Process View
The network for 'cd4 positive cd25 positive alpha beta regulatory t cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Ikzf1 | IKAROS family zinc finger 1 | 0.999 | |
Tcra | T-cell receptor alpha chain | 0.996 | |
Lat | linker for activation of T cells | 0.995 | |
Foxn1 | forkhead box N1 | 0.975 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.958 | |
Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.922 | |
Rag1 | recombination activating gene 1 | 0.921 | |
Cd247 | CD247 antigen | 0.894 | |
Ifng | interferon gamma | 0.842 | |
Rag2 | recombination activating gene 2 | 0.825 | |
Fyn | Fyn proto-oncogene | 0.782 | |
Lck | lymphocyte protein tyrosine kinase | 0.738 | |
Tnf | tumor necrosis factor | 0.690 | |
Foxp3 | forkhead box P3 | 0.649 | |
Il2 | interleukin 2 | 0.615 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.560 | |
Tcrd | T-cell receptor delta chain | 0.469 | |
Prf1 | perforin 1 (pore forming protein) | 0.401 | |
Cd19 | CD19 antigen | 0.335 | |
Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.326 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.314 | |
Trp53 | transformation related protein 53 | 0.307 | |
Il4 | interleukin 4 | 0.181 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.176 | |
Jak3 | Janus kinase 3 | 0.163 | |
Hdac7 | histone deacetylase 7 | 0.159 | |
Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.137 | |
Il10 | interleukin 10 | 0.103 | |
Zap70 | zeta-chain (TCR) associated protein kinase | 0.100 | |
Igh | immunoglobulin heavy chain complex | 0.096 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.090 | |
Cd28 | CD28 antigen | 0.085 | |
Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.076 | |
Il15 | interleukin 15 | 0.073 | |
Il2rb | interleukin 2 receptor, beta chain | 0.067 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.067 | |
Foxp1 | forkhead box P1 | 0.065 | |
Il7r | interleukin 7 receptor | 0.057 | |
Arid1a | AT rich interactive domain 1A (SWI-like) | 0.056 | |
Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) | 0.056 | |
B2m | beta-2 microglobulin | 0.056 | |
Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.051 | |
Ttc7 | tetratricopeptide repeat domain 7 | 0.051 | |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.046 | |
Card11 | caspase recruitment domain family, member 11 | 0.046 | |
Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.045 | |
Il2rg | interleukin 2 receptor, gamma chain | 0.043 | |
Lta | lymphotoxin A | 0.039 | |
Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.034 | |
Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.032 | |
Thra | thyroid hormone receptor alpha | 0.029 | |
Socs1 | suppressor of cytokine signaling 1 | 0.028 | |
Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.028 | |
Sin3a | transcriptional regulator, SIN3A (yeast) | 0.026 | |
Zfp362 | zinc finger protein 362 | 0.026 | |
Tnrc6c | trinucleotide repeat containing 6C | 0.026 | |
Cd4 | CD4 antigen | 0.026 | |
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.025 | |
Ccr7 | chemokine (C-C motif) receptor 7 | 0.025 | |
Hcst | hematopoietic cell signal transducer | 0.020 | |
Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.020 | |
Il6st | interleukin 6 signal transducer | 0.019 | |
Ash1l | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.018 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.018 | |
Apc | adenomatosis polyposis coli | 0.018 | |
Stat5a | signal transducer and activator of transcription 5A | 0.017 | |
Jak1 | Janus kinase 1 | 0.017 | |
Pten | phosphatase and tensin homolog | 0.016 | |
Bptf | bromodomain PHD finger transcription factor | 0.016 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.015 | |
Tgfb1 | transforming growth factor, beta 1 | 0.015 | |
Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.014 | |
Ciita | class II transactivator | 0.014 | |
Itk | IL2-inducible T-cell kinase | 0.013 | |
Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.013 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.013 | |
Cic | capicua homolog (Drosophila) | 0.013 | |
Lyst | lysosomal trafficking regulator | 0.012 | |
Zc3h11a | zinc finger CCCH type containing 11A | 0.012 | |
Igf2bp1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.012 | |
Hhex | hematopoietically expressed homeobox | 0.012 | |
Pou5f1 | POU domain, class 5, transcription factor 1 | 0.012 | |
Kit | kit oncogene | 0.012 | |
Ltb | lymphotoxin B | 0.012 | |
Crebbp | CREB binding protein | 0.012 | |
Arrdc3 | arrestin domain containing 3 | 0.012 | |
Runx1 | runt related transcription factor 1 | 0.011 | |
Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.011 | |
Smad1 | MAD homolog 1 (Drosophila) | 0.011 | |
Stim1 | stromal interaction molecule 1 | 0.011 | |
Hr | hairless | 0.011 | |
Plk1 | polo-like kinase 1 (Drosophila) | 0.011 | |
Batf | basic leucine zipper transcription factor, ATF-like | 0.010 | |
Tcf4 | transcription factor 4 | 0.010 | |
Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.010 | |
Zbtb20 | zinc finger and BTB domain containing 20 | 0.010 | |
Clcnka | chloride channel Ka | 0.010 | |
Prr12 | proline rich 12 | 0.010 | |
Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.010 |