IMP

Process View

Drosophila melanogaster

29 genes annotated in fly

response to insulin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to insulin"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to insulin" (in gray)

Name	Description	Probability	Func Analog Organism
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.959
Ilp5	Insulin-like peptide 5	0.786	Fly
Pk61C	Protein kinase 61C	0.594	Human
Ras85D	Ras oncogene at 85D	0.586
Ilp2	Insulin-like peptide 2	0.426
S6k	RPS6-p70-protein kinase	0.425	Human Rat
sNPF-R	short neuropeptide F receptor	0.383
Rheb	CG1081 gene product from transcript CG1081-RA	0.348
Rac1	CG2248 gene product from transcript CG2248-RA	0.296
dm	diminutive	0.251
spi	spitz	0.251
InR	Insulin-like receptor	0.245
CycG	Cyclin G	0.202
Lnk	CG17367 gene product from transcript CG17367-RC	0.182
Thor	CG8846 gene product from transcript CG8846-RA	0.169
dco	discs overgrown	0.163
Ilp6	Insulin-like peptide 6	0.157
Tequila	CG4821 gene product from transcript CG4821-RE	0.155
Akt1	CG4006 gene product from transcript CG4006-RA	0.152
drk	downstream of receptor kinase	0.143	Human
Mad	Mothers against dpp	0.141
kis	kismet	0.125
if	inflated	0.120
CG13253	CG13253 gene product from transcript CG13253-RB	0.117
CdsA	CDP diglyceride synthetase	0.112
pico	CG11940 gene product from transcript CG11940-RA	0.111
foxo	forkhead box, sub-group O	0.111
scyl	scylla	0.103
ppk	pickpocket	0.089
Pka-C1	cAMP-dependent protein kinase 1	0.088
Pdp1	PAR-domain protein 1	0.088
jeb	jelly belly	0.087
Ilp3	Insulin-like peptide 3	0.082	Fly
mbc	myoblast city	0.082
trp	transient receptor potential	0.080
blw	bellwether	0.079
Tor	Target of rapamycin	0.073	Mouse
Patr-1	Protein associated with topo II related - 1	0.072
kst	karst	0.069
Lsd-1	Lipid storage droplet-1	0.069
dib	disembodied	0.067
sev	sevenless	0.067	Fly
ImpL2	Ecdysone-inducible gene L2	0.066
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.065
shg	shotgun	0.058
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.058
rictor	rapamycin-insensitive companion of Tor	0.057
rols	rolling pebbles	0.056
fkh	fork head	0.054
Mnt	CG13316 gene product from transcript CG13316-RD	0.054
melt	melted	0.053
Gsc	Goosecoid	0.052
Cdk4	Cyclin-dependent kinase 4	0.052
mav	maverick	0.052
rdgB	retinal degeneration B	0.051
gcm	glial cells missing	0.051
Pgi	Phosphoglucose isomerase	0.050
CG3004	CG3004 gene product from transcript CG3004-RA	0.050
Kr-h1	Kruppel homolog 1	0.048
rho	rhomboid	0.047
norpA	no receptor potential A	0.047
put	punt	0.047
gig	gigas	0.047
Gyc76C	Guanylyl cyclase at 76C	0.046
BHD	Birt-Hogg-Dube homolog	0.045
Vha68-1	CG12403 gene product from transcript CG12403-RA	0.045
Ork1	Open rectifier K[+] channel 1	0.045
rl	rolled	0.044
Pten	CG5671 gene product from transcript CG5671-RB	0.044
btsz	bitesize	0.043
CG13890	CG13890 gene product from transcript CG13890-RA	0.042
ftz-f1	ftz transcription factor 1	0.042
CG14869	CG14869 gene product from transcript CG14869-RB	0.040
Ilp7	Insulin-like peptide 7	0.040
Rack1	Receptor of activated protein kinase C 1	0.040
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.040
Fatp	Fatty acid (long chain) transport protein	0.039	Mouse
B4	CG9239 gene product from transcript CG9239-RA	0.039
chico	CG5686 gene product from transcript CG5686-RB	0.038
Gclc	Glutamate-cysteine ligase catalytic subunit	0.038
daw	dawdle	0.038
Myo31DF	Myosin 31DF	0.038
ash2	absent, small, or homeotic discs 2	0.037
lkb1	CG9374 gene product from transcript CG9374-RJ	0.036
Mob2	CG11711 gene product from transcript CG11711-RC	0.036
RanBPM	Ran-binding protein M	0.035
rap	retina aberrant in pattern	0.035
Dsk	Drosulfakinin	0.035
CycD	Cyclin D	0.034	Rat
phl	pole hole	0.034
path	pathetic	0.034
boss	bride of sevenless	0.034
Pak	PAK-kinase	0.034	Rat
Krn	Keren	0.032
neuroligin	CG13772 gene product from transcript CG13772-RA	0.032
Gycalpha99B	Guanylyl cyclase alpha-subunit at 99B	0.032
CtBP	C-terminal Binding Protein	0.031
HLH106	Helix loop helix protein 106	0.031
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.031
rdgA	retinal degeneration A	0.030
hpo	hippo	0.030
ey	eyeless	0.029	Rat
Rho1	CG8416 gene product from transcript CG8416-RB	0.029
CG8090	CG8090 gene product from transcript CG8090-RB	0.029
pros	prospero	0.029
Indy	I'm not dead yet	0.028
RpS6	Ribosomal protein S6	0.028
Hem	HEM-protein	0.028
Cyp6t3	CG8457 gene product from transcript CG8457-RA	0.028
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.028
tai	taiman	0.028
Tbh	Tyramine beta hydroxylase	0.027
klg	klingon	0.027
ns3	nucleostemin 3	0.027
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.027	Rat
cpb	capping protein beta	0.027
nwk	nervous wreck	0.027
vri	vrille	0.027
CG1607	CG1607 gene product from transcript CG1607-RA	0.027
Nf1	Neurofibromin 1	0.026
Rdl	Resistant to dieldrin	0.025
sav	salvador	0.025
ttv	tout-velu	0.025
CG3590	CG3590 gene product from transcript CG3590-RA	0.025
Cdc42	CG12530 gene product from transcript CG12530-RA	0.025
Spargel	CG9809 gene product from transcript CG9809-RB	0.025
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.024
CG14815	CG14815 gene product from transcript CG14815-RA	0.024
Pde1c	Phosphodiesterase 1c	0.024
klar	klarsicht	0.024
CG11255	CG11255 gene product from transcript CG11255-RA	0.024
RpI135	RNA polymerase I 135kD subunit	0.024
frj	farjavit	0.024
Bre1	CG10542 gene product from transcript CG10542-RA	0.024
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.024
skap	skpA associated protein	0.023
Pink1	PTEN-induced putative kinase 1	0.023
CG8709	CG8709 gene product from transcript CG8709-RK	0.023
CG32418	CG32418 gene product from transcript CG32418-RA	0.023
msn	misshapen	0.023
inaE	inactivation no afterpotential E	0.023
chrb	charybde	0.022
CG3847	CG3847 gene product from transcript CG3847-RA	0.022
sro	shroud	0.022
sxc	super sex combs	0.022
Pdf	Pigment-dispersing factor	0.022
ssh	slingshot	0.022
CG10083	CG10083 gene product from transcript CG10083-RA	0.021
CG3837	CG3837 gene product from transcript CG3837-RA	0.021
Caki	Calcium/calmodulin-dependent protein kinase	0.021
CG8654	CG8654 gene product from transcript CG8654-RA	0.021
Ras64B	Ras oncogene at 64B	0.021
CCKLR-17D1	CCK-like receptor at 17D1	0.021
stai	stathmin	0.021
retn	retained	0.020
pip	pipe	0.020
CG9316	CG9316 gene product from transcript CG9316-RA	0.020
Ets97D	Ets at 97D	0.020
CG42629	CG42629 gene product from transcript CG42629-RB	0.020
cnk	connector enhancer of ksr	0.020
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.020
CG42672	CG42672 gene product from transcript CG42672-RD	0.020
CG3308	CG3308 gene product from transcript CG3308-RA	0.020
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.020
Sir2	CG5216 gene product from transcript CG5216-RA	0.019	Human Mouse
p53	CG33336 gene product from transcript CG33336-RB	0.019
EcR	Ecdysone receptor	0.019
step	steppke	0.019
CG18317	CG18317 gene product from transcript CG18317-RA	0.019
Nrx-IV	Neurexin IV	0.019
csw	corkscrew	0.019	Human
CG14937	CG14937 gene product from transcript CG14937-RA	0.019
Vinc	Vinculin	0.018
byn	brachyenteron	0.018
Su(dx)	Suppressor of deltex	0.018
erm	earmuff	0.018
CG4853	CG4853 gene product from transcript CG4853-RA	0.018
dnt	doughnut on 2	0.018
mys	myospheroid	0.018
toy	twin of eyeless	0.018	Rat
RpS30	Ribosomal protein S30	0.018
Caps	Calcium activated protein for secretion	0.017
oa2	octopamine receptor 2	0.017	Rat
sim	single-minded	0.017	Fly
cln3	CG5582 gene product from transcript CG5582-RA	0.017
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.017
Pp2B-14D	Protein phosphatase 2B at 14D	0.017
ort	ora transientless	0.017
CG6439	CG6439 gene product from transcript CG6439-RA	0.017
CG31637	CG31637 gene product from transcript CG31637-RA	0.017
CG14059	CG14059 gene product from transcript CG14059-RB	0.017
Ptth	Prothoracicotropic hormone	0.017
dock	dreadlocks	0.017
NLaz	Neural Lazarillo	0.017
not	non-stop	0.017
ninaB	neither inactivation nor afterpotential B	0.017	Mouse
Treh	Trehalase	0.017
tsl	torso-like	0.017
Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.016
ntc	nutcracker	0.016
Jarid2	CG3654 gene product from transcript CG3654-RD	0.016
ImpL3	Ecdysone-inducible gene L3	0.016
cher	cheerio	0.016
AcCoAS	Acetyl Coenzyme A synthase	0.016
shd	shade	0.016
wb	wing blister	0.016
hth	homothorax	0.016
Naam	Nicotinamide amidase	0.016
bnl	branchless	0.016
inaD	inactivation no afterpotential D	0.016
CG9527	CG9527 gene product from transcript CG9527-RA	0.015
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.015	Mouse Rat Worm
rab3-GAP	CG7061 gene product from transcript CG7061-RA	0.015
otk	off-track	0.015
ttm50	tiny tim 50	0.015
cdi	center divider	0.015
jagn	jagunal	0.015
t	tan	0.015
bib	big brain	0.015
Irk3	Inwardly rectifying potassium channel 3	0.015
Lerp	lysosomal enzyme receptor protein	0.015
Pfrx	6-phosphofructo-2-kinase	0.015
tau	CG31057 gene product from transcript CG31057-RA	0.015
trpl	trp-like	0.015
CG4289	CG4289 gene product from transcript CG4289-RA	0.015
CG7145	CG7145 gene product from transcript CG7145-RD	0.015
Kr	Kruppel	0.015
PGRP-SC2	CG14745 gene product from transcript CG14745-RA	0.015
bsk	basket	0.014
ple	pale	0.014
ClC-c	Chloride channel-c	0.014
Lis-1	Lissencephaly-1	0.014
trio	CG18214 gene product from transcript CG18214-RA	0.014
MTF-1	Metal response element-binding Transcription Factor-1	0.014
ninaA	neither inactivation nor afterpotential A	0.014
bun	bunched	0.014
cutlet	CG33122 gene product from transcript CG33122-RA	0.014
RN-tre	tre oncogene-related protein	0.014
bowl	brother of odd with entrails limited	0.014
Nhe2	Na[+]/H[+] hydrogen exchanger 2	0.014
CG4495	CG4495 gene product from transcript CG4495-RA	0.014
Pph13	PvuII-PstI homology 13	0.014
CG31999	CG31999 gene product from transcript CG31999-RA	0.014
Atg18	Autophagy-specific gene 18	0.014
Dad	Daughters against dpp	0.014
CG1972	CG1972 gene product from transcript CG1972-RA	0.014
CG8155	CG8155 gene product from transcript CG8155-RA	0.014
Jra	Jun-related antigen	0.013
CG8677	CG8677 gene product from transcript CG8677-RA	0.013
CG18135	CG18135 gene product from transcript CG18135-RC	0.013
Pur-alpha	Purine-rich binding protein-alpha	0.013
brat	brain tumor	0.013
TfIIS	RNA polymerase II elongation factor	0.013
CG9904	CG9904 gene product from transcript CG9904-RA	0.013
Pdh	Photoreceptor dehydrogenase	0.013
Hr96	Hormone receptor-like in 96	0.013
Met	Methoprene-tolerant	0.013
CG3036	CG3036 gene product from transcript CG3036-RA	0.013
cdc2c	CG10498 gene product from transcript CG10498-RC	0.013	Rat
rhea	CG6831 gene product from transcript CG6831-RA	0.013
skpA	CG16983 gene product from transcript CG16983-RD	0.013
JhI-1	Juvenile hormone-inducible protein 1	0.013
SNF1A	SNF1A/AMP-activated protein kinase	0.013	Rat
Max	CG9648 gene product from transcript CG9648-RA	0.013	Rat
Z600	CG17962 gene product from transcript CG17962-RA	0.013
CG9541	CG9541 gene product from transcript CG9541-RA	0.013
CG14317	CG14317 gene product from transcript CG14317-RA	0.013
CG1041	CG1041 gene product from transcript CG1041-RA	0.013
hipk	homeodomain interacting protein kinase	0.013
CG11436	CG11436 gene product from transcript CG11436-RA	0.013
AdoR	Adenosine receptor	0.013
bin	biniou	0.013
Oatp74D	Organic anion transporting polypeptide 74D	0.013
vig	vasa intronic gene	0.013
CG11399	CG11399 gene product from transcript CG11399-RB	0.012
CG31531	CG31531 gene product from transcript CG31531-RC	0.012
lok	loki	0.012
CG6800	CG6800 gene product from transcript CG6800-RA	0.012
Hph	HIF prolyl hydroxylase	0.012
egl	egalitarian	0.012
Cyp6g1	CG8453 gene product from transcript CG8453-RA	0.012
eve	even skipped	0.012
Ilp4	Insulin-like peptide 4	0.012	Fly
CG2316	CG2316 gene product from transcript CG2316-RD	0.012
nullo	CG14426 gene product from transcript CG14426-RB	0.012
lft	lowfat	0.012
p38b	CG7393 gene product from transcript CG7393-RA	0.012
alpha-Man-I	alpha Mannosidase I	0.012
mew	multiple edematous wings	0.012
Marf	Mitochondrial assembly regulatory factor	0.012
CG5028	CG5028 gene product from transcript CG5028-RB	0.012
Aats-met	Methionyl-tRNA synthetase	0.012
CG11055	CG11055 gene product from transcript CG11055-RB	0.012
EDTP	Egg-derived tyrosine phosphatase	0.012
Vang	Van Gogh	0.012
CkIIbeta	Casein kinase II beta subunit	0.012
Ctr1A	Copper transporter 1A	0.012
NTPase	CG3059 gene product from transcript CG3059-RD	0.012
Aats-leu	Leucyl-tRNA synthetase	0.012
Cpr	Cytochrome P450 reductase	0.012
hep	hemipterous	0.012
dnr1	defense repressor 1	0.012
Pabp2	CG2163 gene product from transcript CG2163-RA	0.012
G-oalpha47A	G protein oalpha 47A	0.012
Aef1	Adult enhancer factor 1	0.012
Gadd45	CG11086 gene product from transcript CG11086-RA	0.012
argos	CG4531 gene product from transcript CG4531-RA	0.012
sing	singles bar	0.012
katanin-60	katanin 60	0.012
Nmda1	N-methyl-D-aspartate receptor-associated protein	0.012
NPFR1	neuropeptide F receptor	0.011
Prx2540-1	Peroxiredoxin 2540	0.011
shi	shibire	0.011
CG10916	CG10916 gene product from transcript CG10916-RA	0.011
Ac76E	Adenylyl cyclase 76E	0.011
htl	heartless	0.011
nej	nejire	0.011
drpr	draper	0.011
CG12229	CG12229 gene product from transcript CG12229-RA	0.011
sna	snail	0.011
Sos	Son of sevenless	0.011
Oamb	Octopamine receptor in mushroom bodies	0.011
Xrp1	CG17836 gene product from transcript CG17836-RB	0.011
Pka-R1	cAMP-dependent protein kinase R1	0.011
CG4714	CG4714 gene product from transcript CG4714-RA	0.011
Syb	Synaptobrevin	0.011
Sin3A	CG8815 gene product from transcript CG8815-RC	0.011
Ppat-Dpck	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase	0.011
sli	slit	0.011
btl	breathless	0.011
Ptp10D	Protein tyrosine phosphatase 10D	0.011
capt	capulet	0.011
Atg4	Autophagy-specific gene 4	0.011
CG13022	CG13022 gene product from transcript CG13022-RB	0.011
ths	thisbe	0.011
na	narrow abdomen	0.011
CG14053	CG14053 gene product from transcript CG14053-RA	0.011
S6kII	RPS6-protein kinase-II	0.011
CG5261	CG5261 gene product from transcript CG5261-RB	0.011
CG3726	CG3726 gene product from transcript CG3726-RA	0.011
Gug	Grunge	0.011
CG33138	CG33138 gene product from transcript CG33138-RA	0.011
mnb	minibrain	0.011
CG10154	CG10154 gene product from transcript CG10154-RA	0.011
CG3967	CG3967 gene product from transcript CG3967-RC	0.011
jub	Ajuba LIM protein	0.010
CG8451	CG8451 gene product from transcript CG8451-RA	0.010
CycJ	Cyclin J	0.010
fh	frataxin homolog	0.010
Prosap	CG30483 gene product from transcript CG30483-RA	0.010
CG7813	CG7813 gene product from transcript CG7813-RA	0.010
snz	snazarus	0.010
Tsp42Ef	Tetraspanin 42Ef	0.010
obst-A	obstructor-A	0.010
debcl	death executioner Bcl-2 homologue	0.010
pr-set7	CG3307 gene product from transcript CG3307-RC	0.010
CG30421	CG30421 gene product from transcript CG30421-RA	0.010
Hsp68	Heat shock protein 68	0.010
Spt5	CG7626 gene product from transcript CG7626-RA	0.010
Utx	CG5640 gene product from transcript CG5640-RD	0.010
Cat	Catalase	0.010
CG11727	CG11727 gene product from transcript CG11727-RD	0.010
mub	mushroom-body expressed	0.010
CG31689	CG31689 gene product from transcript CG31689-RC	0.010
Paip2	polyA-binding protein interacting protein 2	0.010
conv	convoluted	0.010