IMP

Process View

Mus musculus

35 genes annotated in mouse

t cell homeostasis

The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "t cell homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
Foxp3	forkhead box P3	0.990
Stat3	signal transducer and activator of transcription 3	0.985	Mouse
Trp53	transformation related protein 53	0.980
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.933
Bax	BCL2-associated X protein	0.879
Casp8	caspase 8	0.792	Mouse
Cd19	CD19 antigen	0.723
Fas	Fas (TNF receptor superfamily member 6)	0.641
Mcl1	myeloid cell leukemia sequence 1	0.581	Mouse
Irf9	interferon regulatory factor 9	0.565
Stat5a	signal transducer and activator of transcription 5A	0.488
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.444	Mouse
Myd88	myeloid differentiation primary response gene 88	0.426
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.392
Cdk1	cyclin-dependent kinase 1	0.374
Il1r1	interleukin 1 receptor, type I	0.332
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.299	Mouse
Stat5b	signal transducer and activator of transcription 5B	0.295
Tlr4	toll-like receptor 4	0.286
Kit	kit oncogene	0.277
Casp1	caspase 1	0.262	Mouse
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.259
Rc3h1	RING CCCH (C3H) domains 1	0.222
Tgfb1	transforming growth factor, beta 1	0.201
Il2	interleukin 2	0.199
Lyz2	lysozyme 2	0.192
Igh	immunoglobulin heavy chain complex	0.184
Fadd	Fas (TNFRSF6)-associated via death domain	0.161
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.160
Bcl2	B-cell leukemia/lymphoma 2	0.153
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.151
Socs1	suppressor of cytokine signaling 1	0.146
Il10	interleukin 10	0.139
Prf1	perforin 1 (pore forming protein)	0.135
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.128
Jak2	Janus kinase 2	0.125	Mouse
Tnf	tumor necrosis factor	0.121
Stat6	signal transducer and activator of transcription 6	0.111	Mouse
Bak1	BCL2-antagonist/killer 1	0.109	Mouse
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.105
Ttc7	tetratricopeptide repeat domain 7	0.099
Il6st	interleukin 6 signal transducer	0.099
Prc1	protein regulator of cytokinesis 1	0.096
Rxra	retinoid X receptor alpha	0.090
Tnip1	TNFAIP3 interacting protein 1	0.088
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.087
Gbp5	guanylate binding protein 5	0.087
Pycard	PYD and CARD domain containing	0.085
Ticam1	toll-like receptor adaptor molecule 1	0.079
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.078
Batf	basic leucine zipper transcription factor, ATF-like	0.074
Traf6	TNF receptor-associated factor 6	0.070
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.068
Il18	interleukin 18	0.068
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.067
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.066
Wdr1	WD repeat domain 1	0.063
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.063
Ripk3	receptor-interacting serine-threonine kinase 3	0.059
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.059
Casp7	caspase 7	0.058	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.058
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.058	Mouse
Arpc4	actin related protein 2/3 complex, subunit 4	0.056
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.056
Ghr	growth hormone receptor	0.056
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.055	Mouse
Lyst	lysosomal trafficking regulator	0.055
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.053
Rag2	recombination activating gene 2	0.052
Hif1a	hypoxia inducible factor 1, alpha subunit	0.051
Traf1	TNF receptor-associated factor 1	0.050
Ifnar1	interferon (alpha and beta) receptor 1	0.050
Il6	interleukin 6	0.049
Akt2	thymoma viral proto-oncogene 2	0.049
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.049
Cyld	cylindromatosis (turban tumor syndrome)	0.048
Prlr	prolactin receptor	0.046
Dbnl	drebrin-like	0.045
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.044
Ptgs2	prostaglandin-endoperoxide synthase 2	0.043
Il4ra	interleukin 4 receptor, alpha	0.042
Pdcd1	programmed cell death 1	0.041
Apc	adenomatosis polyposis coli	0.041
Ncoa3	nuclear receptor coactivator 3	0.041
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.039
Bid	BH3 interacting domain death agonist	0.037
Zfp36	zinc finger protein 36	0.037
Rara	retinoic acid receptor, alpha	0.036
Ikbkg	inhibitor of kappaB kinase gamma	0.036
Ly96	lymphocyte antigen 96	0.036
Cdk4	cyclin-dependent kinase 4	0.036
Mapkap1	mitogen-activated protein kinase associated protein 1	0.035
Zeb1	zinc finger E-box binding homeobox 1	0.034
Pten	phosphatase and tensin homolog	0.034
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.034
Aim2	absent in melanoma 2	0.033
Trim21	tripartite motif-containing 21	0.033
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.033
Capzb	capping protein (actin filament) muscle Z-line, beta	0.033
Trim62	tripartite motif-containing 62	0.032
Jak1	Janus kinase 1	0.032	Mouse
Vasp	vasodilator-stimulated phosphoprotein	0.032
Lepr	leptin receptor	0.032
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.030
Bcl6	B-cell leukemia/lymphoma 6	0.030
Ptp4a2	protein tyrosine phosphatase 4a2	0.030
Pparg	peroxisome proliferator activated receptor gamma	0.029
Tmem173	transmembrane protein 173	0.029
Tcrb	T-cell receptor beta chain	0.029
Birc3	baculoviral IAP repeat-containing 3	0.028
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.028
Capn1	calpain 1	0.028
Lep	leptin	0.028
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.028
Ctsz	cathepsin Z	0.027
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.027
Ifng	interferon gamma	0.026
Apaf1	apoptotic peptidase activating factor 1	0.026
Inpp5d	inositol polyphosphate-5-phosphatase D	0.026
Stx11	syntaxin 11	0.026
Ikzf1	IKAROS family zinc finger 1	0.026
Tcrd	T-cell receptor delta chain	0.026
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.025
Clic1	chloride intracellular channel 1	0.025
Msn	moesin	0.024
Rac1	RAS-related C3 botulinum substrate 1	0.024
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.024
Ar	androgen receptor	0.024
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.023
Ikzf2	IKAROS family zinc finger 2	0.023
Vhl	von Hippel-Lindau tumor suppressor	0.023
Irf8	interferon regulatory factor 8	0.023
Ccr4	chemokine (C-C motif) receptor 4	0.023
Litaf	LPS-induced TN factor	0.022
Nfil3	nuclear factor, interleukin 3, regulated	0.022
Bbc3	BCL2 binding component 3	0.022
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.021	Mouse
Casp3	caspase 3	0.021
Ahr	aryl-hydrocarbon receptor	0.021
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.021
Esr1	estrogen receptor 1 (alpha)	0.021
Bcl2l1	BCL2-like 1	0.020	Mouse
Trim55	tripartite motif-containing 55	0.020
Zfp26	zinc finger protein 26	0.020
B9d2	B9 protein domain 2	0.020
Gata1	GATA binding protein 1	0.020
Pold4	polymerase (DNA-directed), delta 4	0.019
4933426M11Rik	RIKEN cDNA 4933426M11 gene	0.019
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.019
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.019
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.019
Tmpo	thymopoietin	0.019
Was	Wiskott-Aldrich syndrome homolog (human)	0.019
Wwox	WW domain-containing oxidoreductase	0.019
Adar	adenosine deaminase, RNA-specific	0.019
Cxcr4	chemokine (C-X-C motif) receptor 4	0.019
Cd274	CD274 antigen	0.018
Nckap1l	NCK associated protein 1 like	0.018
Rc3h2	ring finger and CCCH-type zinc finger domains 2	0.018
Slurp1	secreted Ly6/Plaur domain containing 1	0.018
Runx1	runt related transcription factor 1	0.018
Ogfr	opioid growth factor receptor	0.017
Il3	interleukin 3	0.017
Lgals9	lectin, galactose binding, soluble 9	0.017
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.017
Mlkl	mixed lineage kinase domain-like	0.017
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.017
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.017
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.017
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.017
Mapk8	mitogen-activated protein kinase 8	0.017
Pax3	paired box gene 3	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Spna1	spectrin alpha 1	0.017
Ticam2	toll-like receptor adaptor molecule 2	0.017
Ilk	integrin linked kinase	0.017
Rrbp1	ribosome binding protein 1	0.017
Junb	Jun-B oncogene	0.016
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.016
Gna13	guanine nucleotide binding protein, alpha 13	0.016
Bmf	BCL2 modifying factor	0.016
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.016
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.016
Spn	sialophorin	0.015
6530401N04Rik	RIKEN cDNA 6530401N04 gene	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	0.015
Atxn1	ataxin 1	0.015
Akap5	A kinase (PRKA) anchor protein 5	0.015
Bach1	BTB and CNC homology 1	0.015
Ifngr2	interferon gamma receptor 2	0.015
Rpgrip1l	Rpgrip1-like	0.015
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.015
Il2rb	interleukin 2 receptor, beta chain	0.015
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.015
Vwa5a	von Willebrand factor A domain containing 5A	0.015
Alox12	arachidonate 12-lipoxygenase	0.015
Sh2b3	SH2B adaptor protein 3	0.015
Arrb2	arrestin, beta 2	0.015
Ctsl	cathepsin L	0.014
Plxnb3	plexin B3	0.014
Nmi	N-myc (and STAT) interactor	0.014
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.014
Rab27a	RAB27A, member RAS oncogene family	0.014
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.014
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.014
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.014
Mybph	myosin binding protein H	0.014
Egr2	early growth response 2	0.014
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.014
Tgfbr2	transforming growth factor, beta receptor II	0.014
Ube2c	ubiquitin-conjugating enzyme E2C	0.014
Chek2	CHK2 checkpoint homolog (S. pombe)	0.014
Necap2	NECAP endocytosis associated 2	0.014
Rbms1	RNA binding motif, single stranded interacting protein 1	0.014
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.014
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.014
Cd38	CD38 antigen	0.014
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.014
Lgals8	lectin, galactose binding, soluble 8	0.013
Mvp	major vault protein	0.013
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.013
Rictor	RPTOR independent companion of MTOR, complex 2	0.013
Sri	sorcin	0.013
Ugcg	UDP-glucose ceramide glucosyltransferase	0.013
Il27ra	interleukin 27 receptor, alpha	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Arpc1b	actin related protein 2/3 complex, subunit 1B	0.013
Sgpl1	sphingosine phosphate lyase 1	0.013
Zmynd11	zinc finger, MYND domain containing 11	0.013
Adprhl2	ADP-ribosylhydrolase like 2	0.013
Commd4	COMM domain containing 4	0.013
Nfya	nuclear transcription factor-Y alpha	0.013
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.013
Sh2d2a	SH2 domain protein 2A	0.013
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.013
Pax2	paired box gene 2	0.013
Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	0.012
Mef2a	myocyte enhancer factor 2A	0.012
Add1	adducin 1 (alpha)	0.012
Arid1b	AT rich interactive domain 1B (SWI-like)	0.012
Il13	interleukin 13	0.012
Cdk6	cyclin-dependent kinase 6	0.012
Tapbp	TAP binding protein	0.012
Bcl3	B-cell leukemia/lymphoma 3	0.012
Birc5	baculoviral IAP repeat-containing 5	0.012
Esr2	estrogen receptor 2 (beta)	0.012
Capn3	calpain 3	0.012
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.012
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.012
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.012
Phf19	PHD finger protein 19	0.012
Rbl1	retinoblastoma-like 1 (p107)	0.012
Cish	cytokine inducible SH2-containing protein	0.012
Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a	0.012	Mouse
Krtap12-1	keratin associated protein 12-1	0.012
Gbp7	guanylate binding protein 7	0.012
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.012
Ccna2	cyclin A2	0.012
Dlg1	discs, large homolog 1 (Drosophila)	0.012
Pfn1	profilin 1	0.012
Inhba	inhibin beta-A	0.012
Arhgap1	Rho GTPase activating protein 1	0.012
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.012
Cast	calpastatin	0.012
Traf2	TNF receptor-associated factor 2	0.012
Kif20a	kinesin family member 20A	0.012
Vamp4	vesicle-associated membrane protein 4	0.012
Myb	myeloblastosis oncogene	0.012
Selp	selectin, platelet	0.012
St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	0.012
Kif11	kinesin family member 11	0.012
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.012
Ehd3	EH-domain containing 3	0.012
Wrn	Werner syndrome homolog (human)	0.011
Pfn2	profilin 2	0.011
Spnb2	spectrin beta 2	0.011
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.011
Socs5	suppressor of cytokine signaling 5	0.011
Cd28	CD28 antigen	0.011
Wt1	Wilms tumor 1 homolog	0.011
Tspan14	tetraspanin 14	0.011
Abi1	abl-interactor 1	0.011
Sdc4	syndecan 4	0.011
Gm16517	predicted gene, Gm16517	0.011
Ptcd2	pentatricopeptide repeat domain 2	0.011
Pfkl	phosphofructokinase, liver, B-type	0.011
Tradd	TNFRSF1A-associated via death domain	0.011
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.011
Mllt3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	0.011
Adprhl1	ADP-ribosylhydrolase like 1	0.011
Cd44	CD44 antigen	0.011
Mtcp1	mature T-cell proliferation 1	0.011
Hr	hairless	0.011
Sycn	syncollin	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Hoxa6	homeobox A6	0.011
Il17re	interleukin 17 receptor E	0.011
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.011
Adrbk1	adrenergic receptor kinase, beta 1	0.011
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.011
Fermt3	fermitin family homolog 3 (Drosophila)	0.011
Sntb1	syntrophin, basic 1	0.011
Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	0.011
Birc7	baculoviral IAP repeat-containing 7 (livin)	0.011
Hoxc6	homeobox C6	0.011
Smad4	MAD homolog 4 (Drosophila)	0.011
Mc5r	melanocortin 5 receptor	0.011
Syce2	synaptonemal complex central element protein 2	0.010
Stard3	START domain containing 3	0.010
Emid1	EMI domain containing 1	0.010
Coq5	coenzyme Q5 homolog, methyltransferase (yeast)	0.010
Sfn	stratifin	0.010
Zyg11b	zyg-ll homolog B (C. elegans)	0.010
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.010
Qk	quaking	0.010
Aloxe3	arachidonate lipoxygenase 3	0.010
Col10a1	collagen, type X, alpha 1	0.010
Bcl10	B-cell leukemia/lymphoma 10	0.010
Rel	reticuloendotheliosis oncogene	0.010
Pax7	paired box gene 7	0.010
Pxk	PX domain containing serine/threonine kinase	0.010
Zranb1	zinc finger, RAN-binding domain containing 1	0.010
Celf2	CUGBP, Elav-like family member 2	0.010
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.010
Galnt4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4	0.010
Xcl1	chemokine (C motif) ligand 1	0.010
Casp6	caspase 6	0.010	Mouse
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.010
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.010
Epc1	enhancer of polycomb homolog 1 (Drosophila)	0.010
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.010
Irf4	interferon regulatory factor 4	0.010