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Drosophila melanogaster

20 genes annotated in fly

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zymogen activation

GO:0031638

The proteolytic processing of an inactive enzyme to an active form.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "zymogen activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "zymogen activation" (in gray)

Name	Description	Probability	Func Analog Organism
imd	immune deficiency	0.567
th	thread	0.508
Dredd	Death related ced-3/Nedd2-like protein	0.341
CG9772	CG9772 gene product from transcript CG9772-RB	0.294
egr	eiger	0.291	Human Mouse
Pli	Pellino	0.273
PGRP-LC	Peptidoglycan recognition protein LC	0.252
CG4030	CG4030 gene product from transcript CG4030-RA	0.248
Mcm3	Minichromosome maintenance 3	0.242
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.201
Spn28D	Serpin 28D	0.186
Spn27A	Serpin 27A	0.165
PGRP-SA	Peptidoglycan recognition protein SA	0.152
Cyt-c-d	Cytochrome c distal	0.147
Nc	Nedd2-like caspase	0.137
grim	CG4345 gene product from transcript CG4345-RA	0.125
CG5731	CG5731 gene product from transcript CG5731-RA	0.122
Df31	Decondensation factor 31	0.116
Ark	Apaf-1-related-killer	0.112
Sra-1	specifically Rac1-associated protein 1	0.112	Human
CG6361	CG6361 gene product from transcript CG6361-RA	0.107
Sox14	Sox box protein 14	0.103
Dcp-1	Death caspase-1	0.102	Fly
Trip1	CG8882 gene product from transcript CG8882-RA	0.090
CG13597	CG13597 gene product from transcript CG13597-RA	0.087
CG6426	CG6426 gene product from transcript CG6426-RA	0.083
Mst77F	Male-specific transcript 77F	0.082
nec	necrotic	0.079
CG12766	CG12766 gene product from transcript CG12766-RA	0.078
Fhos	CG42610 gene product from transcript CG42610-RC	0.076
slow	slowdown	0.076
Sp7	Serine protease 7	0.072	Fly
Mcm7	Minichromosome maintenance 7	0.071
XNP	CG4548 gene product from transcript CG4548-RA	0.066
CG9691	CG9691 gene product from transcript CG9691-RB	0.065
Spn1	Serine protease inhibitor 1	0.064
Pkd2	Polycystic kidney disease gene-2	0.063
ird5	immune response deficient 5	0.061
jar	jaguar	0.058
Idgf2	Imaginal disc growth factor 2	0.058
CG5146	CG5146 gene product from transcript CG5146-RA	0.057
RnrL	Ribonucleoside diphosphate reductase large subunit	0.055
cathD	CG1548 gene product from transcript CG1548-RA	0.053
wts	warts	0.052
gsb	gooseberry	0.049
msl-1	male-specific lethal 1	0.049
lea	leak	0.048	Human
eIF3-S8	CG4954 gene product from transcript CG4954-RA	0.048
dre4	CG1828 gene product from transcript CG1828-RB	0.048
HtrA2	CG8464 gene product from transcript CG8464-RA	0.047
Acp62F	Accessory gland peptide 62F	0.045
alphaTub84D	alpha-Tubulin at 84D	0.044
spz	spatzle	0.044
PGRP-SD	CG7496 gene product from transcript CG7496-RA	0.043
CG8600	CG8600 gene product from transcript CG8600-RB	0.043
Pvf2	PDGF- and VEGF-related factor 2	0.041
CG34110	CG34110 gene product from transcript CG34110-RC	0.041
CG9372	CG9372 gene product from transcript CG9372-RA	0.040
Obp56d	Odorant-binding protein 56d	0.040
CG14213	CG14213 gene product from transcript CG14213-RB	0.036
Uba2	Smt3 activating enzyme 2	0.034
yuri	yuri gagarin	0.034
east	enhanced adult sensory threshold	0.033
Art4	Arginine methyltransferase 4	0.033
lmg	lemming	0.033
CG15917	CG15917 gene product from transcript CG15917-RA	0.032
Acp53C14a	CG8626 gene product from transcript CG8626-RA	0.032
trio	CG18214 gene product from transcript CG18214-RA	0.031
shark	Src homology 2, ankyrin repeat, tyrosine kinase	0.031
ome	omega	0.031
Lsp2	Larval serum protein 2	0.030
Traf4	TNF-receptor-associated factor 4	0.030
CG5902	CG5902 gene product from transcript CG5902-RB	0.030
5-HT7	Serotonin receptor 7	0.030
nullo	CG14426 gene product from transcript CG14426-RB	0.030
CG18258	CG18258 gene product from transcript CG18258-RA	0.030
Aats-gly	Glycyl-tRNA synthetase	0.029
Fer2LCH	Ferritin 2 light chain homologue	0.029
Duox	Dual oxidase	0.029
alphaTub85E	alpha-Tubulin at 85E	0.028
vig	vasa intronic gene	0.028
EndoG	Endonuclease G	0.028
Bub1	Bub1 homologue	0.028
sw	short wing	0.028
Fmr1	CG6203 gene product from transcript CG6203-RC	0.028
Atg8a	Autophagy-specific gene 8a	0.028
RpL39	Ribosomal protein L39	0.028
Acp53C14b	CG15616 gene product from transcript CG15616-RA	0.027
Mnt	CG13316 gene product from transcript CG13316-RD	0.027
Nup75	Nucleoporin 75	0.026
l(2)05510	lethal (2) 05510	0.026
msopa	male-specific opa containing gene	0.026
nocte	no circadian temperature entrainment	0.026
Rbp1	RNA-binding protein 1	0.025
BG642163	CG34102 gene product from transcript CG34102-RA	0.025
enok	enoki mushroom	0.025
vvl	ventral veins lacking	0.025
iHog	interference Hedgehog	0.025
yellow-c	CG4182 gene product from transcript CG4182-RA	0.025
Mekk1	CG7717 gene product from transcript CG7717-RB	0.023
SmB	Small ribonucleoprotein particle protein SmB	0.023
wun2	wunen-2	0.023
CG3680	CG3680 gene product from transcript CG3680-RA	0.023
Myd88	CG2078 gene product from transcript CG2078-RA	0.023
CG8586	CG8586 gene product from transcript CG8586-RA	0.023
Lip3	CG8823 gene product from transcript CG8823-RA	0.022
BBS1	CG14825 gene product from transcript CG14825-RA	0.021
CG12029	CG12029 gene product from transcript CG12029-RB	0.021
CG1103	CG1103 gene product from transcript CG1103-RA	0.021
GNBP1	Gram-negative bacteria binding protein 1	0.021
vari	varicose	0.021
lute	CG5319 gene product from transcript CG5319-RA	0.021
lok	loki	0.021
CG34113	CG34113 gene product from transcript CG34113-RP	0.021
Gmd	GDP-mannose 4,6-dehydratase	0.021
betaTub56D	beta-Tubulin at 56D	0.021
CG6412	CG6412 gene product from transcript CG6412-RA	0.020
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.020
TepII	Thiolester containing protein II	0.020
fon	fondue	0.020
CG3239	CG3239 gene product from transcript CG3239-RB	0.020
Sema-1b	CG6446 gene product from transcript CG6446-RA	0.020
CG31326	CG31326 gene product from transcript CG31326-RA	0.020
sli	slit	0.019
Roc1b	CG16988 gene product from transcript CG16988-RA	0.019
CG7077	CG7077 gene product from transcript CG7077-RA	0.019
soti	scotti	0.019
CG5390	CG5390 gene product from transcript CG5390-RA	0.019
Src42A	Src oncogene at 42A	0.019
Atg1	Autophagy-specific gene 1	0.019
Cchl	Cytochrome c heme lyase	0.019
Osbp	Oxysterol binding protein	0.019
kl-5	male fertility factor kl5	0.019
CG14985	CG14985 gene product from transcript CG14985-RB	0.019
Nup160	Nucleoporin 160	0.019
CG10217	CG10217 gene product from transcript CG10217-RB	0.018
AGO2	Argonaute 2	0.018
Bsg25D	Blastoderm-specific gene 25D	0.018
DNaseII	Deoxyribonuclease II	0.018
CG5355	CG5355 gene product from transcript CG5355-RA	0.018
CG4318	CG4318 gene product from transcript CG4318-RB	0.018
IM10	Immune induced molecule 10	0.018
CG15800	CG15800 gene product from transcript CG15800-RA	0.018
BG4	CG12297 gene product from transcript CG12297-RA	0.018
Gclm	Glutamate-cysteine ligase modifier subunit	0.018
CG14567	CG14567 gene product from transcript CG14567-RA	0.017
Sgs1	Salivary gland secretion 1	0.017
comm	commissureless	0.017
WRNexo	WRN exonuclease	0.017
Cys	Cystatin-like	0.017
oys	oysgedart	0.017
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.017
mus201	mutagen-sensitive 201	0.016
GckIII	Germinal centre kinase III	0.016
E23	Early gene at 23	0.016
CG11842	CG11842 gene product from transcript CG11842-RA	0.016
eg	eagle	0.016
CG10026	CG10026 gene product from transcript CG10026-RA	0.016
CG7033	CG7033 gene product from transcript CG7033-RC	0.016
fd19B	forkhead domain 19B	0.016
CG10680	CG10680 gene product from transcript CG10680-RA	0.016
CG17362	CG17362 gene product from transcript CG17362-RA	0.016
CG12558	CG12558 gene product from transcript CG12558-RA	0.016
timeout	CG7855 gene product from transcript CG7855-RA	0.016
CG5273	CG5273 gene product from transcript CG5273-RA	0.016
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.016
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.016
CG18067	CG18067 gene product from transcript CG18067-RA	0.016
caz	cabeza	0.016
Ets65A	Ets at 65A	0.015
kto	kohtalo	0.015
His3.3B	Histone H3.3B	0.015
CG2469	CG2469 gene product from transcript CG2469-RB	0.015
CG12263	CG12263 gene product from transcript CG12263-RA	0.015
CG9821	CG9821 gene product from transcript CG9821-RB	0.015
GNBP3	Gram-negative bacteria binding protein 3	0.015
CG9134	CG9134 gene product from transcript CG9134-RB	0.015
CG16713	CG16713 gene product from transcript CG16713-RA	0.015
CG14526	CG14526 gene product from transcript CG14526-RB	0.015
RASSF8	CG5053 gene product from transcript CG5053-RA	0.015
a5	antennal protein 5	0.015
ZIP1	Zinc/iron regulated transporter-related protein 1	0.015
CG7564	CG7564 gene product from transcript CG7564-RA	0.015
CG2111	CG2111 gene product from transcript CG2111-RA	0.015
CG31199	CG31199 gene product from transcript CG31199-RA	0.014
CG31659	CG31659 gene product from transcript CG31659-RA	0.014
lectin-30A	CG17011 gene product from transcript CG17011-RA	0.014
Acp32CD	Accessory gland-specific peptide 32CD	0.014
CG10912	CG10912 gene product from transcript CG10912-RA	0.014
CG12990	CG12990 gene product from transcript CG12990-RA	0.014
CG32354	CG32354 gene product from transcript CG32354-RA	0.014
Hsp60D	CG16954 gene product from transcript CG16954-RA	0.014
key	kenny	0.014
CG14491	CG14491 gene product from transcript CG14491-RA	0.014
CG8784	CG8784 gene product from transcript CG8784-RA	0.014
CG5909	CG5909 gene product from transcript CG5909-RA	0.014	Fly
Spn77Bc	Serpin 77Bc	0.014
RpL7-like	Ribosomal protein L7-like	0.014
mad2	CG17498 gene product from transcript CG17498-RA	0.014
Yp3	Yolk protein 3	0.014
Acp70A	Accessory gland peptide 70A	0.014
Ef1alpha48D	Elongation factor 1alpha48D	0.014
DNApol-alpha60	DNA polymerase alpha 60kD	0.014
alphaTub84B	alpha-Tubulin at 84B	0.014
p53	CG33336 gene product from transcript CG33336-RB	0.014
CG13962	CG13962 gene product from transcript CG13962-RA	0.014
CDC45L	CG3658 gene product from transcript CG3658-RA	0.014
CG5267	CG5267 gene product from transcript CG5267-RA	0.014
Ice	CG7788 gene product from transcript CG7788-RA	0.014	Fly
CG9812	CG9812 gene product from transcript CG9812-RB	0.014
CG5270	CG5270 gene product from transcript CG5270-RB	0.013
CG32833	CG32833 gene product from transcript CG32833-RA	0.013
CG32412	CG32412 gene product from transcript CG32412-RA	0.013
pyr	pyramus	0.013
psh	persephone	0.013
CG10630	CG10630 gene product from transcript CG10630-RA	0.013
spag4	sperm-associated antigen 4	0.013
Vinc	Vinculin	0.013
CG7320	CG7320 gene product from transcript CG7320-RA	0.013
CG16721	CG16721 gene product from transcript CG16721-RA	0.013
opa1-like	optic atrophy 1-like	0.013
CG7998	CG7998 gene product from transcript CG7998-RA	0.013
CG15641	CG15641 gene product from transcript CG15641-RA	0.013
CG1701	CG1701 gene product from transcript CG1701-RB	0.013
nimB4	nimrod B4	0.013
CG6966	CG6966 gene product from transcript CG6966-RB	0.013
SPE	Spatzle-Processing Enzyme	0.013
CG5791	CG5791 gene product from transcript CG5791-RA	0.013
CG15828	CG15828 gene product from transcript CG15828-RC	0.013
drpr	draper	0.012
Trc8	CG2304 gene product from transcript CG2304-RB	0.012
Tig	Tiggrin	0.012
CG9114	CG9114 gene product from transcript CG9114-RA	0.012
RpL8	Ribosomal protein L8	0.012
nerfin-1	nervous fingers 1	0.012
l(2)08717	lethal (2) 08717	0.012
CG18347	CG18347 gene product from transcript CG18347-RA	0.012
CG14061	CG14061 gene product from transcript CG14061-RA	0.012
CG5783	CG5783 gene product from transcript CG5783-RA	0.012
CG16772	CG16772 gene product from transcript CG16772-RA	0.012
cindr	CIN85 and CD2AP orthologue	0.012
Mst57Dc	Male-specific RNA 57Dc	0.012
Dhod	Dihydroorotate dehydrogenase	0.012
CG4747	CG4747 gene product from transcript CG4747-RB	0.012
pr-set7	CG3307 gene product from transcript CG3307-RC	0.012
CG18480	CG18480 gene product from transcript CG18480-RA	0.012
Arp5	Actin-related protein 5	0.012
Gr66a	Gustatory receptor 66a	0.012
Rbp6	RNA-binding protein 6	0.012
Or92a	Odorant receptor 92a	0.012
Mct1	Monocarboxylate transporter 1	0.012
Cks85A	Cyclin-dependent kinase subunit 85A	0.012
scrib	scribbled	0.012
Gef26	CG9491 gene product from transcript CG9491-RB	0.012
snk	snake	0.012
CG9631	CG9631 gene product from transcript CG9631-RA	0.012
CG5366	CG5366 gene product from transcript CG5366-RA	0.012
CG13759	CG13759 gene product from transcript CG13759-RB	0.012
CG12025	CG12025 gene product from transcript CG12025-RA	0.012
mtRNApol	mitochondrial RNA polymerase	0.012
CG3530	CG3530 gene product from transcript CG3530-RC	0.012
Glut1	Glucose transporter 1	0.012
CG5155	CG5155 gene product from transcript CG5155-RA	0.012
comr	cookie monster	0.012
skpB	CG8881 gene product from transcript CG8881-RA	0.011
RpL22	Ribosomal protein L22	0.011
Cpr5C	Cuticular protein 5C	0.011
Wnt6	CG4969 gene product from transcript CG4969-RB	0.011
CG14880	CG14880 gene product from transcript CG14880-RA	0.011
CG13579	CG13579 gene product from transcript CG13579-RA	0.011
Spn77Bb	Serpin 77Bb	0.011
CG8801	CG8801 gene product from transcript CG8801-RA	0.011
CG5262	CG5262 gene product from transcript CG5262-RA	0.011
cln3	CG5582 gene product from transcript CG5582-RA	0.011
CG10029	CG10029 gene product from transcript CG10029-RA	0.011
CG18735	CG18735 gene product from transcript CG18735-RA	0.011
CG42588	CG42588 gene product from transcript CG42588-RA	0.011
Muc91C	Mucin 91C	0.011
CG3916	CG3916 gene product from transcript CG3916-RA	0.011
pzg	putzig	0.011
kl-3	male fertility factor kl3	0.011
CG32199	CG32199 gene product from transcript CG32199-RA	0.011
CG13679	CG13679 gene product from transcript CG13679-RA	0.011
CG5778	CG5778 gene product from transcript CG5778-RB	0.011
edl	ETS-domain lacking	0.011
dve	defective proventriculus	0.011
flower	CG6151 gene product from transcript CG6151-RA	0.011
CG18673	CG18673 gene product from transcript CG18673-RB	0.011
CG5162	CG5162 gene product from transcript CG5162-RA	0.011
CG31029	CG31029 gene product from transcript CG31029-RA	0.011
Obp8a	Odorant-binding protein 8a	0.011
CG17264	CG17264 gene product from transcript CG17264-RA	0.011
CG6688	CG6688 gene product from transcript CG6688-RA	0.010
CG12753	CG12753 gene product from transcript CG12753-RB	0.010
CG9247	CG9247 gene product from transcript CG9247-RA	0.010
Cht2	Chitinase 2	0.010
CG6675	CG6675 gene product from transcript CG6675-RB	0.010
CG18231	CG18231 gene product from transcript CG18231-RB	0.010
Eip74EF	Ecdysone-induced protein 74EF	0.010
Reps	CG6192 gene product from transcript CG6192-RA	0.010
CG4036	CG4036 gene product from transcript CG4036-RC	0.010
CG2962	CG2962 gene product from transcript CG2962-RA	0.010
spirit	Serine Protease Immune Response Integrator	0.010
CG10586	CG10586 gene product from transcript CG10586-RA	0.010
Rab30	CG9100 gene product from transcript CG9100-RB	0.010
CG9986	CG9986 gene product from transcript CG9986-RA	0.010
CG3483	CG3483 gene product from transcript CG3483-RA	0.010
rno	rhinoceros	0.010
CG13117	CG13117 gene product from transcript CG13117-RA	0.010
CG14455	CG14455 gene product from transcript CG14455-RA	0.010
osm-6	CG9595 gene product from transcript CG9595-RA	0.010
CG7630	CG7630 gene product from transcript CG7630-RA	0.010
fan	farinelli	0.010
CG18302	CG18302 gene product from transcript CG18302-RA	0.010
IM2	Immune induced molecule 2	0.010
dik	diskette	0.010
CG14111	CG14111 gene product from transcript CG14111-RA	0.010