The network for 'somatic cell dna recombination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

somatic cell dna recombination

Recombination occurring within or between DNA molecules in somatic cells.

Mus musculus
Name Description Probability Func Analog Organism
Ikzf1 IKAROS family zinc finger 1 0.998
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.992
Cd28 CD28 antigen 0.986
Tnf tumor necrosis factor 0.984
Rag2 recombination activating gene 2 0.981
Ifng interferon gamma 0.955
Il10 interleukin 10 0.946
Cd19 CD19 antigen 0.933
Socs1 suppressor of cytokine signaling 1 0.928
Igh immunoglobulin heavy chain complex 0.926
Pten phosphatase and tensin homolog 0.903
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.895
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.886
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.879
Fyn Fyn proto-oncogene 0.875
Stat5b signal transducer and activator of transcription 5B 0.850
Lta lymphotoxin A 0.792
Prf1 perforin 1 (pore forming protein) 0.791
Atm ataxia telangiectasia mutated homolog (human) 0.743
Cd40 CD40 antigen 0.729
Pdcd1 programmed cell death 1 0.683
Pitx1 paired-like homeodomain transcription factor 1 0.674
Foxp3 forkhead box P3 0.610
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.586
Tcf3 transcription factor 3 0.581
Il4 interleukin 4 0.579
Il2 interleukin 2 0.533
Stat5a signal transducer and activator of transcription 5A 0.521
Tbx21 T-box 21 0.501
Ltb lymphotoxin B 0.497
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.496
Fasl Fas ligand (TNF superfamily, member 6) 0.473
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.471
Il4ra interleukin 4 receptor, alpha 0.471
Tbx3 T-box 3 0.467
Pou5f1 POU domain, class 5, transcription factor 1 0.464
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.448
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.440
Rag1 recombination activating gene 1 0.429
Irf9 interferon regulatory factor 9 0.428
Zeb1 zinc finger E-box binding homeobox 1 0.366
Hspa9 heat shock protein 9 0.346
Tcra T-cell receptor alpha chain 0.341
Rc3h1 RING CCCH (C3H) domains 1 0.327
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.306
Bcl6 B-cell leukemia/lymphoma 6 0.296
Lck lymphocyte protein tyrosine kinase 0.281
Lat linker for activation of T cells 0.281
Pitx2 paired-like homeodomain transcription factor 2 0.281
Brca1 breast cancer 1 0.281
Fas Fas (TNF receptor superfamily member 6) 0.263
Il6 interleukin 6 0.252
Inpp5d inositol polyphosphate-5-phosphatase D 0.242
Tal1 T-cell acute lymphocytic leukemia 1 0.231
Dll4 delta-like 4 (Drosophila) 0.223
Sh2d1a SH2 domain protein 1A 0.215
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.210
Id2 inhibitor of DNA binding 2 0.179
Irf4 interferon regulatory factor 4 0.172
Cdx2 caudal type homeobox 2 0.170
Stat6 signal transducer and activator of transcription 6 0.169
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.169
Icos inducible T-cell co-stimulator 0.168
Il2rg interleukin 2 receptor, gamma chain 0.162
Il6st interleukin 6 signal transducer 0.156
Lig4 ligase IV, DNA, ATP-dependent 0.149
Il12rb1 interleukin 12 receptor, beta 1 0.148
Runx1 runt related transcription factor 1 0.143
Trp53 transformation related protein 53 0.142
Trim21 tripartite motif-containing 21 0.139
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.134
Cd247 CD247 antigen 0.133
Hoxa1 homeobox A1 0.132
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.130
Cd274 CD274 antigen 0.129
Cd4 CD4 antigen 0.126
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.117
Fgf10 fibroblast growth factor 10 0.117
Cyld cylindromatosis (turban tumor syndrome) 0.112
Gja5 gap junction protein, alpha 5 0.111
Sh2d2a SH2 domain protein 2A 0.111
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.111
Nbn nibrin 0.109
Lyst lysosomal trafficking regulator 0.104
Tcf4 transcription factor 4 0.103
Tbx4 T-box 4 0.103
Stat3 signal transducer and activator of transcription 3 0.100
Rad50 RAD50 homolog (S. cerevisiae) 0.100
Cd160 CD160 antigen 0.098
Dclre1c DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) 0.096
Orc1 origin recognition complex, subunit 1 0.096
Tbx5 T-box 5 0.096
Il21r interleukin 21 receptor 0.094
Traf1 TNF receptor-associated factor 1 0.094
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.093
Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.091
Traf2 TNF receptor-associated factor 2 0.091
Gdf3 growth differentiation factor 3 0.091
Runx3 runt related transcription factor 3 0.089
Sall4 sal-like 4 (Drosophila) 0.089
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.295
chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.129
msh6 mutS homolog 6 (E. coli) 0.122
hmgb1a high-mobility group box 1a 0.122
mybl2 myeloblastosis oncogene-like 2 0.119
pola1 polymerase (DNA directed), alpha 1 0.100
frem1a Fras1 related extracellular matrix 1a 0.084
msh2 mutS homolog 2 (E. coli) 0.070
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.061
axin1 axin 1 0.054
hirip3 HIRA interacting protein 3 0.053
pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) 0.052
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.049
zgc:174506 zgc:174506 0.047
setdb1a SET domain, bifurcated 1a 0.046
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.045
atad5a ATPase family, AAA domain containing 5a 0.044
zgc:56197 zgc:56197 0.044
sec31a sec31 homolog A (S. cerevisiae) 0.043
brip1 BRCA1 interacting protein C-terminal helicase 1 0.043
npat nuclear protein, ataxia-telangiectasia locus 0.041
rad54l RAD54-like (S. cerevisiae) 0.041
tgfb2 transforming growth factor, beta 2 0.041
dlx4a distal-less homeobox gene 4a 0.040
ext1b exostoses (multiple) 1b 0.040
chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) 0.039
ankrd6 ankyrin repeat domain 6 0.038
si:ch211-1n9.7 si:ch211-1n9.7 0.038
coro1a coronin, actin binding protein, 1A 0.037
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.036
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.036
cdc7 cell division cycle 7 homolog (S. cerevisiae) 0.035
prmt1 protein arginine methyltransferase 1 0.035
dclre1a DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) 0.035
rag2 recombination activating gene 2 0.034
zfp36l1a zinc finger protein 36, C3H type-like 1a 0.033
rag1 recombination activating gene 1 0.033
mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.031
tert telomerase reverse transcriptase 0.031
dnmt7 DNA (cytosine-5-)-methyltransferase 7 0.030
rad18 RAD18 homolog (S. cerevisiae) 0.030
pola2 polymerase (DNA directed), alpha 2 0.030
lrrc33 leucine rich repeat containing 33 0.029
zgc:86870 zgc:86870 0.028
brca2 breast cancer 2, early onset 0.028
zgc:154089 zgc:154089 0.027
insrb insulin receptor b 0.027
ehmt2 euchromatic histone-lysine N-methyltransferase 2 0.027
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.026
fhla four and a half LIM domains a 0.026
zgc:56039 zgc:56039 0.025
zgc:92014 zgc:92014 0.025
zgc:86841 zgc:86841 0.025
mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) 0.024
LOC567504 interferon-induced protein with tetratricopeptide repeats 5-like 0.023
efna2 ephrin A2 0.023
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.023
tbx22 T-box 22 0.023
hs3st3b1b heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b 0.022
fgf20a fibroblast growth factor 20a 0.022
mcm7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.022
tufm Tu translation elongation factor, mitochondrial 0.022
zgc:123282 zgc:123282 0.022
ttk ttk protein kinase 0.022
zgc:113143 zgc:113143 0.022
phf16 PHD finger protein 16 0.022
anapc5 anaphase promoting complex subunit 5 0.022
zgc:100817 zgc:100817 0.022
mical3 flavoprotein oxidoreductase MICAL3 0.021
cmyb transcription factor cmyb 0.021
dntt deoxynucleotidyltransferase, terminal 0.021
skiv2l2 superkiller viralicidic activity 2-like 2 0.021
pms1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.021
apc adenomatosis polyposis coli 0.021
kif15 kinesin family member 15 0.021
ahr2 aryl hydrocarbon receptor 2 0.020
dtl denticleless homolog (Drosophila) 0.020
aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.020
si:ch211-198a12.6 si:ch211-198a12.6 0.020
zgc:112254 zgc:112254 0.020
tagln transgelin 0.020
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.020
ddx20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.020
brd2b bromodomain containing 2b 0.020
wu:fc18c07 wu:fc18c07 0.020
zgc:77551 zgc:77551 0.020
rif1 RAP1 interacting factor homolog (yeast) 0.019
pole2 polymerase (DNA directed), epsilon 2 0.019
mmp17a matrix metallopeptidase 17a 0.019
abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.019
smc4 structural maintenance of chromosomes 4 0.019
cltca clathrin, heavy polypeptide a (Hc) 0.019
bmpr1bb bone morphogenetic protein receptor, type 1bb 0.019
grn1 granulin 1 0.019
tbx21 T-box 21 0.019
rpa1 replication protein A1 0.019
otpa orthopedia homolog a 0.018
lin54 lin-54 homolog 0.018
chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.018
brd8 bromodomain containing 8 0.018
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Drosophila melanogaster
Name Description Probability Func Analog Organism
mus101 mutagen-sensitive 101 0.019
debcl death executioner Bcl-2 homologue 0.015
nbs CG6754 gene product from transcript CG6754-RC 0.014
rad50 CG6339 gene product from transcript CG6339-RD 0.014
mus205 mutagen-sensitive 205 0.011
Rbf Retinoblastoma-family protein 0.011
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Homo sapiens
Name Description Probability Func Analog Organism
BRCA1 breast cancer 1, early onset 0.306
IL4R interleukin 4 receptor 0.258
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.211
MDC1 mediator of DNA-damage checkpoint 1 0.098
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.084
H2AFX H2A histone family, member X 0.079
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.053
APLF aprataxin and PNKP like factor 0.045
RAD50 RAD50 homolog (S. cerevisiae) 0.035
MSH6 mutS homolog 6 (E. coli) 0.034
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.025
THOC4 THO complex 4 0.023
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.021
TP53BP1 tumor protein p53 binding protein 1 0.016
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.015
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.015
MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.014
GRAP2 GRB2-related adaptor protein 2 0.013
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.012
FANCD2 Fanconi anemia, complementation group D2 0.012
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.012
MSH3 mutS homolog 3 (E. coli) 0.012
PARP1 poly (ADP-ribose) polymerase 1 0.011
TAL1 T-cell acute lymphocytic leukemia 1 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hsph1 heat shock 105/110 protein 1 0.217
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.150
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.125
Hck hemopoietic cell kinase 0.047
Hspa8 heat shock protein 8 0.036
Arl5c ADP-ribosylation factor-like 5C 0.034
Casp1 caspase 1 0.031
Ppid peptidylprolyl isomerase D (cyclophilin D) 0.029
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.027
Cxcr4 chemokine (C-X-C motif) receptor 4 0.027
Bin2 bridging integrator 2 0.026
Ctse cathepsin E 0.024
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.021
Plcg2 phospholipase C, gamma 2 0.020
Nudc nuclear distribution gene C homolog (A. nidulans) 0.019
LOC681996 similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 1 0.018
RGD1305222 similar to RIKEN cDNA 1810029B16 0.017
Cd37 CD37 molecule 0.017
Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.017
St13 suppression of tumorigenicity 13 0.016
Zyx zyxin 0.016
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.016
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.015
Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.015
Trpv2 transient receptor potential cation channel, subfamily V, member 2 0.015
Tgfbr2 transforming growth factor, beta receptor II 0.015
Vcan versican 0.015
Serbp1 Serpine1 mRNA binding protein 1 0.015
Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.015
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.014
Hspa5 heat shock protein 5 0.014
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.013
Il1b interleukin 1 beta 0.013
Igh-6 immunoglobulin heavy chain 6 0.013
Fh1 fumarate hydratase 1 0.013
Lhx5 LIM homeobox 5 0.013
Ldb1 LIM domain binding 1 0.013
Laptm5 lysosomal protein transmembrane 5 0.013
Cd2 Cd2 molecule 0.013
Sec31a SEC31 homolog A (S. cerevisiae) 0.013
Hspe1 heat shock protein 1 (chaperonin 10) 0.012
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.012
Syk spleen tyrosine kinase 0.012
Anpep alanyl (membrane) aminopeptidase 0.012
Psgb1 pregnancy-specific beta 1-glycoprotein 0.012
Ier5l immediate early response 5-like 0.012
Cd4 Cd4 molecule 0.012
Sirpa signal-regulatory protein alpha 0.012
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.012
Sh2b2 SH2B adaptor protein 2 0.012
Bche butyrylcholinesterase 0.012
Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.012
Itga6 integrin, alpha 6 0.012
Psd4 pleckstrin and Sec7 domain containing 4 0.012
Rxra retinoid X receptor alpha 0.011
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.011
Ripk3 receptor-interacting serine-threonine kinase 3 0.011
Vcam1 vascular cell adhesion molecule 1 0.011
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.011
Mca32 mast cell antigen 32 0.011
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.011
Dact2 dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) 0.011
Il2rg interleukin 2 receptor, gamma 0.011
Prss2 protease, serine, 2 0.011
Clec9a C-type lectin domain family 9, member a 0.011
Klf2 Kruppel-like factor 2 (lung) 0.011
Plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.011
Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 0.011
Pgk1 phosphoglycerate kinase 1 0.011
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.011
Il16 interleukin 16 0.011
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.011
Fgfr1 Fibroblast growth factor receptor 1 0.011
Cd44 Cd44 molecule 0.011
Arhgap25 Rho GTPase activating protein 25 0.011
Usf2 upstream transcription factor 2, c-fos interacting 0.011
Pcgf6 polycomb group ring finger 6 0.011
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.011
Dnm2 dynamin 2 0.011
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.011
ND4 NADH dehydrogenase subunit 4 0.011
Scn9a sodium channel, voltage-gated, type IX, alpha 0.011
Il4ra interleukin 4 receptor, alpha 0.011
Fgb fibrinogen beta chain 0.011
Smad7 SMAD family member 7 0.010
LOC100360406 rCG34104-like 0.010
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.010
P22k15 cystatin related protein 2 0.010
Mapk7 mitogen-activated protein kinase 7 0.010
Il2rb interleukin 2 receptor, beta 0.010
RGD1311723 similar to KIAA1731 protein 0.010
Il6 interleukin 6 0.010
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.010
Accn5 amiloride-sensitive cation channel 5, intestinal 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism