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Homo sapiens

27 genes annotated in human

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regulation of jun kinase activity

GO:0043506

Any process that modulates the frequency, rate or extent of JUN kinase activity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of jun kinase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of jun kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
ZNF43	zinc finger protein 43	0.991
TRAF6	TNF receptor-associated factor 6	0.984
TRAF2	TNF receptor-associated factor 2	0.983
CSNK1E	casein kinase 1, epsilon	0.980
MAPK8	mitogen-activated protein kinase 8	0.958	Fly
TRAF1	TNF receptor-associated factor 1	0.955	Human
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.942
BBS10	Bardet-Biedl syndrome 10	0.908
IL1R1	interleukin 1 receptor, type I	0.883
ZNF273	zinc finger protein 273	0.860	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.851
ZNF253	zinc finger protein 253	0.840
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.811
TRADD	TNFRSF1A-associated via death domain	0.778
ZNF675	zinc finger protein 675	0.761
MAP2K4	mitogen-activated protein kinase kinase 4	0.757	Zebrafish Rat Fly
ARRB1	arrestin, beta 1	0.724
TRAF5	TNF receptor-associated factor 5	0.703	Human
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.646	Human
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.644
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.511	Mouse Rat
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.506
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.494
IRAK2	interleukin-1 receptor-associated kinase 2	0.427
ZNF85	zinc finger protein 85	0.415	Human
MAP2K7	mitogen-activated protein kinase kinase 7	0.381	Mouse Rat Worm Fly
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.363	Rat
ZMYND11	zinc finger, MYND-type containing 11	0.356
AXIN1	axin 1	0.343	Zebrafish Mouse
ZNF117	zinc finger protein 117	0.323	Human
SMAD2	SMAD family member 2	0.309
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.296
TICAM2	toll-like receptor adaptor molecule 2	0.250
CD40	CD40 molecule, TNF receptor superfamily member 5	0.240	Human
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.219
ZNF93	zinc finger protein 93	0.217
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.205	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.200
ZNF91	zinc finger protein 91	0.192
EGFR	epidermal growth factor receptor	0.170
LRP6	low density lipoprotein receptor-related protein 6	0.166
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.163
TRAF3	TNF receptor-associated factor 3	0.158	Human
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.151
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.148	Human
FZD1	frizzled homolog 1 (Drosophila)	0.144	Human
SH3KBP1	SH3-domain kinase binding protein 1	0.139
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.138
ZNF254	zinc finger protein 254	0.138	Human
MYD88	myeloid differentiation primary response gene (88)	0.137
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.136
JUN	jun proto-oncogene	0.129
ARL4D	ADP-ribosylation factor-like 4D	0.126
PTK2	PTK2 protein tyrosine kinase 2	0.124
PELI3	pellino homolog 3 (Drosophila)	0.120
MAPK9	mitogen-activated protein kinase 9	0.120	Fly
BLNK	B-cell linker	0.118
ZNF512B	zinc finger protein 512B	0.116
LRRK2	leucine-rich repeat kinase 2	0.108
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.104
PTEN	phosphatase and tensin homolog	0.101
TIFA	TRAF-interacting protein with forkhead-associated domain	0.099
CAV1	caveolin 1, caveolae protein, 22kDa	0.098
ZNF708	zinc finger protein 708	0.084	Human
ZNF430	zinc finger protein 430	0.081	Human
OCLN	occludin	0.074
LAT	linker for activation of T cells	0.073
ZNF107	zinc finger protein 107	0.069
IL1RAP	interleukin 1 receptor accessory protein	0.068
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.067
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.067
S100B	S100 calcium binding protein B	0.059
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.055
BIRC3	baculoviral IAP repeat containing 3	0.053
VAV1	vav 1 guanine nucleotide exchange factor	0.053
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.053
WT1	Wilms tumor 1	0.050
SMAD3	SMAD family member 3	0.050
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.049
TNK2	tyrosine kinase, non-receptor, 2	0.048
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.047	Human
SH3RF1	SH3 domain containing ring finger 1	0.045
BTK	Bruton agammaglobulinemia tyrosine kinase	0.045
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.045
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.044
IRAK3	interleukin-1 receptor-associated kinase 3	0.044
ZNF680	zinc finger protein 680	0.044	Human
BAI1	brain-specific angiogenesis inhibitor 1	0.043
MDFI	MyoD family inhibitor	0.043
SMAD7	SMAD family member 7	0.040
GRB2	growth factor receptor-bound protein 2	0.040
ZNF92	zinc finger protein 92	0.040	Human
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.040
TTR	transthyretin	0.038
ADRB2	adrenergic, beta-2-, receptor, surface	0.038
GSK3B	glycogen synthase kinase 3 beta	0.038	Fly
CADM4	cell adhesion molecule 4	0.037
FLNB	filamin B, beta	0.037
WWOX	WW domain containing oxidoreductase	0.036
RHOU	ras homolog gene family, member U	0.036
MYST2	MYST histone acetyltransferase 2	0.035
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.033
LIMD1	LIM domains containing 1	0.033
ELK1	ELK1, member of ETS oncogene family	0.032
STAT5A	signal transducer and activator of transcription 5A	0.032
TRAF3IP2	TRAF3 interacting protein 2	0.032
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.031
LY96	lymphocyte antigen 96	0.030
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.030
GAST	gastrin	0.029
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.029
ATXN3	ataxin 3	0.028
BCAR1	breast cancer anti-estrogen resistance 1	0.028
TOX4	TOX high mobility group box family member 4	0.028
ZNF682	zinc finger protein 682	0.027	Human
TNF	tumor necrosis factor	0.026
FRS2	fibroblast growth factor receptor substrate 2	0.026
TLR2	toll-like receptor 2	0.025
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.025
WNT5A	wingless-type MMTV integration site family, member 5A	0.025
ELF5	E74-like factor 5 (ets domain transcription factor)	0.025
IL1R2	interleukin 1 receptor, type II	0.024
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.024
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.024
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.024	Human
APP	amyloid beta (A4) precursor protein	0.024
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.023	Human
ZNF506	zinc finger protein 506	0.022	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.022
MCC	mutated in colorectal cancers	0.022
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	0.022
ARRB2	arrestin, beta 2	0.021
SOS2	son of sevenless homolog 2 (Drosophila)	0.021
CSNK1D	casein kinase 1, delta	0.021
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.021
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.021	Mouse
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.021
SIAH1	seven in absentia homolog 1 (Drosophila)	0.020
PNRC2	proline-rich nuclear receptor coactivator 2	0.020
CD33	CD33 molecule	0.020
ARHGAP5	Rho GTPase activating protein 5	0.020
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.020
EXOC5	exocyst complex component 5	0.020
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.019
C1orf93	chromosome 1 open reading frame 93	0.019
FAM110C	family with sequence similarity 110, member C	0.019
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.019
SMAD1	SMAD family member 1	0.018
WNT3A	wingless-type MMTV integration site family, member 3A	0.018	Human
ARF6	ADP-ribosylation factor 6	0.017
SH3BP2	SH3-domain binding protein 2	0.017
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.017
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.017
RIPK2	receptor-interacting serine-threonine kinase 2	0.017
PXN	paxillin	0.017
IRAK1	interleukin-1 receptor-associated kinase 1	0.017	Mouse
GSK3A	glycogen synthase kinase 3 alpha	0.016	Fly
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.016
ZNF136	zinc finger protein 136	0.016
ZNF195	zinc finger protein 195	0.016	Human
SLA	Src-like-adaptor	0.016
XIAP	X-linked inhibitor of apoptosis	0.016
SFRP1	secreted frizzled-related protein 1	0.016	Mouse
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.016
FRZB	frizzled-related protein	0.016	Human
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.016
PER1	period homolog 1 (Drosophila)	0.016
PTPRA	protein tyrosine phosphatase, receptor type, A	0.016
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.016
DLG4	discs, large homolog 4 (Drosophila)	0.015
PDCD6IP	programmed cell death 6 interacting protein	0.015
LMO4	LIM domain only 4	0.015
CYTH4	cytohesin 4	0.015
SKIL	SKI-like oncogene	0.015
GRAP2	GRB2-related adaptor protein 2	0.014
HES1	hairy and enhancer of split 1, (Drosophila)	0.014
CEP110	centrosomal protein 110kDa	0.014
TMOD3	tropomodulin 3 (ubiquitous)	0.014
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.014
HSPH1	heat shock 105kDa/110kDa protein 1	0.014
LIMK2	LIM domain kinase 2	0.014
MATK	megakaryocyte-associated tyrosine kinase	0.014
MAP2K6	mitogen-activated protein kinase kinase 6	0.014
NDP	Norrie disease (pseudoglioma)	0.014
GAB2	GRB2-associated binding protein 2	0.013
FAM110A	family with sequence similarity 110, member A	0.013
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.013
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.013
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.013
SOS1	son of sevenless homolog 1 (Drosophila)	0.013
MYO6	myosin VI	0.013
ZRANB1	zinc finger, RAN-binding domain containing 1	0.013
MTMR4	myotubularin related protein 4	0.013
CEP164	centrosomal protein 164kDa	0.012
ZNF100	zinc finger protein 100	0.012	Human
CREB1	cAMP responsive element binding protein 1	0.012
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.012
NUMBL	numb homolog (Drosophila)-like	0.012
RGS2	regulator of G-protein signaling 2, 24kDa	0.012
IL10RA	interleukin 10 receptor, alpha	0.012
NCF2	neutrophil cytosolic factor 2	0.012
MED28	mediator complex subunit 28	0.012
MAP2K3	mitogen-activated protein kinase kinase 3	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
LY86	lymphocyte antigen 86	0.012
ZNF665	zinc finger protein 665	0.012
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.012
PECAM1	platelet/endothelial cell adhesion molecule	0.011
ZNF320	zinc finger protein 320	0.011
MBD6	methyl-CpG binding domain protein 6	0.011
TRIP10	thyroid hormone receptor interactor 10	0.011
VAV3	vav 3 guanine nucleotide exchange factor	0.011
PILRA	paired immunoglobin-like type 2 receptor alpha	0.011
KCTD12	potassium channel tetramerisation domain containing 12	0.011
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.011
FBLN1	fibulin 1	0.011
ERN1	endoplasmic reticulum to nucleus signaling 1	0.011
YAP1	Yes-associated protein 1	0.011
RNASE6	ribonuclease, RNase A family, k6	0.011
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.011	Mouse
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.011
CD27	CD27 molecule	0.011
UNC119	unc-119 homolog (C. elegans)	0.011
BMPR1A	bone morphogenetic protein receptor, type IA	0.011
PLEK	pleckstrin	0.011
SH3RF3	SH3 domain containing ring finger 3	0.011
CCR7	chemokine (C-C motif) receptor 7	0.011
TLR1	toll-like receptor 1	0.011	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.010
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.010
UBASH3B	ubiquitin associated and SH3 domain containing B	0.010
PIAS2	protein inhibitor of activated STAT, 2	0.010
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.010
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.010
SQSTM1	sequestosome 1	0.010
SOCS1	suppressor of cytokine signaling 1	0.010
CPA3	carboxypeptidase A3 (mast cell)	0.010
MFAP4	microfibrillar-associated protein 4	0.010
RANBP9	RAN binding protein 9	0.010
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.010
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.010
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.010
ZC3H12A	zinc finger CCCH-type containing 12A	0.010
HIPK2	homeodomain interacting protein kinase 2	0.010
GADD45B	growth arrest and DNA-damage-inducible, beta	0.010
CCL22	chemokine (C-C motif) ligand 22	0.010