The network for 'regulation of t cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of t cell proliferation

Any process that modulates the frequency, rate or extent of T cell proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Cd40 CD40 antigen 0.998
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.992
Efnb2 ephrin B2 0.983
Lyz2 lysozyme 2 0.974
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.953
Fgfr2 fibroblast growth factor receptor 2 0.953
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.938
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.932
Batf basic leucine zipper transcription factor, ATF-like 0.924
Rnf2 ring finger protein 2 0.896
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.896
Ccr1 chemokine (C-C motif) receptor 1 0.892
Stat3 signal transducer and activator of transcription 3 0.889
Tnf tumor necrosis factor 0.889
Ccr7 chemokine (C-C motif) receptor 7 0.865
Tgfb2 transforming growth factor, beta 2 0.864
Cd28 CD28 antigen 0.859
Btk Bruton agammaglobulinemia tyrosine kinase 0.842
Fas Fas (TNF receptor superfamily member 6) 0.840
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.820
Il1b interleukin 1 beta 0.817
Ifng interferon gamma 0.811
Adam17 a disintegrin and metallopeptidase domain 17 0.808
Foxp3 forkhead box P3 0.795
Icos inducible T-cell co-stimulator 0.794
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.790
Il4 interleukin 4 0.782
Rybp RING1 and YY1 binding protein 0.782
Casp8 caspase 8 0.780
Grb2 growth factor receptor bound protein 2 0.770
Lta lymphotoxin A 0.757
Ciita class II transactivator 0.741
Zeb1 zinc finger E-box binding homeobox 1 0.741
Ccl2 chemokine (C-C motif) ligand 2 0.740
Stat5b signal transducer and activator of transcription 5B 0.734
Nlrp3 NLR family, pyrin domain containing 3 0.717
Egfr epidermal growth factor receptor 0.716
Cd3e CD3 antigen, epsilon polypeptide 0.701
Itgal integrin alpha L 0.688
Traf6 TNF receptor-associated factor 6 0.686
Gli2 GLI-Kruppel family member GLI2 0.666
Stat5a signal transducer and activator of transcription 5A 0.646
Pdcd1 programmed cell death 1 0.645
Ubd ubiquitin D 0.645
H2-Eb1 histocompatibility 2, class II antigen E beta 0.644
Stat1 signal transducer and activator of transcription 1 0.635
Clec4d C-type lectin domain family 4, member d 0.633
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.626
Il12b interleukin 12b 0.615
Stat2 signal transducer and activator of transcription 2 0.588
Rb1 retinoblastoma 1 0.585
Ctnnb1 catenin (cadherin associated protein), beta 1 0.584
Igh immunoglobulin heavy chain complex 0.581
Foxc1 forkhead box C1 0.577
Ccr5 chemokine (C-C motif) receptor 5 0.577
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.567
Ccr2 chemokine (C-C motif) receptor 2 0.562
Xcl1 chemokine (C motif) ligand 1 0.547
Socs1 suppressor of cytokine signaling 1 0.539
Cd19 CD19 antigen 0.538
Sh2d2a SH2 domain protein 2A 0.531
Ntf3 neurotrophin 3 0.530
Trp53 transformation related protein 53 0.526
Cd7 CD7 antigen 0.514
Clec4n C-type lectin domain family 4, member n 0.512
Smad6 MAD homolog 6 (Drosophila) 0.510
Smad4 MAD homolog 4 (Drosophila) 0.505
Gbp5 guanylate binding protein 5 0.505
Traf2 TNF receptor-associated factor 2 0.504
Fasl Fas ligand (TNF superfamily, member 6) 0.496
Cyld cylindromatosis (turban tumor syndrome) 0.493
Nf1 neurofibromatosis 1 0.487
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.486
Il27ra interleukin 27 receptor, alpha 0.477
Il1rn interleukin 1 receptor antagonist 0.474
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.473
Cxcl9 chemokine (C-X-C motif) ligand 9 0.472
Il2rg interleukin 2 receptor, gamma chain 0.472
Birc3 baculoviral IAP repeat-containing 3 0.467
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.451
Irf9 interferon regulatory factor 9 0.451
Fyn Fyn proto-oncogene 0.444
Pthlh parathyroid hormone-like peptide 0.442
Ccl3 chemokine (C-C motif) ligand 3 0.435
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.430
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.428
Emx2 empty spiracles homolog 2 (Drosophila) 0.423
Cd86 CD86 antigen 0.423
Dok1 docking protein 1 0.421
Jag1 jagged 1 0.421
Mmp9 matrix metallopeptidase 9 0.410
Ptgs2 prostaglandin-endoperoxide synthase 2 0.409
Ccl8 chemokine (C-C motif) ligand 8 0.409
Il6 interleukin 6 0.406
Gli3 GLI-Kruppel family member GLI3 0.406
Vegfa vascular endothelial growth factor A 0.402
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.399
Il15ra interleukin 15 receptor, alpha chain 0.397
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.396
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.393
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HLA-DRA major histocompatibility complex, class II, DR alpha 0.987
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.982
CD80 CD80 molecule 0.982
BIRC3 baculoviral IAP repeat containing 3 0.982
LAT linker for activation of T cells 0.971
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.966
HLA-DMA major histocompatibility complex, class II, DM alpha 0.955
EGFR epidermal growth factor receptor 0.934
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.932
GRB2 growth factor receptor-bound protein 2 0.925
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.899
HLA-DMB major histocompatibility complex, class II, DM beta 0.893
CD86 CD86 molecule 0.892
ICAM1 intercellular adhesion molecule 1 0.871
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.856
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.853
SOCS3 suppressor of cytokine signaling 3 0.837
HLA-B major histocompatibility complex, class I, B 0.826
CXCL9 chemokine (C-X-C motif) ligand 9 0.825
B2M beta-2-microglobulin 0.798
HLA-E major histocompatibility complex, class I, E 0.747
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.724
HLA-G major histocompatibility complex, class I, G 0.702
TRAF1 TNF receptor-associated factor 1 0.673
BTN3A1 butyrophilin, subfamily 3, member A1 0.651
CD247 CD247 molecule 0.651
CCR7 chemokine (C-C motif) receptor 7 0.638
CCR5 chemokine (C-C motif) receptor 5 0.585
BIRC2 baculoviral IAP repeat containing 2 0.576
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.572
IL1R1 interleukin 1 receptor, type I 0.557
BTN3A3 butyrophilin, subfamily 3, member A3 0.552
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.542
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.537
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.536
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.521
IL2RG interleukin 2 receptor, gamma 0.519
CCL4 chemokine (C-C motif) ligand 4 0.502
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.487
BCL10 B-cell CLL/lymphoma 10 0.472
CD2 CD2 molecule 0.462
PTPRC protein tyrosine phosphatase, receptor type, C 0.455
CCL5 chemokine (C-C motif) ligand 5 0.453
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.446
SOS1 son of sevenless homolog 1 (Drosophila) 0.438
JAK2 Janus kinase 2 0.428
CXCL10 chemokine (C-X-C motif) ligand 10 0.421
HLA-A major histocompatibility complex, class I, A 0.404
CCR1 chemokine (C-C motif) receptor 1 0.389
CCL13 chemokine (C-C motif) ligand 13 0.371
HLA-F major histocompatibility complex, class I, F 0.367
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.366
ABI1 abl-interactor 1 0.365
CD163 CD163 molecule 0.364
BTN3A2 butyrophilin, subfamily 3, member A2 0.359
IL2RB interleukin 2 receptor, beta 0.359
CCL2 chemokine (C-C motif) ligand 2 0.345
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.345
PLCG1 phospholipase C, gamma 1 0.339
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.335
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.319
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.304
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.299
BMPR1A bone morphogenetic protein receptor, type IA 0.296
LCK lymphocyte-specific protein tyrosine kinase 0.272
JAK1 Janus kinase 1 0.259
CXCL2 chemokine (C-X-C motif) ligand 2 0.245
TNF tumor necrosis factor 0.238
CFLAR CASP8 and FADD-like apoptosis regulator 0.238
HK3 hexokinase 3 (white cell) 0.238
HLA-C major histocompatibility complex, class I, C 0.232
CD52 CD52 molecule 0.228
IL23A interleukin 23, alpha subunit p19 0.226
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.226
CCL22 chemokine (C-C motif) ligand 22 0.225
CCL8 chemokine (C-C motif) ligand 8 0.217
CCR2 chemokine (C-C motif) receptor 2 0.214
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.212
IL1R2 interleukin 1 receptor, type II 0.211
FSTL1 follistatin-like 1 0.203
CLEC10A C-type lectin domain family 10, member A 0.195
AIF1 allograft inflammatory factor 1 0.193
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.187
IL8 interleukin 8 0.180
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.173
AOAH acyloxyacyl hydrolase (neutrophil) 0.167
NLRP3 NLR family, pyrin domain containing 3 0.167
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.166
CD28 CD28 molecule 0.162
IL10 interleukin 10 0.161
SIGLEC7 sialic acid binding Ig-like lectin 7 0.161
IL1B interleukin 1, beta 0.156
IL6 interleukin 6 (interferon, beta 2) 0.154
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.153
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 0.151
CD6 CD6 molecule 0.144
FPR3 formyl peptide receptor 3 0.143
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.143
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.140
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.138
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.955
RT1-Da RT1 class II, locus Da 0.930
RT1-Bb RT1 class II, locus Bb 0.830
RT1-DMb RT1 class II, locus DMb 0.616
Cd37 CD37 molecule 0.590
RT1-Ba RT1 class II, locus Ba 0.575
RT1-Db1 RT1 class II, locus Db1 0.271
Cd53 Cd53 molecule 0.214
RT1-DMa RT1 class II, locus DMa 0.109
Ptprc protein tyrosine phosphatase, receptor type, C 0.103
Hck hemopoietic cell kinase 0.090
Cd44 Cd44 molecule 0.064
Laptm5 lysosomal protein transmembrane 5 0.064
Cd247 Cd247 molecule 0.061
Il18 interleukin 18 0.054
Lcp1 lymphocyte cytosolic protein 1 0.046
Casp1 caspase 1 0.035
Slfn2 schlafen 2 0.033
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.029
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.027
Aif1 allograft inflammatory factor 1 0.025
Ctss cathepsin S 0.021
Vom2r27 vomeronasal 2 receptor, 27 0.021
Il1b interleukin 1 beta 0.021
Arpc1b actin related protein 2/3 complex, subunit 1B 0.020
Icam1 intercellular adhesion molecule 1 0.020
Dock8 dedicator of cytokinesis 8 0.020
Prr13 proline rich 13 0.019
Scp2 sterol carrier protein 2 0.019
Lyz2 lysozyme 2 0.018
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.018
Ciita class II, major histocompatibility complex, transactivator 0.018
Cd2 Cd2 molecule 0.018
Plek pleckstrin 0.017
Capg capping protein (actin filament), gelsolin-like 0.017
Wipf1 WAS/WASL interacting protein family, member 1 0.017
Il2rb interleukin 2 receptor, beta 0.017
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.017
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.017
Il7r interleukin 7 receptor 0.016
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.015
Bin2 bridging integrator 2 0.015
Sla src-like adaptor 0.015
Rhog ras homolog gene family, member G (rho G) 0.015
Fgb fibrinogen beta chain 0.015
Cxcl10 chemokine (C-X-C motif) ligand 10 0.014
Arhgap4 Rho GTPase activating protein 4 0.014
Iapp islet amyloid polypeptide 0.014
Itgb7 integrin, beta 7 0.014
Fga fibrinogen alpha chain 0.014
Inpp5d inositol polyphosphate-5-phosphatase D 0.014
Sash3 SAM and SH3 domain containing 3 0.013
Il6 interleukin 6 0.013
Cfp complement factor properdin 0.012
Igh-6 immunoglobulin heavy chain 6 0.012
Spn sialophorin 0.012
Neurl3 neuralized homolog 3 (Drosophila) 0.012
Batf3 basic leucine zipper transcription factor, ATF-like 3 0.011
Taok1 TAO kinase 1 0.011
Grn granulin 0.011
Nfat5 nuclear factor of activated T-cells 5 0.011
Sorbs1 sorbin and SH3 domain containing 1 0.011
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.011
Jak2 Janus kinase 2 0.011
Ehf ets homologous factor 0.010
Cd5 Cd5 molecule 0.010
Zbp1 Z-DNA binding protein 1 0.010
Klf6 Kruppel-like factor 6 0.010
Pdzk1ip1 PDZK1 interacting protein 1 0.010
Ccl3 chemokine (C-C motif) ligand 3 0.010
Sell selectin L 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism