The network for 'regulation of leukocyte proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte proliferation

Any process that modulates the frequency, rate or extent of leukocyte proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 0.999
Lyz2 lysozyme 2 0.999
Cd19 CD19 antigen 0.993
Igh immunoglobulin heavy chain complex 0.993
Cd40 CD40 antigen 0.987
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.986
Myd88 myeloid differentiation primary response gene 88 0.986
Ctnnb1 catenin (cadherin associated protein), beta 1 0.979
Tlr4 toll-like receptor 4 0.978
Ikzf1 IKAROS family zinc finger 1 0.975
Fas Fas (TNF receptor superfamily member 6) 0.974
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.967
Stat3 signal transducer and activator of transcription 3 0.967
Lta lymphotoxin A 0.952
Efnb2 ephrin B2 0.938
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.936
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.934
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.931
Foxp3 forkhead box P3 0.930
Trp53 transformation related protein 53 0.930
Ccl2 chemokine (C-C motif) ligand 2 0.924
Icos inducible T-cell co-stimulator 0.921
Ifng interferon gamma 0.917
Csf1 colony stimulating factor 1 (macrophage) 0.911
Ccr2 chemokine (C-C motif) receptor 2 0.910
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.907
Ptprc protein tyrosine phosphatase, receptor type, C 0.904
Fgfr2 fibroblast growth factor receptor 2 0.904
Cd28 CD28 antigen 0.875
Fyn Fyn proto-oncogene 0.869
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.868
Rybp RING1 and YY1 binding protein 0.859
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.849
Ccr1 chemokine (C-C motif) receptor 1 0.844
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.834
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.818
Socs1 suppressor of cytokine signaling 1 0.815
Pten phosphatase and tensin homolog 0.809
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.807
Ltb lymphotoxin B 0.794
Stat5a signal transducer and activator of transcription 5A 0.781
Fasl Fas ligand (TNF superfamily, member 6) 0.781
Drd2 dopamine receptor D2 0.780
Cd22 CD22 antigen 0.777
Mmp9 matrix metallopeptidase 9 0.767
Lepr leptin receptor 0.764
Birc3 baculoviral IAP repeat-containing 3 0.753
Zeb1 zinc finger E-box binding homeobox 1 0.751
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.735
Foxc1 forkhead box C1 0.718
Ccr6 chemokine (C-C motif) receptor 6 0.714
Cd86 CD86 antigen 0.712
Inpp5d inositol polyphosphate-5-phosphatase D 0.708
Traf6 TNF receptor-associated factor 6 0.708
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.700
Clec4n C-type lectin domain family 4, member n 0.699
Cyld cylindromatosis (turban tumor syndrome) 0.698
Rnf2 ring finger protein 2 0.697
Il2rg interleukin 2 receptor, gamma chain 0.696
Nckap1l NCK associated protein 1 like 0.690
Btk Bruton agammaglobulinemia tyrosine kinase 0.683
Bcl3 B-cell leukemia/lymphoma 3 0.664
Adam17 a disintegrin and metallopeptidase domain 17 0.650
Batf basic leucine zipper transcription factor, ATF-like 0.648
Ncoa3 nuclear receptor coactivator 3 0.648
Ccl4 chemokine (C-C motif) ligand 4 0.643
Casp8 caspase 8 0.635
Sykb spleen tyrosine kinase 0.631
Prop1 paired like homeodomain factor 1 0.628
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.621
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.613
H2-Aa histocompatibility 2, class II antigen A, alpha 0.605
Prdm1 PR domain containing 1, with ZNF domain 0.605
Il6 interleukin 6 0.600
Prf1 perforin 1 (pore forming protein) 0.592
Rarg retinoic acid receptor, gamma 0.587
Stat5b signal transducer and activator of transcription 5B 0.576
Ntf3 neurotrophin 3 0.565
Psap prosaposin 0.564
Il1b interleukin 1 beta 0.564
Irf8 interferon regulatory factor 8 0.564
Ccl12 chemokine (C-C motif) ligand 12 0.559
Rb1 retinoblastoma 1 0.557
Prkcd protein kinase C, delta 0.549
Tgfb1 transforming growth factor, beta 1 0.541
Lat linker for activation of T cells 0.540
Casp1 caspase 1 0.539
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.537
Il10ra interleukin 10 receptor, alpha 0.532
Nos1 nitric oxide synthase 1, neuronal 0.531
Inhba inhibin beta-A 0.520
Esr1 estrogen receptor 1 (alpha) 0.517
Cd4 CD4 antigen 0.515
Ticam1 toll-like receptor adaptor molecule 1 0.511
Il1rn interleukin 1 receptor antagonist 0.508
Il4 interleukin 4 0.506
Sh2d2a SH2 domain protein 2A 0.506
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.503
Hrh1 histamine receptor H1 0.503
Was Wiskott-Aldrich syndrome homolog (human) 0.499
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.999
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.999
LCK lymphocyte-specific protein tyrosine kinase 0.998
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.992
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.983
FGFR2 fibroblast growth factor receptor 2 0.975
BIRC3 baculoviral IAP repeat containing 3 0.973
CD80 CD80 molecule 0.963
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.963
SYK spleen tyrosine kinase 0.960
EGFR epidermal growth factor receptor 0.945
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.943
HLA-G major histocompatibility complex, class I, G 0.935
HLA-B major histocompatibility complex, class I, B 0.927
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.905
HLA-DRA major histocompatibility complex, class II, DR alpha 0.898
GRB2 growth factor receptor-bound protein 2 0.889
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.878
ICAM1 intercellular adhesion molecule 1 0.871
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.868
HLA-A major histocompatibility complex, class I, A 0.861
HLA-F major histocompatibility complex, class I, F 0.860
CD86 CD86 molecule 0.847
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.847
TRAF1 TNF receptor-associated factor 1 0.844
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.834
IL4R interleukin 4 receptor 0.819
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.798
HLA-DMA major histocompatibility complex, class II, DM alpha 0.794
BCL2 B-cell CLL/lymphoma 2 0.791
B2M beta-2-microglobulin 0.789
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.788
PTPRC protein tyrosine phosphatase, receptor type, C 0.787
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.785
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.767
SOCS3 suppressor of cytokine signaling 3 0.743
HLA-C major histocompatibility complex, class I, C 0.705
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.705
CXCL9 chemokine (C-X-C motif) ligand 9 0.705
IL1B interleukin 1, beta 0.695
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.686
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.679
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.669
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.660
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.652
RB1 retinoblastoma 1 0.648
CD247 CD247 molecule 0.641
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.632
IL8 interleukin 8 0.630
CXCL10 chemokine (C-X-C motif) ligand 10 0.620
LAT linker for activation of T cells 0.595
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.586
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.578
BCL2L1 BCL2-like 1 0.578
CCR1 chemokine (C-C motif) receptor 1 0.572
BTN3A2 butyrophilin, subfamily 3, member A2 0.566
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.563
INSR insulin receptor 0.557
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.555
HLA-DMB major histocompatibility complex, class II, DM beta 0.554
IL10RA interleukin 10 receptor, alpha 0.545
HLA-E major histocompatibility complex, class I, E 0.539
BTN3A1 butyrophilin, subfamily 3, member A1 0.529
IL2RG interleukin 2 receptor, gamma 0.507
CCL2 chemokine (C-C motif) ligand 2 0.485
CCR7 chemokine (C-C motif) receptor 7 0.479
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.462
BTN3A3 butyrophilin, subfamily 3, member A3 0.452
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.450
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.417
CD2 CD2 molecule 0.406
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.403
CCR5 chemokine (C-C motif) receptor 5 0.403
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.396
CD48 CD48 molecule 0.390
HCK hemopoietic cell kinase 0.388
HDAC9 histone deacetylase 9 0.387
TFF1 trefoil factor 1 0.384
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.380
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.369
CCL4 chemokine (C-C motif) ligand 4 0.362
PLCG1 phospholipase C, gamma 1 0.358
BCL2A1 BCL2-related protein A1 0.354
BAX BCL2-associated X protein 0.354
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.352
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.347
TLR2 toll-like receptor 2 0.344
CXCL2 chemokine (C-X-C motif) ligand 2 0.343
LIF leukemia inhibitory factor (cholinergic differentiation factor) 0.328
ABI1 abl-interactor 1 0.326
PTK2 PTK2 protein tyrosine kinase 2 0.323
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.312
CCL8 chemokine (C-C motif) ligand 8 0.307
PAX3 paired box 3 0.305
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.303
CD163 CD163 molecule 0.297
TGIF1 TGFB-induced factor homeobox 1 0.296
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.281
TANK TRAF family member-associated NFKB activator 0.276
CD33 CD33 molecule 0.272
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Da RT1 class II, locus Da 0.951
RT1-Ba RT1 class II, locus Ba 0.670
Cd37 CD37 molecule 0.383
RT1-Db1 RT1 class II, locus Db1 0.289
RT1-Bb RT1 class II, locus Bb 0.263
Cd247 Cd247 molecule 0.244
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.194
RT1-DMb RT1 class II, locus DMb 0.124
Nkg7 natural killer cell group 7 sequence 0.088
Cd2 Cd2 molecule 0.085
Vip vasoactive intestinal peptide 0.076
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.076
Ciita class II, major histocompatibility complex, transactivator 0.075
Napsa napsin A aspartic peptidase 0.073
Il1b interleukin 1 beta 0.071
Il10 interleukin 10 0.069
Itgb7 integrin, beta 7 0.067
Aif1 allograft inflammatory factor 1 0.062
Il1rl1 interleukin 1 receptor-like 1 0.062
Hck hemopoietic cell kinase 0.061
Slfn2 schlafen 2 0.056
Cfp complement factor properdin 0.055
Fam108b1 family with sequence similarity 108, member B1 0.048
Casp1 caspase 1 0.048
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.046
Cd5 Cd5 molecule 0.046
Inpp5d inositol polyphosphate-5-phosphatase D 0.045
Mmp10 matrix metallopeptidase 10 0.043
Tas2r123 taste receptor, type 2, member 123 0.042
Met met proto-oncogene 0.041
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.041
RT1-DMa RT1 class II, locus DMa 0.040
Bin2 bridging integrator 2 0.038
Ptprc protein tyrosine phosphatase, receptor type, C 0.037
Reg3b regenerating islet-derived 3 beta 0.036
Cd38 CD38 molecule 0.036
Serpinb1a serine (or cysteine) proteinase inhibitor, clade B, member 1a 0.033
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.032
Gfi1 growth factor independent 1 transcription repressor 0.032
Sell selectin L 0.032
Spn sialophorin 0.030
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.030
Lef1 lymphoid enhancer binding factor 1 0.030
Ppyr1 pancreatic polypeptide receptor 1 0.030
Il1r1 interleukin 1 receptor, type I 0.030
Il18 interleukin 18 0.029
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.029
Cd22 CD22 molecule 0.029
Scn11a sodium channel, voltage-gated, type XI, alpha 0.028
Cd44 Cd44 molecule 0.028
Csf1 colony stimulating factor 1 (macrophage) 0.027
Il4 interleukin 4 0.027
Reg3g regenerating islet-derived 3 gamma 0.027
Anxa2 annexin A2 0.026
Prss2 protease, serine, 2 0.026
Tgm1 transglutaminase 1, K polypeptide 0.026
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.026
Gpr114 G protein-coupled receptor 114 0.025
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.025
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.025
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.025
Zbp1 Z-DNA binding protein 1 0.025
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.024
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.024
Twist2 twist homolog 2 (Drosophila) 0.024
Aqp8 aquaporin 8 0.023
Vom2r27 vomeronasal 2 receptor, 27 0.023
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.023
UST4r integral membrane transport protein UST4r 0.023
Il1rl2 interleukin 1 receptor-like 2 0.023
Syt8 synaptotagmin VIII 0.023
C1qb complement component 1, q subcomponent, B chain 0.022
Dcaf17 DDB1 and CUL4 associated factor 17 0.022
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.022
Itgad integrin, alpha D 0.022
Socs3 suppressor of cytokine signaling 3 0.022
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.022
Lcp2 lymphocyte cytosolic protein 2 0.021
Serpinb7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.021
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.021
Ccl3 chemokine (C-C motif) ligand 3 0.021
C3 complement component 3 0.021
Zg16 zymogen granule protein 16 0.021
Pth parathyroid hormone 0.021
Fgb fibrinogen beta chain 0.020
Arhgap4 Rho GTPase activating protein 4 0.020
Il6 interleukin 6 0.020
Ccr5 chemokine (C-C motif) receptor 5 0.020
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.020
Adfp adipose differentiation related protein 0.020
Laptm5 lysosomal protein transmembrane 5 0.020
LOC100361571 keratin associated protein 1-3-like 0.020
Prr13 proline rich 13 0.020
Impg2 interphotoreceptor matrix proteoglycan 2 0.020
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.020
Gpr20 G protein-coupled receptor 20 0.020
Cd53 Cd53 molecule 0.019
Calca calcitonin-related polypeptide alpha 0.019
Arhgap25 Rho GTPase activating protein 25 0.019
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.019
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism