Process View
Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cellular response to insulin stimulus"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Lepr | leptin receptor | 1.000 | ||
Insr | insulin receptor | 0.989 | ||
Fyn | Fyn proto-oncogene | 0.911 | ||
Ldb3 | LIM domain binding 3 | 0.889 | ||
Jak2 | Janus kinase 2 | 0.828 | ||
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.699 | ||
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.631 | ||
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.534 | ||
Lep | leptin | 0.530 | ||
Ar | androgen receptor | 0.519 | ||
Irs2 | insulin receptor substrate 2 | 0.493 | ||
Apc | adenomatosis polyposis coli | 0.385 | ||
Kit | kit oncogene | 0.322 | ||
Cish | cytokine inducible SH2-containing protein | 0.279 | Mouse | |
Igf1r | insulin-like growth factor I receptor | 0.276 | ||
Grb2 | growth factor receptor bound protein 2 | 0.276 | ||
Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.272 | ||
Jak1 | Janus kinase 1 | 0.265 | ||
Pparg | peroxisome proliferator activated receptor gamma | 0.261 | ||
Tek | endothelial-specific receptor tyrosine kinase | 0.253 | ||
Src | Rous sarcoma oncogene | 0.246 | ||
Vhl | von Hippel-Lindau tumor suppressor | 0.238 | ||
Ghr | growth hormone receptor | 0.216 | ||
Nf2 | neurofibromatosis 2 | 0.211 | ||
Stat5b | signal transducer and activator of transcription 5B | 0.211 | ||
Lipe | lipase, hormone sensitive | 0.206 | ||
Stat3 | signal transducer and activator of transcription 3 | 0.201 | ||
Cav1 | caveolin 1, caveolae protein | 0.201 | ||
Nf1 | neurofibromatosis 1 | 0.200 | ||
Pnpla2 | patatin-like phospholipase domain containing 2 | 0.195 | ||
Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.190 | ||
Nsf | N-ethylmaleimide sensitive fusion protein | 0.183 | ||
Bcl2 | B-cell leukemia/lymphoma 2 | 0.166 | ||
Plcg1 | phospholipase C, gamma 1 | 0.160 | ||
Esr1 | estrogen receptor 1 (alpha) | 0.156 | ||
Plin1 | perilipin 1 | 0.140 | ||
Tgfb1 | transforming growth factor, beta 1 | 0.132 | ||
Stat5a | signal transducer and activator of transcription 5A | 0.122 | ||
Socs2 | suppressor of cytokine signaling 2 | 0.121 | Mouse | |
Il1b | interleukin 1 beta | 0.120 | ||
Dok1 | docking protein 1 | 0.119 | ||
Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.115 | ||
Il6st | interleukin 6 signal transducer | 0.107 | ||
Foxo1 | forkhead box O1 | 0.106 | Fly | |
Fxr1 | fragile X mental retardation gene 1, autosomal homolog | 0.104 | Fly | |
Fmr1 | fragile X mental retardation syndrome 1 homolog | 0.096 | Fly | |
Ncoa3 | nuclear receptor coactivator 3 | 0.095 | ||
Prkce | protein kinase C, epsilon | 0.093 | Mouse | |
Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.092 | ||
Vav1 | vav 1 oncogene | 0.092 | ||
Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.088 | ||
Nos1 | nitric oxide synthase 1, neuronal | 0.088 | ||
Cd28 | CD28 antigen | 0.084 | ||
Phf1 | PHD finger protein 1 | 0.082 | ||
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.081 | ||
Rxra | retinoid X receptor alpha | 0.080 | ||
Smad3 | MAD homolog 3 (Drosophila) | 0.079 | ||
Vasp | vasodilator-stimulated phosphoprotein | 0.073 | ||
Csf1 | colony stimulating factor 1 (macrophage) | 0.072 | ||
Npc1 | Niemann Pick type C1 | 0.071 | ||
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.065 | ||
Il1a | interleukin 1 alpha | 0.064 | Mouse | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.064 | ||
Akt1 | thymoma viral proto-oncogene 1 | 0.064 | Mouse | |
Pag1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.063 | ||
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.063 | ||
Tnf | tumor necrosis factor | 0.058 | ||
Vav3 | vav 3 oncogene | 0.057 | ||
Thrb | thyroid hormone receptor beta | 0.053 | ||
Cbl | Casitas B-lineage lymphoma | 0.051 | ||
Gcgr | glucagon receptor | 0.050 | ||
Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.047 | ||
Vav2 | vav 2 oncogene | 0.047 | ||
Ep300 | E1A binding protein p300 | 0.045 | ||
Mark2 | MAP/microtubule affinity-regulating kinase 2 | 0.045 | ||
Apoe | apolipoprotein E | 0.045 | ||
Egfr | epidermal growth factor receptor | 0.044 | ||
Irs1 | insulin receptor substrate 1 | 0.043 | Rat | |
Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.043 | ||
Socs3 | suppressor of cytokine signaling 3 | 0.043 | ||
Mapkapk2 | MAP kinase-activated protein kinase 2 | 0.042 | ||
Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.042 | ||
Dok2 | docking protein 2 | 0.042 | ||
Rint1 | RAD50 interactor 1 | 0.042 | ||
Gsk3b | glycogen synthase kinase 3 beta | 0.042 | ||
Ubc | ubiquitin C | 0.041 | ||
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.041 | ||
Kiss1 | KiSS-1 metastasis-suppressor | 0.041 | ||
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.041 | ||
Ctdsp2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.038 | ||
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.037 | ||
Blnk | B-cell linker | 0.037 | ||
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.036 | ||
Plxna1 | plexin A1 | 0.036 | ||
Htt | huntingtin | 0.036 | ||
Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.035 | ||
Prkab1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.035 | ||
Nr1h4 | nuclear receptor subfamily 1, group H, member 4 | 0.035 | Mouse | |
Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.034 | ||
Efnb1 | ephrin B1 | 0.033 | ||
Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.033 | ||
Irak4 | interleukin-1 receptor-associated kinase 4 | 0.033 | ||
Crb2 | crumbs homolog 2 (Drosophila) | 0.033 | ||
Lck | lymphocyte protein tyrosine kinase | 0.032 | ||
Cul5 | cullin 5 | 0.032 | ||
Clock | circadian locomotor output cycles kaput | 0.032 | ||
Tcra | T-cell receptor alpha chain | 0.030 | ||
Rab25 | RAB25, member RAS oncogene family | 0.029 | ||
Gck | glucokinase | 0.029 | ||
Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.029 | ||
Shc1 | src homology 2 domain-containing transforming protein C1 | 0.029 | ||
Xpa | xeroderma pigmentosum, complementation group A | 0.029 | ||
Nos3 | nitric oxide synthase 3, endothelial cell | 0.028 | ||
Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.028 | ||
Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.028 | ||
Khdrbs1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.028 | ||
Rora | RAR-related orphan receptor alpha | 0.028 | ||
Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.027 | ||
Ezh1 | enhancer of zeste homolog 1 (Drosophila) | 0.027 | ||
Pim1 | proviral integration site 1 | 0.027 | ||
Mefv | Mediterranean fever | 0.026 | ||
Abcc6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 0.026 | ||
Csnk1d | casein kinase 1, delta | 0.026 | ||
Foxo4 | forkhead box O4 | 0.026 | Fly | |
Ptpre | protein tyrosine phosphatase, receptor type, E | 0.025 | ||
Prkca | protein kinase C, alpha | 0.025 | ||
Trp53 | transformation related protein 53 | 0.025 | ||
Fgfr3 | fibroblast growth factor receptor 3 | 0.025 | ||
Npy1r | neuropeptide Y receptor Y1 | 0.024 | ||
Prlr | prolactin receptor | 0.024 | ||
Cenpc1 | centromere protein C1 | 0.024 | ||
Nedd4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.024 | ||
Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.024 | ||
Spnb3 | spectrin beta 3 | 0.024 | ||
Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.024 | ||
Ptpn12 | protein tyrosine phosphatase, non-receptor type 12 | 0.023 | ||
Pten | phosphatase and tensin homolog | 0.023 | ||
Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.023 | ||
Spred1 | sprouty protein with EVH-1 domain 1, related sequence | 0.023 | ||
Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.023 | ||
Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.023 | ||
Mark4 | MAP/microtubule affinity-regulating kinase 4 | 0.023 | ||
Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 0.023 | ||
Il1r1 | interleukin 1 receptor, type I | 0.023 | ||
Egr1 | early growth response 1 | 0.022 | ||
Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.022 | ||
Akt2 | thymoma viral proto-oncogene 2 | 0.022 | Mouse | |
Foxa2 | forkhead box A2 | 0.022 | ||
Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.022 | ||
Lat | linker for activation of T cells | 0.021 | ||
Adra1b | adrenergic receptor, alpha 1b | 0.021 | ||
Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | 0.021 | ||
Gpd2 | glycerol phosphate dehydrogenase 2, mitochondrial | 0.021 | ||
Wdfy2 | WD repeat and FYVE domain containing 2 | 0.021 | ||
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.021 | ||
Ggnbp1 | gametogenetin binding protein 1 | 0.021 | ||
Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.020 | ||
Pik3c2a | phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide | 0.020 | ||
Agtr1a | angiotensin II receptor, type 1a | 0.020 | ||
Fbxw7 | F-box and WD-40 domain protein 7 | 0.020 | ||
Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.020 | ||
Hsf1 | heat shock factor 1 | 0.020 | ||
Phlpp1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.019 | ||
Sik3 | SIK family kinase 3 | 0.019 | ||
Epn1 | epsin 1 | 0.019 | ||
Fbxl20 | F-box and leucine-rich repeat protein 20 | 0.019 | ||
Bcar1 | breast cancer anti-estrogen resistance 1 | 0.019 | ||
Axin1 | axin 1 | 0.019 | ||
Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.019 | ||
Spp1 | secreted phosphoprotein 1 | 0.019 | ||
Mapk8 | mitogen-activated protein kinase 8 | 0.019 | ||
Asprv1 | aspartic peptidase, retroviral-like 1 | 0.019 | ||
Ate1 | arginyltransferase 1 | 0.019 | ||
Itsn1 | intersectin 1 (SH3 domain protein 1A) | 0.019 | ||
Ly6g6c | lymphocyte antigen 6 complex, locus G6C | 0.019 | ||
Fto | fat mass and obesity associated | 0.018 | ||
Csnk1g2 | casein kinase 1, gamma 2 | 0.018 | ||
Per2 | period homolog 2 (Drosophila) | 0.018 | ||
Crb3 | crumbs homolog 3 (Drosophila) | 0.018 | ||
Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.018 | ||
Prkag1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.018 | ||
Agap3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 | 0.018 | ||
Fgf21 | fibroblast growth factor 21 | 0.018 | ||
Rps6ka3 | ribosomal protein S6 kinase polypeptide 3 | 0.017 | ||
Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.017 | ||
Socs6 | suppressor of cytokine signaling 6 | 0.017 | Mouse | |
Klc2 | kinesin light chain 2 | 0.017 | ||
Azgp1 | alpha-2-glycoprotein 1, zinc | 0.017 | ||
Mxd1 | MAX dimerization protein 1 | 0.017 | ||
Fzd8 | frizzled homolog 8 (Drosophila) | 0.017 | ||
Kitl | kit ligand | 0.017 | ||
Actn2 | actinin alpha 2 | 0.017 | ||
Bcl3 | B-cell leukemia/lymphoma 3 | 0.016 | ||
Ptger4 | prostaglandin E receptor 4 (subtype EP4) | 0.016 | ||
Mib1 | mindbomb homolog 1 (Drosophila) | 0.016 | ||
Rapgef3 | Rap guanine nucleotide exchange factor (GEF) 3 | 0.016 | ||
Homer1 | homer homolog 1 (Drosophila) | 0.016 | ||
Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.016 | ||
Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.016 | ||
Myh14 | myosin, heavy polypeptide 14 | 0.016 | ||
Notch1 | Notch gene homolog 1 (Drosophila) | 0.016 | ||
Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.016 | ||
Efnb2 | ephrin B2 | 0.016 | ||
Rdh16 | retinol dehydrogenase 16 | 0.016 | ||
Ldb1 | LIM domain binding 1 | 0.016 | ||
Cand1 | cullin associated and neddylation disassociated 1 | 0.016 | ||
Atxn1 | ataxin 1 | 0.016 | ||
Thra | thyroid hormone receptor alpha | 0.016 | ||
Ptprn | protein tyrosine phosphatase, receptor type, N | 0.016 | ||
Taz | tafazzin | 0.015 | ||
Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.015 | ||
Ank | progressive ankylosis | 0.015 | ||
Rab17 | RAB17, member RAS oncogene family | 0.015 | ||
Creb1 | cAMP responsive element binding protein 1 | 0.015 | ||
Fam83f | family with sequence similarity 83, member F | 0.015 | ||
Tead3 | TEA domain family member 3 | 0.015 | ||
Hr | hairless | 0.014 | ||
Mtch1 | mitochondrial carrier homolog 1 (C. elegans) | 0.014 | ||
Nfe2l1 | nuclear factor, erythroid derived 2,-like 1 | 0.014 | ||
G0s2 | G0/G1 switch gene 2 | 0.014 | ||
Gdf15 | growth differentiation factor 15 | 0.014 | ||
Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.014 | ||
Rap1gap | Rap1 GTPase-activating protein | 0.014 | ||
Nedd4l | neural precursor cell expressed, developmentally down-regulated gene 4-like | 0.014 | ||
Fgf1 | fibroblast growth factor 1 | 0.014 | ||
Lrrc8c | leucine rich repeat containing 8 family, member C | 0.014 | ||
Mllt1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 0.014 | ||
Braf | Braf transforming gene | 0.014 | ||
Man1a2 | mannosidase, alpha, class 1A, member 2 | 0.013 | ||
C3 | complement component 3 | 0.013 | ||
Trim46 | tripartite motif-containing 46 | 0.013 | ||
Arf3 | ADP-ribosylation factor 3 | 0.013 | ||
Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.013 | ||
Itga1 | integrin alpha 1 | 0.013 | ||
Clip2 | CAP-GLY domain containing linker protein 2 | 0.013 | ||
Dlg3 | discs, large homolog 3 (Drosophila) | 0.013 | ||
Cd44 | CD44 antigen | 0.013 | ||
Wipf1 | WAS/WASL interacting protein family, member 1 | 0.013 | ||
Ftsjd1 | FtsJ methyltransferase domain containing 1 | 0.013 | ||
Smad5 | MAD homolog 5 (Drosophila) | 0.013 | ||
Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.013 | ||
Sh2b3 | SH2B adaptor protein 3 | 0.013 | ||
Plin4 | perilipin 4 | 0.013 | ||
Il1f9 | interleukin 1 family, member 9 | 0.013 | ||
Rcan1 | regulator of calcineurin 1 | 0.013 | ||
Frs2 | fibroblast growth factor receptor substrate 2 | 0.012 | ||
Usp42 | ubiquitin specific peptidase 42 | 0.012 | ||
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.012 | ||
Lsm14a | LSM14 homolog A (SCD6, S. cerevisiae) | 0.012 | ||
Skil | SKI-like | 0.012 | ||
Hif3a | hypoxia inducible factor 3, alpha subunit | 0.012 | ||
Atg2a | ATG2 autophagy related 2 homolog A (S. cerevisiae) | 0.012 | ||
Akr1b7 | aldo-keto reductase family 1, member B7 | 0.012 | ||
Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.012 | ||
Nck2 | non-catalytic region of tyrosine kinase adaptor protein 2 | 0.012 | Fly | |
Myh10 | myosin, heavy polypeptide 10, non-muscle | 0.012 | ||
Pdzk1ip1 | PDZK1 interacting protein 1 | 0.012 | ||
Arrdc3 | arrestin domain containing 3 | 0.012 | ||
Notch2 | Notch gene homolog 2 (Drosophila) | 0.012 | ||
Junb | Jun-B oncogene | 0.011 | ||
Cops2 | COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) | 0.011 | ||
Adipoq | adiponectin, C1Q and collagen domain containing | 0.011 | ||
Kiss1r | KISS1 receptor | 0.011 | ||
Arrb2 | arrestin, beta 2 | 0.011 | ||
Epas1 | endothelial PAS domain protein 1 | 0.011 | ||
Mocs1 | molybdenum cofactor synthesis 1 | 0.011 | ||
Nos2 | nitric oxide synthase 2, inducible | 0.011 | ||
AI118078 | expressed sequence AI118078 | 0.011 | ||
Zbtb41 | zinc finger and BTB domain containing 41 homolog | 0.011 | ||
Alms1 | Alstrom syndrome 1 homolog (human) | 0.011 | ||
Bcl6 | B-cell leukemia/lymphoma 6 | 0.011 | ||
Usf2 | upstream transcription factor 2 | 0.011 | ||
Adora2a | adenosine A2a receptor | 0.011 | ||
Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.011 | ||
Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.011 | ||
Rap2a | RAS related protein 2a | 0.011 | ||
Enah | enabled homolog (Drosophila) | 0.011 | ||
Lrig1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.011 | ||
Casp1 | caspase 1 | 0.011 | ||
Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.011 | ||
Ccndbp1 | cyclin D-type binding-protein 1 | 0.011 | ||
Aff1 | AF4/FMR2 family, member 1 | 0.011 | ||
Hivep2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.011 | ||
Tgfbr1 | transforming growth factor, beta receptor I | 0.011 | ||
Irg1 | immunoresponsive gene 1 | 0.011 | ||
Cyp2b10 | cytochrome P450, family 2, subfamily b, polypeptide 10 | 0.011 | ||
Ngef | neuronal guanine nucleotide exchange factor | 0.011 | ||
Iyd | iodotyrosine deiodinase | 0.011 | ||
Eif2a | eukaryotic translation initiation factor 2A | 0.010 | ||
Igf1 | insulin-like growth factor 1 | 0.010 | ||
Fzd7 | frizzled homolog 7 (Drosophila) | 0.010 | ||
Fam83h | family with sequence similarity 83, member H | 0.010 | ||
C77080 | expressed sequence C77080 | 0.010 | ||
Cyld | cylindromatosis (turban tumor syndrome) | 0.010 | ||
Rxrg | retinoid X receptor gamma | 0.010 | ||
Nr1i2 | nuclear receptor subfamily 1, group I, member 2 | 0.010 | Mouse | |
Plxnc1 | plexin C1 | 0.010 | ||
4933407C03Rik | RIKEN cDNA 4933407C03 gene | 0.010 | ||
Alkbh1 | alkB, alkylation repair homolog 1 (E. coli) | 0.010 | ||
Dpysl2 | dihydropyrimidinase-like 2 | 0.010 | ||
Slc22a18 | solute carrier family 22 (organic cation transporter), member 18 | 0.010 | ||
Fosl2 | fos-like antigen 2 | 0.010 | ||
Per1 | period homolog 1 (Drosophila) | 0.010 | ||
Axin2 | axin2 | 0.010 | ||
Trp53bp2 | transformation related protein 53 binding protein 2 | 0.010 | ||
Sim1 | single-minded homolog 1 (Drosophila) | 0.010 | ||
Ythdc2 | YTH domain containing 2 | 0.010 |