IMP

Process View

Homo sapiens

21 genes annotated in human

gliogenesis

GO:0042063

The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gliogenesis"

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Name	Description	Probability	Func Analog Organism
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.971
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.960
FYN	FYN oncogene related to SRC, FGR, YES	0.945
NCF1	neutrophil cytosolic factor 1	0.941
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.913
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.858	Mouse Rat
EGFR	epidermal growth factor receptor	0.837
NOTCH1	notch 1	0.780	Zebrafish Mouse Rat Fly
PRKCA	protein kinase C, alpha	0.595	Human
YAP1	Yes-associated protein 1	0.567	Fly
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.346
POU5F1	POU class 5 homeobox 1	0.329
BCAR1	breast cancer anti-estrogen resistance 1	0.273
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.251
FGF1	fibroblast growth factor 1 (acidic)	0.248
CCR5	chemokine (C-C motif) receptor 5	0.238
GRB2	growth factor receptor-bound protein 2	0.233
TCF4	transcription factor 4	0.233
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.209
JAG1	jagged 1	0.201	Fly
HDAC1	histone deacetylase 1	0.197	Zebrafish Mouse Rat
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.187
POU3F2	POU class 3 homeobox 2	0.185	Mouse
NCF4	neutrophil cytosolic factor 4, 40kDa	0.184
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.171
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.159
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.158
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.156
NCOR2	nuclear receptor corepressor 2	0.155
LAT	linker for activation of T cells	0.153
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.124
DNM1	dynamin 1	0.117
NOTCH3	notch 3	0.114	Zebrafish Fly
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.113
ACTB	actin, beta	0.110
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.103
ATXN1	ataxin 1	0.102	Mouse
FGFR1	fibroblast growth factor receptor 1	0.098	Fly
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.098
SMAD4	SMAD family member 4	0.097
CCL5	chemokine (C-C motif) ligand 5	0.097	Human
OLIG2	oligodendrocyte lineage transcription factor 2	0.097	Zebrafish Mouse
NCF2	neutrophil cytosolic factor 2	0.094
IL1R1	interleukin 1 receptor, type I	0.092
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.088
ESR1	estrogen receptor 1	0.088
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.087	Zebrafish Mouse Rat
SRGN	serglycin	0.085
PAX3	paired box 3	0.076
C1R	complement component 1, r subcomponent	0.075
RUNX1	runt-related transcription factor 1	0.073
SOX10	SRY (sex determining region Y)-box 10	0.072	Human Mouse
CCL4	chemokine (C-C motif) ligand 4	0.068	Human
SMAD7	SMAD family member 7	0.066
EPAS1	endothelial PAS domain protein 1	0.062
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.060	Mouse
CYBA	cytochrome b-245, alpha polypeptide	0.059
SNAI1	snail homolog 1 (Drosophila)	0.059
PRKCD	protein kinase C, delta	0.057	Human
ALB	albumin	0.057
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.057
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.056
EP300	E1A binding protein p300	0.055
BMPR1A	bone morphogenetic protein receptor, type IA	0.054
ENO1	enolase 1, (alpha)	0.054
AMPH	amphiphysin	0.054	Human
PTCH1	patched 1	0.052
CCL2	chemokine (C-C motif) ligand 2	0.049
EGR1	early growth response 1	0.047	Rat
RHOA	ras homolog gene family, member A	0.047	Mouse Fly
DRD2	dopamine receptor D2	0.047
FSTL1	follistatin-like 1	0.046
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.046
BMP7	bone morphogenetic protein 7	0.045
GAB1	GRB2-associated binding protein 1	0.045
EGR3	early growth response 3	0.043
MYOD1	myogenic differentiation 1	0.042
SIRT1	sirtuin 1	0.042
MED28	mediator complex subunit 28	0.041
SCHIP1	schwannomin interacting protein 1	0.041
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.041
TGFB3	transforming growth factor, beta 3	0.040
INADL	InaD-like (Drosophila)	0.040
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.040
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.040
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.040
CUL1	cullin 1	0.039
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.039	Mouse
EIF2B5	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	0.038
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.038	Mouse
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.037
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.037	Rat
STK4	serine/threonine kinase 4	0.037
EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	0.036
MAP2	microtubule-associated protein 2	0.036
MSX1	msh homeobox 1	0.036	Fly
TRIM9	tripartite motif containing 9	0.035
FN1	fibronectin 1	0.035	Rat
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.035
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.035	Fly
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.034	Fly
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.033
SMAD3	SMAD family member 3	0.033
IGF1R	insulin-like growth factor 1 receptor	0.033
EZR	ezrin	0.031	Human
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.031
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.031
GLIS2	GLIS family zinc finger 2	0.030
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.030
CD44	CD44 molecule (Indian blood group)	0.029
SOX21	SRY (sex determining region Y)-box 21	0.029
APC	adenomatous polyposis coli	0.029
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.029
SH3KBP1	SH3-domain kinase binding protein 1	0.029
PRKCG	protein kinase C, gamma	0.028	Human
TNRC6A	trinucleotide repeat containing 6A	0.028
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.028
AMOTL1	angiomotin like 1	0.027
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.027
FERMT2	fermitin family member 2	0.027
PICK1	protein interacting with PRKCA 1	0.027	Rat
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.026
TJP2	tight junction protein 2 (zona occludens 2)	0.026
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.026
AXIN1	axin 1	0.026
AMOTL2	angiomotin like 2	0.025
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.025
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.025
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.025
GFAP	glial fibrillary acidic protein	0.025	Mouse Rat
SOX2	SRY (sex determining region Y)-box 2	0.024	Human
SPRY2	sprouty homolog 2 (Drosophila)	0.024	Fly
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.024	Rat
EGR2	early growth response 2	0.024	Zebrafish Mouse
CXCL10	chemokine (C-X-C motif) ligand 10	0.023
CCND1	cyclin D1	0.023
APP	amyloid beta (A4) precursor protein	0.023
NFIB	nuclear factor I/B	0.023	Mouse
HDAC6	histone deacetylase 6	0.023
ARHGAP1	Rho GTPase activating protein 1	0.022
AHR	aryl hydrocarbon receptor	0.022
MPDZ	multiple PDZ domain protein	0.022
DTNA	dystrobrevin, alpha	0.022
ATXN7L3	ataxin 7-like 3	0.022	Fly
TESK1	testis-specific kinase 1	0.022
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.022
SORBS2	sorbin and SH3 domain containing 2	0.022
MEOX2	mesenchyme homeobox 2	0.022
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.022
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.021
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.021
PLAU	plasminogen activator, urokinase	0.021
HIST1H3B	histone cluster 1, H3b	0.021
JAK1	Janus kinase 1	0.021
JAM2	junctional adhesion molecule 2	0.020
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.020
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.020	Zebrafish Mouse
MAPT	microtubule-associated protein tau	0.019
CADM1	cell adhesion molecule 1	0.019
SFRP1	secreted frizzled-related protein 1	0.019
WEE1	WEE1 homolog (S. pombe)	0.018
JAK2	Janus kinase 2	0.018
CALD1	caldesmon 1	0.018
DLL1	delta-like 1 (Drosophila)	0.018	Fly
COL2A1	collagen, type II, alpha 1	0.018
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.018
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.018
SMAD1	SMAD family member 1	0.018
TBX2	T-box 2	0.017
BOP1	block of proliferation 1	0.017
IL6	interleukin 6 (interferon, beta 2)	0.017
NOTCH2	notch 2	0.017	Fly
TGFB2	transforming growth factor, beta 2	0.017
CCNE1	cyclin E1	0.017
CXCR5	chemokine (C-X-C motif) receptor 5	0.017
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.017
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.016
MYH9	myosin, heavy chain 9, non-muscle	0.016
CDK4	cyclin-dependent kinase 4	0.016	Human
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	0.016
PRKCB	protein kinase C, beta	0.016	Human
PARVA	parvin, alpha	0.016
CDK6	cyclin-dependent kinase 6	0.016
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.016
PLAT	plasminogen activator, tissue	0.016
FBLN1	fibulin 1	0.016
FAM46A	family with sequence similarity 46, member A	0.015
BTRC	beta-transducin repeat containing	0.015	Fly
CCL3	chemokine (C-C motif) ligand 3	0.015	Human Mouse
CXCL12	chemokine (C-X-C motif) ligand 12	0.015
PAX8	paired box 8	0.015
MSN	moesin	0.015	Human
QKI	quaking homolog, KH domain RNA binding (mouse)	0.015	Fly
HDAC2	histone deacetylase 2	0.015	Mouse
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.015
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.015
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.015
KDM1A	lysine (K)-specific demethylase 1A	0.015
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015	Mouse
GFI1B	growth factor independent 1B transcription repressor	0.015
E2F1	E2F transcription factor 1	0.015
MYO10	myosin X	0.015
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.015
CXCL3	chemokine (C-X-C motif) ligand 3	0.015
AR	androgen receptor	0.014
VTN	vitronectin	0.014
CSNK2B	casein kinase 2, beta polypeptide	0.014
GATA2	GATA binding protein 2	0.014
PRTN3	proteinase 3	0.014	Human
VCL	vinculin	0.014
PLCG1	phospholipase C, gamma 1	0.014
TP73	tumor protein p73	0.014	Rat
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.014
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.014
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.014	Rat
POU3F3	POU class 3 homeobox 3	0.014
PTK2	PTK2 protein tyrosine kinase 2	0.014	Rat
NOXA1	NADPH oxidase activator 1	0.014
SOX11	SRY (sex determining region Y)-box 11	0.013
PDGFC	platelet derived growth factor C	0.013
ARID1A	AT rich interactive domain 1A (SWI-like)	0.013
IQGAP1	IQ motif containing GTPase activating protein 1	0.013
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.013
TRIP6	thyroid hormone receptor interactor 6	0.013
ACCN2	amiloride-sensitive cation channel 2, neuronal	0.013
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.013
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.013
UTRN	utrophin	0.013
PBX1	pre-B-cell leukemia homeobox 1	0.013
ICAM1	intercellular adhesion molecule 1	0.013
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.013
AMOT	angiomotin	0.013
SLIT2	slit homolog 2 (Drosophila)	0.013	Fly
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
F3	coagulation factor III (thromboplastin, tissue factor)	0.013
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.013
WNT3A	wingless-type MMTV integration site family, member 3A	0.013
DPP4	dipeptidyl-peptidase 4	0.013
TJP1	tight junction protein 1 (zona occludens 1)	0.013
TNRC6B	trinucleotide repeat containing 6B	0.012
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.012
JUP	junction plakoglobin	0.012
SOCS3	suppressor of cytokine signaling 3	0.012
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.012
PTBP1	polypyrimidine tract binding protein 1	0.012
IGFBP3	insulin-like growth factor binding protein 3	0.012
SRCIN1	SRC kinase signaling inhibitor 1	0.012
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.012
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.012
SOX9	SRY (sex determining region Y)-box 9	0.012	Human Zebrafish Mouse
FOXG1	forkhead box G1	0.012
TP53BP2	tumor protein p53 binding protein, 2	0.012
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.012
MEIS2	Meis homeobox 2	0.012
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012	Mouse
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.012
MSX2	msh homeobox 2	0.012	Fly
SYNJ1	synaptojanin 1	0.012	Rat
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.012
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.012
NFIA	nuclear factor I/A	0.012
IGFBP5	insulin-like growth factor binding protein 5	0.012
ALK	anaplastic lymphoma receptor tyrosine kinase	0.012
SIX3	SIX homeobox 3	0.012
CXCL9	chemokine (C-X-C motif) ligand 9	0.012
JAM3	junctional adhesion molecule 3	0.011
CNTN2	contactin 2 (axonal)	0.011	Mouse Fly
SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	0.011	Fly
TARBP2	TAR (HIV-1) RNA binding protein 2	0.011
SIX6	SIX homeobox 6	0.011
SH3GL2	SH3-domain GRB2-like 2	0.011
BDNF	brain-derived neurotrophic factor	0.011
BHLHE40	basic helix-loop-helix family, member e40	0.011
ADORA1	adenosine A1 receptor	0.011
RAX	retina and anterior neural fold homeobox	0.011
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.011
C1QL1	complement component 1, q subcomponent-like 1	0.011
FBXW2	F-box and WD repeat domain containing 2	0.011
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.011
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.011	Mouse
CCR1	chemokine (C-C motif) receptor 1	0.011
F11R	F11 receptor	0.011
CREBBP	CREB binding protein	0.011
TNRC6C	trinucleotide repeat containing 6C	0.011
EIF2B2	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	0.011
BMP2	bone morphogenetic protein 2	0.011	Mouse
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.011
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.011
THBS1	thrombospondin 1	0.010
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.010
NPAS3	neuronal PAS domain protein 3	0.010
LHX2	LIM homeobox 2	0.010
NKX2-2	NK2 homeobox 2	0.010	Zebrafish Mouse
TPM4	tropomyosin 4	0.010
TGFBR1	transforming growth factor, beta receptor 1	0.010
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.010
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.010	Mouse
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.010
LIFR	leukemia inhibitory factor receptor alpha	0.010
RHOC	ras homolog gene family, member C	0.010	Fly
MARCKSL1	MARCKS-like 1	0.010
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.010
IDE	insulin-degrading enzyme	0.010
ITSN1	intersectin 1 (SH3 domain protein)	0.010
MAP2K1	mitogen-activated protein kinase kinase 1	0.010
MAML1	mastermind-like 1 (Drosophila)	0.010
CCR7	chemokine (C-C motif) receptor 7	0.010