IMP

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Homo sapiens

39 genes annotated in human

protein deacylation

The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein deacylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein deacylation" (in gray)

Name	Description	Probability	Func Analog Organism
HDAC1	histone deacetylase 1	0.995
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.995
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.989
MAPK14	mitogen-activated protein kinase 14	0.972	Human
NCOR2	nuclear receptor corepressor 2	0.966
SMAD4	SMAD family member 4	0.959
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.941
RB1	retinoblastoma 1	0.939
TGIF1	TGFB-induced factor homeobox 1	0.914
HDAC2	histone deacetylase 2	0.903
KDM1A	lysine (K)-specific demethylase 1A	0.900
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.820
NCOR1	nuclear receptor corepressor 1	0.807	Mouse
NRP1	neuropilin 1	0.779
JUN	jun proto-oncogene	0.753
CREBBP	CREB binding protein	0.733	Human
VEGFA	vascular endothelial growth factor A	0.723
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.703
MRFAP1	Morf4 family associated protein 1	0.676
HDAC3	histone deacetylase 3	0.661
ATF2	activating transcription factor 2	0.660
EP300	E1A binding protein p300	0.629
MTA3	metastasis associated 1 family, member 3	0.620
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.561
MAP2K4	mitogen-activated protein kinase kinase 4	0.514
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.500	Fly
HDAC4	histone deacetylase 4	0.499
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.437
CHD4	chromodomain helicase DNA binding protein 4	0.408
SIRT1	sirtuin 1	0.346
DCAF7	DDB1 and CUL4 associated factor 7	0.333
HIPK2	homeodomain interacting protein kinase 2	0.331
ENG	endoglin	0.307
ESR1	estrogen receptor 1	0.306
SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.270
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.267
HDAC6	histone deacetylase 6	0.260
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.254
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.242
MORF4L1	mortality factor 4 like 1	0.230
MORF4L2	mortality factor 4 like 2	0.227	Human Yeast
BRMS1	breast cancer metastasis suppressor 1	0.220
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.218
CUX1	cut-like homeobox 1	0.211
MTA1	metastasis associated 1	0.210
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.194
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.189
RCOR1	REST corepressor 1	0.186
HDAC7	histone deacetylase 7	0.168	Human Fly
RBBP4	retinoblastoma binding protein 4	0.166
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.165
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.156
HDAC5	histone deacetylase 5	0.153
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.151
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.151
MEF2C	myocyte enhancer factor 2C	0.148
ADRBK1	adrenergic, beta, receptor kinase 1	0.121
SIRT3	sirtuin 3	0.121
CTBP1	C-terminal binding protein 1	0.119
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.118
ATF3	activating transcription factor 3	0.107
RUNX1	runt-related transcription factor 1	0.105
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.100
ARRB1	arrestin, beta 1	0.099
PGF	placental growth factor	0.095	Human
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.085
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.082
STAG2	stromal antigen 2	0.080
KIAA0182	KIAA0182	0.077
TSC22D1	TSC22 domain family, member 1	0.072
CHD3	chromodomain helicase DNA binding protein 3	0.072
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.071
CDR2	cerebellar degeneration-related protein 2, 62kDa	0.071
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.071
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.070
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.066
C16orf70	chromosome 16 open reading frame 70	0.066
PDGFC	platelet derived growth factor C	0.063
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.061
CUL7	cullin 7	0.060
PHF21A	PHD finger protein 21A	0.059
SETD7	SET domain containing (lysine methyltransferase) 7	0.058
AHR	aryl hydrocarbon receptor	0.057
CPNE6	copine VI (neuronal)	0.054
THRAP3	thyroid hormone receptor associated protein 3	0.054
TOP1	topoisomerase (DNA) I	0.053
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.053
MAPK3	mitogen-activated protein kinase 3	0.053
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.052
PML	promyelocytic leukemia	0.051
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.050
MED15	mediator complex subunit 15	0.050
TBL1X	transducin (beta)-like 1X-linked	0.049	Fly
SIRT2	sirtuin 2	0.048
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.048
HDAC9	histone deacetylase 9	0.047
SS18	synovial sarcoma translocation, chromosome 18	0.046
HSPA1L	heat shock 70kDa protein 1-like	0.046
ZNF217	zinc finger protein 217	0.045
MYST1	MYST histone acetyltransferase 1	0.044
NONO	non-POU domain containing, octamer-binding	0.043
ADNP	activity-dependent neuroprotector homeobox	0.043
PCDH9	protocadherin 9	0.042
PLCG1	phospholipase C, gamma 1	0.042
MBD3	methyl-CpG binding domain protein 3	0.041
KDM2A	lysine (K)-specific demethylase 2A	0.040
SNAI1	snail homolog 1 (Drosophila)	0.040	Fly
SIRT5	sirtuin 5	0.040
HMG20A	high mobility group 20A	0.040
KDM5B	lysine (K)-specific demethylase 5B	0.040
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.039
PRKCA	protein kinase C, alpha	0.039
COL4A1	collagen, type IV, alpha 1	0.039
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.038
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.038
RARA	retinoic acid receptor, alpha	0.038
MAPK8	mitogen-activated protein kinase 8	0.037
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.036
TGFBR1	transforming growth factor, beta receptor 1	0.036
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.036
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.036
SKIL	SKI-like oncogene	0.035
NCOA6	nuclear receptor coactivator 6	0.035
ZMYM2	zinc finger, MYM-type 2	0.034
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.033
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.033
FBXO11	F-box protein 11	0.033
MBD2	methyl-CpG binding domain protein 2	0.032
TP53BP2	tumor protein p53 binding protein, 2	0.032
PBRM1	polybromo 1	0.031
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.031
COL6A1	collagen, type VI, alpha 1	0.030
PKN2	protein kinase N2	0.030
CTTN	cortactin	0.030
PKN1	protein kinase N1	0.030
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.030
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.030
TGFB3	transforming growth factor, beta 3	0.030
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.029
E2F3	E2F transcription factor 3	0.029
TRIM11	tripartite motif containing 11	0.029
MAGEA2	melanoma antigen family A, 2	0.028
DAXX	death-domain associated protein	0.028
OBSL1	obscurin-like 1	0.028
FAM117B	family with sequence similarity 117, member B	0.028
STAG1	stromal antigen 1	0.027
MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)	0.027
SP1	Sp1 transcription factor	0.027
RSF1	remodeling and spacing factor 1	0.027
FSTL1	follistatin-like 1	0.027
PIAS2	protein inhibitor of activated STAT, 2	0.026
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.026
MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	0.026
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.025
ETV6	ets variant 6	0.025
EPC2	enhancer of polycomb homolog 2 (Drosophila)	0.025
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.024
DUSP1	dual specificity phosphatase 1	0.024
PURA	purine-rich element binding protein A	0.024
DICER1	dicer 1, ribonuclease type III	0.023
NRIP1	nuclear receptor interacting protein 1	0.023
GATAD2B	GATA zinc finger domain containing 2B	0.023
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.022
HSF1	heat shock transcription factor 1	0.022
USP17	ubiquitin specific peptidase 17	0.022
TUBA1A	tubulin, alpha 1a	0.022
OSGEP	O-sialoglycoprotein endopeptidase	0.022
MSL2	male-specific lethal 2 homolog (Drosophila)	0.022
EGR1	early growth response 1	0.022
ZMYM3	zinc finger, MYM-type 3	0.022
GORASP1	golgi reassembly stacking protein 1, 65kDa	0.022
MAPK15	mitogen-activated protein kinase 15	0.022
BCL6	B-cell CLL/lymphoma 6	0.021	Mouse
USF2	upstream transcription factor 2, c-fos interacting	0.021
MAPK12	mitogen-activated protein kinase 12	0.021	Human
HDAC11	histone deacetylase 11	0.021
PHF12	PHD finger protein 12	0.021
CCDC101	coiled-coil domain containing 101	0.021
RBBP8	retinoblastoma binding protein 8	0.020
GATAD2A	GATA zinc finger domain containing 2A	0.020
RFX7	regulatory factor X, 7	0.020
ZBTB16	zinc finger and BTB domain containing 16	0.020
MRFAP1L1	Morf4 family associated protein 1-like 1	0.020
HES1	hairy and enhancer of split 1, (Drosophila)	0.020
KAT2B	K(lysine) acetyltransferase 2B	0.020
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.019
SOX13	SRY (sex determining region Y)-box 13	0.019
FKBP4	FK506 binding protein 4, 59kDa	0.019
SIRT4	sirtuin 4	0.019	Mouse
JUB	jub, ajuba homolog (Xenopus laevis)	0.019
UBXN7	UBX domain protein 7	0.019
PPARA	peroxisome proliferator-activated receptor alpha	0.019
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.019
SOCS3	suppressor of cytokine signaling 3	0.019
SAFB	scaffold attachment factor B	0.019
RREB1	ras responsive element binding protein 1	0.018
IKZF4	IKAROS family zinc finger 4 (Eos)	0.018
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.018
CUL9	cullin 9	0.018
HUWE1	HECT, UBA and WWE domain containing 1	0.018
JUND	jun D proto-oncogene	0.018
SAMD3	sterile alpha motif domain containing 3	0.018
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.018	Mouse
SAP25	sin3A-binding protein 25	0.018
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.017
IPO13	importin 13	0.017
TGFB2	transforming growth factor, beta 2	0.017
THBS1	thrombospondin 1	0.017
CDK6	cyclin-dependent kinase 6	0.017
SCAF8	SR-related CTD-associated factor 8	0.017
MED13L	mediator complex subunit 13-like	0.017
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.017
MIER1	mesoderm induction early response 1 homolog (Xenopus laevis)	0.017
KDM3B	lysine (K)-specific demethylase 3B	0.017
FOXO3	forkhead box O3	0.017
RYK	RYK receptor-like tyrosine kinase	0.017
PTPRB	protein tyrosine phosphatase, receptor type, B	0.017
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.017
CDK17	cyclin-dependent kinase 17	0.017
IRS2	insulin receptor substrate 2	0.016
ZNF148	zinc finger protein 148	0.016
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.016
XPO7	exportin 7	0.016
TARBP2	TAR (HIV-1) RNA binding protein 2	0.016
DUSP6	dual specificity phosphatase 6	0.016
MEF2A	myocyte enhancer factor 2A	0.016
PUM2	pumilio homolog 2 (Drosophila)	0.016
FRK	fyn-related kinase	0.016
MT1A	metallothionein 1A	0.016
RCOR2	REST corepressor 2	0.016	Human
LZTS2	leucine zipper, putative tumor suppressor 2	0.016
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.016
SRRM2	serine/arginine repetitive matrix 2	0.016
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.016	Mouse
SGSM2	small G protein signaling modulator 2	0.015
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.015
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.015
RICTOR	RPTOR independent companion of MTOR, complex 2	0.015
ATM	ataxia telangiectasia mutated	0.015
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.015
AR	androgen receptor	0.015
CDYL	chromodomain protein, Y-like	0.015
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.015
TPM3	tropomyosin 3	0.015
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.015
E2F2	E2F transcription factor 2	0.014
RUNX2	runt-related transcription factor 2	0.014
REST	RE1-silencing transcription factor	0.014
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.014
DACH1	dachshund homolog 1 (Drosophila)	0.014
BOD1L	biorientation of chromosomes in cell division 1-like	0.014
VEZF1	vascular endothelial zinc finger 1	0.014
NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	0.014
PIAS1	protein inhibitor of activated STAT, 1	0.014
PPAP2B	phosphatidic acid phosphatase type 2B	0.014
YY1	YY1 transcription factor	0.014
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.014
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	0.014
HIC1	hypermethylated in cancer 1	0.014
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.014
CCND2	cyclin D2	0.014
ZNF219	zinc finger protein 219	0.014
INTS6	integrator complex subunit 6	0.014
KIAA1712	KIAA1712	0.014
MAP2K7	mitogen-activated protein kinase kinase 7	0.014
USP42	ubiquitin specific peptidase 42	0.014
AXIN1	axin 1	0.014
WWOX	WW domain containing oxidoreductase	0.014
STC1	stanniocalcin 1	0.014
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.014
BIRC6	baculoviral IAP repeat containing 6	0.014
SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	0.014
PGR	progesterone receptor	0.014
LOXL4	lysyl oxidase-like 4	0.014
CHD1	chromodomain helicase DNA binding protein 1	0.013
DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1	0.013
C16orf87	chromosome 16 open reading frame 87	0.013
CRY2	cryptochrome 2 (photolyase-like)	0.013
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.013
MYST4	MYST histone acetyltransferase (monocytic leukemia) 4	0.013
CREB1	cAMP responsive element binding protein 1	0.013
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.013
XAB2	XPA binding protein 2	0.013
TTC19	tetratricopeptide repeat domain 19	0.013
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.013
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	0.013
GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	0.013
FUS	fused in sarcoma	0.013
GOLGA7	golgin A7	0.012
ZBTB7A	zinc finger and BTB domain containing 7A	0.012
TGFBR3	transforming growth factor, beta receptor III	0.012
TRIM28	tripartite motif containing 28	0.012
ZNF638	zinc finger protein 638	0.012
LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	0.012
ELF5	E74-like factor 5 (ets domain transcription factor)	0.012
RYBP	RING1 and YY1 binding protein	0.012
QKI	quaking homolog, KH domain RNA binding (mouse)	0.012
SAP30L	SAP30-like	0.012
EPC1	enhancer of polycomb homolog 1 (Drosophila)	0.012
RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	0.012
PRR14	proline rich 14	0.012
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.012
ZBP1	Z-DNA binding protein 1	0.012
GGPS1	geranylgeranyl diphosphate synthase 1	0.012
KAT5	K(lysine) acetyltransferase 5	0.012
BRWD1	bromodomain and WD repeat domain containing 1	0.012
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.012	Human
MAPK1	mitogen-activated protein kinase 1	0.012
C11orf30	chromosome 11 open reading frame 30	0.012
SIRT6	sirtuin 6	0.012
ING2	inhibitor of growth family, member 2	0.012
MEF2D	myocyte enhancer factor 2D	0.012
ZNF805	zinc finger protein 805	0.011
LCOR	ligand dependent nuclear receptor corepressor	0.011
NFYA	nuclear transcription factor Y, alpha	0.011
CSNK1D	casein kinase 1, delta	0.011
ZMYM4	zinc finger, MYM-type 4	0.011
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.011
RASA2	RAS p21 protein activator 2	0.011
SPRY4	sprouty homolog 4 (Drosophila)	0.011
POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	0.011
RNF40	ring finger protein 40	0.011
OSBPL3	oxysterol binding protein-like 3	0.011
CMYA5	cardiomyopathy associated 5	0.011
MIIP	migration and invasion inhibitory protein	0.011
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.011
ATF7	activating transcription factor 7	0.011
PPP1R13L	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	0.011
MATR3	matrin 3	0.011
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.011
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.011
GSTM4	glutathione S-transferase mu 4	0.011
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.011
GPS2	G protein pathway suppressor 2	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011
TAOK1	TAO kinase 1	0.011
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.011
KLF9	Kruppel-like factor 9	0.011
EHMT1	euchromatic histone-lysine N-methyltransferase 1	0.011
GAK	cyclin G associated kinase	0.011
CDK14	cyclin-dependent kinase 14	0.011
SREBF2	sterol regulatory element binding transcription factor 2	0.011
RBBP5	retinoblastoma binding protein 5	0.011
ARRB2	arrestin, beta 2	0.011
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.011
FAM53C	family with sequence similarity 53, member C	0.011
OFCC1	orofacial cleft 1 candidate 1	0.010
SRCAP	Snf2-related CREBBP activator protein	0.010
BCOR	BCL6 corepressor	0.010
ZFPM1	zinc finger protein, multitype 1	0.010
HOOK3	hook homolog 3 (Drosophila)	0.010
PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	0.010
HOXD8	homeobox D8	0.010
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.010
ZNF207	zinc finger protein 207	0.010
STX19	syntaxin 19	0.010
JAG1	jagged 1	0.010
FZD4	frizzled homolog 4 (Drosophila)	0.010
GTPBP2	GTP binding protein 2	0.010
NARS	asparaginyl-tRNA synthetase	0.010
NR2C2	nuclear receptor subfamily 2, group C, member 2	0.010
TSSC4	tumor suppressing subtransferable candidate 4	0.010
BICD1	bicaudal D homolog 1 (Drosophila)	0.010
SAP30	Sin3A-associated protein, 30kDa	0.010
ENC1	ectodermal-neural cortex 1 (with BTB-like domain)	0.010
RLF	rearranged L-myc fusion	0.010
CNOT6	CCR4-NOT transcription complex, subunit 6	0.010
CLK2	CDC-like kinase 2	0.010
C12orf35	chromosome 12 open reading frame 35	0.010