The network for 't cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

t cell proliferation

The expansion of a T cell population by cell division. Follows T cell activation.

Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 1.000
Ikzf1 IKAROS family zinc finger 1 0.997
Foxp3 forkhead box P3 0.995
Efnb2 ephrin B2 0.995
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.985
Il2 interleukin 2 0.984
Socs1 suppressor of cytokine signaling 1 0.979
Igh immunoglobulin heavy chain complex 0.979
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.975
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.974
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.973
Btk Bruton agammaglobulinemia tyrosine kinase 0.972
Cd40 CD40 antigen 0.971
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.968
Ccl2 chemokine (C-C motif) ligand 2 0.964
Foxn1 forkhead box N1 0.960
Cbl Casitas B-lineage lymphoma 0.958
Il4 interleukin 4 0.944
Stat3 signal transducer and activator of transcription 3 0.939
Cd4 CD4 antigen 0.933
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.931
Birc3 baculoviral IAP repeat-containing 3 0.926
Pdcd1 programmed cell death 1 0.921
Tnf tumor necrosis factor 0.919
Fas Fas (TNF receptor superfamily member 6) 0.911
Casp1 caspase 1 0.906
Cd80 CD80 antigen 0.900
Cd19 CD19 antigen 0.897
Ctnnb1 catenin (cadherin associated protein), beta 1 0.874
Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 0.867
Ank1 ankyrin 1, erythroid 0.865
Nckap1l NCK associated protein 1 like 0.865
Selp selectin, platelet 0.865
Fasl Fas ligand (TNF superfamily, member 6) 0.864
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.860
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.859
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.857
Dok1 docking protein 1 0.851
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.851
Lta lymphotoxin A 0.844
Icos inducible T-cell co-stimulator 0.839
Fgfr2 fibroblast growth factor receptor 2 0.836
Stat5b signal transducer and activator of transcription 5B 0.834
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.818
Il2rb interleukin 2 receptor, beta chain 0.816
Lyz2 lysozyme 2 0.813
Card11 caspase recruitment domain family, member 11 0.796
Cdk6 cyclin-dependent kinase 6 0.796
Clec4d C-type lectin domain family 4, member d 0.794
Was Wiskott-Aldrich syndrome homolog (human) 0.792
Stat1 signal transducer and activator of transcription 1 0.785
Grb2 growth factor receptor bound protein 2 0.780
Ret ret proto-oncogene 0.765
Il1b interleukin 1 beta 0.764
Cdk4 cyclin-dependent kinase 4 0.760
Cd3e CD3 antigen, epsilon polypeptide 0.756
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.755
Inpp5d inositol polyphosphate-5-phosphatase D 0.750
Nf1 neurofibromatosis 1 0.750
Casp8 caspase 8 0.747
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.747
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.743
Gli3 GLI-Kruppel family member GLI3 0.732
Emx1 empty spiracles homolog 1 (Drosophila) 0.728
Ltb lymphotoxin B 0.727
Kit kit oncogene 0.724
Itgb2 integrin beta 2 0.724
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.723
Rybp RING1 and YY1 binding protein 0.722
Traf6 TNF receptor-associated factor 6 0.717
Irf5 interferon regulatory factor 5 0.707
Nlrp3 NLR family, pyrin domain containing 3 0.702
Wnt3a wingless-related MMTV integration site 3A 0.701
Pten phosphatase and tensin homolog 0.695
Csf1 colony stimulating factor 1 (macrophage) 0.692
Spna1 spectrin alpha 1 0.688
Ccr7 chemokine (C-C motif) receptor 7 0.684
Ccr1 chemokine (C-C motif) receptor 1 0.682
Shh sonic hedgehog 0.682
Cd28 CD28 antigen 0.680
Cd86 CD86 antigen 0.665
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.665
Rag2 recombination activating gene 2 0.663
Ttc7 tetratricopeptide repeat domain 7 0.661
Bcl2 B-cell leukemia/lymphoma 2 0.660
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.651
Il12b interleukin 12b 0.647
Gpr132 G protein-coupled receptor 132 0.643
Ccnd1 cyclin D1 0.638
Lck lymphocyte protein tyrosine kinase 0.636
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.634
Prf1 perforin 1 (pore forming protein) 0.631
Jak2 Janus kinase 2 0.627
Ccl3 chemokine (C-C motif) ligand 3 0.626
Clec4n C-type lectin domain family 4, member n 0.625
Batf basic leucine zipper transcription factor, ATF-like 0.622
Ccl5 chemokine (C-C motif) ligand 5 0.622
Sh2d2a SH2 domain protein 2A 0.621
Dock2 dedicator of cyto-kinesis 2 0.621
Ephb2 Eph receptor B2 0.619
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HLA-DRA major histocompatibility complex, class II, DR alpha 0.967
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.932
CD80 CD80 molecule 0.930
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.926
BIRC3 baculoviral IAP repeat containing 3 0.882
SOCS3 suppressor of cytokine signaling 3 0.830
LCK lymphocyte-specific protein tyrosine kinase 0.823
CD86 CD86 molecule 0.751
ICAM1 intercellular adhesion molecule 1 0.708
CD2 CD2 molecule 0.693
HLA-DMA major histocompatibility complex, class II, DM alpha 0.690
LAT linker for activation of T cells 0.675
HLA-F major histocompatibility complex, class I, F 0.667
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.660
BTN3A3 butyrophilin, subfamily 3, member A3 0.653
HLA-G major histocompatibility complex, class I, G 0.620
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.614
TRAF1 TNF receptor-associated factor 1 0.607
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.603
HLA-B major histocompatibility complex, class I, B 0.573
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.540
BTN3A2 butyrophilin, subfamily 3, member A2 0.537
CXCL9 chemokine (C-X-C motif) ligand 9 0.492
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.479
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.427
PSEN1 presenilin 1 0.396
BTN3A1 butyrophilin, subfamily 3, member A1 0.387
CCR5 chemokine (C-C motif) receptor 5 0.353
CD247 CD247 molecule 0.352
SYK spleen tyrosine kinase 0.340
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.336
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.309
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.309
IL2RG interleukin 2 receptor, gamma 0.305
BCL10 B-cell CLL/lymphoma 10 0.305
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.294
CCL22 chemokine (C-C motif) ligand 22 0.280
CCR7 chemokine (C-C motif) receptor 7 0.276
IL1R1 interleukin 1 receptor, type I 0.274
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.268
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.268
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.247
NLRC4 NLR family, CARD domain containing 4 0.238
AOAH acyloxyacyl hydrolase (neutrophil) 0.235
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.219
IL2RB interleukin 2 receptor, beta 0.219
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.206
IL23A interleukin 23, alpha subunit p19 0.177
IRF1 interferon regulatory factor 1 0.176
EGFR epidermal growth factor receptor 0.175
BIRC2 baculoviral IAP repeat containing 2 0.167
RUNX1 runt-related transcription factor 1 0.161
SOS1 son of sevenless homolog 1 (Drosophila) 0.159
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.154
IL1B interleukin 1, beta 0.146
GRB2 growth factor receptor-bound protein 2 0.144
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 0.140
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.139
FSTL1 follistatin-like 1 0.138
DPP4 dipeptidyl-peptidase 4 0.135
CCL13 chemokine (C-C motif) ligand 13 0.131
JAK1 Janus kinase 1 0.131
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.130
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.130
LST1 leukocyte specific transcript 1 0.130
PML promyelocytic leukemia 0.129
BMPR1A bone morphogenetic protein receptor, type IA 0.124
PTPRC protein tyrosine phosphatase, receptor type, C 0.124
CD52 CD52 molecule 0.122
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.122
APH1A anterior pharynx defective 1 homolog A (C. elegans) 0.121
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.119
CCL4 chemokine (C-C motif) ligand 4 0.117
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.116
HCK hemopoietic cell kinase 0.113
CXCL10 chemokine (C-X-C motif) ligand 10 0.111
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.108
CCL8 chemokine (C-C motif) ligand 8 0.108
CLEC10A C-type lectin domain family 10, member A 0.106
IFI35 interferon-induced protein 35 0.106
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.106
CXCL11 chemokine (C-X-C motif) ligand 11 0.106
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.105
IGF2 insulin-like growth factor 2 (somatomedin A) 0.105
TRADD TNFRSF1A-associated via death domain 0.104
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.100
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 0.100
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.099
SIGLEC7 sialic acid binding Ig-like lectin 7 0.098
IL6R interleukin 6 receptor 0.096
MEFV Mediterranean fever 0.094
UBC ubiquitin C 0.092
CCL2 chemokine (C-C motif) ligand 2 0.091
CFP complement factor properdin 0.090
IFI30 interferon, gamma-inducible protein 30 0.090
XIAP X-linked inhibitor of apoptosis 0.089
IL10 interleukin 10 0.088
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.086
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.082
IRF4 interferon regulatory factor 4 0.079
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.944
RT1-Ba RT1 class II, locus Ba 0.936
Cd37 CD37 molecule 0.909
RT1-Db1 RT1 class II, locus Db1 0.660
RT1-Da RT1 class II, locus Da 0.461
RT1-Bb RT1 class II, locus Bb 0.358
Ptprc protein tyrosine phosphatase, receptor type, C 0.350
RT1-DMb RT1 class II, locus DMb 0.341
Hck hemopoietic cell kinase 0.304
Cd44 Cd44 molecule 0.258
Il2rb interleukin 2 receptor, beta 0.252
Il1b interleukin 1 beta 0.230
Psme2 proteasome (prosome, macropain) activator subunit 2 0.213
Ccl5 chemokine (C-C motif) ligand 5 0.177
Cd247 Cd247 molecule 0.169
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.126
Fgg fibrinogen gamma chain 0.104
RT1-DMa RT1 class II, locus DMa 0.098
Bin2 bridging integrator 2 0.077
Cd2 Cd2 molecule 0.073
Cfp complement factor properdin 0.073
Aif1 allograft inflammatory factor 1 0.072
Ly86 lymphocyte antigen 86 0.068
Dock8 dedicator of cytokinesis 8 0.066
Grn granulin 0.063
Slfn2 schlafen 2 0.061
Taok1 TAO kinase 1 0.058
Anxa5 annexin A5 0.057
Scp2 sterol carrier protein 2 0.056
Inpp5d inositol polyphosphate-5-phosphatase D 0.055
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.054
Ccl3 chemokine (C-C motif) ligand 3 0.054
Mybpc2 myosin binding protein C, fast-type 0.053
Il6 interleukin 6 0.052
Sell selectin L 0.050
Casp1 caspase 1 0.046
Arhgap4 Rho GTPase activating protein 4 0.045
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.045
Fyn FYN oncogene related to SRC, FGR, YES 0.043
Gzmk granzyme K 0.042
Ehf ets homologous factor 0.042
Ctsb cathepsin B 0.039
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.038
Hn1 hematological and neurological expressed 1 0.038
Vom2r27 vomeronasal 2 receptor, 27 0.037
Zbp1 Z-DNA binding protein 1 0.036
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.035
Neurl3 neuralized homolog 3 (Drosophila) 0.035
Nckap1 NCK-associated protein 1 0.031
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.030
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.029
Lst1 leukocyte specific transcript 1 0.029
Il10 interleukin 10 0.028
Arrb2 arrestin, beta 2 0.027
Cd5 Cd5 molecule 0.027
Plcg2 phospholipase C, gamma 2 0.026
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.026
Itgb7 integrin, beta 7 0.026
C5ar1 complement component 5a receptor 1 0.025
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.025
Alox5ap arachidonate 5-lipoxygenase activating protein 0.025
Igh-6 immunoglobulin heavy chain 6 0.025
Nkg7 natural killer cell group 7 sequence 0.025
Jak1 Janus kinase 1 0.024
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.024
Fgb fibrinogen beta chain 0.024
Cd86 CD86 molecule 0.024
Rab7a RAB7A, member RAS oncogene family 0.024
Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.023
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.023
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.023
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.022
Ptafr platelet-activating factor receptor 0.022
Cdc2l6 cell division cycle 2-like 6 (CDK8-like) 0.022
Il7r interleukin 7 receptor 0.021
Psme1 proteasome (prosome, macropain) activator subunit 1 0.021
Cd53 Cd53 molecule 0.021
Pecam1 platelet/endothelial cell adhesion molecule 1 0.021
Taldo1 transaldolase 1 0.021
Laptm5 lysosomal protein transmembrane 5 0.021
Il1a interleukin 1 alpha 0.021
Gfra1 GDNF family receptor alpha 1 0.020
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.020
Cxcl10 chemokine (C-X-C motif) ligand 10 0.020
Has2 hyaluronan synthase 2 0.020
Fgfr2 fibroblast growth factor receptor 2 0.020
Bmp7 bone morphogenetic protein 7 0.019
Sirpa signal-regulatory protein alpha 0.019
Spn sialophorin 0.019
Ccl4 chemokine (C-C motif) ligand 4 0.019
Pfn1 profilin 1 0.019
Cd3d CD3 molecule, delta 0.019
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.018
Tfec transcription factor EC 0.018
Il2rg interleukin 2 receptor, gamma 0.018
Tcrb T-cell receptor beta chain 0.018
Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 0.017
Cel carboxyl ester lipase 0.017
Irf5 interferon regulatory factor 5 0.017
Cd8a CD8a molecule 0.017
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism