IMP

Process View

Mus musculus

26 genes annotated in mouse

Multi-species View

transcription factor import into nucleus

GO:0042991

The directed movement of a transcription factor from the cytoplasm to the nucleus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "transcription factor import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "transcription factor import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.930
Ctnnb1	catenin (cadherin associated protein), beta 1	0.859
Il1r1	interleukin 1 receptor, type I	0.671	Mouse
Apc	adenomatosis polyposis coli	0.489
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.300
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.298
Lta	lymphotoxin A	0.297	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.238
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.224
Trp63	transformation related protein 63	0.217	Fly
Edaradd	EDAR (ectodysplasin-A receptor)-associated death domain	0.211
Il6st	interleukin 6 signal transducer	0.206
Fgfr1	fibroblast growth factor receptor 1	0.200
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.198
Pten	phosphatase and tensin homolog	0.173	Worm
Gli3	GLI-Kruppel family member GLI3	0.171
Ar	androgen receptor	0.156
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.145
Casp1	caspase 1	0.140
Il6	interleukin 6	0.135
Rara	retinoic acid receptor, alpha	0.134	Mouse
Lyz2	lysozyme 2	0.126
Cd40	CD40 antigen	0.124
Fas	Fas (TNF receptor superfamily member 6)	0.121
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.114
Trp53	transformation related protein 53	0.110	Fly
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.108
Rarg	retinoic acid receptor, gamma	0.107	Mouse
Mapkap1	mitogen-activated protein kinase associated protein 1	0.103
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.099
Htt	huntingtin	0.098
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.092
Tgfb2	transforming growth factor, beta 2	0.091
Rxra	retinoid X receptor alpha	0.086
Psen1	presenilin 1	0.085
Lrp6	low density lipoprotein receptor-related protein 6	0.081
Ncoa3	nuclear receptor coactivator 3	0.080
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.075
Cd44	CD44 antigen	0.075
Pkd1	polycystic kidney disease 1 homolog	0.074
Il7	interleukin 7	0.071
Cxcr5	chemokine (C-X-C motif) receptor 5	0.070
Dbp	D site albumin promoter binding protein	0.067
Ikbkg	inhibitor of kappaB kinase gamma	0.063
Per1	period homolog 1 (Drosophila)	0.062
Bmp4	bone morphogenetic protein 4	0.059
Grb10	growth factor receptor bound protein 10	0.056
Lepr	leptin receptor	0.055
Smo	smoothened homolog (Drosophila)	0.054
Il10	interleukin 10	0.053
Axin1	axin 1	0.052
Emx1	empty spiracles homolog 1 (Drosophila)	0.051
Cand1	cullin associated and neddylation disassociated 1	0.051
Sox9	SRY-box containing gene 9	0.049
Eya1	eyes absent 1 homolog (Drosophila)	0.049
Vdr	vitamin D receptor	0.048
Myd88	myeloid differentiation primary response gene 88	0.048
Hs1bp3	HCLS1 binding protein 3	0.046
Smad3	MAD homolog 3 (Drosophila)	0.045	Human
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.044
Il1b	interleukin 1 beta	0.044	Human
Stim2	stromal interaction molecule 2	0.044	Fly
Fam96a	family with sequence similarity 96, member A	0.043
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.042
Ccl2	chemokine (C-C motif) ligand 2	0.041
Ccr1	chemokine (C-C motif) receptor 1	0.041
Rel	reticuloendotheliosis oncogene	0.041
Gli2	GLI-Kruppel family member GLI2	0.041
Cd28	CD28 antigen	0.041
Il1r2	interleukin 1 receptor, type II	0.040	Mouse
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.040	Mouse Fly
Rptor	regulatory associated protein of MTOR, complex 1	0.039
Tlr4	toll-like receptor 4	0.039	Human
Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	0.038
Cux1	cut-like homeobox 1	0.038
Kif20a	kinesin family member 20A	0.037
Yap1	yes-associated protein 1	0.037
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.037
Nodal	nodal	0.037
Anapc2	anaphase promoting complex subunit 2	0.037
Ptch1	patched homolog 1	0.036
Notch2	Notch gene homolog 2 (Drosophila)	0.035
Bcl6	B-cell leukemia/lymphoma 6	0.035
Zeb1	zinc finger E-box binding homeobox 1	0.034
Rnf115	ring finger protein 115	0.034
Gspt1	G1 to S phase transition 1	0.034
Il18rap	interleukin 18 receptor accessory protein	0.034	Mouse
Smad2	MAD homolog 2 (Drosophila)	0.034
Traf3	TNF receptor-associated factor 3	0.034
Ltb	lymphotoxin B	0.033
Bcl2	B-cell leukemia/lymphoma 2	0.033
Slc12a6	solute carrier family 12, member 6	0.032
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.032
Ikzf1	IKAROS family zinc finger 1	0.032
Lhx1	LIM homeobox protein 1	0.032
Pom121	nuclear pore membrane protein 121	0.031
Il1a	interleukin 1 alpha	0.031
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.031
Kpna1	karyopherin (importin) alpha 1	0.031
Tox	thymocyte selection-associated high mobility group box	0.031
Pax8	paired box gene 8	0.030
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.030
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.030
Ptgs2	prostaglandin-endoperoxide synthase 2	0.030	Rat
Cys1	cystin 1	0.029
Hoxd11	homeobox D11	0.029
Ticam1	toll-like receptor adaptor molecule 1	0.028
Traf1	TNF receptor-associated factor 1	0.028
Ilk	integrin linked kinase	0.028
Pbx1	pre B-cell leukemia transcription factor 1	0.028
Clec4d	C-type lectin domain family 4, member d	0.027
Nos2	nitric oxide synthase 2, inducible	0.027
Socs1	suppressor of cytokine signaling 1	0.027
Igbp1	immunoglobulin (CD79A) binding protein 1	0.026
Eya2	eyes absent 2 homolog (Drosophila)	0.026
Il2rb	interleukin 2 receptor, beta chain	0.026
Nlrp3	NLR family, pyrin domain containing 3	0.026	Human
Pou2af1	POU domain, class 2, associating factor 1	0.026
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.026
Stim1	stromal interaction molecule 1	0.026	Fly
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.026
Igf1r	insulin-like growth factor I receptor	0.025	Worm
Clec4e	C-type lectin domain family 4, member e	0.025
Il1rl1	interleukin 1 receptor-like 1	0.025	Mouse
Nf2	neurofibromatosis 2	0.024
Sh3gl1	SH3-domain GRB2-like 1	0.024
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.024
Telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.023
Pparg	peroxisome proliferator activated receptor gamma	0.023
Gjb2	gap junction protein, beta 2	0.023
Meox2	mesenchyme homeobox 2	0.023
Stat6	signal transducer and activator of transcription 6	0.022
Rpgrip1l	Rpgrip1-like	0.022
Cdh23	cadherin 23 (otocadherin)	0.022
Pdlim4	PDZ and LIM domain 4	0.022
Mmp8	matrix metallopeptidase 8	0.022
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.022
Socs3	suppressor of cytokine signaling 3	0.022
Anln	anillin, actin binding protein	0.022
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.022
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.021	Human
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.021
Esr2	estrogen receptor 2 (beta)	0.021
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.021
Stat3	signal transducer and activator of transcription 3	0.020
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.020
Itk	IL2-inducible T-cell kinase	0.020
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.020
Cul3	cullin 3	0.020
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.020
Gna11	guanine nucleotide binding protein, alpha 11	0.020
Bcap31	B-cell receptor-associated protein 31	0.020
Ikbkb	inhibitor of kappaB kinase beta	0.020
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.020
Sell	selectin, lymphocyte	0.019
Bmper	BMP-binding endothelial regulator	0.019
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.019
Mtap1s	microtubule-associated protein 1S	0.019
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.019
Slfn4	schlafen 4	0.019
Cep55	centrosomal protein 55	0.019
Rarb	retinoic acid receptor, beta	0.019	Mouse
Rnf31	ring finger protein 31	0.018
Sap18	Sin3-associated polypeptide 18	0.018
Bicc1	bicaudal C homolog 1 (Drosophila)	0.018
Smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.018
Cxcl2	chemokine (C-X-C motif) ligand 2	0.018
Adam8	a disintegrin and metallopeptidase domain 8	0.018
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.018
Lck	lymphocyte protein tyrosine kinase	0.018
Hbb-b1	hemoglobin, beta adult major chain	0.018
Ppp2r5d	protein phosphatase 2, regulatory subunit B (B56), delta isoform	0.018
Bmp7	bone morphogenetic protein 7	0.018
Fgf9	fibroblast growth factor 9	0.017
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.017
Il33	interleukin 33	0.017
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.017
Tbx3	T-box 3	0.017
Rora	RAR-related orphan receptor alpha	0.017
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.017
Cxcl1	chemokine (C-X-C motif) ligand 1	0.017
Ipo5	importin 5	0.017
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.017
Cyld	cylindromatosis (turban tumor syndrome)	0.016	Human
Il1rap	interleukin 1 receptor accessory protein	0.016	Mouse
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.016
Hhat	hedgehog acyltransferase	0.016
Il4	interleukin 4	0.016
Osmr	oncostatin M receptor	0.016
Shh	sonic hedgehog	0.015	Fly
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.015
App	amyloid beta (A4) precursor protein	0.015
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.015
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.015
Ccl4	chemokine (C-C motif) ligand 4	0.015
Mks1	Meckel syndrome, type 1	0.015
Ppap2b	phosphatidic acid phosphatase type 2B	0.015
Kcna7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.015
Cbl	Casitas B-lineage lymphoma	0.015
Lrrk2	leucine-rich repeat kinase 2	0.015
Topbp1	topoisomerase (DNA) II binding protein 1	0.015
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.015
Arl8b	ADP-ribosylation factor-like 8B	0.015
Tmpo	thymopoietin	0.015
Sox4	SRY-box containing gene 4	0.015
Top2a	topoisomerase (DNA) II alpha	0.015
Ppif	peptidylprolyl isomerase F (cyclophilin F)	0.015
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.015
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.015	Mouse
Ptk2	PTK2 protein tyrosine kinase 2	0.014
Racgap1	Rac GTPase-activating protein 1	0.014
Csf1	colony stimulating factor 1 (macrophage)	0.014
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.014	Human
Lef1	lymphoid enhancer binding factor 1	0.014
Ckap2	cytoskeleton associated protein 2	0.014
Itgb4	integrin beta 4	0.014
Pnp	purine-nucleoside phosphorylase	0.014
Kif22	kinesin family member 22	0.014
Sf3b3	splicing factor 3b, subunit 3	0.014
Dazap2	DAZ associated protein 2	0.014
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.014
Rnh1	ribonuclease/angiogenin inhibitor 1	0.014
Ep300	E1A binding protein p300	0.014
Fgfrl1	fibroblast growth factor receptor-like 1	0.014
Mmp9	matrix metallopeptidase 9	0.014
Spp1	secreted phosphoprotein 1	0.013
Megf8	multiple EGF-like-domains 8	0.013
Gab1	growth factor receptor bound protein 2-associated protein 1	0.013
Pitx2	paired-like homeodomain transcription factor 2	0.013
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.013
Mecp2	methyl CpG binding protein 2	0.013
Cd86	CD86 antigen	0.013
Per2	period homolog 2 (Drosophila)	0.013
Irf6	interferon regulatory factor 6	0.013
Hsf1	heat shock factor 1	0.013
Ate1	arginyltransferase 1	0.013
Fgfr3	fibroblast growth factor receptor 3	0.013
Gsk3b	glycogen synthase kinase 3 beta	0.013	Human
Irg1	immunoresponsive gene 1	0.013
Prdm16	PR domain containing 16	0.013
Caprin1	cell cycle associated protein 1	0.013
Zfp574	zinc finger protein 574	0.013
Birc3	baculoviral IAP repeat-containing 3	0.013
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.013
Ncaph	non-SMC condensin I complex, subunit H	0.013
Casp3	caspase 3	0.013
Ptpn23	protein tyrosine phosphatase, non-receptor type 23	0.013
Il22	interleukin 22	0.013
Has1	hyaluronan synthase1	0.013
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.013
Rictor	RPTOR independent companion of MTOR, complex 2	0.013
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.013
Crtap	cartilage associated protein	0.013
Lif	leukemia inhibitory factor	0.013
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.013	Mouse
Tlr6	toll-like receptor 6	0.013
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.013
Vhl	von Hippel-Lindau tumor suppressor	0.013
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Kif11	kinesin family member 11	0.013
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.013
Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)	0.013
Tmem115	transmembrane protein 115	0.013
Emx2	empty spiracles homolog 2 (Drosophila)	0.013
Il2	interleukin 2	0.012
Sept9	septin 9	0.012
Igh	immunoglobulin heavy chain complex	0.012
Icos	inducible T-cell co-stimulator	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.012
Gzma	granzyme A	0.012
Adss	adenylosuccinate synthetase, non muscle	0.012
Fuz	fuzzy homolog (Drosophila)	0.012
Kif4	kinesin family member 4	0.012
Numb	numb gene homolog (Drosophila)	0.012
Gba	glucosidase, beta, acid	0.012
Timm22	translocase of inner mitochondrial membrane 22 homolog (yeast)	0.012
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.012
Rab10	RAB10, member RAS oncogene family	0.012
Nckap1	NCK-associated protein 1	0.012
Wnt3a	wingless-related MMTV integration site 3A	0.012
Traf2	TNF receptor-associated factor 2	0.012
Cxcl13	chemokine (C-X-C motif) ligand 13	0.012
Sfn	stratifin	0.012
Snapc2	small nuclear RNA activating complex, polypeptide 2	0.012
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.012
Ctsl	cathepsin L	0.012
Acvr1	activin A receptor, type 1	0.012
Lcp2	lymphocyte cytosolic protein 2	0.012
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.012
Commd6	COMM domain containing 6	0.012
Esd	esterase D/formylglutathione hydrolase	0.012
Pycard	PYD and CARD domain containing	0.012
Lrp4	low density lipoprotein receptor-related protein 4	0.012
Lrp5	low density lipoprotein receptor-related protein 5	0.012
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.012
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.012
Nfix	nuclear factor I/X	0.012
Cd3e	CD3 antigen, epsilon polypeptide	0.012
H2-Q5	histocompatibility 2, Q region locus 5	0.012
Tsen34	tRNA splicing endonuclease 34 homolog (S. cerevisiae)	0.012
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.011
Slpi	secretory leukocyte peptidase inhibitor	0.011
Kif2c	kinesin family member 2C	0.011
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.011
Cav1	caveolin 1, caveolae protein	0.011
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.011
Plaur	plasminogen activator, urokinase receptor	0.011
Chmp2a	chromatin modifying protein 2A	0.011
Card11	caspase recruitment domain family, member 11	0.011
Tef	thyrotroph embryonic factor	0.011
Sik3	SIK family kinase 3	0.011
Rdh10	retinol dehydrogenase 10 (all-trans)	0.011
Rxrb	retinoid X receptor beta	0.011
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.011
Skil	SKI-like	0.011
Fasl	Fas ligand (TNF superfamily, member 6)	0.011	Mouse
Ghitm	growth hormone inducible transmembrane protein	0.011
Rab6	RAB6, member RAS oncogene family	0.011
Hr	hairless	0.011
Foxb2	forkhead box B2	0.011
Wdr45l	Wdr45 like	0.011
Cd80	CD80 antigen	0.011
Pros1	protein S (alpha)	0.011
Mcl1	myeloid cell leukemia sequence 1	0.011
Setdb1	SET domain, bifurcated 1	0.011
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.011
Il11	interleukin 11	0.011
Sox2	SRY-box containing gene 2	0.011
Tuba1a	tubulin, alpha 1A	0.011
Ddb1	damage specific DNA binding protein 1	0.011
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.011
Hdac1	histone deacetylase 1	0.011
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.011
Rhbdf1	rhomboid family 1 (Drosophila)	0.011
Ebi3	Epstein-Barr virus induced gene 3	0.011
Tjp1	tight junction protein 1	0.011
Casp8	caspase 8	0.011
Coro1b	coronin, actin binding protein 1B	0.011
Elane	elastase, neutrophil expressed	0.011
Pdcd6	programmed cell death 6	0.011	Mouse
Ccl17	chemokine (C-C motif) ligand 17	0.011
Mapk1	mitogen-activated protein kinase 1	0.011
Hrh2	histamine receptor H2	0.011
Cd96	CD96 antigen	0.011
Nog	noggin	0.011
Kif1b	kinesin family member 1B	0.011
Tsc2	tuberous sclerosis 2	0.011
Xpo6	exportin 6	0.011
Hdac6	histone deacetylase 6	0.011
Pnp2	purine-nucleoside phosphorylase 2	0.011
Mprip	myosin phosphatase Rho interacting protein	0.010
Fpr2	formyl peptide receptor 2	0.010
Xcl1	chemokine (C motif) ligand 1	0.010
Hoxa5	homeobox A5	0.010
Usp21	ubiquitin specific peptidase 21	0.010
Ift140	intraflagellar transport 140 homolog (Chlamydomonas)	0.010
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.010
Qk	quaking	0.010
Shoc2	soc-2 (suppressor of clear) homolog (C. elegans)	0.010
Cd81	CD81 antigen	0.010
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.010
Snx13	sorting nexin 13	0.010
Sphk1	sphingosine kinase 1	0.010	Human
Huwe1	HECT, UBA and WWE domain containing 1	0.010
Gm3150	predicted gene 3150	0.010
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.010
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.010
Glod4	glyoxalase domain containing 4	0.010
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.010
Smad5	MAD homolog 5 (Drosophila)	0.010
Brca2	breast cancer 2	0.010
Itgb2	integrin beta 2	0.010
Gabarap	gamma-aminobutyric acid receptor associated protein	0.010
Sra1	steroid receptor RNA activator 1	0.010