglobulin heavy constant mu and immunoglobulin heavy constant mu 0.035
il22 interleukin 22 0.034
abcg2c ATP-binding cassette, sub-family G (WHITE), member 2c 0.031
angptl2 angiopoietin-like 2 0.030
rel v-rel reticuloendotheliosis viral oncogene homolog 0.028
ptena phosphatase and tensin homolog A 0.028
gclc glutamate-cysteine ligase, catalytic subunit 0.028
fcho2 FCH domain only 2 0.028
ftsj FtsJ homolog 3 (E. coli) 0.027
mib mind bomb 0.026
sp2 sp2 transcription factor 0.026
rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.025
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.024
myd88 myeloid differentiation primary response gene (88) 0.024
ccr6a chemokine (C-C motif) receptor 6a 0.023
spns2 spinster homolog 2 (Drosophila) 0.021
lyz lysozyme 0.019
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.018
gip gastric inhibitory polypeptide 0.018
ef1a elongation factor 1-alpha 0.018
trim3a tripartite motif-containing 3a 0.018
tlr20a toll-like receptor 20a 0.017
smyd3 SET and MYND domain containing 3 0.017
tbx21 T-box 21 0.017
tlr18 toll-like receptor 18 0.017
cdh4 cadherin 4, retinal 0.016
drgx dorsal root ganglia homeobox 0.016
dnmt6 DNA (cytosine-5-)-methyltransferase 6 0.016
gfi1.1 growth factor independent 1.1 0.016
ip6k2 inositol hexaphosphate kinase 2 0.015
tirap toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.015
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.015
dntt deoxynucleotidyltransferase, terminal 0.014
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.014
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.014
tert telomerase reverse transcriptase 0.014
LOC560602 novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6) 0.013
sb:eu1637 sb:eu1637 0.013
zgc:101737 zgc:101737 0.013
insrb insulin receptor b 0.013
LOC100534776 toll-like receptor 7-like 0.013
ticam1 toll-like receptor adaptor molecule 1 0.013
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.012
traf6 TNF receptor-associated factor 6 0.012
cacnb2b calcium channel, voltage-dependent, beta 2b 0.012
baxa bcl2-associated X protein, a 0.012
cntn2 contactin 2 0.012
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.012
flot1 flotillin 1 0.012
fn1 fibronectin 1 0.012
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.012
grna granulin a 0.011
cnih cornichon homolog (Drosophila) 0.011
polb polymerase (DNA directed), beta 0.011
cd247l CD247 antigen like 0.010
mmp9 matrix metalloproteinase 9 0.010
fam53b family with sequence similarity 53, member B 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
PGRP-SA Peptidoglycan recognition protein SA 0.928
Rel Relish 0.712
PGRP-LC Peptidoglycan recognition protein LC 0.598
grass Gram-positive Specific Serine protease 0.579
sno strawberry notch 0.437
modSP modular serine protease 0.431
Toll-6 CG7250 gene product from transcript CG7250-RA 0.404
Spn27A Serpin 27A 0.397
Krn Keren 0.383
Sema-1b CG6446 gene product from transcript CG6446-RA 0.380
SPE Spatzle-Processing Enzyme 0.378
krz kurtz 0.368
p38b CG7393 gene product from transcript CG7393-RA 0.366
Toll-7 CG8595 gene product from transcript CG8595-RA 0.363
Duox Dual oxidase 0.362
AttA Attacin-A 0.335
Rgl Ral guanine nucleotide exchange factor 0.325
babo baboon 0.321
verm vermiform 0.316
rut rutabaga 0.316
pirk poor Imd response upon knock-in 0.312
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.311
CG16718 CG16718 gene product from transcript CG16718-RA 0.294
Pcaf CG4107 gene product from transcript CG4107-RA 0.294
Vang Van Gogh 0.287
baz bazooka 0.263
foxo forkhead box, sub-group O 0.247
Mtk Metchnikowin 0.242
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.232
Rac2 CG8556 gene product from transcript CG8556-RA 0.227
egh egghead 0.226
NFAT NFAT homolog 0.226
POSH Plenty of SH3s 0.222
Ras64B Ras oncogene at 64B 0.221
Irk2 Inwardly rectifying potassium channel 2 0.207
aux auxillin 0.207
Mpk2 CG5475 gene product from transcript CG5475-RB 0.186
plexB plexin B 0.182
Cat Catalase 0.181
grn grain 0.173
Smox Smad on X 0.172
CG10743 CG10743 gene product from transcript CG10743-RB 0.172
Fas3 Fasciclin 3 0.171
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.163
upd2 unpaired 2 0.159
CG5794 CG5794 gene product from transcript CG5794-RB 0.158
crol crooked legs 0.155
pgant3 polypeptide GalNAc transferase 3 0.147
Nrx-IV Neurexin IV 0.146
slmb supernumerary limbs 0.144
CG15917 CG15917 gene product from transcript CG15917-RA 0.144
ari-1 ariadne 0.143
Sp7 Serine protease 7 0.142
slow slowdown 0.138
ird5 immune response deficient 5 0.132
pan pangolin 0.131
msn misshapen 0.130
Dredd Death related ced-3/Nedd2-like protein 0.130
coro CG9446 gene product from transcript CG9446-RC 0.130
Myo31DF Myosin 31DF 0.130
shark Src homology 2, ankyrin repeat, tyrosine kinase 0.128
Myd88 CG2078 gene product from transcript CG2078-RA 0.127
CG18594 CG18594 gene product from transcript CG18594-RA 0.126
p53 CG33336 gene product from transcript CG33336-RB 0.123
l(3)mbn lethal (3) malignant blood neoplasm 0.121
trol terribly reduced optic lobes 0.119
disco disconnected 0.118
CG10650 CG10650 gene product from transcript CG10650-RA 0.117
l(2)k16918 lethal (2) k16918 0.116
PGRP-LF Peptidoglycan recognition protein LF 0.115
Sdc Syndecan 0.115
wun wunen 0.115
CG6116 CG6116 gene product from transcript CG6116-RA 0.112
hebe CG1623 gene product from transcript CG1623-RD 0.112
Mekk1 CG7717 gene product from transcript CG7717-RB 0.111
LIMK1 LIM-kinase1 0.109
plexA plexin A 0.109
Eb1 CG3265 gene product from transcript CG3265-RF 0.108
CG42863 CG42863 gene product from transcript CG42863-RB 0.106
Gadd45 CG11086 gene product from transcript CG11086-RA 0.104
Pk92B Protein kinase at 92B 0.102
dia diaphanous 0.101
Hcf Host cell factor 0.100
Akt1 CG4006 gene product from transcript CG4006-RA 0.099
dco discs overgrown 0.096
ds dachsous 0.095
Spn1 Serine protease inhibitor 1 0.094
pigs pickled eggs 0.094
shn schnurri 0.094
zfh1 Zn finger homeodomain 1 0.093
rt rotated abdomen 0.092
mnb minibrain 0.092
kek5 kekkon5 0.091
chrb charybde 0.090
Mcr Macroglobulin complement-related 0.090
ImpL2 Ecdysone-inducible gene L2 0.089
CG10414 CG10414 gene product from transcript CG10414-RA 0.089
fra frazzled 0.089
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.089
Su(dx) Suppressor of deltex 0.087
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Homo sapiens
Name Description Probability Func Analog Organism
GRB2 growth factor receptor-bound protein 2 1.000
LCK lymphocyte-specific protein tyrosine kinase 1.000
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
TRAF6 TNF receptor-associated factor 6 0.998
EGFR epidermal growth factor receptor 0.998
IRAK1 interleukin-1 receptor-associated kinase 1 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.996
MAPK1 mitogen-activated protein kinase 1 0.994
LAT linker for activation of T cells 0.993
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.979
MYD88 myeloid differentiation primary response gene (88) 0.979
MAPK14 mitogen-activated protein kinase 14 0.977
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.969
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.968
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.964
PTK2 PTK2 protein tyrosine kinase 2 0.948
VAV1 vav 1 guanine nucleotide exchange factor 0.941
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.940
BIRC3 baculoviral IAP repeat containing 3 0.938
BCL2L1 BCL2-like 1 0.936
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.926
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.919
B2M beta-2-microglobulin 0.907
IRAK2 interleukin-1 receptor-associated kinase 2 0.904
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.901
CD80 CD80 molecule 0.880
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.877
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.873
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.813
HLA-B major histocompatibility complex, class I, B 0.807
HLA-C major histocompatibility complex, class I, C 0.807
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.805
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.800
PILRA paired immunoglobin-like type 2 receptor alpha 0.775
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.771
BCL2 B-cell CLL/lymphoma 2 0.764
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.760
FYN FYN oncogene related to SRC, FGR, YES 0.760
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.759
BTK Bruton agammaglobulinemia tyrosine kinase 0.756
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.750
TRAF3 TNF receptor-associated factor 3 0.749
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.745
UBC ubiquitin C 0.742
GAB1 GRB2-associated binding protein 1 0.740
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.736
HLA-A major histocompatibility complex, class I, A 0.711
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.709
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.704
STAT1 signal transducer and activator of transcription 1, 91kDa 0.693
BLNK B-cell linker 0.689
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.687
BTN3A1 butyrophilin, subfamily 3, member A1 0.683
HLA-G major histocompatibility complex, class I, G 0.665
CARD11 caspase recruitment domain family, member 11 0.664
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.660
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.658
TLR2 toll-like receptor 2 0.630
SH2D1A SH2 domain containing 1A 0.620
HCK hemopoietic cell kinase 0.609
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.605
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.600
GHR growth hormone receptor 0.587
CD79A CD79a molecule, immunoglobulin-associated alpha 0.584
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.576
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.573
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.567
HLA-F major histocompatibility complex, class I, F 0.566
BTN3A3 butyrophilin, subfamily 3, member A3 0.562
RIPK2 receptor-interacting serine-threonine kinase 2 0.560
SQSTM1 sequestosome 1 0.534
TLR4 toll-like receptor 4 0.531
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.525
HLA-E major histocompatibility complex, class I, E 0.489
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.487
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.487
TNIP2 TNFAIP3 interacting protein 2 0.486
MAPK3 mitogen-activated protein kinase 3 0.486
PTPRJ protein tyrosine phosphatase, receptor type, J 0.480
SH3BP2 SH3-domain binding protein 2 0.474
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.457
MPDZ multiple PDZ domain protein 0.452
CYLD cylindromatosis (turban tumor syndrome) 0.448
S100A1 S100 calcium binding protein A1 0.446
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.436
BTN3A2 butyrophilin, subfamily 3, member A2 0.432
BCL10 B-cell CLL/lymphoma 10 0.425
CD22 CD22 molecule 0.404
ITK IL2-inducible T-cell kinase 0.402
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.393
FKBP4 FK506 binding protein 4, 59kDa 0.392
IGSF6 immunoglobulin superfamily, member 6 0.388
CCR1 chemokine (C-C motif) receptor 1 0.388
S100B S100 calcium binding protein B 0.387
TICAM2 toll-like receptor adaptor molecule 2 0.386
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.380
CD28 CD28 molecule 0.376
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.373
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Il2rg interleukin 2 receptor, gamma 0.702
Ptprc protein tyrosine phosphatase, receptor type, C 0.684
Igsf6 immunoglobulin superfamily, member 6 0.489
Cd53 Cd53 molecule 0.458
Arl11 ADP-ribosylation factor-like 11 0.429
Inpp5d inositol polyphosphate-5-phosphatase D 0.328
Arhgap25 Rho GTPase activating protein 25 0.318
Cd86 CD86 molecule 0.291
Hcls1 hematopoietic cell specific Lyn substrate 1 0.288
Hck hemopoietic cell kinase 0.262
Cd38 CD38 molecule 0.249
Myo1f myosin IF 0.223
Btk Bruton agammaglobulinemia tyrosine kinase 0.219
Clec4a3 C-type lectin domain family 4, member a3 0.173
Ctla2a cytotoxic T lymphocyte-associated protein 2 alpha 0.172
Sla src-like adaptor 0.167
Ccr5 chemokine (C-C motif) receptor 5 0.166
Dbp D site of albumin promoter (albumin D-box) binding protein 0.156
Il1b interleukin 1 beta 0.153
Casp1 caspase 1 0.151
Clec4a1 C-type lectin domain family 4, member a1 0.149
Ncf4 neutrophil cytosolic factor 4 0.136
Ptafr platelet-activating factor receptor 0.134
Cd37 CD37 molecule 0.132
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.128
Cybb cytochrome b-245, beta polypeptide 0.116
Lcp2 lymphocyte cytosolic protein 2 0.109
Slfn2 schlafen 2 0.098
Mca32 mast cell antigen 32 0.097
C5ar1 complement component 5a receptor 1 0.096
Ctse cathepsin E 0.093
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.090
Art2 ADP-ribosyltransferase 2 0.088
Cd3g CD3 molecule, gamma 0.085
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.084
LOC308990 hypothetical protein LOC308990 0.080
Cd247 Cd247 molecule 0.079
Ciita class II, major histocompatibility complex, transactivator 0.076
LOC100361706 lambda-chain C1-region-like 0.073
Ly86 lymphocyte antigen 86 0.072
Sash3 SAM and SH3 domain containing 3 0.071
Sell selectin L 0.070
Clec12a C-type lectin domain family 12, member A 0.069
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.067
Tlr4 toll-like receptor 4 0.067
Fcgr1a Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.064
Folr2 folate receptor 2 (fetal) 0.060
Irf5 interferon regulatory factor 5 0.059
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.058
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.057
Gpnmb glycoprotein (transmembrane) nmb 0.056
Cd2 Cd2 molecule 0.055
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.054
Cd8b CD8b molecule 0.054
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.054
Cxcl13 chemokine (C-X-C motif) ligand 13 0.054
Syk spleen tyrosine kinase 0.054
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.053
Ccl4 chemokine (C-C motif) ligand 4 0.050
Cst7 cystatin F (leukocystatin) 0.049
Lpxn leupaxin 0.048
LOC687856 similar to Myeloid cell surface antigen CD33 precursor (Siglec-3) 0.045
Alox5ap arachidonate 5-lipoxygenase activating protein 0.045
Lrrc33 leucine rich repeat containing 33 0.045
Slc15a3 solute carrier family 15, member 3 0.044
Slamf9 SLAM family member 9 0.041
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.039
Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 0.037
Cfp complement factor properdin 0.036
Arhgap9 Rho GTPase activating protein 9 0.036
Itgam integrin, alpha M 0.036
Batf basic leucine zipper transcription factor, ATF-like 0.035
Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon 0.035
Sirpa signal-regulatory protein alpha 0.034
Arl5c ADP-ribosylation factor-like 5C 0.034
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.034
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.034
Tlr7 toll-like receptor 7 0.033
Phemx pan hematopoietic expression 0.032
Sp140 SP140 nuclear body protein 0.031
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.031
Tnfaip8l2 tumor necrosis factor, alpha-induced protein 8-like 2 0.031
Fam113b family with sequence similarity 113, member B 0.030
Fgd2 FYVE, RhoGEF and PH domain containing 2 0.030
Lmo2 LIM domain only 2 0.030
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.030
Il7r interleukin 7 receptor 0.030
Stap1 signal transducing adaptor family member 1 0.029
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.029
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.029
Plcg2 phospholipase C, gamma 2 0.029
Cd22 CD22 molecule 0.028
Lpl lipoprotein lipase 0.028
Ccr1 chemokine (C-C motif) receptor 1 0.028
Il18 interleukin 18 0.028
Vcam1 vascular cell adhesion molecule 1 0.027
Sit1 signaling threshold regulating transmembrane adaptor 1 0.027
RGD1561143 similar to cell surface receptor FDFACT 0.027
Rgs1 regulator of G-protein signaling 1 0.027
Ripk3 receptor-interacting serine-threonine kinase 3 0.027
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism