Process View
The network for 'positive regulation of apoptotic signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Pten | phosphatase and tensin homolog | 1.000 | |
Trp53 | transformation related protein 53 | 1.000 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 1.000 | |
Tgfb1 | transforming growth factor, beta 1 | 0.995 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.992 | |
Apc | adenomatosis polyposis coli | 0.991 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.988 | |
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.988 | |
Psen1 | presenilin 1 | 0.987 | |
Bax | BCL2-associated X protein | 0.986 | |
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.984 | |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.980 | |
Apaf1 | apoptotic peptidase activating factor 1 | 0.978 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.977 | |
Lepr | leptin receptor | 0.971 | |
Mapk8 | mitogen-activated protein kinase 8 | 0.964 | |
Tnf | tumor necrosis factor | 0.962 | |
Cd44 | CD44 antigen | 0.961 | |
Ncoa3 | nuclear receptor coactivator 3 | 0.959 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.944 | |
Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.933 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.925 | |
Rxra | retinoid X receptor alpha | 0.914 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.912 | |
Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.903 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.900 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.900 | |
Il2rg | interleukin 2 receptor, gamma chain | 0.897 | |
Fyn | Fyn proto-oncogene | 0.895 | |
Nf1 | neurofibromatosis 1 | 0.894 | |
Lyz2 | lysozyme 2 | 0.873 | |
Vhl | von Hippel-Lindau tumor suppressor | 0.869 | |
Axin1 | axin 1 | 0.868 | |
Sfrp2 | secreted frizzled-related protein 2 | 0.863 | |
Casp8 | caspase 8 | 0.861 | |
Ikbkg | inhibitor of kappaB kinase gamma | 0.857 | |
Esr1 | estrogen receptor 1 (alpha) | 0.857 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.851 | |
Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.848 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.844 | |
Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.837 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.818 | |
Nos2 | nitric oxide synthase 2, inducible | 0.816 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.815 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.813 | |
Hif1a | hypoxia inducible factor 1, alpha subunit | 0.811 | |
Vegfa | vascular endothelial growth factor A | 0.808 | |
Shh | sonic hedgehog | 0.806 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.796 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.795 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.793 | |
Fst | follistatin | 0.787 | |
Stk3 | serine/threonine kinase 3 (Ste20, yeast homolog) | 0.772 | |
Ilk | integrin linked kinase | 0.769 | |
Rb1 | retinoblastoma 1 | 0.741 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.740 | |
Stk4 | serine/threonine kinase 4 | 0.730 | |
Rara | retinoic acid receptor, alpha | 0.728 | |
Vdr | vitamin D receptor | 0.713 | |
Ptch1 | patched homolog 1 | 0.709 | |
Tgfb2 | transforming growth factor, beta 2 | 0.698 | |
Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.691 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.676 | |
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.675 | |
Mcl1 | myeloid cell leukemia sequence 1 | 0.655 | |
Aim2 | absent in melanoma 2 | 0.653 | |
Bcl3 | B-cell leukemia/lymphoma 3 | 0.649 | |
Stat3 | signal transducer and activator of transcription 3 | 0.627 | |
Wrn | Werner syndrome homolog (human) | 0.617 | |
Col1a1 | collagen, type I, alpha 1 | 0.611 | |
Nos1 | nitric oxide synthase 1, neuronal | 0.606 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.606 | |
Myc | myelocytomatosis oncogene | 0.603 | |
Mfn2 | mitofusin 2 | 0.602 | |
Igh | immunoglobulin heavy chain complex | 0.577 | |
Tlr4 | toll-like receptor 4 | 0.576 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.568 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.568 | |
Skil | SKI-like | 0.563 | |
Rbl1 | retinoblastoma-like 1 (p107) | 0.561 | |
Lep | leptin | 0.557 | |
Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.556 | |
Nlrp3 | NLR family, pyrin domain containing 3 | 0.553 | |
Cdk4 | cyclin-dependent kinase 4 | 0.547 | |
Ctsl | cathepsin L | 0.545 | |
Rarg | retinoic acid receptor, gamma | 0.543 | |
Sox9 | SRY-box containing gene 9 | 0.536 | |
Il6st | interleukin 6 signal transducer | 0.534 | |
Sfrp1 | secreted frizzled-related protein 1 | 0.529 | |
Vcl | vinculin | 0.523 | |
Casp3 | caspase 3 | 0.523 | |
Daxx | Fas death domain-associated protein | 0.522 | |
Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.519 | |
Prlr | prolactin receptor | 0.517 | |
Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.512 | |
Ahr | aryl-hydrocarbon receptor | 0.508 | |
Ikzf1 | IKAROS family zinc finger 1 | 0.495 | |
Prkce | protein kinase C, epsilon | 0.495 | |
Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.490 | |
Atf2 | activating transcription factor 2 | 0.481 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
rhogb | ras homolog gene family, member Gb | 0.551 | |
baxa | bcl2-associated X protein, a | 0.461 | |
mcl1a | myeloid cell leukemia sequence 1a | 0.328 | |
ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.299 | |
manf | mesencephalic astrocyte-derived neurotrophic factor | 0.299 | |
nf1a | neurofibromin 1a | 0.292 | |
bcl2l1 | bcl2-like 1 | 0.289 | |
sgk1 | serum/glucocorticoid regulated kinase 1 | 0.284 | |
frem3 | Fras1 related extracellular matrix 3 | 0.261 | |
tbx1 | T-box 1 | 0.217 | |
tnfrsfa | tumor necrosis factor receptor superfamily, member a | 0.213 | |
bmp2b | bone morphogenetic protein 2b | 0.200 | |
acvr2a | activin receptor IIa | 0.199 | |
rpsa | ribosomal protein SA | 0.190 | |
ikzf1 | IKAROS family zinc finger 1 (Ikaros) | 0.153 | |
nf1b | neurofibromin 1b | 0.151 | |
gnb2l1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | 0.145 | |
rag1 | recombination activating gene 1 | 0.139 | |
sulf2l | sulfatase 2, like | 0.134 | |
inhbaa | inhibin, beta Aa | 0.130 | |
bactin1 | bactin1 | 0.130 | |
fgf3 | fibroblast growth factor 3 | 0.127 | |
atf3 | activating transcription factor 3 | 0.127 | |
socs3a | suppressor of cytokine signaling 3a | 0.126 | |
cotl1 | coactosin-like 1 (Dictyostelium) | 0.114 | |
cyp24a1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.113 | |
inha | inhibin, alpha | 0.106 | |
bida | BH3 interacting domain death agonist | 0.105 | |
nkx2.3 | NK2 transcription factor related 3 | 0.105 | |
il7r | interleukin 7 receptor | 0.105 | |
wnt4a | wingless-type MMTV integration site family, member 4a | 0.104 | |
ube4b | ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) | 0.101 | |
ifnphi1 | interferon phi 1 | 0.097 | |
junb | jun B proto-oncogene | 0.095 | |
evpl | envoplakin | 0.095 | |
rhoaa | ras homolog gene family, member Aa | 0.095 | |
tagln2 | transgelin 2 | 0.095 | |
calrl | calreticulin like | 0.094 | |
plxnb2a | plexin b2a | 0.092 | |
pitx3 | paired-like homeodomain transcription factor 3 | 0.091 | |
spi1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.091 | |
pax9 | paired box gene 9 | 0.089 | |
plxnd1 | plexin D1 | 0.085 | |
bcl2 | B-cell leukemia/lymphoma 2 | 0.085 | |
acadl | acyl-Coenzyme A dehydrogenase, long chain | 0.083 | |
mcl1b | myeloid cell leukemia sequence 1b | 0.082 | |
cdkn1a | cyclin-dependent kinase inhibitor 1A | 0.082 | |
ptpn11a | protein tyrosine phosphatase, non-receptor type 11, a | 0.082 | |
uba1 | ubiquitin-like modifier activating enzyme 1 | 0.082 | |
mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.082 | |
stau2 | staufen, RNA binding protein, homolog 2 (Drosophila) | 0.082 | |
rspo3 | R-spondin 3 homolog (Xenopus laevis) | 0.082 | |
yes1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.082 | |
ret1 | receptor tyrosine kinase | 0.081 | |
tcf21 | transcription factor 21 | 0.081 | |
nrarpa | notch-regulated ankyrin repeat protein a | 0.081 | |
tcf7 | transcription factor 7 (T-cell specific, HMG-box) | 0.081 | |
gadd45aa | growth arrest and DNA-damage-inducible, alpha, a | 0.081 | |
cnih | cornichon homolog (Drosophila) | 0.081 | |
mobkl2a | MOB1, Mps One Binder kinase activator-like 2A (yeast) | 0.079 | |
hbegfa | heparin-binding EGF-like growth factor a | 0.079 | |
polb | polymerase (DNA directed), beta | 0.078 | |
si:ch211-51m24.3 | si:ch211-51m24.3 | 0.078 | |
tp53bp2 | tumor protein p53 binding protein, 2 | 0.078 | |
ahcyl1 | S-adenosylhomocysteine hydrolase-like 1 | 0.077 | |
mapk6 | mitogen-activated protein kinase 6 | 0.077 | |
nme2b.1 | non-metastatic cells 2b.1, protein (NM23B) expressed in | 0.077 | |
zgc:92872 | zgc:92872 | 0.077 | |
ndufv1 | NADH dehydrogenase (ubiquinone) flavoprotein 1 | 0.076 | |
LOC567131 | calcitonin gene-related peptide type 1 receptor-like | 0.075 | |
ybx1 | Y box binding protein 1 | 0.075 | |
tssc1 | tumor suppressing subtransferable candidate 1 | 0.075 | |
appb | amyloid beta (A4) precursor protein b | 0.075 | |
zgc:101724 | zgc:101724 | 0.074 | |
LOC556647 | GDNF family receptor alpha-4-like | 0.074 | |
timp2b | tissue inhibitor of metalloproteinase 2b | 0.073 | |
rag2 | recombination activating gene 2 | 0.073 | |
plag1 | pleiomorphic adenoma gene 1 | 0.073 | |
fzd7a | frizzled homolog 7a | 0.073 | |
zgc:92360 | zgc:92360 | 0.072 | |
mdm2 | transformed 3T3 cell double minute 2 homolog (mouse) | 0.072 | |
satb2 | SATB homeobox 2 | 0.072 | |
eef1g | eukaryotic translation elongation factor 1 gamma | 0.071 | |
stc1l | stanniocalcin 1, like | 0.071 | |
ubtd2 | ubiquitin domain containing 2 | 0.071 | |
rarga | retinoic acid receptor gamma a | 0.071 | |
lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.071 | |
fos | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0.069 | |
cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.069 | |
zfp36l1a | zinc finger protein 36, C3H type-like 1a | 0.068 | |
crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.068 | |
nkx3.2 | NK3 homeobox 2 | 0.068 | |
sid4 | secreted immunoglobulin domain 4 | 0.067 | |
rpl8 | ribosomal protein L8 | 0.067 | |
mapk7 | mitogen-activated protein kinase 7 | 0.066 | |
rpl13 | ribosomal protein L13 | 0.066 | |
sdcbp | syndecan binding protein (syntenin) | 0.065 | |
otpa | orthopedia homolog a | 0.065 | |
zgc:101679 | zgc:101679 | 0.064 | |
jun | jun proto-oncogene | 0.064 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
park | parkin | 0.682 | |
th | thread | 0.581 | |
rpr | reaper | 0.510 | |
Ice | CG7788 gene product from transcript CG7788-RA | 0.472 | |
Dcr-2 | Dicer-2 | 0.257 | |
caz | cabeza | 0.242 | |
imd | immune deficiency | 0.226 | |
G-salpha60A | G protein salpha 60A | 0.214 | |
Nc | Nedd2-like caspase | 0.207 | |
jar | jaguar | 0.190 | |
Csp | Cysteine string protein | 0.180 | |
not | non-stop | 0.166 | |
CadN | Cadherin-N | 0.165 | |
RagA | CG11968 gene product from transcript CG11968-RA | 0.159 | |
Dcp-1 | Death caspase-1 | 0.157 | |
smi35A | smell impaired 35A | 0.150 | |
Rac1 | CG2248 gene product from transcript CG2248-RA | 0.137 | |
CG8443 | CG8443 gene product from transcript CG8443-RA | 0.136 | |
ap | apterous | 0.135 | |
Sod2 | Superoxide dismutase 2 (Mn) | 0.133 | |
Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.126 | |
NetB | Netrin-B | 0.122 | |
sd | scalloped | 0.110 | |
slmb | supernumerary limbs | 0.108 | |
CG1021 | CG1021 gene product from transcript CG1021-RE | 0.102 | |
Cat | Catalase | 0.098 | |
bur | burgundy | 0.098 | |
bsk | basket | 0.094 | |
RpS13 | Ribosomal protein S13 | 0.092 | |
Ark | Apaf-1-related-killer | 0.092 | |
debcl | death executioner Bcl-2 homologue | 0.091 | |
Psn | Presenilin | 0.087 | |
babo | baboon | 0.085 | |
Letm1 | CG4589 gene product from transcript CG4589-RB | 0.085 | |
Patr-1 | Protein associated with topo II related - 1 | 0.084 | |
repo | reversed polarity | 0.081 | |
CG6543 | CG6543 gene product from transcript CG6543-RA | 0.079 | |
Cdk5alpha | Cdk5 activator-like protein | 0.079 | |
Adf1 | Adh transcription factor 1 | 0.076 | |
Mtor | Megator | 0.076 | |
Cyt-c-d | Cytochrome c distal | 0.074 | |
W | Wrinkled | 0.073 | |
Adar | Adenosine deaminase acting on RNA | 0.073 | |
poe | purity of essence | 0.069 | |
eya | eyes absent | 0.068 | |
Mical | Molecule interacting with CasL | 0.067 | |
myoglianin | CG1838 gene product from transcript CG1838-RD | 0.067 | |
CG13890 | CG13890 gene product from transcript CG13890-RA | 0.066 | |
TBPH | CG10327 gene product from transcript CG10327-RC | 0.066 | |
bchs | blue cheese | 0.065 | |
CG1103 | CG1103 gene product from transcript CG1103-RA | 0.065 | |
Su(H) | Suppressor of Hairless | 0.063 | |
kek5 | kekkon5 | 0.062 | |
ird1 | immune response deficient 1 | 0.062 | |
yki | yorkie | 0.062 | |
yuri | yuri gagarin | 0.061 | |
cpx | complexin | 0.061 | |
CG10984 | CG10984 gene product from transcript CG10984-RC | 0.060 | |
Roc1b | CG16988 gene product from transcript CG16988-RA | 0.060 | |
Taz | Tafazzin | 0.060 | |
BG4 | CG12297 gene product from transcript CG12297-RA | 0.060 | |
nvy | nervy | 0.059 | |
spas | spastin | 0.056 | |
tbce | tubulin-specific chaperone E | 0.056 | |
Cdc42 | CG12530 gene product from transcript CG12530-RA | 0.056 | |
CG10098 | CG10098 gene product from transcript CG10098-RA | 0.055 | |
calypso | CG8445 gene product from transcript CG8445-RB | 0.055 | |
Eip71CD | Ecdysone-induced protein 28/29kD | 0.055 | |
CG30410 | CG30410 gene product from transcript CG30410-RB | 0.054 | |
Lis-1 | Lissencephaly-1 | 0.054 | |
tsr | twinstar | 0.054 | |
vimar | visceral mesodermal armadillo-repeats | 0.054 | |
CG7372 | CG7372 gene product from transcript CG7372-RA | 0.052 | |
RpS24 | Ribosomal protein S24 | 0.052 | |
drl | derailed | 0.052 | |
dve | defective proventriculus | 0.051 | |
Atg6 | Autophagy-specific gene 6 | 0.051 | |
mib1 | mind bomb 1 | 0.050 | |
dj | don juan | 0.049 | |
CG11267 | CG11267 gene product from transcript CG11267-RA | 0.049 | |
GLaz | Glial Lazarillo | 0.049 | |
Npc1a | Niemann-Pick type C-1a | 0.049 | |
Atg7 | Autophagy-specific gene 7 | 0.048 | |
CG42574 | CG42574 gene product from transcript CG42574-RE | 0.046 | |
APP-BP1 | beta-Amyloid precursor protein binding protein 1 | 0.045 | |
trio | CG18214 gene product from transcript CG18214-RA | 0.045 | |
uzip | unzipped | 0.045 | |
Magi | CG30388 gene product from transcript CG30388-RA | 0.045 | |
MED1 | Mediator complex subunit 1 | 0.044 | |
Unc-76 | CG3981 gene product from transcript CG3981-RB | 0.044 | |
hpo | hippo | 0.044 | |
fs(2)ltoPP43 | female sterile (2) ltoPP43 | 0.044 | |
X11L | CG5675 gene product from transcript CG5675-RB | 0.043 | |
tan | tantalus | 0.043 | |
HtrA2 | CG8464 gene product from transcript CG8464-RA | 0.043 | |
Ppat-Dpck | Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase | 0.043 | |
VGAT | Vesicular GABA Transporter | 0.043 | |
alphaTub84B | alpha-Tubulin at 84B | 0.042 | |
neuroligin | CG13772 gene product from transcript CG13772-RA | 0.042 | |
CG12214 | CG12214 gene product from transcript CG12214-RB | 0.041 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
BCL2L1 | BCL2-like 1 | 1.000 | |
BCL2 | B-cell CLL/lymphoma 2 | 1.000 | |
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.000 | |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 1.000 | |
FAS | Fas (TNF receptor superfamily, member 6) | 1.000 | |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 1.000 | |
XIAP | X-linked inhibitor of apoptosis | 0.999 | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.999 | |
BIRC3 | baculoviral IAP repeat containing 3 | 0.998 | |
TRAF1 | TNF receptor-associated factor 1 | 0.997 | |
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.996 | |
BAX | BCL2-associated X protein | 0.996 | |
EGFR | epidermal growth factor receptor | 0.993 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.982 | |
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.981 | |
BIRC2 | baculoviral IAP repeat containing 2 | 0.979 | |
FADD | Fas (TNFRSF6)-associated via death domain | 0.978 | |
BAD | BCL2-associated agonist of cell death | 0.975 | |
TRAF2 | TNF receptor-associated factor 2 | 0.974 | |
BID | BH3 interacting domain death agonist | 0.972 | |
SQSTM1 | sequestosome 1 | 0.967 | |
UBC | ubiquitin C | 0.965 | |
DAXX | death-domain associated protein | 0.965 | |
TRADD | TNFRSF1A-associated via death domain | 0.959 | |
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.957 | |
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.949 | |
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.948 | |
TRAF3 | TNF receptor-associated factor 3 | 0.930 | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.928 | |
PML | promyelocytic leukemia | 0.926 | |
S100A6 | S100 calcium binding protein A6 | 0.921 | |
MAPK1 | mitogen-activated protein kinase 1 | 0.921 | |
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.917 | |
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.905 | |
TP53BP2 | tumor protein p53 binding protein, 2 | 0.905 | |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.882 | |
ZMYND11 | zinc finger, MYND-type containing 11 | 0.879 | |
PSEN1 | presenilin 1 | 0.871 | |
CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.861 | |
S100B | S100 calcium binding protein B | 0.855 | |
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.854 | |
TRAF6 | TNF receptor-associated factor 6 | 0.845 | |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.832 | |
BAK1 | BCL2-antagonist/killer 1 | 0.824 | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.801 | |
APP | amyloid beta (A4) precursor protein | 0.759 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.748 | |
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.748 | |
MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.742 | |
BECN1 | beclin 1, autophagy related | 0.739 | |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.736 | |
PTEN | phosphatase and tensin homolog | 0.696 | |
STK4 | serine/threonine kinase 4 | 0.678 | |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.648 | |
BCAP31 | B-cell receptor-associated protein 31 | 0.636 | |
BIK | BCL2-interacting killer (apoptosis-inducing) | 0.628 | |
TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.618 | |
SMAD7 | SMAD family member 7 | 0.608 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.602 | |
TP53 | tumor protein p53 | 0.587 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.574 | |
CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.557 | |
TGFB1 | transforming growth factor, beta 1 | 0.551 | |
S100A1 | S100 calcium binding protein A1 | 0.550 | |
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.545 | |
S100A4 | S100 calcium binding protein A4 | 0.542 | |
SEPT2 | septin 2 | 0.528 | |
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.523 | |
TANK | TRAF family member-associated NFKB activator | 0.518 | |
NCF2 | neutrophil cytosolic factor 2 | 0.517 | |
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.515 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.508 | |
SFPQ | splicing factor proline/glutamine-rich | 0.501 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.497 | |
MAPK8 | mitogen-activated protein kinase 8 | 0.494 | |
SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.493 | |
BBC3 | BCL2 binding component 3 | 0.489 | |
NLRC4 | NLR family, CARD domain containing 4 | 0.483 | |
ANXA1 | annexin A1 | 0.473 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.470 | |
GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.470 | |
BMP2 | bone morphogenetic protein 2 | 0.468 | |
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.464 | |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.445 | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.443 | |
S100A11 | S100 calcium binding protein A11 | 0.440 | |
GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.440 | |
SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.405 | |
STRN3 | striatin, calmodulin binding protein 3 | 0.394 | |
SP100 | SP100 nuclear antigen | 0.386 | |
DIABLO | diablo, IAP-binding mitochondrial protein | 0.384 | |
STK3 | serine/threonine kinase 3 | 0.369 | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.364 | |
IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.357 | |
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.334 | |
HDAC1 | histone deacetylase 1 | 0.316 | |
PRKCA | protein kinase C, alpha | 0.316 | |
HIPK2 | homeodomain interacting protein kinase 2 | 0.309 | |
ANXA2 | annexin A2 | 0.307 | |
PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.304 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
S100a8 | S100 calcium binding protein A8 | 0.147 | |
S100a9 | S100 calcium binding protein A9 | 0.121 | |
Pdia6 | protein disulfide isomerase family A, member 6 | 0.067 | |
Eif3f | eukaryotic translation initiation factor 3, subunit F | 0.039 | |
Smad7 | SMAD family member 7 | 0.036 | |
Akr1a1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.034 | |
Cdk4 | cyclin-dependent kinase 4 | 0.031 | |
Tcf12 | transcription factor 12 | 0.030 | |
Prkacb | protein kinase, cAMP dependent, catalytic, beta | 0.027 | |
Ppib | peptidylprolyl isomerase B | 0.027 | |
Socs3 | suppressor of cytokine signaling 3 | 0.024 | |
Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.022 | |
Rps3 | ribosomal protein S3 | 0.022 | |
Lig3 | ligase III, DNA, ATP-dependent | 0.021 | |
Pdia4 | protein disulfide isomerase family A, member 4 | 0.020 | |
Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.020 | |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.019 | |
Rnf4 | ring finger protein 4 | 0.019 | |
Cish | cytokine inducible SH2-containing protein | 0.018 | |
Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.017 | |
B4galt1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.016 | |
Ralgds | ral guanine nucleotide dissociation stimulator | 0.016 | |
Cd14 | CD14 molecule | 0.016 | |
Myo1b | myosin Ib | 0.016 | |
Prrx1 | paired related homeobox 1 | 0.015 | |
Ugt1a6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.015 | |
Casp3 | caspase 3 | 0.015 | |
Creb1 | cAMP responsive element binding protein 1 | 0.014 | |
Il1r2 | interleukin 1 receptor, type II | 0.014 | |
Dctn4 | dynactin 4 | 0.014 | |
Trim23 | tripartite motif-containing 23 | 0.013 | |
Csnk1g3 | casein kinase 1, gamma 3 | 0.012 | |
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.012 | |
Epn1 | Epsin 1 | 0.012 | |
Rpn2 | ribophorin II | 0.011 | |
Jun | Jun oncogene | 0.011 | |
Pkia | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.011 | |
Pgcp | plasma glutamate carboxypeptidase | 0.011 | |
Litaf | lipopolysaccharide-induced TNF factor | 0.011 | |
Icam1 | intercellular adhesion molecule 1 | 0.010 | |
Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.010 |