The network for 'regulation of lymphocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lymphocyte differentiation

Any process that modulates the frequency, rate or extent of lymphocyte differentiation.

Mus musculus
Name Description Probability Func Analog Organism
Ikzf1 IKAROS family zinc finger 1 0.998
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.997
Tnf tumor necrosis factor 0.996
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.994
Pten phosphatase and tensin homolog 0.993
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.972
Stat3 signal transducer and activator of transcription 3 0.969
Grb2 growth factor receptor bound protein 2 0.944
Foxp3 forkhead box P3 0.942
Fas Fas (TNF receptor superfamily member 6) 0.936
Inpp5d inositol polyphosphate-5-phosphatase D 0.928
Cd19 CD19 antigen 0.919
Rybp RING1 and YY1 binding protein 0.905
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.896
Gli2 GLI-Kruppel family member GLI2 0.896
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.895
Apc adenomatosis polyposis coli 0.874
Foxn1 forkhead box N1 0.859
Trp53 transformation related protein 53 0.856
Cd28 CD28 antigen 0.855
Cd247 CD247 antigen 0.853
Ptgs2 prostaglandin-endoperoxide synthase 2 0.832
Cbl Casitas B-lineage lymphoma 0.830
Il1r1 interleukin 1 receptor, type I 0.829
Csf1 colony stimulating factor 1 (macrophage) 0.820
Stat5a signal transducer and activator of transcription 5A 0.813
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.796
Tgfbr2 transforming growth factor, beta receptor II 0.796
Il2rg interleukin 2 receptor, gamma chain 0.782
Plcg2 phospholipase C, gamma 2 0.772
Lta lymphotoxin A 0.763
Ar androgen receptor 0.754
Foxc1 forkhead box C1 0.747
Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) 0.746
Runx1 runt related transcription factor 1 0.744
Lepr leptin receptor 0.737
Il10 interleukin 10 0.733
Ren1 renin 1 structural 0.730
Socs3 suppressor of cytokine signaling 3 0.728
Stat5b signal transducer and activator of transcription 5B 0.727
Bmi1 Bmi1 polycomb ring finger oncogene 0.721
Ifng interferon gamma 0.714
Rxra retinoid X receptor alpha 0.706
Zeb1 zinc finger E-box binding homeobox 1 0.681
Vegfa vascular endothelial growth factor A 0.677
Rag1 recombination activating gene 1 0.670
Shc1 src homology 2 domain-containing transforming protein C1 0.666
Plcg1 phospholipase C, gamma 1 0.659
Fgfr2 fibroblast growth factor receptor 2 0.657
Rnf2 ring finger protein 2 0.651
Kit kit oncogene 0.638
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.600
Ccr7 chemokine (C-C motif) receptor 7 0.588
Nlrp3 NLR family, pyrin domain containing 3 0.565
Jak3 Janus kinase 3 0.561
Bcl3 B-cell leukemia/lymphoma 3 0.555
Sfpi1 SFFV proviral integration 1 0.555
Jak2 Janus kinase 2 0.551
Prf1 perforin 1 (pore forming protein) 0.539
Stat6 signal transducer and activator of transcription 6 0.522
Cd44 CD44 antigen 0.507
Bmpr1a bone morphogenetic protein receptor, type 1A 0.505
Nf1 neurofibromatosis 1 0.501
Tgfb2 transforming growth factor, beta 2 0.498
Il2 interleukin 2 0.496
Fyn Fyn proto-oncogene 0.493
Sox9 SRY-box containing gene 9 0.487
Il2rb interleukin 2 receptor, beta chain 0.482
Il6st interleukin 6 signal transducer 0.480
Nos3 nitric oxide synthase 3, endothelial cell 0.476
Lck lymphocyte protein tyrosine kinase 0.450
Id3 inhibitor of DNA binding 3 0.442
H2-Aa histocompatibility 2, class II antigen A, alpha 0.442
Gata6 GATA binding protein 6 0.440
Stat2 signal transducer and activator of transcription 2 0.436
Id1 inhibitor of DNA binding 1 0.424
Btk Bruton agammaglobulinemia tyrosine kinase 0.421
Tgfb1 transforming growth factor, beta 1 0.417
Rarg retinoic acid receptor, gamma 0.409
Lat linker for activation of T cells 0.404
Tcra T-cell receptor alpha chain 0.395
Cd80 CD80 antigen 0.385
Lag3 lymphocyte-activation gene 3 0.385
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.373
Ctla2b cytotoxic T lymphocyte-associated protein 2 beta 0.372
Blnk B-cell linker 0.370
Rel reticuloendotheliosis oncogene 0.365
Cd40 CD40 antigen 0.362
Ltb lymphotoxin B 0.360
Ctnnb1 catenin (cadherin associated protein), beta 1 0.352
Esr1 estrogen receptor 1 (alpha) 0.352
Atxn1 ataxin 1 0.350
Irf9 interferon regulatory factor 9 0.349
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.348
Pthlh parathyroid hormone-like peptide 0.341
Runx2 runt related transcription factor 2 0.340
Gata4 GATA binding protein 4 0.338
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.335
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.333
Il1b interleukin 1 beta 0.326
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HLA-B major histocompatibility complex, class I, B 0.773
HLA-G major histocompatibility complex, class I, G 0.658
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.525
LAT linker for activation of T cells 0.504
HLA-DRA major histocompatibility complex, class II, DR alpha 0.385
BIRC3 baculoviral IAP repeat containing 3 0.331
HLA-F major histocompatibility complex, class I, F 0.305
IL4R interleukin 4 receptor 0.260
EGFR epidermal growth factor receptor 0.252
HLA-E major histocompatibility complex, class I, E 0.223
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.215
NCOR2 nuclear receptor corepressor 2 0.198
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.191
B2M beta-2-microglobulin 0.183
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.176
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.163
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.143
IL2RG interleukin 2 receptor, gamma 0.143
HLA-C major histocompatibility complex, class I, C 0.133
LIN9 lin-9 homolog (C. elegans) 0.117
AXL AXL receptor tyrosine kinase 0.107
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.092
CD80 CD80 molecule 0.086
PILRA paired immunoglobin-like type 2 receptor alpha 0.084
BMPR1A bone morphogenetic protein receptor, type IA 0.082
HLA-A major histocompatibility complex, class I, A 0.081
GHR growth hormone receptor 0.074
PLCG1 phospholipase C, gamma 1 0.073
ICAM1 intercellular adhesion molecule 1 0.068
PML promyelocytic leukemia 0.067
GAS6 growth arrest-specific 6 0.066
CD86 CD86 molecule 0.065
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.059
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.054
IL4 interleukin 4 0.054
EPOR erythropoietin receptor 0.053
ESR1 estrogen receptor 1 0.047
NCOR1 nuclear receptor corepressor 1 0.044
CD22 CD22 molecule 0.043
TGIF1 TGFB-induced factor homeobox 1 0.040
HLA-DMB major histocompatibility complex, class II, DM beta 0.040
IL2RB interleukin 2 receptor, beta 0.039
IL15 interleukin 15 0.039
INSR insulin receptor 0.035
PPARA peroxisome proliferator-activated receptor alpha 0.034
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.034
IL15RA interleukin 15 receptor, alpha 0.033
FSTL1 follistatin-like 1 0.033
MED25 mediator complex subunit 25 0.033
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.032
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.032
SOCS3 suppressor of cytokine signaling 3 0.032
SH3KBP1 SH3-domain kinase binding protein 1 0.030
IL1R1 interleukin 1 receptor, type I 0.029
CCND3 cyclin D3 0.028
CXCL2 chemokine (C-X-C motif) ligand 2 0.028
BCL10 B-cell CLL/lymphoma 10 0.027
CTBP1 C-terminal binding protein 1 0.026
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.025
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.024
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.024
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.023
GRAP2 GRB2-related adaptor protein 2 0.022
GAB1 GRB2-associated binding protein 1 0.022
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.022
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.021
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.021
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.020
CDK6 cyclin-dependent kinase 6 0.020
LIN54 lin-54 homolog (C. elegans) 0.020
CXCR4 chemokine (C-X-C motif) receptor 4 0.020
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.020
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.019
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.019
SLAMF1 signaling lymphocytic activation molecule family member 1 0.019
SH3BP2 SH3-domain binding protein 2 0.019
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.019
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.019
NOD2 nucleotide-binding oligomerization domain containing 2 0.018
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.018
CD33 CD33 molecule 0.018
CCND1 cyclin D1 0.018
CCL5 chemokine (C-C motif) ligand 5 0.018
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.018
SMAD7 SMAD family member 7 0.018
CD40 CD40 molecule, TNF receptor superfamily member 5 0.017
PINK1 PTEN induced putative kinase 1 0.017
ENG endoglin 0.017
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.017
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.017
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.017
HDAC9 histone deacetylase 9 0.016
CAV1 caveolin 1, caveolae protein, 22kDa 0.016
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.016
RXRA retinoid X receptor, alpha 0.015
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.015
CD247 CD247 molecule 0.015
IL6R interleukin 6 receptor 0.015
HCK hemopoietic cell kinase 0.015
PTPRJ protein tyrosine phosphatase, receptor type, J 0.015
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-Db1 RT1 class II, locus Db1 0.086
RT1-Da RT1 class II, locus Da 0.035
Cd37 CD37 molecule 0.021
Il2rb interleukin 2 receptor, beta 0.017
Cd3g CD3 molecule, gamma 0.014
Tgfbr2 transforming growth factor, beta receptor II 0.013
RT1-Bb RT1 class II, locus Bb 0.013
Hck hemopoietic cell kinase 0.012
Spn sialophorin 0.011
Il1r1 interleukin 1 receptor, type I 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism