IMP

Process View

Homo sapiens

33 genes annotated in human

polysaccharide metabolic process

The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "polysaccharide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "polysaccharide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000	Human
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.991	Yeast
INSR	insulin receptor	0.990
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.958	Yeast
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.924
NUMB	numb homolog (Drosophila)	0.913
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.825
EGFR	epidermal growth factor receptor	0.823
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.722
GSK3B	glycogen synthase kinase 3 beta	0.694
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.515
VEGFA	vascular endothelial growth factor A	0.510	Human
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.479
NCF1	neutrophil cytosolic factor 1	0.479
GRB10	growth factor receptor-bound protein 10	0.429	Rat
AR	androgen receptor	0.405
NOXA1	NADPH oxidase activator 1	0.384
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.375
RXRA	retinoid X receptor, alpha	0.350
IRS1	insulin receptor substrate 1	0.331
BCL3	B-cell CLL/lymphoma 3	0.322
IRS2	insulin receptor substrate 2	0.314
NRP1	neuropilin 1	0.310
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.305
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.293
HIPK2	homeodomain interacting protein kinase 2	0.284
ALDOA	aldolase A, fructose-bisphosphate	0.248
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.240
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.227
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.217
LZTS2	leucine zipper, putative tumor suppressor 2	0.212
HIP1	huntingtin interacting protein 1	0.186
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.174
PRKCZ	protein kinase C, zeta	0.172	Human
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.152
APP	amyloid beta (A4) precursor protein	0.138
IGF1R	insulin-like growth factor 1 receptor	0.137	Human
HTT	huntingtin	0.131
KAT2B	K(lysine) acetyltransferase 2B	0.130
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.121
HYOU1	hypoxia up-regulated 1	0.117
ITGB1BP3	integrin beta 1 binding protein 3	0.115
VCP	valosin containing protein	0.106
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.102	Yeast
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.101
CNTF	ciliary neurotrophic factor	0.096
GYS1	glycogen synthase 1 (muscle)	0.095
PRKCA	protein kinase C, alpha	0.087
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.087
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.085
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.082
IGF2R	insulin-like growth factor 2 receptor	0.082
SH3RF1	SH3 domain containing ring finger 1	0.082
AXIN1	axin 1	0.079
DCAF7	DDB1 and CUL4 associated factor 7	0.079
MAPT	microtubule-associated protein tau	0.075
TGFB3	transforming growth factor, beta 3	0.072
GYG1	glycogenin 1	0.068	Yeast
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.065
ENG	endoglin	0.063
HR	hairless homolog (mouse)	0.063
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.062
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.062	Human
SIRT1	sirtuin 1	0.062
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.060	Human
SMAD2	SMAD family member 2	0.055
LDLR	low density lipoprotein receptor	0.055
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.055
RARA	retinoic acid receptor, alpha	0.054
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.054
LRRK2	leucine-rich repeat kinase 2	0.053
BTRC	beta-transducin repeat containing	0.052
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.050
FAF1	Fas (TNFRSF6) associated factor 1	0.049
TNIP2	TNFAIP3 interacting protein 2	0.048
GYG2	glycogenin 2	0.045	Yeast
RAB6A	RAB6A, member RAS oncogene family	0.043
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.043
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.041
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.040
CREBBP	CREB binding protein	0.040
PRKCB	protein kinase C, beta	0.039
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.039
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.038
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.038
BCL10	B-cell CLL/lymphoma 10	0.037
CCND1	cyclin D1	0.036
CCND3	cyclin D3	0.035
UBQLN1	ubiquilin 1	0.035
STAT5B	signal transducer and activator of transcription 5B	0.035
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.035
LYPLA1	lysophospholipase I	0.035
NCOA1	nuclear receptor coactivator 1	0.034
MED25	mediator complex subunit 25	0.034
RUNX1	runt-related transcription factor 1	0.034
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.034
CLTC	clathrin, heavy chain (Hc)	0.034
GBAS	glioblastoma amplified sequence	0.033
NCOR2	nuclear receptor corepressor 2	0.033
FSTL1	follistatin-like 1	0.033
CAPRIN2	caprin family member 2	0.033
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.032
PGF	placental growth factor	0.031	Human
RPTOR	regulatory associated protein of MTOR, complex 1	0.031
GCKR	glucokinase (hexokinase 4) regulator	0.031
OSBP	oxysterol binding protein	0.031
GOLGA8B	golgin A8 family, member B	0.031
ATXN3	ataxin 3	0.031
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.031
TOM1L1	target of myb1 (chicken)-like 1	0.031
HDAC3	histone deacetylase 3	0.031
PRKCD	protein kinase C, delta	0.029	Human
PGK1	phosphoglycerate kinase 1	0.029
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.028
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.028
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.027
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.027
PDGFC	platelet derived growth factor C	0.027
FHL2	four and a half LIM domains 2	0.027
SP3	Sp3 transcription factor	0.026
IL6R	interleukin 6 receptor	0.026
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.026
CREB1	cAMP responsive element binding protein 1	0.026
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.026
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.026
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.025
PICK1	protein interacting with PRKCA 1	0.025
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.025
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.025	Human
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.024
PDGFA	platelet-derived growth factor alpha polypeptide	0.024	Human
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.024
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.023
TRIM9	tripartite motif containing 9	0.023
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.023
PDPK1	3-phosphoinositide dependent protein kinase-1	0.023
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.022
PPP5C	protein phosphatase 5, catalytic subunit	0.022
OCRL	oculocerebrorenal syndrome of Lowe	0.022	Human
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.022
MBL2	mannose-binding lectin (protein C) 2, soluble	0.022
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.021	Human
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.021	Human
GYS2	glycogen synthase 2 (liver)	0.021
SFN	stratifin	0.021	Yeast
ACACA	acetyl-CoA carboxylase alpha	0.021
SH2B1	SH2B adaptor protein 1	0.021
SH2D2A	SH2 domain containing 2A	0.020
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.020
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.020
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.020
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.020
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.020
SESN2	sestrin 2	0.020
UBXN2A	UBX domain protein 2A	0.019
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.019
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.019
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.019
FBXW11	F-box and WD repeat domain containing 11	0.018
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.018
CDCP1	CUB domain containing protein 1	0.018
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.018
TGFBR1	transforming growth factor, beta receptor 1	0.018
LRP6	low density lipoprotein receptor-related protein 6	0.018	Human
SORBS3	sorbin and SH3 domain containing 3	0.018
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.018
HIC1	hypermethylated in cancer 1	0.017
PSEN1	presenilin 1	0.017
HDAC4	histone deacetylase 4	0.017
TNIK	TRAF2 and NCK interacting kinase	0.017
CSK	c-src tyrosine kinase	0.017
CSDE1	cold shock domain containing E1, RNA-binding	0.017
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.017
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.017
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.017
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.017
ZNF746	zinc finger protein 746	0.017
HNF4A	hepatocyte nuclear factor 4, alpha	0.016
CDK5	cyclin-dependent kinase 5	0.016
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.016
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.016
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.016
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.016
TM9SF4	transmembrane 9 superfamily protein member 4	0.016
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.016
EP300	E1A binding protein p300	0.016
CDH5	cadherin 5, type 2 (vascular endothelium)	0.016
SRP9	signal recognition particle 9kDa	0.016
WSB1	WD repeat and SOCS box containing 1	0.016
TM9SF3	transmembrane 9 superfamily member 3	0.016
CDK6	cyclin-dependent kinase 6	0.016
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.016
PILRA	paired immunoglobin-like type 2 receptor alpha	0.016
TGFBR3	transforming growth factor, beta receptor III	0.016
FCHO2	FCH domain only 2	0.016
TF	transferrin	0.015
SAMD4B	sterile alpha motif domain containing 4B	0.015
SORBS2	sorbin and SH3 domain containing 2	0.015
PLD3	phospholipase D family, member 3	0.015
NCOR1	nuclear receptor corepressor 1	0.015
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.015
SH2D1A	SH2 domain containing 1A	0.015
RAB8A	RAB8A, member RAS oncogene family	0.015
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.015
OPTN	optineurin	0.015
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.015
CYBA	cytochrome b-245, alpha polypeptide	0.015
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.015	Yeast
FYN	FYN oncogene related to SRC, FGR, YES	0.015
SRSF5	serine/arginine-rich splicing factor 5	0.015
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.015
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.014
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.014
DERL1	Der1-like domain family, member 1	0.014
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.014
CD2	CD2 molecule	0.014
SIRT2	sirtuin 2	0.014
COL4A2	collagen, type IV, alpha 2	0.014
INPPL1	inositol polyphosphate phosphatase-like 1	0.014
TSC2	tuberous sclerosis 2	0.014
ACVR1B	activin A receptor, type IB	0.014
TMEM123	transmembrane protein 123	0.014
PNPLA2	patatin-like phospholipase domain containing 2	0.014
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.014
HMOX2	heme oxygenase (decycling) 2	0.014
S100A1	S100 calcium binding protein A1	0.014
TUBA1A	tubulin, alpha 1a	0.014
PTPRB	protein tyrosine phosphatase, receptor type, B	0.014
IL4R	interleukin 4 receptor	0.014
STAT2	signal transducer and activator of transcription 2, 113kDa	0.013
CCL14	chemokine (C-C motif) ligand 14	0.013
NCOA2	nuclear receptor coactivator 2	0.013
CD247	CD247 molecule	0.013
BIN1	bridging integrator 1	0.013
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.013
KIF1C	kinesin family member 1C	0.013
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.013	Rat
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.013
GRB14	growth factor receptor-bound protein 14	0.013
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.013
CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	0.013
NCOA6	nuclear receptor coactivator 6	0.013
ACVR2B	activin A receptor, type IIB	0.013
JAG1	jagged 1	0.013
MYO1C	myosin IC	0.013
ZFPM1	zinc finger protein, multitype 1	0.013
BMP2	bone morphogenetic protein 2	0.013
C20orf43	chromosome 20 open reading frame 43	0.013
STC1	stanniocalcin 1	0.013
COL2A1	collagen, type II, alpha 1	0.012
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.012
EXT1	exostosin 1	0.012
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.012
PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F	0.012
GMCL1	germ cell-less homolog 1 (Drosophila)	0.012
PLCG1	phospholipase C, gamma 1	0.012
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.012
CSNK2B	casein kinase 2, beta polypeptide	0.012
PPP4R1	protein phosphatase 4, regulatory subunit 1	0.012
CTBP2	C-terminal binding protein 2	0.012
GLTPD1	glycolipid transfer protein domain containing 1	0.012
DEFA1	defensin, alpha 1	0.012
TEF	thyrotrophic embryonic factor	0.012
HCFC1	host cell factor C1 (VP16-accessory protein)	0.012
AXIN2	axin 2	0.012
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.012
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.012
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.011
FST	follistatin	0.011
PKM2	pyruvate kinase, muscle	0.011
NMT2	N-myristoyltransferase 2	0.011
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.011
ADAP1	ArfGAP with dual PH domains 1	0.011
BICD1	bicaudal D homolog 1 (Drosophila)	0.011
DEPTOR	DEP domain containing MTOR-interacting protein	0.011
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
NIN	ninein (GSK3B interacting protein)	0.011
DLG1	discs, large homolog 1 (Drosophila)	0.011
CCND2	cyclin D2	0.011
FHOD3	formin homology 2 domain containing 3	0.011
PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.011
MAP2K5	mitogen-activated protein kinase kinase 5	0.011
DDIT4	DNA-damage-inducible transcript 4	0.011
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.011
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.011
DCN	decorin	0.011
OSMR	oncostatin M receptor	0.011
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.011
LCK	lymphocyte-specific protein tyrosine kinase	0.011
PRKCSH	protein kinase C substrate 80K-H	0.011
EPAS1	endothelial PAS domain protein 1	0.011
ISOC1	isochorismatase domain containing 1	0.011
PRR5	proline rich 5 (renal)	0.011
KDM6B	lysine (K)-specific demethylase 6B	0.011
SGSH	N-sulfoglucosamine sulfohydrolase	0.011
MBNL1	muscleblind-like (Drosophila)	0.011
POFUT1	protein O-fucosyltransferase 1	0.011
MAP1B	microtubule-associated protein 1B	0.011
MARK2	MAP/microtubule affinity-regulating kinase 2	0.011
BMX	BMX non-receptor tyrosine kinase	0.011
RAB3A	RAB3A, member RAS oncogene family	0.010
JAK1	Janus kinase 1	0.010
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.010
NOV	nephroblastoma overexpressed gene	0.010
FAM117B	family with sequence similarity 117, member B	0.010
IGFBP3	insulin-like growth factor binding protein 3	0.010
FNDC3B	fibronectin type III domain containing 3B	0.010
PYGM	phosphorylase, glycogen, muscle	0.010	Rat
WNT3A	wingless-type MMTV integration site family, member 3A	0.010
TUBB4	tubulin, beta 4	0.010
DDR2	discoidin domain receptor tyrosine kinase 2	0.010
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.010
MAP2K3	mitogen-activated protein kinase kinase 3	0.010
GOLPH3	golgi phosphoprotein 3 (coat-protein)	0.010
JUP	junction plakoglobin	0.010
PFKL	phosphofructokinase, liver	0.010
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.010
TBC1D9B	TBC1 domain family, member 9B (with GRAM domain)	0.010
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.010
TEK	TEK tyrosine kinase, endothelial	0.010
S100A2	S100 calcium binding protein A2	0.010
TGFA	transforming growth factor, alpha	0.010
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.010
THBS1	thrombospondin 1	0.010
EPN1	epsin 1	0.010
FOXO4	forkhead box O4	0.010
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.010
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.010
RAB5A	RAB5A, member RAS oncogene family	0.010