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Process View

Mus musculus

19 genes annotated in mouse

b cell apoptotic process

Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "b cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "b cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.996
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.979
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.764
Igh	immunoglobulin heavy chain complex	0.762
Cd19	CD19 antigen	0.667
Was	Wiskott-Aldrich syndrome homolog (human)	0.658
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.647
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.607
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.568
Bcl2	B-cell leukemia/lymphoma 2	0.552	Mouse
Dok1	docking protein 1	0.441
Inpp5d	inositol polyphosphate-5-phosphatase D	0.424
Lta	lymphotoxin A	0.393
Ikzf1	IKAROS family zinc finger 1	0.358
Tnf	tumor necrosis factor	0.357
Cbl	Casitas B-lineage lymphoma	0.322
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.274
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.249
Kit	kit oncogene	0.245
Csf1	colony stimulating factor 1 (macrophage)	0.237
Traf2	TNF receptor-associated factor 2	0.227
Traf6	TNF receptor-associated factor 6	0.201
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.201
Plcg2	phospholipase C, gamma 2	0.179
Ifng	interferon gamma	0.175
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.160
Il1r1	interleukin 1 receptor, type I	0.146
Ltb	lymphotoxin B	0.123
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.118
Ptgs2	prostaglandin-endoperoxide synthase 2	0.117
Ptprc	protein tyrosine phosphatase, receptor type, C	0.113
Nos2	nitric oxide synthase 2, inducible	0.111
Tnip1	TNFAIP3 interacting protein 1	0.110
Ptk2	PTK2 protein tyrosine kinase 2	0.106
Dok2	docking protein 2	0.104
Cd40	CD40 antigen	0.103	Mouse
Tlr4	toll-like receptor 4	0.102
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.101
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.098
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.096
Ctnnb1	catenin (cadherin associated protein), beta 1	0.089
Irf8	interferon regulatory factor 8	0.088
Sfpi1	SFFV proviral integration 1	0.084
Lyz2	lysozyme 2	0.079
Sykb	spleen tyrosine kinase	0.077
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.076
Pou2af1	POU domain, class 2, associating factor 1	0.071
Prkcd	protein kinase C, delta	0.071
Lck	lymphocyte protein tyrosine kinase	0.068	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.068
Pxn	paxillin	0.059
Rgs14	regulator of G-protein signaling 14	0.058
Mmp9	matrix metallopeptidase 9	0.057
Blnk	B-cell linker	0.056
H2-DMa	histocompatibility 2, class II, locus DMa	0.051
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.051
Max	Max protein	0.050
Skil	SKI-like	0.048
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.048	Mouse
Cd4	CD4 antigen	0.047
Lep	leptin	0.046
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.046
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.046
Bach1	BTB and CNC homology 1	0.046
Klf6	Kruppel-like factor 6	0.045
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.045
Ptpre	protein tyrosine phosphatase, receptor type, E	0.044
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.043
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.043
Bbc3	BCL2 binding component 3	0.043
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.043
Wt1	Wilms tumor 1 homolog	0.042
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.041
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.041
Fas	Fas (TNF receptor superfamily member 6)	0.041
Ikzf3	IKAROS family zinc finger 3	0.041
Ccr7	chemokine (C-C motif) receptor 7	0.040
Clnk	cytokine-dependent hematopoietic cell linker	0.040
Ikbkg	inhibitor of kappaB kinase gamma	0.039
Il4	interleukin 4	0.039
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.038
H2-Eb1	histocompatibility 2, class II antigen E beta	0.038
Hcls1	hematopoietic cell specific Lyn substrate 1	0.037
Cd72	CD72 antigen	0.037
Bcl3	B-cell leukemia/lymphoma 3	0.037
Ccl2	chemokine (C-C motif) ligand 2	0.037
Ccr6	chemokine (C-C motif) receptor 6	0.037
Prkce	protein kinase C, epsilon	0.036
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.036
S1pr2	sphingosine-1-phosphate receptor 2	0.034
Icam1	intercellular adhesion molecule 1	0.034
Irf4	interferon regulatory factor 4	0.033
Bcar1	breast cancer anti-estrogen resistance 1	0.033
Grb2	growth factor receptor bound protein 2	0.033
Rac2	RAS-related C3 botulinum substrate 2	0.032
Ctsw	cathepsin W	0.032
Pten	phosphatase and tensin homolog	0.032
Meox2	mesenchyme homeobox 2	0.032
Il10	interleukin 10	0.031
Cd2ap	CD2-associated protein	0.031
Ep300	E1A binding protein p300	0.031
Dusp2	dual specificity phosphatase 2	0.030
Bax	BCL2-associated X protein	0.030
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.030
Irak3	interleukin-1 receptor-associated kinase 3	0.030
Plaur	plasminogen activator, urokinase receptor	0.030
Flcn	folliculin	0.029
Kitl	kit ligand	0.028
Card11	caspase recruitment domain family, member 11	0.028
Aicda	activation-induced cytidine deaminase	0.027
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.027
Bcl6	B-cell leukemia/lymphoma 6	0.027
Notch1	Notch gene homolog 1 (Drosophila)	0.026
E2f1	E2F transcription factor 1	0.026
Il17f	interleukin 17F	0.026
Pou3f4	POU domain, class 3, transcription factor 4	0.026
Huwe1	HECT, UBA and WWE domain containing 1	0.025
Cd8a	CD8 antigen, alpha chain	0.025
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.025
Tcra	T-cell receptor alpha chain	0.025
Gna13	guanine nucleotide binding protein, alpha 13	0.025
Smad3	MAD homolog 3 (Drosophila)	0.025
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.025
Tert	telomerase reverse transcriptase	0.024
Fcgr1	Fc receptor, IgG, high affinity I	0.024
Il6	interleukin 6	0.024
Ikbkb	inhibitor of kappaB kinase beta	0.024
Ifngr1	interferon gamma receptor 1	0.023
Jak3	Janus kinase 3	0.023
Hmha1	histocompatibility (minor) HA-1	0.023
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.023
Fbxo30	F-box protein 30	0.022
Trp73	transformation related protein 73	0.022
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.022	Mouse
Cxcr5	chemokine (C-X-C motif) receptor 5	0.022
Tubb4	tubulin, beta 4	0.022
Il2rg	interleukin 2 receptor, gamma chain	0.022
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.022
Vasp	vasodilator-stimulated phosphoprotein	0.022
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.022
Ubd	ubiquitin D	0.021
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.021
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.021
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.021	Mouse
Btg2	B-cell translocation gene 2, anti-proliferative	0.021
Tcrd	T-cell receptor delta chain	0.021
Lag3	lymphocyte-activation gene 3	0.021
Foxn1	forkhead box N1	0.020
Dll1	delta-like 1 (Drosophila)	0.020
Ikbke	inhibitor of kappaB kinase epsilon	0.020
Dok3	docking protein 3	0.020
Gzmb	granzyme B	0.020
Irs2	insulin receptor substrate 2	0.020
Bcl2l1	BCL2-like 1	0.020	Mouse
Btg1	B-cell translocation gene 1, anti-proliferative	0.020
Wnt6	wingless-related MMTV integration site 6	0.020
Bid	BH3 interacting domain death agonist	0.020
Notch2	Notch gene homolog 2 (Drosophila)	0.020
Hap1	huntingtin-associated protein 1	0.019
Il2rb	interleukin 2 receptor, beta chain	0.019
Lif	leukemia inhibitory factor	0.019
Sh2d2a	SH2 domain protein 2A	0.019	Mouse
Tcfap2c	transcription factor AP-2, gamma	0.019
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.019
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.019
Mocs1	molybdenum cofactor synthesis 1	0.019
Mcl1	myeloid cell leukemia sequence 1	0.018	Mouse
Lyst	lysosomal trafficking regulator	0.018
Gjb5	gap junction protein, beta 5	0.018
Zfp592	zinc finger protein 592	0.018
Cd40lg	CD40 ligand	0.018
Tlr2	toll-like receptor 2	0.018
Lepr	leptin receptor	0.018
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.018
Mc3r	melanocortin 3 receptor	0.018
Ticam1	toll-like receptor adaptor molecule 1	0.017
Ccl4	chemokine (C-C motif) ligand 4	0.017
Iqgap3	IQ motif containing GTPase activating protein 3	0.017
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.017
Kif2c	kinesin family member 2C	0.017
Tgif1	TGFB-induced factor homeobox 1	0.017
Runx1	runt related transcription factor 1	0.017
Cxcl13	chemokine (C-X-C motif) ligand 13	0.017
Spry4	sprouty homolog 4 (Drosophila)	0.017
Mrc1	mannose receptor, C type 1	0.017
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.017
S1pr4	sphingosine-1-phosphate receptor 4	0.017
Itgb7	integrin beta 7	0.016
Cd79b	CD79B antigen	0.016
Ghr	growth hormone receptor	0.016
Cd14	CD14 antigen	0.016
Bak1	BCL2-antagonist/killer 1	0.016
Mybl2	myeloblastosis oncogene-like 2	0.016
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.016
Cd8b1	CD8 antigen, beta chain 1	0.016
Fmnl1	formin-like 1	0.016
Bmf	BCL2 modifying factor	0.016
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.016
Apc	adenomatosis polyposis coli	0.016
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.015
Gpbp1	GC-rich promoter binding protein 1	0.015
Il6st	interleukin 6 signal transducer	0.015
Apoe	apolipoprotein E	0.015
Sox10	SRY-box containing gene 10	0.015
Itgal	integrin alpha L	0.015
Btk	Bruton agammaglobulinemia tyrosine kinase	0.015	Mouse
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.015
Spp1	secreted phosphoprotein 1	0.015
Pparg	peroxisome proliferator activated receptor gamma	0.015
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.015
Ncoa3	nuclear receptor coactivator 3	0.015
Il17ra	interleukin 17 receptor A	0.015
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.015
Myd88	myeloid differentiation primary response gene 88	0.015
Ciita	class II transactivator	0.015
Rbl1	retinoblastoma-like 1 (p107)	0.015
Socs1	suppressor of cytokine signaling 1	0.014
Gna15	guanine nucleotide binding protein, alpha 15	0.014
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.014
Ctnnd1	catenin (cadherin associated protein), delta 1	0.014
Duox2	dual oxidase 2	0.014
Cd37	CD37 antigen	0.014
Itga3	integrin alpha 3	0.014
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.014
Cd44	CD44 antigen	0.014
Mapk13	mitogen-activated protein kinase 13	0.014
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.014
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.014
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.014
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.014
Yap1	yes-associated protein 1	0.014
Esr1	estrogen receptor 1 (alpha)	0.014
Gab1	growth factor receptor bound protein 2-associated protein 1	0.013
Ly6d	lymphocyte antigen 6 complex, locus D	0.013
Gpr18	G protein-coupled receptor 18	0.013
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.013
Sh3bp2	SH3-domain binding protein 2	0.013
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.013
Mier3	mesoderm induction early response 1, family member 3	0.013
Diap1	diaphanous homolog 1 (Drosophila)	0.013
Mdm2	transformed mouse 3T3 cell double minute 2	0.013
H2-Oa	histocompatibility 2, O region alpha locus	0.013
Mier1	mesoderm induction early response 1 homolog (Xenopus laevis	0.013
Glipr2	GLI pathogenesis-related 2	0.013
Fam64a	family with sequence similarity 64, member A	0.013
Nhej1	nonhomologous end-joining factor 1	0.013
Clock	circadian locomotor output cycles kaput	0.013
Plscr1	phospholipid scramblase 1	0.013
Snx20	sorting nexin 20	0.013
Fcho1	FCH domain only 1	0.013
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.013
Npc1	Niemann Pick type C1	0.013
Cdc27	cell division cycle 27 homolog (S. cerevisiae)	0.013
Tcf7	transcription factor 7, T-cell specific	0.013
Adam17	a disintegrin and metallopeptidase domain 17	0.013
Ppard	peroxisome proliferator activator receptor delta	0.013
Bcl10	B-cell leukemia/lymphoma 10	0.013
Fpr1	formyl peptide receptor 1	0.012
Il27ra	interleukin 27 receptor, alpha	0.012
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.012
Mapk14	mitogen-activated protein kinase 14	0.012
Pax6	paired box gene 6	0.012
B630005N14Rik	RIKEN cDNA B630005N14 gene	0.012
Cdcp1	CUB domain containing protein 1	0.012
Pgm1	phosphoglucomutase 1	0.012
Mfn2	mitofusin 2	0.012
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012	Mouse
Pdcd1lg2	programmed cell death 1 ligand 2	0.012
Mvp	major vault protein	0.012
Wwtr1	WW domain containing transcription regulator 1	0.012
Ptpra	protein tyrosine phosphatase, receptor type, A	0.012
Folr4	folate receptor 4 (delta)	0.012
Pramel6	preferentially expressed antigen in melanoma like 6	0.012
Ticam2	toll-like receptor adaptor molecule 2	0.012
Cd7	CD7 antigen	0.012
Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a	0.012
Sprr2f	small proline-rich protein 2F	0.012
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.012
Cxcr4	chemokine (C-X-C motif) receptor 4	0.012
Ncr1	natural cytotoxicity triggering receptor 1	0.012
Lysmd3	LysM, putative peptidoglycan-binding, domain containing 3	0.012
Vcan	versican	0.012
Myc	myelocytomatosis oncogene	0.012
Zbtb7a	zinc finger and BTB domain containing 7a	0.012
Efs	embryonal Fyn-associated substrate	0.012
Hif1a	hypoxia inducible factor 1, alpha subunit	0.012
Irg1	immunoresponsive gene 1	0.012
Sox1	SRY-box containing gene 1	0.012
Slfn2	schlafen 2	0.011
Vdr	vitamin D receptor	0.011
Il10ra	interleukin 10 receptor, alpha	0.011
Krt33a	keratin 33A	0.011
Rab8b	RAB8B, member RAS oncogene family	0.011
Sat1	spermidine/spermine N1-acetyl transferase 1	0.011
Plagl1	pleiomorphic adenoma gene-like 1	0.011
Src	Rous sarcoma oncogene	0.011	Mouse
Gpr97	G protein-coupled receptor 97	0.011
Mov10	Moloney leukemia virus 10	0.011
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.011
Irf1	interferon regulatory factor 1	0.011
Fcho2	FCH domain only 2	0.011
Siglece	sialic acid binding Ig-like lectin E	0.011
Smad4	MAD homolog 4 (Drosophila)	0.011
Sry	sex determining region of Chr Y	0.011
Ptf1a	pancreas specific transcription factor, 1a	0.011
Il20	interleukin 20	0.011
Csf1r	colony stimulating factor 1 receptor	0.011
Phf17	PHD finger protein 17	0.011
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.011
Zap70	zeta-chain (TCR) associated protein kinase	0.011
Ccr2	chemokine (C-C motif) receptor 2	0.011
Fes	feline sarcoma oncogene	0.011
Skap2	src family associated phosphoprotein 2	0.011
Ebi3	Epstein-Barr virus induced gene 3	0.011
Ccl22	chemokine (C-C motif) ligand 22	0.011
2010109K11Rik	RIKEN cDNA 2010109K11 gene	0.011
Emid2	EMI domain containing 2	0.011
Ncf1	neutrophil cytosolic factor 1	0.011
Pvrl2	poliovirus receptor-related 2	0.011
Nkx2-1	NK2 homeobox 1	0.011
Thbs1	thrombospondin 1	0.011
Ccl5	chemokine (C-C motif) ligand 5	0.011
Fasl	Fas ligand (TNF superfamily, member 6)	0.011
Nphs2	nephrosis 2 homolog, podocin (human)	0.011
Lhx3	LIM homeobox protein 3	0.010
Met	met proto-oncogene	0.010
Cd2	CD2 antigen	0.010
Tmod3	tropomodulin 3	0.010
Snai1	snail homolog 1 (Drosophila)	0.010
Pou2f2	POU domain, class 2, transcription factor 2	0.010
Fyb	FYN binding protein	0.010
Vhl	von Hippel-Lindau tumor suppressor	0.010
Nphs1	nephrosis 1 homolog, nephrin (human)	0.010
Gdnf	glial cell line derived neurotrophic factor	0.010
Stat3	signal transducer and activator of transcription 3	0.010
BC013712	cDNA sequence BC013712	0.010
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.010
Ccnd1	cyclin D1	0.010
Ret	ret proto-oncogene	0.010
Amhr2	anti-Mullerian hormone type 2 receptor	0.010
Pim1	proviral integration site 1	0.010
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.010
Eda	ectodysplasin-A	0.010
Hmox1	heme oxygenase (decycling) 1	0.010
Egfr	epidermal growth factor receptor	0.010