IMP

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Mus musculus

17 genes annotated in mouse

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regulation of dna replication

GO:0006275

Any process that modulates the frequency, rate or extent of DNA replication.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of dna replication"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of dna replication" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Pten	phosphatase and tensin homolog	0.968
Mapk14	mitogen-activated protein kinase 14	0.964	Yeast
Ctnnb1	catenin (cadherin associated protein), beta 1	0.920
Brca1	breast cancer 1	0.662
Cdk2	cyclin-dependent kinase 2	0.549
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.528
Smc3	structural maintenace of chromosomes 3	0.522	Human
Rb1	retinoblastoma 1	0.493
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.464
Rbl1	retinoblastoma-like 1 (p107)	0.461	Fly
Smc1a	structural maintenance of chromosomes 1A	0.416	Human
Mapk8	mitogen-activated protein kinase 8	0.414	Yeast Rat
Ccne1	cyclin E1	0.408	Fly
Skil	SKI-like	0.406
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.405
Akt1	thymoma viral proto-oncogene 1	0.381
Id1	inhibitor of DNA binding 1	0.373
Hells	helicase, lymphoid specific	0.339
Ptch1	patched homolog 1	0.279
E2f1	E2F transcription factor 1	0.278
Atf2	activating transcription factor 2	0.258
Smc2	structural maintenance of chromosomes 2	0.255
Col1a1	collagen, type I, alpha 1	0.248
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.246
Shh	sonic hedgehog	0.244
Apc	adenomatosis polyposis coli	0.234
Bmp7	bone morphogenetic protein 7	0.229
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.224
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.206
H2afx	H2A histone family, member X	0.205
Atm	ataxia telangiectasia mutated homolog (human)	0.182
Mecp2	methyl CpG binding protein 2	0.165
Fgfr2	fibroblast growth factor receptor 2	0.164
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.163
Mybl2	myeloblastosis oncogene-like 2	0.154
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.151
Acd	adrenocortical dysplasia	0.150	Human
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.148
Prc1	protein regulator of cytokinesis 1	0.145
Smad3	MAD homolog 3 (Drosophila)	0.142
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.133
Csf1	colony stimulating factor 1 (macrophage)	0.122
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.119	Yeast
Ect2	ect2 oncogene	0.116
Ccne2	cyclin E2	0.114	Fly
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.108
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.104
Ccna2	cyclin A2	0.103
Top2a	topoisomerase (DNA) II alpha	0.102	Yeast
Nos3	nitric oxide synthase 3, endothelial cell	0.102
Cdk1	cyclin-dependent kinase 1	0.099	Yeast Mouse Rat
Tgfb2	transforming growth factor, beta 2	0.099
Rad21	RAD21 homolog (S. pombe)	0.098
Pthlh	parathyroid hormone-like peptide	0.096
Smc4	structural maintenance of chromosomes 4	0.090
Zeb1	zinc finger E-box binding homeobox 1	0.088
Terf1	telomeric repeat binding factor 1	0.082	Human
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.081
Timeless	timeless homolog (Drosophila)	0.081
Gab1	growth factor receptor bound protein 2-associated protein 1	0.080
Mapk9	mitogen-activated protein kinase 9	0.079	Yeast
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.078
Nbn	nibrin	0.077
Fos	FBJ osteosarcoma oncogene	0.075
Mdm2	transformed mouse 3T3 cell double minute 2	0.075
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.068
Gja1	gap junction protein, alpha 1	0.068
Raf1	v-raf-leukemia viral oncogene 1	0.066
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.064
Kit	kit oncogene	0.063
Birc5	baculoviral IAP repeat-containing 5	0.063
Tgfbr1	transforming growth factor, beta receptor I	0.062
Pax3	paired box gene 3	0.062
Gli3	GLI-Kruppel family member GLI3	0.060
Hdac1	histone deacetylase 1	0.059
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.057
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.057
Fbn1	fibrillin 1	0.057
Kif11	kinesin family member 11	0.057
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.056	Yeast
Msh2	mutS homolog 2 (E. coli)	0.056
Kitl	kit ligand	0.054	Human
Rara	retinoic acid receptor, alpha	0.054
Tcf19	transcription factor 19	0.054
Gdf5	growth differentiation factor 5	0.053	Worm
Tcf4	transcription factor 4	0.050
Meox2	mesenchyme homeobox 2	0.050
Haus6	HAUS augmin-like complex, subunit 6	0.048
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.048
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.047
Notch2	Notch gene homolog 2 (Drosophila)	0.046
Pdgfa	platelet derived growth factor, alpha	0.045	Human
Rnf220	ring finger protein 220	0.045
Ncaph	non-SMC condensin I complex, subunit H	0.044
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.044
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.044
Cenpk	centromere protein K	0.043
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.043
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.043
Mis18bp1	MIS18 binding protein 1	0.042
Sfn	stratifin	0.042
Hspa8	heat shock protein 8	0.041
Grb10	growth factor receptor bound protein 10	0.041
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.041
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.040
Prim2	DNA primase, p58 subunit	0.039
Tk1	thymidine kinase 1	0.039
Plk4	polo-like kinase 4 (Drosophila)	0.039
Rrm2	ribonucleotide reductase M2	0.038
Tsc2	tuberous sclerosis 2	0.038
Dck	deoxycytidine kinase	0.038
Fgfr1	fibroblast growth factor receptor 1	0.037
Brca2	breast cancer 2	0.036
Cyld	cylindromatosis (turban tumor syndrome)	0.036
Hcfc1	host cell factor C1	0.035
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.035
Gmnn	geminin	0.035
Kif22	kinesin family member 22	0.035
Tsc1	tuberous sclerosis 1	0.034
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.034
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.034
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.033
Pola1	polymerase (DNA directed), alpha 1	0.032
Dtl	denticleless homolog (Drosophila)	0.032
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.032
Dna2	DNA replication helicase 2 homolog (yeast)	0.031	Human
Psen1	presenilin 1	0.031
Anln	anillin, actin binding protein	0.031
Cdc7	cell division cycle 7 (S. cerevisiae)	0.031	Human
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.030
Gdf1	growth differentiation factor 1	0.029
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.029
Hsph1	heat shock 105kDa/110kDa protein 1	0.028
Prim1	DNA primase, p49 subunit	0.028
Cbl	Casitas B-lineage lymphoma	0.028
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.028
Wrn	Werner syndrome homolog (human)	0.026
Cdca8	cell division cycle associated 8	0.026
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.026
Rad51ap1	RAD51 associated protein 1	0.026
Hat1	histone aminotransferase 1	0.025
Daxx	Fas death domain-associated protein	0.025
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.025
Rbm26	RNA binding motif protein 26	0.025
Arid1a	AT rich interactive domain 1A (SWI-like)	0.025
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.025
Aip	aryl-hydrocarbon receptor-interacting protein	0.025
Grb2	growth factor receptor bound protein 2	0.024
Casp8ap2	caspase 8 associated protein 2	0.024
Lepr	leptin receptor	0.023
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.023
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.023
Haus3	HAUS augmin-like complex, subunit 3	0.023
Fgfr3	fibroblast growth factor receptor 3	0.023
Smo	smoothened homolog (Drosophila)	0.023
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.023	Human
Pkd1	polycystic kidney disease 1 homolog	0.023
Lif	leukemia inhibitory factor	0.023
Smad4	MAD homolog 4 (Drosophila)	0.022
Rad50	RAD50 homolog (S. cerevisiae)	0.022
Haus5	HAUS augmin-like complex, subunit 5	0.022
Trim59	tripartite motif-containing 59	0.022
Cdt1	chromatin licensing and DNA replication factor 1	0.022
Nanog	Nanog homeobox	0.021
Trp73	transformation related protein 73	0.021	Mouse
Lin9	lin-9 homolog (C. elegans)	0.021
Yap1	yes-associated protein 1	0.021
Cdca7	cell division cycle associated 7	0.020
Myc	myelocytomatosis oncogene	0.020
Orc1	origin recognition complex, subunit 1	0.020
Cav1	caveolin 1, caveolae protein	0.020
Hoxa13	homeobox A13	0.020
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.020
Snai2	snail homolog 2 (Drosophila)	0.019	Fly
Tmpo	thymopoietin	0.019
Ccnf	cyclin F	0.019
Tead2	TEA domain family member 2	0.019
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.019
Stag2	stromal antigen 2	0.019	Human
Atrip	ATR interacting protein	0.019
Slbp	stem-loop binding protein	0.018
Hoxa11	homeobox A11	0.018
Lama5	laminin, alpha 5	0.018
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.018
Adam17	a disintegrin and metallopeptidase domain 17	0.018
Sass6	spindle assembly 6 homolog (C. elegans)	0.017
H1	histocompatibility 1	0.017
Mtmr1	myotubularin related protein 1	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Nf1	neurofibromatosis 1	0.017
Il6st	interleukin 6 signal transducer	0.017
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.017
Mtf2	metal response element binding transcription factor 2	0.017
Hdac6	histone deacetylase 6	0.017
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.017
Ep300	E1A binding protein p300	0.016
Fen1	flap structure specific endonuclease 1	0.016
Rpgrip1l	Rpgrip1-like	0.016
Mitf	microphthalmia-associated transcription factor	0.016
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.016
Mlh1	mutL homolog 1 (E. coli)	0.016
Men1	multiple endocrine neoplasia 1	0.016	Human
Sox9	SRY-box containing gene 9	0.015
Ncapg2	non-SMC condensin II complex, subunit G2	0.015
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.015
Tfdp1	transcription factor Dp 1	0.015
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.015
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.015
Apaf1	apoptotic peptidase activating factor 1	0.015
Sp1	trans-acting transcription factor 1	0.015
Ccdc99	coiled-coil domain containing 99	0.015
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.015
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.015
Cks2	CDC28 protein kinase regulatory subunit 2	0.015
Bmp4	bone morphogenetic protein 4	0.015	Human
Xpo1	exportin 1, CRM1 homolog (yeast)	0.015
Mmp2	matrix metallopeptidase 2	0.015
Kif20a	kinesin family member 20A	0.015
Sik3	SIK family kinase 3	0.014
Zfp62	zinc finger protein 62	0.014
Cry1	cryptochrome 1 (photolyase-like)	0.014
Tfdp2	transcription factor Dp 2	0.014
Stag1	stromal antigen 1	0.014
Cdca7l	cell division cycle associated 7 like	0.014
Sin3a	transcriptional regulator, SIN3A (yeast)	0.014	Yeast
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.014
Wls	wntless homolog (Drosophila)	0.014
Kdm5b	lysine (K)-specific demethylase 5B	0.014
Otx2	orthodenticle homolog 2 (Drosophila)	0.014
Ubtd1	ubiquitin domain containing 1	0.014
S1pr2	sphingosine-1-phosphate receptor 2	0.014
Hdac2	histone deacetylase 2	0.014
Src	Rous sarcoma oncogene	0.014
Syce2	synaptonemal complex central element protein 2	0.014
Cxadr	coxsackie virus and adenovirus receptor	0.013
Raver1	ribonucleoprotein, PTB-binding 1	0.013
Ghr	growth hormone receptor	0.013
Cxcr4	chemokine (C-X-C motif) receptor 4	0.013
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.013
Fosl1	fos-like antigen 1	0.013
Ptov1	prostate tumor over expressed gene 1	0.013
Met	met proto-oncogene	0.013	Rat
Bmp2	bone morphogenetic protein 2	0.013
Igf2r	insulin-like growth factor 2 receptor	0.013
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.013	Zebrafish
Pou5f1	POU domain, class 5, transcription factor 1	0.013
Mapk11	mitogen-activated protein kinase 11	0.013	Yeast
Fubp1	far upstream element (FUSE) binding protein 1	0.013
Pygo2	pygopus 2	0.013
Lig1	ligase I, DNA, ATP-dependent	0.013
Stat5a	signal transducer and activator of transcription 5A	0.013
Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	0.013
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.013
Epha2	Eph receptor A2	0.013
Wwox	WW domain-containing oxidoreductase	0.013
Pkdcc	protein kinase domain containing, cytoplasmic	0.013
Gas1	growth arrest specific 1	0.013
Rasa1	RAS p21 protein activator 1	0.013
Fgf9	fibroblast growth factor 9	0.012
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.012	Human
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.012
Rfc2	replication factor C (activator 1) 2	0.012
Nup188	nucleoporin 188	0.012
Mapkapk2	MAP kinase-activated protein kinase 2	0.012
Usp21	ubiquitin specific peptidase 21	0.012	Yeast
Ctnnd1	catenin (cadherin associated protein), delta 1	0.012
Irs1	insulin receptor substrate 1	0.012
Ercc1	excision repair cross-complementing rodent repair deficiency, complementation group 1	0.012
Recql	RecQ protein-like	0.012
Sgpl1	sphingosine phosphate lyase 1	0.012
Wnt3a	wingless-related MMTV integration site 3A	0.012
Vrk1	vaccinia related kinase 1	0.012
D030056L22Rik	RIKEN cDNA D030056L22 gene	0.012
Ptgs2	prostaglandin-endoperoxide synthase 2	0.012
Cct4	chaperonin containing Tcp1, subunit 4 (delta)	0.012
Ncapd2	non-SMC condensin I complex, subunit D2	0.011
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.011
Arhgap1	Rho GTPase activating protein 1	0.011
Nup54	nucleoporin 54	0.011
Tcf12	transcription factor 12	0.011
Nfya	nuclear transcription factor-Y alpha	0.011
Gli2	GLI-Kruppel family member GLI2	0.011	Human
Zcchc10	zinc finger, CCHC domain containing 10	0.011
Zzz3	zinc finger, ZZ domain containing 3	0.011
Gdf6	growth differentiation factor 6	0.011	Worm
Ccnd1	cyclin D1	0.011
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.011
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.011
Arid1b	AT rich interactive domain 1B (SWI-like)	0.011
Kif23	kinesin family member 23	0.011
Atf3	activating transcription factor 3	0.011
Pola2	polymerase (DNA directed), alpha 2	0.011
Brd3	bromodomain containing 3	0.011
Ints9	integrator complex subunit 9	0.011
Usp1	ubiquitin specific peptidase 1	0.011
Per2	period homolog 2 (Drosophila)	0.010
Braf	Braf transforming gene	0.010
Shc1	src homology 2 domain-containing transforming protein C1	0.010	Rat
Racgap1	Rac GTPase-activating protein 1	0.010
Itga3	integrin alpha 3	0.010
Cdh1	cadherin 1	0.010
Lmna	lamin A	0.010
Alx1	ALX homeobox 1	0.010
Emx2	empty spiracles homolog 2 (Drosophila)	0.010
Laptm4a	lysosomal-associated protein transmembrane 4A	0.010
Mbd4	methyl-CpG binding domain protein 4	0.010
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.010
Per1	period homolog 1 (Drosophila)	0.010
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.010	Human
Etaa1	Ewing's tumor-associated antigen 1	0.010
Aurkb	aurora kinase B	0.010
Ncapd3	non-SMC condensin II complex, subunit D3	0.010
Blm	Bloom syndrome, RecQ helicase-like	0.010