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Drosophila melanogaster

29 genes annotated in fly

regulation of cell fate commitment

Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell fate commitment"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell fate commitment" (in gray)

Name	Description	Probability	Func Analog Organism
wg	wingless	0.968
gsb	gooseberry	0.937	Mouse
dpp	decapentaplegic	0.928	Human Zebrafish
dsh	dishevelled	0.849
Dll	Distal-less	0.828
Gap1	GTPase-activating protein 1	0.806
Ubx	Ultrabithorax	0.789
Doc2	Dorsocross2	0.787	Fly
slp1	sloppy paired 1	0.784
eve	even skipped	0.779
Egfr	Epidermal growth factor receptor	0.747
sli	slit	0.683
ci	cubitus interruptus	0.633
Ras85D	Ras oncogene at 85D	0.536	Worm
pnt	pointed	0.486
slou	slouch	0.467
sns	sticks and stones	0.440	Fly
trx	trithorax	0.434
lbe	ladybird early	0.413
en	engrailed	0.396
N	Notch	0.394
hth	homothorax	0.371
slmb	supernumerary limbs	0.359
nub	nubbin	0.356
sca	scabrous	0.348
prd	paired	0.347	Mouse
H	Hairless	0.345
hbs	hibris	0.344	Fly
cg	combgap	0.336
tld	tolloid	0.324
slp2	sloppy paired 2	0.324
ey	eyeless	0.315	Rat
rho	rhomboid	0.313
pdm2	POU domain protein 2	0.312
brk	brinker	0.309
Abd-B	Abdominal B	0.296
pan	pangolin	0.280	Worm
Mad	Mothers against dpp	0.277
nkd	naked cuticle	0.273
spi	spitz	0.272
run	runt	0.253
sty	sprouty	0.233
ttk	tramtrack	0.229
Tollo	CG6890 gene product from transcript CG6890-RA	0.223
insc	inscuteable	0.221
Kr	Kruppel	0.218
arm	armadillo	0.205
ftz	fushi tarazu	0.204
Lim1	CG11354 gene product from transcript CG11354-RA	0.202
tin	tinman	0.202
Poxn	Pox neuro	0.195	Fly
pb	proboscipedia	0.184
zfh1	Zn finger homeodomain 1	0.178
dac	dachshund	0.175
aop	anterior open	0.174
HGTX	CG13475 gene product from transcript CG13475-RB	0.173
hkb	huckebein	0.167
emc	extra macrochaetae	0.167
dco	discs overgrown	0.161
phl	pole hole	0.158
InR	Insulin-like receptor	0.148
disco	disconnected	0.148
fru	fruitless	0.139
ptc	patched	0.133
abd-A	abdominal A	0.128
rst	roughest	0.121	Fly
ed	echinoid	0.119
dally	division abnormally delayed	0.118
mew	multiple edematous wings	0.116
byn	brachyenteron	0.115	Fly
Antp	Antennapedia	0.114
org-1	optomotor-blind-related-gene-1	0.111	Fly
ara	araucan	0.111
bab1	bric a brac 1	0.110
rg	rugose	0.104
sob	sister of odd and bowl	0.099
SoxN	SoxNeuro	0.098
kirre	kin of irre	0.098
fkh	fork head	0.098
csw	corkscrew	0.095
C15	CG7937 gene product from transcript CG7937-RA	0.092
Imp	IGF-II mRNA-binding protein	0.087
sog	short gastrulation	0.087
mirr	mirror	0.086
mxc	multi sex combs	0.085
Mef2	Myocyte enhancer factor 2	0.083
bab2	CG9102 gene product from transcript CG9102-RA	0.080
twi	twist	0.079
B52	CG10851 gene product from transcript CG10851-RB	0.077
nab	CG33545 gene product from transcript CG33545-RC	0.075
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.074
klu	klumpfuss	0.074
rn	rotund	0.073
salm	spalt major	0.072
vnd	ventral nervous system defective	0.072
bin	biniou	0.070
Su(H)	Suppressor of Hairless	0.067	Mouse Worm
CG4168	CG4168 gene product from transcript CG4168-RA	0.066
svp	seven up	0.063
rib	ribbon	0.061	Fly
mam	mastermind	0.060
Pc	Polycomb	0.059
hh	hedgehog	0.059
Dip3	Dorsal interacting protein 3	0.059
eya	eyes absent	0.059
CG9986	CG9986 gene product from transcript CG9986-RA	0.055
ro	rough	0.054
exex	extra-extra	0.054
NELF-A	CG5874 gene product from transcript CG5874-RA	0.052
vvl	ventral veins lacking	0.051
rap	retina aberrant in pattern	0.051
al	aristaless	0.051
Hcf	Host cell factor	0.049
pum	pumilio	0.049
CG12496	CG12496 gene product from transcript CG12496-RA	0.049
lolal	lola like	0.048	Fly
pyd	polychaetoid	0.048
eyg	eyegone	0.048
sens	senseless	0.048
Ser	Serrate	0.047
CG34168	CG34168 gene product from transcript CG34168-RA	0.047
rl	rolled	0.047
argos	CG4531 gene product from transcript CG4531-RA	0.046
pyr	pyramus	0.046
CG10263	CG10263 gene product from transcript CG10263-RC	0.046
fz	frizzled	0.045
sha	shavenoid	0.044
CG4328	CG4328 gene product from transcript CG4328-RB	0.044
RpL15	Ribosomal protein L15	0.044
ham	hamlet	0.043
Snoo	Sno oncogene	0.042
tsg	twisted gastrulation	0.042
rk	rickets	0.042
S6kII	RPS6-protein kinase-II	0.041
tll	tailless	0.041
fz2	frizzled 2	0.040
par-1	CG8201 gene product from transcript CG8201-RA	0.039
CG11138	CG11138 gene product from transcript CG11138-RC	0.039
btl	breathless	0.039	Zebrafish Mouse
Doc1	Dorsocross1	0.039	Fly
sxc	super sex combs	0.038
jar	jaguar	0.038
Mrtf	Myocardin-related transcription factor	0.037
sol	small optic lobes	0.037
wb	wing blister	0.037
shg	shotgun	0.036
sno	strawberry notch	0.035
Su(var)3-7	Suppressor of variegation 3-7	0.035
CG3880	CG3880 gene product from transcript CG3880-RA	0.034
Ras64B	Ras oncogene at 64B	0.034
put	punt	0.033
Poxm	Pox meso	0.033	Fly
hpo	hippo	0.032
fas	faint sausage	0.032
Dl	Delta	0.032
CG14634	CG14634 gene product from transcript CG14634-RB	0.032
stumps	CG31317 gene product from transcript CG31317-RC	0.032
mun	munin	0.032
Kr-h1	Kruppel homolog 1	0.031
tinc	tincar	0.031
jing	CG9397 gene product from transcript CG9397-RI	0.031
klar	klarsicht	0.031
raw	CG12437 gene product from transcript CG12437-RB	0.031
Akt1	CG4006 gene product from transcript CG4006-RA	0.031
trbl	tribbles	0.030
dsf	dissatisfaction	0.030
crb	crumbs	0.030
sd	scalloped	0.030
Lim3	CG10699 gene product from transcript CG10699-RB	0.030
Dad	Daughters against dpp	0.029
gpp	grappa	0.029
hep	hemipterous	0.029
drk	downstream of receptor kinase	0.028
Actbeta	Activin-beta	0.028
drm	drumstick	0.028
Eip93F	CG18389 gene product from transcript CG18389-RB	0.028
oaf	out at first	0.027
gcm	glial cells missing	0.027
fs(1)N	female sterile (1) Nasrat	0.027
Lrt	Leucine-rich tendon-specific protein	0.026
sw	short wing	0.026
fng	fringe	0.026
Ino80	CG31212 gene product from transcript CG31212-RA	0.026
Cpr64Ad	Cuticular protein 64Ad	0.026
ths	thisbe	0.026
sev	sevenless	0.025
Pp2B-14D	Protein phosphatase 2B at 14D	0.025
kek1	kekkon-1	0.025
CG16879	CG16879 gene product from transcript CG16879-RA	0.025
alph	alphabet	0.025
Toll-6	CG7250 gene product from transcript CG7250-RA	0.024
D	Dichaete	0.024
mod(mdg4)	modifier of mdg4	0.024	Fly
edl	ETS-domain lacking	0.024
yellow-e3	CG17045 gene product from transcript CG17045-RA	0.024
cenG1A	centaurin gamma 1A	0.024
Dys	Dystrophin	0.024
dos	daughter of sevenless	0.024
CG14869	CG14869 gene product from transcript CG14869-RB	0.024
Smr	Smrter	0.024
CG15803	CG15803 gene product from transcript CG15803-RB	0.024
Gprk2	G protein-coupled receptor kinase 2	0.024
Ggamma1	G protein gamma 1	0.024
CG13921	CG13921 gene product from transcript CG13921-RB	0.023
Tao-1	CG14217 gene product from transcript CG14217-RF	0.022
wor	worniu	0.022
dib	disembodied	0.022
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.021
kni	knirps	0.021
nau	nautilus	0.021
kel	kelch	0.021
Nup153	Nucleoporin 153	0.021
Socs36E	Suppressor of cytokine signaling at 36E	0.021
lbl	ladybird late	0.021
sim	single-minded	0.021
ru	roughoid	0.020
Mob2	CG11711 gene product from transcript CG11711-RC	0.020
CTCF	CG8591 gene product from transcript CG8591-RA	0.020
tankyrase	CG4719 gene product from transcript CG4719-RA	0.020
tkv	thickveins	0.020	Mouse
Rala	Ras-related protein	0.020
Six4	CG3871 gene product from transcript CG3871-RA	0.020
Sirt7	CG11305 gene product from transcript CG11305-RA	0.019
sing	singles bar	0.019
wapl	wings apart-like	0.019
CG34449	CG34449 gene product from transcript CG34449-RB	0.019
Cpr72Ea	Cuticular protein 72Ea	0.019
CG13510	CG13510 gene product from transcript CG13510-RA	0.019
Mer	Merlin	0.019
HLH54F	CG5005 gene product from transcript CG5005-RA	0.019
mas	masquerade	0.018
CycE	Cyclin E	0.018
os	outstretched	0.018
CG3078	CG3078 gene product from transcript CG3078-RA	0.018
B-H1	BarH1	0.018
E(spl)	Enhancer of split	0.018
sinu	sinuous	0.018
Wnt4	Wnt oncogene analog 4	0.018	Fly
CG15370	CG15370 gene product from transcript CG15370-RA	0.018
CrebA	Cyclic-AMP response element binding protein A	0.018
danr	distal antenna-related	0.018
bi	bifid	0.018
bsh	brain-specific homeobox	0.018
dwg	deformed wings	0.018
lid	little imaginal discs	0.017
PHDP	Putative homeodomain protein	0.017
Ubqn	Ubiquilin	0.017
dmrt99B	doublesex-Mab related 99B	0.017
CdsA	CDP diglyceride synthetase	0.017
tna	tonalli	0.017
pnr	pannier	0.017
Toll-7	CG8595 gene product from transcript CG8595-RA	0.017
tara	taranis	0.017
B-H2	BarH2	0.016
CG34354	CG34354 gene product from transcript CG34354-RA	0.016
simj	simjang	0.016
Src64B	Src oncogene at 64B	0.016
how	held out wings	0.016
CG15646	CG15646 gene product from transcript CG15646-RA	0.016
comm	commissureless	0.016
Sox100B	CG15552 gene product from transcript CG15552-RA	0.016
AdoR	Adenosine receptor	0.016
Pk61C	Protein kinase 61C	0.016
opa	odd paired	0.016
Irk3	Inwardly rectifying potassium channel 3	0.015
luna	CG33473 gene product from transcript CG33473-RB	0.015
foxo	forkhead box, sub-group O	0.015
sala	spalt-adjacent	0.015
ato	atonal	0.014
pip	pipe	0.014
sina	seven in absentia	0.014
Tektin-A	Tektin A	0.014
CG31961	CG31961 gene product from transcript CG31961-RA	0.014
trk	trunk	0.014
toy	twin of eyeless	0.014	Rat
ec	echinus	0.014
disco-r	disco-related	0.014
NFAT	NFAT homolog	0.013
dome	domeless	0.013
dsx	doublesex	0.013
lea	leak	0.013
CG31740	CG31740 gene product from transcript CG31740-RA	0.013
CG2258	CG2258 gene product from transcript CG2258-RA	0.013
lola	longitudinals lacking	0.013	Fly
rempA	reduced mechanoreceptor potential A	0.013
l(3)05822	lethal (3) 05822	0.013
cic	capicua	0.013
CG1792	CG1792 gene product from transcript CG1792-RA	0.013
Btk29A	Btk family kinase at 29A	0.013
hbn	homeobrain	0.013
hipk	homeodomain interacting protein kinase	0.013
MYPT-75D	CG6896 gene product from transcript CG6896-RA	0.013
calypso	CG8445 gene product from transcript CG8445-RB	0.013
Dsp1	Dorsal switch protein 1	0.013
bnl	branchless	0.013
dy	dusky	0.013
beat-Ia	beaten path Ia	0.013
Hr38	Hormone receptor-like in 38	0.013
stwl	stonewall	0.013
Notum	CG13076 gene product from transcript CG13076-RB	0.013
gro	groucho	0.013
CG11696	CG11696 gene product from transcript CG11696-RA	0.013
dnt	doughnut on 2	0.012
CG5694	CG5694 gene product from transcript CG5694-RA	0.012
wdb	widerborst	0.012
pzg	putzig	0.012
CG11593	CG11593 gene product from transcript CG11593-RB	0.012
CG32666	CG32666 gene product from transcript CG32666-RC	0.012
cv-2	crossveinless 2	0.012
net	CG11450 gene product from transcript CG11450-RB	0.012
CG8290	CG8290 gene product from transcript CG8290-RA	0.012
CG7039	CG7039 gene product from transcript CG7039-RA	0.012
CG12344	CG12344 gene product from transcript CG12344-RA	0.012
spdo	sanpodo	0.012
rin	rasputin	0.012
apt	apontic	0.012
sut1	sugar transporter 1	0.012
Sas	Sialic acid phosphate synthase	0.012
Rac2	CG8556 gene product from transcript CG8556-RA	0.012
CG11275	CG11275 gene product from transcript CG11275-RA	0.011
RhoGAP19D	CG1412 gene product from transcript CG1412-RB	0.011
nmo	nemo	0.011
Traf4	TNF-receptor-associated factor 4	0.011
CG12054	CG12054 gene product from transcript CG12054-RA	0.011
dm	diminutive	0.011
CG16813	CG16813 gene product from transcript CG16813-RA	0.011
CG4542	CG4542 gene product from transcript CG4542-RA	0.011
ex	expanded	0.011
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.011
ase	asense	0.011
CtBP	C-terminal Binding Protein	0.011
fd59A	forkhead domain 59A	0.011
Lk6	CG17342 gene product from transcript CG17342-RA	0.011
amos	absent MD neurons and olfactory sensilla	0.011
CG30158	CG30158 gene product from transcript CG30158-RA	0.011
lqfR	liquid facets-Related	0.011
caz	cabeza	0.011
CG14667	CG14667 gene product from transcript CG14667-RA	0.011
CG13333	CG13333 gene product from transcript CG13333-RA	0.011
CG14193	CG14193 gene product from transcript CG14193-RA	0.011
upd2	unpaired 2	0.011
nimC3	nimrod C3	0.010
CG17377	CG17377 gene product from transcript CG17377-RA	0.010
Arf51F	ADP ribosylation factor 51F	0.010
CG32532	CG32532 gene product from transcript CG32532-RA	0.010
Tom	Twin of m4	0.010
Tehao	CG7121 gene product from transcript CG7121-RA	0.010
Hr46	Hormone receptor-like in 46	0.010
Lsd-2	Lipid storage droplet-2	0.010
CG6592	CG6592 gene product from transcript CG6592-RA	0.010
wkd	whacked	0.010
sna	snail	0.010
CG10209	CG10209 gene product from transcript CG10209-RA	0.010
odd	odd skipped	0.010
CG6425	CG6425 gene product from transcript CG6425-RA	0.010
CG15479	CG15479 gene product from transcript CG15479-RA	0.010
CG3726	CG3726 gene product from transcript CG3726-RA	0.010
Sox21b	CG32139 gene product from transcript CG32139-RA	0.010
tey	teyrha-meyrha	0.010