The network for 'regulation of lymphocyte proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Lyz2 lysozyme 2 0.999
Tnf tumor necrosis factor 0.999
Efnb2 ephrin B2 0.998
Pten phosphatase and tensin homolog 0.997
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.996
Cd19 CD19 antigen 0.995
Il4 interleukin 4 0.995
Tlr4 toll-like receptor 4 0.988
Ccr2 chemokine (C-C motif) receptor 2 0.986
Fas Fas (TNF receptor superfamily member 6) 0.985
Cd40 CD40 antigen 0.984
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.983
Trp53 transformation related protein 53 0.979
Stat3 signal transducer and activator of transcription 3 0.977
Ctnnb1 catenin (cadherin associated protein), beta 1 0.971
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.969
Foxp3 forkhead box P3 0.967
Cd28 CD28 antigen 0.964
Lepr leptin receptor 0.963
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.954
Myd88 myeloid differentiation primary response gene 88 0.950
Igh immunoglobulin heavy chain complex 0.940
Inpp5d inositol polyphosphate-5-phosphatase D 0.938
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.921
Ccr1 chemokine (C-C motif) receptor 1 0.917
Ikzf1 IKAROS family zinc finger 1 0.907
Foxc1 forkhead box C1 0.899
Fyn Fyn proto-oncogene 0.893
Clec4n C-type lectin domain family 4, member n 0.887
Rb1 retinoblastoma 1 0.878
Nckap1l NCK associated protein 1 like 0.877
Grb2 growth factor receptor bound protein 2 0.871
Prkcd protein kinase C, delta 0.852
Pax8 paired box gene 8 0.847
Ccr7 chemokine (C-C motif) receptor 7 0.846
Nf1 neurofibromatosis 1 0.834
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.831
Fgfr2 fibroblast growth factor receptor 2 0.829
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.827
Cd4 CD4 antigen 0.824
Ccl2 chemokine (C-C motif) ligand 2 0.814
Cyld cylindromatosis (turban tumor syndrome) 0.810
Cbl Casitas B-lineage lymphoma 0.803
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.795
C3ar1 complement component 3a receptor 1 0.793
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.791
Il10 interleukin 10 0.780
Ltb lymphotoxin B 0.776
Casp1 caspase 1 0.773
Ifng interferon gamma 0.771
Zeb1 zinc finger E-box binding homeobox 1 0.763
Irf4 interferon regulatory factor 4 0.762
Btk Bruton agammaglobulinemia tyrosine kinase 0.760
Lta lymphotoxin A 0.740
Emx1 empty spiracles homolog 1 (Drosophila) 0.738
Hif1a hypoxia inducible factor 1, alpha subunit 0.735
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.735
Card11 caspase recruitment domain family, member 11 0.726
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.722
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.717
Egfr epidermal growth factor receptor 0.716
Drd2 dopamine receptor D2 0.715
Rag1 recombination activating gene 1 0.710
Batf basic leucine zipper transcription factor, ATF-like 0.702
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.701
Pdcd1 programmed cell death 1 0.691
Lhx3 LIM homeobox protein 3 0.681
Birc3 baculoviral IAP repeat-containing 3 0.679
Ticam1 toll-like receptor adaptor molecule 1 0.663
H2-Aa histocompatibility 2, class II antigen A, alpha 0.657
Apc adenomatosis polyposis coli 0.646
Fasl Fas ligand (TNF superfamily, member 6) 0.643
Mmp9 matrix metallopeptidase 9 0.631
Cd22 CD22 antigen 0.628
Nos1 nitric oxide synthase 1, neuronal 0.625
Ptprc protein tyrosine phosphatase, receptor type, C 0.622
Icos inducible T-cell co-stimulator 0.618
Fcgr2b Fc receptor, IgG, low affinity IIb 0.607
Gli3 GLI-Kruppel family member GLI3 0.601
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.600
Il6 interleukin 6 0.599
Cd160 CD160 antigen 0.596
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.595
Clec4d C-type lectin domain family 4, member d 0.594
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.573
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.572
Casp8 caspase 8 0.566
Il1r1 interleukin 1 receptor, type I 0.564
Esr1 estrogen receptor 1 (alpha) 0.564
Meox2 mesenchyme homeobox 2 0.560
Sfpi1 SFFV proviral integration 1 0.556
Foxn1 forkhead box N1 0.555
Stat5b signal transducer and activator of transcription 5B 0.552
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.540
Il27ra interleukin 27 receptor, alpha 0.535
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.532
Cd96 CD96 antigen 0.530
Rarg retinoic acid receptor, gamma 0.528
Stat1 signal transducer and activator of transcription 1 0.525
Ntf3 neurotrophin 3 0.523
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.991
CD80 CD80 molecule 0.967
FGFR2 fibroblast growth factor receptor 2 0.966
LAT linker for activation of T cells 0.961
BCL2 B-cell CLL/lymphoma 2 0.961
PTPRC protein tyrosine phosphatase, receptor type, C 0.952
CD86 CD86 molecule 0.947
HLA-DRA major histocompatibility complex, class II, DR alpha 0.933
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.912
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.912
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.894
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.889
SOCS3 suppressor of cytokine signaling 3 0.865
HLA-DMA major histocompatibility complex, class II, DM alpha 0.865
SYK spleen tyrosine kinase 0.864
TRAF1 TNF receptor-associated factor 1 0.853
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.852
HLA-F major histocompatibility complex, class I, F 0.851
IL1B interleukin 1, beta 0.848
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.839
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.835
B2M beta-2-microglobulin 0.829
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.826
HLA-DMB major histocompatibility complex, class II, DM beta 0.823
BIRC3 baculoviral IAP repeat containing 3 0.821
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.811
TRAF2 TNF receptor-associated factor 2 0.789
IL4R interleukin 4 receptor 0.785
HLA-G major histocompatibility complex, class I, G 0.779
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.769
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.769
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.766
HLA-B major histocompatibility complex, class I, B 0.764
LCK lymphocyte-specific protein tyrosine kinase 0.739
ICAM1 intercellular adhesion molecule 1 0.711
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.695
SH3BP2 SH3-domain binding protein 2 0.686
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.672
SLA Src-like-adaptor 0.669
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.667
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.659
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.651
BTN3A1 butyrophilin, subfamily 3, member A1 0.636
IL10RA interleukin 10 receptor, alpha 0.613
IL1R1 interleukin 1 receptor, type I 0.605
BTN3A3 butyrophilin, subfamily 3, member A3 0.573
TICAM2 toll-like receptor adaptor molecule 2 0.568
EGFR epidermal growth factor receptor 0.530
CD247 CD247 molecule 0.524
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.517
BTN3A2 butyrophilin, subfamily 3, member A2 0.515
PLCG1 phospholipase C, gamma 1 0.488
CCR1 chemokine (C-C motif) receptor 1 0.481
CCL4 chemokine (C-C motif) ligand 4 0.471
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.468
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.464
HLA-E major histocompatibility complex, class I, E 0.463
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.457
IL2RG interleukin 2 receptor, gamma 0.432
CCR5 chemokine (C-C motif) receptor 5 0.431
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.430
TFF1 trefoil factor 1 0.417
RHOU ras homolog gene family, member U 0.413
FGFR1 fibroblast growth factor receptor 1 0.406
CXCL9 chemokine (C-X-C motif) ligand 9 0.398
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.392
FGF1 fibroblast growth factor 1 (acidic) 0.391
JAK1 Janus kinase 1 0.383
CCR7 chemokine (C-C motif) receptor 7 0.367
SIGLEC7 sialic acid binding Ig-like lectin 7 0.364
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.360
CCL2 chemokine (C-C motif) ligand 2 0.346
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.344
JAK2 Janus kinase 2 0.336
IRF4 interferon regulatory factor 4 0.334
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.334
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.325
INSR insulin receptor 0.321
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.320
BID BH3 interacting domain death agonist 0.319
HLA-C major histocompatibility complex, class I, C 0.318
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.307
IFNG interferon, gamma 0.302
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.299
IL2RB interleukin 2 receptor, beta 0.299
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.297
HCK hemopoietic cell kinase 0.295
IRAK1 interleukin-1 receptor-associated kinase 1 0.281
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.273
GRB2 growth factor receptor-bound protein 2 0.270
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.265
CLEC10A C-type lectin domain family 10, member A 0.262
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.260
ABI1 abl-interactor 1 0.259
BCL2A1 BCL2-related protein A1 0.252
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.252
IL6 interleukin 6 (interferon, beta 2) 0.246
IRS1 insulin receptor substrate 1 0.244
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.243
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.242
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Da RT1 class II, locus Da 0.768
RT1-Ba RT1 class II, locus Ba 0.688
RT1-Bb RT1 class II, locus Bb 0.423
Cd44 Cd44 molecule 0.273
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.238
RT1-Db1 RT1 class II, locus Db1 0.235
Cd37 CD37 molecule 0.235
Cd247 Cd247 molecule 0.150
RT1-DMb RT1 class II, locus DMb 0.116
RT1-DMa RT1 class II, locus DMa 0.101
Cd2 Cd2 molecule 0.080
Il10 interleukin 10 0.077
Ciita class II, major histocompatibility complex, transactivator 0.074
Laptm5 lysosomal protein transmembrane 5 0.054
Ptprc protein tyrosine phosphatase, receptor type, C 0.050
Cd53 Cd53 molecule 0.050
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.048
Tas2r123 taste receptor, type 2, member 123 0.048
Hck hemopoietic cell kinase 0.046
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.045
Lyz2 lysozyme 2 0.044
Cd38 CD38 molecule 0.044
Il1b interleukin 1 beta 0.040
Aif1 allograft inflammatory factor 1 0.040
Arhgap4 Rho GTPase activating protein 4 0.039
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.037
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.036
Inpp5d inositol polyphosphate-5-phosphatase D 0.035
Casp1 caspase 1 0.034
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.034
Lcp2 lymphocyte cytosolic protein 2 0.032
Anxa2 annexin A2 0.031
Cd5 Cd5 molecule 0.030
Arpc1b actin related protein 2/3 complex, subunit 1B 0.030
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.029
Cp ceruloplasmin 0.029
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.028
Ctss cathepsin S 0.026
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.026
Cfp complement factor properdin 0.026
Il1rl1 interleukin 1 receptor-like 1 0.026
Serpinb1a serine (or cysteine) proteinase inhibitor, clade B, member 1a 0.026
Spn sialophorin 0.025
Slfn2 schlafen 2 0.025
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.025
Ppyr1 pancreatic polypeptide receptor 1 0.023
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.023
Il2rb interleukin 2 receptor, beta 0.023
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.023
Ptafr platelet-activating factor receptor 0.022
Il18 interleukin 18 0.022
Mmp10 matrix metallopeptidase 10 0.021
Lef1 lymphoid enhancer binding factor 1 0.021
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.021
RGD1559588 similar to cell surface receptor FDFACT 0.020
Plac8 placenta-specific 8 0.020
Gzmk granzyme K 0.019
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.019
Itgb7 integrin, beta 7 0.019
Itgad integrin, alpha D 0.019
Ptprq protein tyrosine phosphatase, receptor type, Q 0.018
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.018
Ccr5 chemokine (C-C motif) receptor 5 0.017
Nkg7 natural killer cell group 7 sequence 0.016
Zbp1 Z-DNA binding protein 1 0.016
Mep1a meprin 1 alpha 0.016
Alox5ap arachidonate 5-lipoxygenase activating protein 0.016
Scn11a sodium channel, voltage-gated, type XI, alpha 0.016
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.016
Hmox1 heme oxygenase (decycling) 1 0.016
Skap2 src kinase associated phosphoprotein 2 0.016
Gpr114 G protein-coupled receptor 114 0.016
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.016
Syt8 synaptotagmin VIII 0.015
Cd200r1 CD200 receptor 1 0.015
Il6 interleukin 6 0.015
Impg2 interphotoreceptor matrix proteoglycan 2 0.015
Kl Klotho 0.015
Myo1g myosin IG 0.015
Sell selectin L 0.015
Jak1 Janus kinase 1 0.015
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.015
Met met proto-oncogene 0.015
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.015
Ereg epiregulin 0.015
MGC112715 hypothetical protein LOC690899 0.015
Kcnv1 potassium channel, subfamily V, member 1 0.014
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.014
Kcng3 potassium voltage-gated channel, subfamily G, member 3 0.014
Fgf11 fibroblast growth factor 11 0.014
Napsa napsin A aspartic peptidase 0.014
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.014
Rt1.aa MHC class I RT1.Aa alpha-chain 0.014
Gfap glial fibrillary acidic protein 0.014
Gpr20 G protein-coupled receptor 20 0.014
Olr1466 olfactory receptor 1466 0.014
C1qb complement component 1, q subcomponent, B chain 0.014
Ccl5 chemokine (C-C motif) ligand 5 0.013
Col10a1 collagen, type X, alpha 1 0.013
Ncf4 neutrophil cytosolic factor 4 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism