IMP

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Homo sapiens

46 genes annotated in human

Multi-species View

regulation of response to cytokine stimulus

GO:0060759

Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of response to cytokine stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of response to cytokine stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
IRAK1	interleukin-1 receptor-associated kinase 1	0.889
IRAK2	interleukin-1 receptor-associated kinase 2	0.642
LCK	lymphocyte-specific protein tyrosine kinase	0.568	Human
IL1R1	interleukin 1 receptor, type I	0.558
C1QA	complement component 1, q subcomponent, A chain	0.536	Human
MYD88	myeloid differentiation primary response gene (88)	0.507
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.476
ZNF43	zinc finger protein 43	0.469
TRAF6	TNF receptor-associated factor 6	0.445
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.440	Human
GRB2	growth factor receptor-bound protein 2	0.357
CCR5	chemokine (C-C motif) receptor 5	0.278
PML	promyelocytic leukemia	0.258
HCK	hemopoietic cell kinase	0.252	Human
DTX3L	deltex 3-like (Drosophila)	0.246
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.200
ZNF253	zinc finger protein 253	0.185
ZNF273	zinc finger protein 273	0.180	Human
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.171
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.159
SOCS3	suppressor of cytokine signaling 3	0.153
ZNF675	zinc finger protein 675	0.152
SYK	spleen tyrosine kinase	0.152
JAK2	Janus kinase 2	0.151
GHR	growth hormone receptor	0.119
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.112
GAS6	growth arrest-specific 6	0.100
TMEM173	transmembrane protein 173	0.098
FAS	Fas (TNF receptor superfamily, member 6)	0.093
SPRR2A	small proline-rich protein 2A	0.092
CCL4	chemokine (C-C motif) ligand 4	0.091	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.089
ZNF708	zinc finger protein 708	0.088	Human
SH3KBP1	SH3-domain kinase binding protein 1	0.087
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.081
RNF31	ring finger protein 31	0.081
C1QC	complement component 1, q subcomponent, C chain	0.080	Human
RXRA	retinoid X receptor, alpha	0.078
C19orf50	chromosome 19 open reading frame 50	0.075
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.073
ZNF91	zinc finger protein 91	0.073
RARA	retinoic acid receptor, alpha	0.071
NCOR2	nuclear receptor corepressor 2	0.070
DAXX	death-domain associated protein	0.065
UBASH3B	ubiquitin associated and SH3 domain containing B	0.060
PLCG1	phospholipase C, gamma 1	0.060
ZNF93	zinc finger protein 93	0.060
ZNF117	zinc finger protein 117	0.059	Human
AXL	AXL receptor tyrosine kinase	0.057
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.057
PTPRB	protein tyrosine phosphatase, receptor type, B	0.053
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.052
RUNX1	runt-related transcription factor 1	0.051
IRAK4	interleukin-1 receptor-associated kinase 4	0.049
IRF7	interferon regulatory factor 7	0.049	Mouse
ICAM1	intercellular adhesion molecule 1	0.047
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.046
TLR4	toll-like receptor 4	0.045
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.045
STAT4	signal transducer and activator of transcription 4	0.044
IL1RAP	interleukin 1 receptor accessory protein	0.044
APOC1	apolipoprotein C-I	0.044
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.044
ZNF680	zinc finger protein 680	0.044	Human
MAP2K5	mitogen-activated protein kinase kinase 5	0.043	Rat
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.043
C1QB	complement component 1, q subcomponent, B chain	0.043	Human
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.042	Human
ZNF430	zinc finger protein 430	0.042	Human
IDE	insulin-degrading enzyme	0.042
ZNF85	zinc finger protein 85	0.041	Human
CYLD	cylindromatosis (turban tumor syndrome)	0.041
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.040
ZNF107	zinc finger protein 107	0.040
NLRC4	NLR family, CARD domain containing 4	0.039
PELI3	pellino homolog 3 (Drosophila)	0.039
CXCL10	chemokine (C-X-C motif) ligand 10	0.038
ZNF254	zinc finger protein 254	0.038	Human
LAT	linker for activation of T cells	0.038
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.037	Human
NCK1	NCK adaptor protein 1	0.037
HP	haptoglobin	0.036
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.036
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.036
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.036
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.035
CAV2	caveolin 2	0.035
ATN1	atrophin 1	0.035
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.034
SQSTM1	sequestosome 1	0.033
CREBBP	CREB binding protein	0.032
CD14	CD14 molecule	0.032
FZD1	frizzled homolog 1 (Drosophila)	0.032
CCL7	chemokine (C-C motif) ligand 7	0.032	Human
CCR7	chemokine (C-C motif) receptor 7	0.031
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.031
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.031
ESR1	estrogen receptor 1	0.031
LIMD1	LIM domains containing 1	0.030
RIPK2	receptor-interacting serine-threonine kinase 2	0.030	Mouse
SKIL	SKI-like oncogene	0.030
MEFV	Mediterranean fever	0.029
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.029
STAT1	signal transducer and activator of transcription 1, 91kDa	0.029
LCAT	lecithin-cholesterol acyltransferase	0.029
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.029	Human
GAB1	GRB2-associated binding protein 1	0.027
PIAS4	protein inhibitor of activated STAT, 4	0.027
LTBP4	latent transforming growth factor beta binding protein 4	0.027
C1S	complement component 1, s subcomponent	0.026
IL1B	interleukin 1, beta	0.025	Human
ZNF92	zinc finger protein 92	0.025	Human
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.025
TGS1	trimethylguanosine synthase 1	0.025
TICAM1	toll-like receptor adaptor molecule 1	0.025
CCL3	chemokine (C-C motif) ligand 3	0.024	Human
BLNK	B-cell linker	0.024
HR	hairless homolog (mouse)	0.024
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.024
MAPK7	mitogen-activated protein kinase 7	0.023
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.023
PIAS1	protein inhibitor of activated STAT, 1	0.023
ZRANB1	zinc finger, RAN-binding domain containing 1	0.023
TLR2	toll-like receptor 2	0.023
NKG7	natural killer cell group 7 sequence	0.023
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.022
NOD2	nucleotide-binding oligomerization domain containing 2	0.022	Human
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.022
CCR1	chemokine (C-C motif) receptor 1	0.022
FASLG	Fas ligand (TNF superfamily, member 6)	0.021
JAK3	Janus kinase 3	0.021
A2M	alpha-2-macroglobulin	0.021
IL8	interleukin 8	0.021
NLRP3	NLR family, pyrin domain containing 3	0.021	Human
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.021
CPE	carboxypeptidase E	0.021
IRF5	interferon regulatory factor 5	0.021
ZNF682	zinc finger protein 682	0.021	Human
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.020
BTBD2	BTB (POZ) domain containing 2	0.020
OSMR	oncostatin M receptor	0.020	Human
PRKCQ	protein kinase C, theta	0.020
BIRC3	baculoviral IAP repeat containing 3	0.020
MED25	mediator complex subunit 25	0.020
CCL8	chemokine (C-C motif) ligand 8	0.020	Human
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.020
TOX4	TOX high mobility group box family member 4	0.020
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.020
TRAF1	TNF receptor-associated factor 1	0.019
CCL2	chemokine (C-C motif) ligand 2	0.019	Human
IRAK3	interleukin-1 receptor-associated kinase 3	0.019	Human
LNX1	ligand of numb-protein X 1	0.019
NCOA1	nuclear receptor coactivator 1	0.019
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.019
ENO2	enolase 2 (gamma, neuronal)	0.019
NOD1	nucleotide-binding oligomerization domain containing 1	0.019
NCOR1	nuclear receptor corepressor 1	0.019
TYMP	thymidine phosphorylase	0.018
RGS1	regulator of G-protein signaling 1	0.018
CD83	CD83 molecule	0.018
IL10	interleukin 10	0.018
MED28	mediator complex subunit 28	0.018
PIAS2	protein inhibitor of activated STAT, 2	0.017
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.017
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.017
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.017
ALB	albumin	0.017
RANBP9	RAN binding protein 9	0.017
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.017
ZNF506	zinc finger protein 506	0.017	Human
NELL2	NEL-like 2 (chicken)	0.017
PRKD2	protein kinase D2	0.017
PTEN	phosphatase and tensin homolog	0.017
CSF1	colony stimulating factor 1 (macrophage)	0.017
IL6	interleukin 6 (interferon, beta 2)	0.017
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.017
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.017
MARCO	macrophage receptor with collagenous structure	0.016
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.016
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.016
CNTF	ciliary neurotrophic factor	0.016
PLTP	phospholipid transfer protein	0.016
LRP6	low density lipoprotein receptor-related protein 6	0.016
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.016
IRS1	insulin receptor substrate 1	0.016
APOE	apolipoprotein E	0.016	Human
TNF	tumor necrosis factor	0.016
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.016
C5AR1	complement component 5a receptor 1	0.016
EP300	E1A binding protein p300	0.016
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.016
JAG2	jagged 2	0.016
PPARA	peroxisome proliferator-activated receptor alpha	0.016	Human
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.016
CFLAR	CASP8 and FADD-like apoptosis regulator	0.015
SLC15A3	solute carrier family 15, member 3	0.015
TBK1	TANK-binding kinase 1	0.015
FPR3	formyl peptide receptor 3	0.015
CD247	CD247 molecule	0.015
CD40	CD40 molecule, TNF receptor superfamily member 5	0.015
MTF2	metal response element binding transcription factor 2	0.015
TNPO1	transportin 1	0.015
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.015
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.015
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.015
LEPR	leptin receptor	0.015
APOC2	apolipoprotein C-II	0.014
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.014
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.014	Human
CLIP1	CAP-GLY domain containing linker protein 1	0.014
EGFR	epidermal growth factor receptor	0.014
HNF4A	hepatocyte nuclear factor 4, alpha	0.014
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.014
TREM2	triggering receptor expressed on myeloid cells 2	0.014
IL6R	interleukin 6 receptor	0.014
TGFA	transforming growth factor, alpha	0.014
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.014
VAV1	vav 1 guanine nucleotide exchange factor	0.014
IL1R2	interleukin 1 receptor, type II	0.014
SETD7	SET domain containing (lysine methyltransferase) 7	0.014
STAB1	stabilin 1	0.014
INHBA	inhibin, beta A	0.014
TBP	TATA box binding protein	0.014
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.014
APOC3	apolipoprotein C-III	0.014
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.014
SHARPIN	SHANK-associated RH domain interactor	0.014
FTH1	ferritin, heavy polypeptide 1	0.013
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.013
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.013
PGR	progesterone receptor	0.013
ZC3H12A	zinc finger CCCH-type containing 12A	0.013
MAPK8	mitogen-activated protein kinase 8	0.013
SH2D2A	SH2 domain containing 2A	0.013
CXCR4	chemokine (C-X-C motif) receptor 4	0.013
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.013
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.013
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.013	Human
CH25H	cholesterol 25-hydroxylase	0.013
CCL20	chemokine (C-C motif) ligand 20	0.013	Human
TGIF1	TGFB-induced factor homeobox 1	0.013
CXCL13	chemokine (C-X-C motif) ligand 13	0.013
TRIM21	tripartite motif containing 21	0.013
OSM	oncostatin M	0.013
LIMK2	LIM domain kinase 2	0.013
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.013
PLEK	pleckstrin	0.013
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.013
TEK	TEK tyrosine kinase, endothelial	0.013
WIPF1	WAS/WASL interacting protein family, member 1	0.013
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.013
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.013
OASL	2'-5'-oligoadenylate synthetase-like	0.013
ZNF493	zinc finger protein 493	0.012
GNLY	granulysin	0.012
ANGPT2	angiopoietin 2	0.012
C3	complement component 3	0.012
GRB7	growth factor receptor-bound protein 7	0.012
ZNF136	zinc finger protein 136	0.012
CXCL11	chemokine (C-X-C motif) ligand 11	0.012
PTGES	prostaglandin E synthase	0.012
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.012
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.012
FBLN1	fibulin 1	0.012
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.012
DUSP1	dual specificity phosphatase 1	0.012
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.012
RANGAP1	Ran GTPase activating protein 1	0.012
SMAD3	SMAD family member 3	0.012
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.012
THBS1	thrombospondin 1	0.012
MSR1	macrophage scavenger receptor 1	0.012
TREM1	triggering receptor expressed on myeloid cells 1	0.012
ANG	angiogenin, ribonuclease, RNase A family, 5	0.012
FAM3A	family with sequence similarity 3, member A	0.012
PICK1	protein interacting with PRKCA 1	0.012
ASRGL1	asparaginase like 1	0.012
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.012
EMP1	epithelial membrane protein 1	0.012
SPRY4	sprouty homolog 4 (Drosophila)	0.012
PDCD6	programmed cell death 6	0.012
GAS7	growth arrest-specific 7	0.012
ITK	IL2-inducible T-cell kinase	0.012
ITGA1	integrin, alpha 1	0.012
PARP14	poly (ADP-ribose) polymerase family, member 14	0.012	Human
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.012
ELK1	ELK1, member of ETS oncogene family	0.012
CXCL5	chemokine (C-X-C motif) ligand 5	0.012
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.012
HECTD3	HECT domain containing 3	0.012
DARC	Duffy blood group, chemokine receptor	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
VCAM1	vascular cell adhesion molecule 1	0.011
BCL2A1	BCL2-related protein A1	0.011
CTBP1	C-terminal binding protein 1	0.011
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.011
AIP	aryl hydrocarbon receptor interacting protein	0.011
NRG1	neuregulin 1	0.011
AFF4	AF4/FMR2 family, member 4	0.011
MTMR4	myotubularin related protein 4	0.011
APBA3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.011
CTSW	cathepsin W	0.011
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.011
TPSB2	tryptase beta 2 (gene/pseudogene)	0.011
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.011
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.011
CARD11	caspase recruitment domain family, member 11	0.011
VAV3	vav 3 guanine nucleotide exchange factor	0.011
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.011
VRK2	vaccinia related kinase 2	0.011
CD79B	CD79b molecule, immunoglobulin-associated beta	0.011
NCOA3	nuclear receptor coactivator 3	0.011
MBD4	methyl-CpG binding domain protein 4	0.011
RHOB	ras homolog gene family, member B	0.011
NNMT	nicotinamide N-methyltransferase	0.011
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.011
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.011
SECTM1	secreted and transmembrane 1	0.011
TP63	tumor protein p63	0.011
IRF9	interferon regulatory factor 9	0.011
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.011
TRIM27	tripartite motif containing 27	0.011
ZNF195	zinc finger protein 195	0.011	Human
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.011	Human
MAGEA2	melanoma antigen family A, 2	0.011
IL7R	interleukin 7 receptor	0.011
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.011
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.011
IL32	interleukin 32	0.011
TNC	tenascin C	0.011
TNS4	tensin 4	0.011
IFNG	interferon, gamma	0.011
PLXNB1	plexin B1	0.011
ZNF320	zinc finger protein 320	0.011
KALRN	kalirin, RhoGEF kinase	0.011
ZNF138	zinc finger protein 138	0.011
GRB10	growth factor receptor-bound protein 10	0.011
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.011
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.011
GPR84	G protein-coupled receptor 84	0.011
CCR3	chemokine (C-C motif) receptor 3	0.011
ATM	ataxia telangiectasia mutated	0.011
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.011	Human
RNASE1	ribonuclease, RNase A family, 1 (pancreatic)	0.010
SOCS1	suppressor of cytokine signaling 1	0.010	Zebrafish
MDFI	MyoD family inhibitor	0.010
PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285	0.010
PRKCDBP	protein kinase C, delta binding protein	0.010
PIM1	pim-1 oncogene	0.010
AVPR2	arginine vasopressin receptor 2	0.010
PINK1	PTEN induced putative kinase 1	0.010
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.010
FAM108A1	family with sequence similarity 108, member A1	0.010
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.010
ZNF100	zinc finger protein 100	0.010	Human
CD69	CD69 molecule	0.010
XPO1	exportin 1 (CRM1 homolog, yeast)	0.010
IPO13	importin 13	0.010
SLAMF8	SLAM family member 8	0.010
AQP9	aquaporin 9	0.010
XPO7	exportin 7	0.010
FAM83C	family with sequence similarity 83, member C	0.010
MMP19	matrix metallopeptidase 19	0.010
EPOR	erythropoietin receptor	0.010
GSDMD	gasdermin D	0.010
RAD54L2	RAD54-like 2 (S. cerevisiae)	0.010
SLA	Src-like-adaptor	0.010