IMP

Process View

Homo sapiens

32 genes annotated in human

cellular response to uv

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to uv"

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Name	Description	Probability	Func Analog Organism
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.985
BCL2	B-cell CLL/lymphoma 2	0.964
TEK	TEK tyrosine kinase, endothelial	0.934
HIST1H3D	histone cluster 1, H3d	0.932	Human
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.845	Human
DDB1	damage-specific DNA binding protein 1, 127kDa	0.844
HIST1H2BG	histone cluster 1, H2bg	0.784
INO80	INO80 homolog (S. cerevisiae)	0.773
HIST2H2BE	histone cluster 2, H2be	0.728
RUVBL1	RuvB-like 1 (E. coli)	0.719
HIST1H2AE	histone cluster 1, H2ae	0.650	Human
BCL2L1	BCL2-like 1	0.613	Human
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.593
HIST1H1C	histone cluster 1, H1c	0.556
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.537
HIST1H2BE	histone cluster 1, H2be	0.519
BAD	BCL2-associated agonist of cell death	0.518
XIAP	X-linked inhibitor of apoptosis	0.512
BAX	BCL2-associated X protein	0.450	Human Mouse
APAF1	apoptotic peptidase activating factor 1	0.443
HIST1H2AI	histone cluster 1, H2ai	0.432	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.390
HIST1H2BK	histone cluster 1, H2bk	0.386
CCNE1	cyclin E1	0.357
IRAK2	interleukin-1 receptor-associated kinase 2	0.350
HIST1H2AJ	histone cluster 1, H2aj	0.349	Human
YY1	YY1 transcription factor	0.344
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	0.324
HIST1H2BC	histone cluster 1, H2bc	0.314
HIST1H2BD	histone cluster 1, H2bd	0.304
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.232
NLRC4	NLR family, CARD domain containing 4	0.197
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.194
CLSPN	claspin	0.194
HIST1H4H	histone cluster 1, H4h	0.188
RB1	retinoblastoma 1	0.186
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.178
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.178
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.174	Human
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.168
FGA	fibrinogen alpha chain	0.163
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.160
CUL4A	cullin 4A	0.145	Human
HIST1H2AM	histone cluster 1, H2am	0.136
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.133	Human Yeast
HIST1H3A	histone cluster 1, H3a	0.119
CUL1	cullin 1	0.114
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.113
MAP2K4	mitogen-activated protein kinase kinase 4	0.113
HIST1H3H	histone cluster 1, H3h	0.113
BIRC5	baculoviral IAP repeat containing 5	0.110
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.109	Human
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.106
HIST2H2AA4	histone cluster 2, H2aa4	0.105	Human
FAS	Fas (TNF receptor superfamily, member 6)	0.104
VPRBP	Vpr (HIV-1) binding protein	0.104
INO80E	INO80 complex subunit E	0.101
ACTR5	ARP5 actin-related protein 5 homolog (yeast)	0.097
TP53	tumor protein p53	0.097	Mouse
HIST1H2BJ	histone cluster 1, H2bj	0.093
HIST1H2BI	histone cluster 1, H2bi	0.088
BID	BH3 interacting domain death agonist	0.079
RFWD2	ring finger and WD repeat domain 2	0.079
ARRB1	arrestin, beta 1	0.072
HIST1H2AC	histone cluster 1, H2ac	0.063	Human
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.063
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.063
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.060	Human
BAK1	BCL2-antagonist/killer 1	0.060
FADD	Fas (TNFRSF6)-associated via death domain	0.060
CDK2	cyclin-dependent kinase 2	0.058
FGG	fibrinogen gamma chain	0.057
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.054	Human
HIST1H2BF	histone cluster 1, H2bf	0.053
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.052
HIST1H4D	histone cluster 1, H4d	0.052
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.051	Human
MAX	MYC associated factor X	0.050
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.049
RIPK2	receptor-interacting serine-threonine kinase 2	0.048
HIST1H2AB	histone cluster 1, H2ab	0.047	Human
DLG1	discs, large homolog 1 (Drosophila)	0.047
FOXM1	forkhead box M1	0.047
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.045
BIRC2	baculoviral IAP repeat containing 2	0.045
HIST1H2BM	histone cluster 1, H2bm	0.045
HIST1H2AK	histone cluster 1, H2ak	0.044	Human
ANGPT2	angiopoietin 2	0.044	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.042
KIAA1377	KIAA1377	0.042
XPC	xeroderma pigmentosum, complementation group C	0.042
FBXL15	F-box and leucine-rich repeat protein 15	0.041
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.041
BTRC	beta-transducin repeat containing	0.040
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.040
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.039
HUWE1	HECT, UBA and WWE domain containing 1	0.038
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.038
BRCA1	breast cancer 1, early onset	0.037
ZFYVE9	zinc finger, FYVE domain containing 9	0.036
HIST1H2BO	histone cluster 1, H2bo	0.035
TRAF6	TNF receptor-associated factor 6	0.035
HIST2H4A	histone cluster 2, H4a	0.035
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.035
HIST1H4B	histone cluster 1, H4b	0.033
FASLG	Fas ligand (TNF superfamily, member 6)	0.032
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.032
KCTD17	potassium channel tetramerisation domain containing 17	0.032
E2F1	E2F transcription factor 1	0.031
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.031
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.031
RHOA	ras homolog gene family, member A	0.030
SPRY2	sprouty homolog 2 (Drosophila)	0.030
HIST1H2AL	histone cluster 1, H2al	0.030	Human
SMAD4	SMAD family member 4	0.030
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.029	Human Yeast
CCDC6	coiled-coil domain containing 6	0.028
HIST1H3B	histone cluster 1, H3b	0.028
USP15	ubiquitin specific peptidase 15	0.028
DDIT4	DNA-damage-inducible transcript 4	0.028
LRDD	leucine-rich repeats and death domain containing	0.027
DDB2	damage-specific DNA binding protein 2, 48kDa	0.026
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.026
HIST1H2BB	histone cluster 1, H2bb	0.026
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.025
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.025
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.024	Human Yeast
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.024
HIST1H2AG	histone cluster 1, H2ag	0.024	Human
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.023
MAPK8	mitogen-activated protein kinase 8	0.023
HIST1H4E	histone cluster 1, H4e	0.023
YAF2	YY1 associated factor 2	0.023
TRIM37	tripartite motif containing 37	0.023
C4orf14	chromosome 4 open reading frame 14	0.023
ACTL6A	actin-like 6A	0.023
HIST2H2AA3	histone cluster 2, H2aa3	0.023	Human
CXXC5	CXXC finger protein 5	0.023
IRS1	insulin receptor substrate 1	0.022
DBN1	drebrin 1	0.022
RNR2	l-rRNA	0.022
NOTCH1	notch 1	0.022
HIST1H3G	histone cluster 1, H3g	0.022
ANGPT1	angiopoietin 1	0.022	Human
AMBRA1	autophagy/beclin-1 regulator 1	0.022
MAGED1	melanoma antigen family D, 1	0.022
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.022
HIST1H4A	histone cluster 1, H4a	0.022	Human
HSPA4	heat shock 70kDa protein 4	0.022
BIK	BCL2-interacting killer (apoptosis-inducing)	0.021
WEE1	WEE1 homolog (S. pombe)	0.021
WRN	Werner syndrome, RecQ helicase-like	0.021
RNF144B	ring finger protein 144B	0.021
DIABLO	diablo, IAP-binding mitochondrial protein	0.021
VDAC1	voltage-dependent anion channel 1	0.021
CCNB2	cyclin B2	0.021
BRD7	bromodomain containing 7	0.021
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.020
CRIP2	cysteine-rich protein 2	0.020	Human
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.020
XPO7	exportin 7	0.020
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.020
TRIP6	thyroid hormone receptor interactor 6	0.019
H2AFX	H2A histone family, member X	0.019	Human
INCENP	inner centromere protein antigens 135/155kDa	0.019
TIMELESS	timeless homolog (Drosophila)	0.019
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.019
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.019
USP28	ubiquitin specific peptidase 28	0.018
ACTR8	ARP8 actin-related protein 8 homolog (yeast)	0.018
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.018
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.018	Human Yeast
PLCG1	phospholipase C, gamma 1	0.018
CAV1	caveolin 1, caveolae protein, 22kDa	0.018
FBXW11	F-box and WD repeat domain containing 11	0.018
HIST1H4I	histone cluster 1, H4i	0.018
ING2	inhibitor of growth family, member 2	0.017
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.017
ADAMTSL4	ADAMTS-like 4	0.017
UIMC1	ubiquitin interaction motif containing 1	0.017
PTEN	phosphatase and tensin homolog	0.017
MYO6	myosin VI	0.017
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.017	Human Yeast
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.017	Human
ACTB	actin, beta	0.017
APTX	aprataxin	0.017
HIST2H2AC	histone cluster 2, H2ac	0.016	Human
HSPA8	heat shock 70kDa protein 8	0.016
ADARB1	adenosine deaminase, RNA-specific, B1	0.016
ARRB2	arrestin, beta 2	0.016
RAI1	retinoic acid induced 1	0.016
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.015
RNF168	ring finger protein 168	0.015
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.015
WDR5	WD repeat domain 5	0.015
NFRKB	nuclear factor related to kappaB binding protein	0.015
TUBB8	tubulin, beta 8	0.015
XPA	xeroderma pigmentosum, complementation group A	0.015
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.015
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.015
CWC15	CWC15 spliceosome-associated protein homolog (S. cerevisiae)	0.015
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.015
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.014
HIST2H4B	histone cluster 2, H4b	0.014
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.014
JUN	jun proto-oncogene	0.014
ANKRD13A	ankyrin repeat domain 13A	0.014
HIST1H1D	histone cluster 1, H1d	0.014
EP300	E1A binding protein p300	0.014
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.014
SFN	stratifin	0.014
ATM	ataxia telangiectasia mutated	0.014
TP53BP2	tumor protein p53 binding protein, 2	0.014
CD34	CD34 molecule	0.014
ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.014
PYCARD	PYD and CARD domain containing	0.014
HIST1H4J	histone cluster 1, H4j	0.014
WNK1	WNK lysine deficient protein kinase 1	0.014
UBQLN2	ubiquilin 2	0.014
FKBP4	FK506 binding protein 4, 59kDa	0.013
CCDC127	coiled-coil domain containing 127	0.013
USP25	ubiquitin specific peptidase 25	0.013	Human
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.013
YAP1	Yes-associated protein 1	0.013
CARD16	caspase recruitment domain family, member 16	0.013
HIST1H4L	histone cluster 1, H4l	0.013
NMI	N-myc (and STAT) interactor	0.013
LAMA4	laminin, alpha 4	0.013
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.013
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.013
SIRT1	sirtuin 1	0.013
DCAF11	DDB1 and CUL4 associated factor 11	0.013
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.013
KIAA1712	KIAA1712	0.013
IFI16	interferon, gamma-inducible protein 16	0.013
GBP2	guanylate binding protein 2, interferon-inducible	0.012
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.012
ING1	inhibitor of growth family, member 1	0.012
HIST1H2BN	histone cluster 1, H2bn	0.012
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.012
PTPRB	protein tyrosine phosphatase, receptor type, B	0.012
FDXR	ferredoxin reductase	0.012
HSPH1	heat shock 105kDa/110kDa protein 1	0.012
IRAK1	interleukin-1 receptor-associated kinase 1	0.012
CDK6	cyclin-dependent kinase 6	0.012
CXCL2	chemokine (C-X-C motif) ligand 2	0.011
MYOD1	myogenic differentiation 1	0.011
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.011
BMI1	BMI1 polycomb ring finger oncogene	0.011
ZNF512B	zinc finger protein 512B	0.011
GRB7	growth factor receptor-bound protein 7	0.011
ZRANB1	zinc finger, RAN-binding domain containing 1	0.011
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.011
TOLLIP	toll interacting protein	0.011
RYBP	RING1 and YY1 binding protein	0.011
TMSB4X	thymosin beta 4, X-linked	0.011
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.011
DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	0.011
UBASH3B	ubiquitin associated and SH3 domain containing B	0.011
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.011
TONSL	tonsoku-like, DNA repair protein	0.011
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.011
MARK3	MAP/microtubule affinity-regulating kinase 3	0.011
CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	0.011
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.011
EEF2K	eukaryotic elongation factor-2 kinase	0.011
MYD88	myeloid differentiation primary response gene (88)	0.011
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.011
SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.011
RAD50	RAD50 homolog (S. cerevisiae)	0.010
ARRDC3	arrestin domain containing 3	0.010
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.010
ATN1	atrophin 1	0.010
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	0.010
CDT1	chromatin licensing and DNA replication factor 1	0.010
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.010
PRKCDBP	protein kinase C, delta binding protein	0.010
TUBB2A	tubulin, beta 2A	0.010
HIST3H2A	histone cluster 3, H2a	0.010
GRB10	growth factor receptor-bound protein 10	0.010
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.010
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.010
PTPRD	protein tyrosine phosphatase, receptor type, D	0.010	Human
AEN	apoptosis enhancing nuclease	0.010
CRIP1	cysteine-rich protein 1 (intestinal)	0.010
POU5F1	POU class 5 homeobox 1	0.010