The network for 'regulation of sequence specific dna binding transcription factor activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of sequence specific dna binding transcription factor activity

Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.

Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
CREBBP CREB binding protein 1.000
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
HDAC1 histone deacetylase 1 1.000
TRAF6 TNF receptor-associated factor 6 1.000
SMAD3 SMAD family member 3 1.000
TP53 tumor protein p53 1.000
ESR1 estrogen receptor 1 1.000
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.000
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.000
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.000
TRAF2 TNF receptor-associated factor 2 1.000
EP300 E1A binding protein p300 1.000
EGFR epidermal growth factor receptor 0.999
SQSTM1 sequestosome 1 0.999
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.999
IRAK1 interleukin-1 receptor-associated kinase 1 0.999
UBC ubiquitin C 0.997
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.997
PML promyelocytic leukemia 0.997
SOCS1 suppressor of cytokine signaling 1 0.996
MYD88 myeloid differentiation primary response gene (88) 0.996
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.995
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.992
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.991
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.989
GSK3B glycogen synthase kinase 3 beta 0.989
JUN jun proto-oncogene 0.987
IRAK2 interleukin-1 receptor-associated kinase 2 0.986
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.986
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.984
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.983
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.983
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.982
BIRC2 baculoviral IAP repeat containing 2 0.981
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.980
SMAD2 SMAD family member 2 0.978
TRAF1 TNF receptor-associated factor 1 0.976
NCOR2 nuclear receptor corepressor 2 0.973
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.972
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.972
CAV1 caveolin 1, caveolae protein, 22kDa 0.972
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.971
HNF4A hepatocyte nuclear factor 4, alpha 0.970
BIRC3 baculoviral IAP repeat containing 3 0.967
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.965
IL1R1 interleukin 1 receptor, type I 0.965
ZNF43 zinc finger protein 43 0.960
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.955
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.951
MAPK14 mitogen-activated protein kinase 14 0.950
SP1 Sp1 transcription factor 0.948
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.946
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.942
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.932
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.925
SMAD1 SMAD family member 1 0.925
RIPK2 receptor-interacting serine-threonine kinase 2 0.924
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.920
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.916
DAXX death-domain associated protein 0.915
TNF tumor necrosis factor 0.915
NCOA3 nuclear receptor coactivator 3 0.909
RB1 retinoblastoma 1 0.905
PSEN1 presenilin 1 0.895
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.891
SMAD4 SMAD family member 4 0.891
POU5F1 POU class 5 homeobox 1 0.889
BCL3 B-cell CLL/lymphoma 3 0.887
BCL6 B-cell CLL/lymphoma 6 0.886
RUNX1 runt-related transcription factor 1 0.874
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.874
AR androgen receptor 0.865
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.855
APP amyloid beta (A4) precursor protein 0.852
NCOR1 nuclear receptor corepressor 1 0.851
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.851
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.837
TAL1 T-cell acute lymphocytic leukemia 1 0.836
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.830
NRP1 neuropilin 1 0.820
KAT2B K(lysine) acetyltransferase 2B 0.819
GRB2 growth factor receptor-bound protein 2 0.811
SH3KBP1 SH3-domain kinase binding protein 1 0.808
SKIL SKI-like oncogene 0.805
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.789
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.779
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.779
ANXA1 annexin A1 0.773
SMAD7 SMAD family member 7 0.772
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.771
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.766
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.761
TCEAL4 transcription elongation factor A (SII)-like 4 0.757
PIAS4 protein inhibitor of activated STAT, 4 0.756
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.751
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.748
CARD11 caspase recruitment domain family, member 11 0.744
PRKCA protein kinase C, alpha 0.735
TNIP2 TNFAIP3 interacting protein 2 0.731
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.280
ten-1 Protein TEN-1 0.139
flt-1 Protein FLT-1 0.130
pkg-1 Protein PKG-1 0.090
cst-1 Protein CST-1 0.083
nhr-67 Protein NHR-67 0.080
elt-6 Protein ELT-6 0.079
hlh-1 Protein HLH-1 0.077
pha-4 Protein PHA-4 0.076
ceh-20 Protein CEH-20 0.071
sma-6 Protein SMA-6 0.069
F53F10.2 Protein F53F10.2 0.069
hlh-2 Protein HLH-2 0.068
pry-1 Protein PRY-1 0.066
unc-40 Protein UNC-40 0.064
mab-31 Protein MAB-31 0.062
F54C9.11 Protein F54C9.11 0.060
K10D6.4 Protein K10D6.4 0.058
ttyh-1 Protein TTYH-1 0.055
daf-1 Protein DAF-1 0.054
cki-1 Protein CKI-1 0.053
cey-1 Protein CEY-1 0.053
gei-18 Protein GEI-18 0.052
sli-1 Protein SLI-1 0.050
T23F4.2 Protein T23F4.2 0.048
cnt-2 Protein CNT-2 0.048
sax-3 Protein SAX-3 0.048
C48D1.1 Protein C48D1.1 0.047
tag-298 Protein TAG-298 0.047
pas-7 Protein PAS-7 0.047
let-60 Protein LET-60 0.047
gon-2 Protein GON-2 0.046
CELE_F56D5.6 Protein F56D5.6 0.046
lin-17 Protein LIN-17 0.046
hmg-4 Protein HMG-4 0.046
nhr-69 Protein NHR-69 0.045
pad-1 Protein PAD-1 0.045
lin-25 Protein LIN-25 0.045
cst-2 Protein CST-2 0.045
let-756 Protein LET-756 0.045
lin-12 Protein LIN-12 0.044
rsa-1 Protein RSA-1 0.043
elc-1 Protein ELC-1 0.042
mrg-1 Protein MRG-1 0.042
add-2 Protein ADD-2 0.042
F35F11.1 Protein F35F11.1 0.041
cdh-3 Protein CDH-3 0.041
trim-9 Protein TRIM-9 0.041
hlh-14 Protein HLH-14 0.041
ptr-11 Protein PTR-11 0.041
Y102A11A.3 Protein Y102A11A.3 0.041
CELE_Y64G10A.7 Protein Y64G10A.7 0.040
tra-4 Protein TRA-4 0.040
daf-3 Protein DAF-3 0.040
H06I04.1 Protein H06I04.1 0.040
pes-1 Protein PES-1 0.039
T07H6.1 Protein T07H6.1 0.039
tps-1 Protein TPS-1 0.039
brp-1 Protein BRP-1 0.039
nhr-25 Protein NHR-25 0.039
zer-1 Protein ZER-1 0.039
lit-1 Protein LIT-1 0.038
lin-11 Protein LIN-11 0.038
ceh-16 Protein CEH-16 0.038
R05G6.10 Protein R05G6.10 0.038
F59C12.3 Protein F59C12.3 0.038
ceh-27 Protein CEH-27 0.038
inx-19 Protein INX-19 0.038
fkh-2 Protein FKH-2 0.038
F10G2.4 Protein F10G2.4 0.037
gap-2 Protein GAP-2 0.037
zoo-1 Protein ZOO-1 0.037
mec-15 Protein MEC-15 0.037
pbs-2 Protein PBS-2 0.037
fmi-1 Protein FMI-1 0.037
C27A12.7 Protein C27A12.7 0.037
ctg-1 Protein CTG-1 0.037
gpb-2 Protein GPB-2 0.037
ain-1 Protein AIN-1 0.037
pbs-5 Protein PBS-5 0.036
nhr-34 Protein NHR-34 0.036
C25E10.12 Protein C25E10.12 0.036
magi-1 Protein MAGI-1 0.036
bli-1 Protein BLI-1 0.036
F46G10.1 Protein F46G10.1 0.036
mel-11 Protein MEL-11 0.036
mnp-1 Protein MNP-1 0.036
C34F6.10 Protein C34F6.10 0.036
ceh-44 Protein CEH-44 0.036
T08A11.1 Protein T08A11.1 0.035
ceh-6 Protein CEH-6 0.035
C28H8.3 Protein C28H8.3 0.035
maea-1 Protein MAEA-1 0.035
H01M10.1 Protein H01M10.1 0.035
csnk-1 Protein CSNK-1 0.035
sdz-28 Protein SDZ-28 0.034
T19D12.6 Protein T19D12.6 0.034
H10E21.1 Protein H10E21.1 0.034
tag-253 Protein TAG-253 0.034
sek-1 Protein SEK-1 0.034
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Danio rerio
Name Description Probability Func Analog Organism
shha sonic hedgehog a 0.972
sox3 SRY-box containing gene 3 0.692
gata6 GATA-binding protein 6 0.690
sox9b SRY-box containing gene 9b 0.618
chd chordin 0.311
tp53 tumor protein p53 0.279
wnt4a wingless-type MMTV integration site family, member 4a 0.217
foxa2 forkhead box A2 0.202
LOC557072 caspase recruitment domain-containing protein 11-like 0.188
arl4ab ADP-ribosylation factor-like 4ab 0.183
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 0.177
fsta follistatin a 0.169
sox2 SRY-box containing gene 2 0.169
tbx1 T-box 1 0.168
ptch2 patched 2 0.145
fgf8a fibroblast growth factor 8 a 0.143
dlx3b distal-less homeobox gene 3b 0.136
neo1 neogenin 1 0.134
tlr3 toll-like receptor 3 0.128
rarga retinoic acid receptor gamma a 0.123
foxa3 forkhead box A3 0.110
sox9a SRY-box containing gene 9a 0.108
vasa vasa homolog 0.099
tfap2a transcription factor AP-2 alpha 0.097
ca2 carbonic anhydrase II 0.092
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.090
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.089
lft1 lefty1 0.088
fn1 fibronectin 1 0.085
stc1l stanniocalcin 1, like 0.084
spi1l spleen focus forming virus (SFFV) proviral integration oncogene spi1 like 0.080
fancl Fanconi anemia, complementation group L 0.073
nkx2.2a NK2 transcription factor related 2a 0.073
csf3r colony stimulating factor 3 receptor (granulocyte) 0.072
runx1 runt-related transcription factor 1 0.071
kdrl kinase insert domain receptor like 0.066
si:ch211-235f6.2 si:ch211-235f6.2 0.060
lmo2 LIM domain only 2 (rhombotin-like 1) 0.059
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.059
sox11a SRY-box containing gene 11a 0.059
alcama activated leukocyte cell adhesion molecule a 0.058
gata4 GATA-binding protein 4 0.058
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.056
mib mind bomb 0.055
gata5 GATA-binding protein 5 0.055
kiss1rb KISS1 receptor b 0.055
nod1 nucleotide-binding oligomerization domain containing 1 0.053
fabp2 fatty acid binding protein 2, intestinal 0.053
rgs4 regulator of G-protein signalling 4 0.052
hhex hematopoietically expressed homeobox 0.052
wnt3 wingless-type MMTV integration site family, member 3 0.049
flh floating head 0.043
ar androgen receptor 0.042
cpox coproporphyrinogen oxidase 0.042
sox7 SRY-box containing gene 7 0.040
etv2 ets variant gene 2 0.040
lgi1b leucine-rich, glioma inactivated 1b 0.040
fzd5 frizzled homolog 5 0.039
rag1 recombination activating gene 1 0.039
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.038
btk Bruton agammaglobulinemia tyrosine kinase 0.036
hnf1ba HNF1 homeobox Ba 0.036
defbl1 defensin, beta-like 1 0.036
LOC100151531 zinc finger protein Gfi-1b-like 0.035
twist1b twist1b 0.035
wnt1 wingless-type MMTV integration site family, member 1 0.035
sod2 superoxide dismutase 2, mitochondrial 0.033
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.033
igf2a insulin-like growth factor 2a 0.032
igf1ra insulin-like growth factor 1a receptor 0.032
sfrp1a secreted frizzled-related protein 1a 0.032
ins preproinsulin 0.031
dlc deltaC 0.031
elk4 ELK4, ETS-domain protein 0.031
grifin galectin related inter-fiber protein 0.030
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.030
meis1 myeloid ecotropic viral integration 1 0.029
itm2bb integral membrane protein 2Bb 0.028
boc brother of CDO 0.028
csnk1da casein kinase 1, delta a 0.028
axin2 axin 2 (conductin, axil) 0.028
wif1 wnt inhibitory factor 1 0.028
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.028
mbnl2 muscleblind-like 2 (Drosophila) 0.028
ip6k2 inositol hexaphosphate kinase 2 0.027
ntrk3b neurotrophic tyrosine kinase, receptor, type 3b 0.027
ripk2 receptor-interacting serine-threonine kinase 2 0.027
sox4b SRY-box containing gene 4b 0.027
tbpl2 TATA box binding protein like 2 0.027
mdkb midkine-related growth factor b 0.026
thrab thyroid hormone receptor alpha b 0.026
tlr18 toll-like receptor 18 0.026
gli1 GLI-Kruppel family member 1 0.026
fev FEV (ETS oncogene family) 0.026
figla factor in the germline alpha 0.025
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.025
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.025
pitx2 paired-like homeodomain transcription factor 2 0.025
drl draculin 0.025
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.024
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Drosophila melanogaster
Name Description Probability Func Analog Organism
shn schnurri 0.764
ci cubitus interruptus 0.724
G-salpha60A G protein salpha 60A 0.375
Mad Mothers against dpp 0.318
phl pole hole 0.202
Rac1 CG2248 gene product from transcript CG2248-RA 0.194
hth homothorax 0.174
Pvr PDGF- and VEGF-receptor related 0.158
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.138
tkv thickveins 0.137
ex expanded 0.123
InR Insulin-like receptor 0.107
bsk basket 0.101
hh hedgehog 0.092
Rho1 CG8416 gene product from transcript CG8416-RB 0.088
ap apterous 0.084
brat brain tumor 0.075
Egfr Epidermal growth factor receptor 0.068
Pi3K68D Phosphotidylinositol 3 kinase 68D 0.065
hep hemipterous 0.065
yki yorkie 0.064
fz frizzled 0.058
trx trithorax 0.058
Rel Relish 0.057
pan pangolin 0.053
ttv tout-velu 0.048
en engrailed 0.047
dom domino 0.045
dpp decapentaplegic 0.044
ash2 absent, small, or homeotic discs 2 0.043
Hsf Heat shock factor 0.040
tsh teashirt 0.039
Akt1 CG4006 gene product from transcript CG4006-RA 0.037
18w 18 wheeler 0.036
Mes2 CG11100 gene product from transcript CG11100-RB 0.034
SF2 CG6987 gene product from transcript CG6987-RA 0.032
cos costa 0.032
cals calsyntenin-1 0.032
Stat92E Signal-transducer and activator of transcription protein at 92E 0.030
wg wingless 0.026
HLH54F CG5005 gene product from transcript CG5005-RA 0.025
spi spitz 0.024
Duox Dual oxidase 0.023
Toll-7 CG8595 gene product from transcript CG8595-RA 0.022
Mer Merlin 0.022
tup tailup 0.022
ewg erect wing 0.021
Sir2 CG5216 gene product from transcript CG5216-RA 0.020
Pka-C1 cAMP-dependent protein kinase 1 0.020
Tl Toll 0.018
tamo CG4057 gene product from transcript CG4057-RA 0.018
grn grain 0.018
fng fringe 0.018
Mekk1 CG7717 gene product from transcript CG7717-RB 0.018
Sxl Sex lethal 0.017
Cat Catalase 0.017
ctp cut up 0.017
bowl brother of odd with entrails limited 0.016
Nrx-IV Neurexin IV 0.016
stai stathmin 0.016
fu fused 0.016
CG3573 CG3573 gene product from transcript CG3573-RA 0.015
dco discs overgrown 0.015
Gug Grunge 0.015
gro groucho 0.015
ds dachsous 0.015
slo slowpoke 0.015
eya eyes absent 0.015
ovo CG6824 gene product from transcript CG6824-RE 0.015
tin tinman 0.014
rap retina aberrant in pattern 0.014
Atg1 Autophagy-specific gene 1 0.014
wts warts 0.014
CG14219 CG14219 gene product from transcript CG14219-RA 0.014
lwr lesswright 0.014
sima similar 0.014
dsh dishevelled 0.014
beat-Ia beaten path Ia 0.013
CG31224 CG31224 gene product from transcript CG31224-RA 0.013
egr eiger 0.013
pnr pannier 0.013
gbb glass bottom boat 0.013
hpo hippo 0.013
sns sticks and stones 0.013
so sine oculis 0.013
Rdl Resistant to dieldrin 0.013
vri vrille 0.012
eIF-4E Eukaryotic initiation factor 4E 0.012
dally division abnormally delayed 0.012
Pros35 Proteasome 35kD subunit 0.012
Src64B Src oncogene at 64B 0.012
cyc cycle 0.012
os outstretched 0.011
disco disconnected 0.011
chico CG5686 gene product from transcript CG5686-RB 0.011
Pcaf CG4107 gene product from transcript CG4107-RA 0.011
Chro Chromator 0.010
CadN Cadherin-N 0.010
sbb scribbler 0.010
zfh2 Zn finger homeodomain 2 0.010
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Tnf tumor necrosis factor 1.000
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 1.000
Traf6 TNF receptor-associated factor 6 1.000
Gli2 GLI-Kruppel family member GLI2 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.998
Gli3 GLI-Kruppel family member GLI3 0.998
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.997
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.996
Fgfr1 fibroblast growth factor receptor 1 0.991
Shh sonic hedgehog 0.991
Rarg retinoic acid receptor, gamma 0.988
Eya1 eyes absent 1 homolog (Drosophila) 0.987
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.987
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.984
Trp53 transformation related protein 53 0.984
Pax8 paired box gene 8 0.979
Foxc2 forkhead box C2 0.978
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.978
Bmp4 bone morphogenetic protein 4 0.977
Fgfr2 fibroblast growth factor receptor 2 0.973
Foxa2 forkhead box A2 0.972
Dab1 disabled homolog 1 (Drosophila) 0.970
Ncoa3 nuclear receptor coactivator 3 0.963
Lhx1 LIM homeobox protein 1 0.959
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.958
Foxc1 forkhead box C1 0.957
Pax6 paired box gene 6 0.957
Pax2 paired box gene 2 0.952
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.951
Igh immunoglobulin heavy chain complex 0.943
Tcf3 transcription factor 3 0.942
Tgfb2 transforming growth factor, beta 2 0.937
Otx2 orthodenticle homolog 2 (Drosophila) 0.933
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.933
Zeb1 zinc finger E-box binding homeobox 1 0.931
Smad6 MAD homolog 6 (Drosophila) 0.928
Socs1 suppressor of cytokine signaling 1 0.917
Gata4 GATA binding protein 4 0.915
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.912
Fas Fas (TNF receptor superfamily member 6) 0.907
Lyz2 lysozyme 2 0.904
Neurod1 neurogenic differentiation 1 0.901
Lepr leptin receptor 0.896
Pparg peroxisome proliferator activated receptor gamma 0.884
Ptgs2 prostaglandin-endoperoxide synthase 2 0.880
Runx1 runt related transcription factor 1 0.869
Pitx2 paired-like homeodomain transcription factor 2 0.869
Cd40 CD40 antigen 0.866
Cd44 CD44 antigen 0.862
Vegfa vascular endothelial growth factor A 0.860
Tlr4 toll-like receptor 4 0.856
Twist2 twist homolog 2 (Drosophila) 0.852
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.851
Rb1 retinoblastoma 1 0.850
Stat3 signal transducer and activator of transcription 3 0.842
Hif1a hypoxia inducible factor 1, alpha subunit 0.840
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.835
Insr insulin receptor 0.834
Adam17 a disintegrin and metallopeptidase domain 17 0.830
Ldb3 LIM domain binding 3 0.828
Kiss1 KiSS-1 metastasis-suppressor 0.810
Ikzf1 IKAROS family zinc finger 1 0.790
Apc adenomatosis polyposis coli 0.772
Neurog2 neurogenin 2 0.768
Ptf1a pancreas specific transcription factor, 1a 0.766
Notch1 Notch gene homolog 1 (Drosophila) 0.760
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.760
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.745
Fgf10 fibroblast growth factor 10 0.744
Amhr2 anti-Mullerian hormone type 2 receptor 0.741
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.735
Myd88 myeloid differentiation primary response gene 88 0.729
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.727
Sox2 SRY-box containing gene 2 0.725
Vangl2 vang-like 2 (van gogh, Drosophila) 0.719
Hand1 heart and neural crest derivatives expressed transcript 1 0.714
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.711
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.705
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.698
Dlx5 distal-less homeobox 5 0.695
Nkx2-1 NK2 homeobox 1 0.694
Rara retinoic acid receptor, alpha 0.693
Ar androgen receptor 0.685
Arrb1 arrestin, beta 1 0.681
Egr2 early growth response 2 0.675
Itch itchy, E3 ubiquitin protein ligase 0.672
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.672
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.670
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.666
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.662
Axin1 axin 1 0.660
Csf1 colony stimulating factor 1 (macrophage) 0.658
Sox9 SRY-box containing gene 9 0.651
Kdm2b lysine (K)-specific demethylase 2B 0.648
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.648
Hdac7 histone deacetylase 7 0.646
Hdac2 histone deacetylase 2 0.641
Insm1 insulinoma-associated 1 0.622
Prrx2 paired related homeobox 2 0.620
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.105
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.049
Klf6 Kruppel-like factor 6 0.049
Lhb luteinizing hormone beta 0.046
Id1 inhibitor of DNA binding 1 0.046
Usf2 upstream transcription factor 2, c-fos interacting 0.042
Robo1 roundabout homolog 1 (Drosophila) 0.038
Tgfbr2 transforming growth factor, beta receptor II 0.035
Icam1 intercellular adhesion molecule 1 0.035
Uhmk1 U2AF homology motif (UHM) kinase 1 0.034
Jak1 Janus kinase 1 0.031
Anxa2 annexin A2 0.030
Cxcl10 chemokine (C-X-C motif) ligand 10 0.027
Pacs1 phosphofurin acidic cluster sorting protein 1 0.027
Myd88 myeloid differentiation primary response gene 88 0.025
Dusp1 dual specificity phosphatase 1 0.024
Id3 inhibitor of DNA binding 3 0.024
Cnga4 cyclic nucleotide gated channel alpha 4 0.023
LOC100362331 rCG59612-like 0.023
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.023
Ivl involucrin 0.022
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.022
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.022
Gfra2 GDNF family receptor alpha 2 0.022
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.022
Ubtf upstream binding transcription factor, RNA polymerase I 0.022
Galr2 galanin receptor 2 0.021
Bcl2 B-cell CLL/lymphoma 2 0.021
Gna15 guanine nucleotide binding protein, alpha 15 0.021
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.021
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.021
Gabbr2 gamma-aminobutyric acid (GABA) B receptor 2 0.021
Zyx zyxin 0.021
Tcf3 transcription factor 3 0.021
Ccnd3 cyclin D3 0.021
Alox5 arachidonate 5-lipoxygenase 0.020
Sbk1 SH3-binding domain kinase 1 0.020
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.020
Prlh prolactin releasing hormone 0.020
Fgfr2 fibroblast growth factor receptor 2 0.020
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.020
Nfic nuclear factor I/C 0.020
Il1a interleukin 1 alpha 0.020
Dll3 delta-like 3 (Drosophila) 0.020
Hrh2 histamine receptor H 2 0.019
Hoxa1 homeo box A1 0.019
Myo1b myosin Ib 0.019
Cd247 Cd247 molecule 0.019
Col9a1 collagen, type IX, alpha 1 0.019
Cntfr ciliary neurotrophic factor receptor 0.019
Cast calpastatin 0.019
Ptms parathymosin 0.019
Sgk1 serum/glucocorticoid regulated kinase 1 0.019
Ptprc protein tyrosine phosphatase, receptor type, C 0.018
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.018
Has2 hyaluronan synthase 2 0.018
Foxd4 forkhead box D4 0.018
Mthfr methylenetetrahydrofolate reductase (NAD(P)H) 0.017
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.017
Hmox1 heme oxygenase (decycling) 1 0.017
Csf1 colony stimulating factor 1 (macrophage) 0.017
Bex4 brain expressed, X-linked 4 0.017
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.017
Ptafr platelet-activating factor receptor 0.017
Smad7 SMAD family member 7 0.017
Mmp12 matrix metallopeptidase 12 0.017
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.017
Gpr176 G protein-coupled receptor 176 0.017
Scnn1b sodium channel, nonvoltage-gated 1, beta 0.017
Sdc3 syndecan 3 0.017
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.017
Klk1b21 kallikrein 1-related peptidase b21 0.017
Rgs12 regulator of G-protein signaling 12 0.017
Orai1 ORAI calcium release-activated calcium modulator 1 0.016
P2ry2 purinergic receptor P2Y, G-protein coupled, 2 0.016
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.016
C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 0.016
Trim47 tripartite motif-containing 47 0.016
Igfbp5 insulin-like growth factor binding protein 5 0.016
Jak2 Janus kinase 2 0.016
Zfp36 zinc finger protein 36 0.016
Hoxc4 homeo box C4 0.016
Dock8 dedicator of cytokinesis 8 0.016
Nfasc neurofascin 0.016
Irf1 interferon regulatory factor 1 0.016
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.016
LOC100360501 ribonuclease inhibitor-like 0.016
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.016
Psgb1 pregnancy-specific beta 1-glycoprotein 0.016
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.016
Csnk1g2 casein kinase 1, gamma 2 0.016
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.015
Myh9 myosin, heavy chain 9, non-muscle 0.015
Klf12 Kruppel-like factor 12 0.015
Socs3 suppressor of cytokine signaling 3 0.015
Nr2f6 nuclear receptor subfamily 2, group F, member 6 0.015
Pde4d phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) 0.015
Bmpr1a bone morphogenetic protein receptor, type IA 0.015
Scamp2 secretory carrier membrane protein 2 0.015
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.015
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
TPK1 Tpk1p 0.206
RPT3 Rpt3p 0.163
RAS2 Ras2p 0.124
CKA2 Cka2p 0.108
FUS3 Fus3p 0.067
RPT4 Rpt4p 0.054
PHB2 Phb2p 0.052
ASK10 Ask10p 0.046
RPN14 Rpn14p 0.039
ATG13 Atg13p 0.037
PKC1 Pkc1p 0.036
PUP3 Pup3p 0.035
KSS1 Kss1p 0.030
EDE1 Ede1p 0.030
PTK2 Ptk2p 0.029
SPT15 Spt15p 0.029
TEC1 Tec1p 0.029
FAB1 Fab1p 0.028
MSG5 Msg5p 0.026
MOT1 Mot1p 0.026
HDA2 Hda2p 0.023
TOA1 Toa1p 0.023
GAL4 Gal4p 0.022
YPL260W hypothetical protein 0.021
RRT5 Rrt5p 0.021
ULP2 Ulp2p 0.020
KAP114 Kap114p 0.020
DIG1 Dig1p 0.019
RSC9 Rsc9p 0.017
RTF1 Rtf1p 0.017
LAP4 Lap4p 0.017
TAF8 Taf8p 0.016
YNL134C hypothetical protein 0.016
PRE10 Pre10p 0.016
CMK1 Cmk1p 0.016
SGF73 Sgf73p 0.015
KIN1 Kin1p 0.014
PSK1 Psk1p 0.014
AHP1 Ahp1p 0.014
KDX1 Kdx1p 0.014
AOS1 Aos1p 0.014
HRR25 Hrr25p 0.014
BCY1 Bcy1p 0.013
CKA1 Cka1p 0.012
YCK1 Yck1p 0.012
ROD1 Rod1p 0.012
PCL9 Pcl9p 0.012
RCK1 Rck1p 0.012
YPL088W hypothetical protein 0.012
YLR264C-A hypothetical protein 0.011
GYL1 Gyl1p 0.011
SRD1 Srd1p 0.011
URA3 Ura3p 0.011
YHI9 Yhi9p 0.011
ECM29 Ecm29p 0.011
TAF6 Taf6p 0.011
YLR419W hypothetical protein 0.011
RPN9 Rpn9p 0.011
RPN2 Rpn2p 0.010
STE7 Ste7p 0.010
LEU2 Leu2p 0.010
CMK2 Cmk2p 0.010
PEX5 Pex5p 0.010
HAL5 Hal5p 0.010