IMP

Process View

Drosophila melanogaster

28 genes annotated in fly

exocytosis

A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "exocytosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "exocytosis" (in gray)

Name	Description	Probability	Func Analog Organism
Rab5	Rab-protein 5	0.986	Human
Rab11	Rab-protein 11	0.784	Human Yeast Rat Worm
wit	wishful thinking	0.767
rhea	CG6831 gene product from transcript CG6831-RA	0.678
egl	egalitarian	0.651
cpa	capping protein alpha	0.530
Actbeta	Activin-beta	0.509
Snap25	Synapse protein 25	0.479
CkIIalpha	Casein kinase II alpha subunit	0.444
Chc	Clathrin heavy chain	0.409
unc-104	CG8566 gene product from transcript CG8566-RB	0.406	Worm
par-1	CG8201 gene product from transcript CG8201-RA	0.397
Syx1A	Syntaxin 1A	0.322
Syt4	Synaptotagmin 4	0.318
GluRIIA	Glutamate receptor IIA	0.306
Rac1	CG2248 gene product from transcript CG2248-RA	0.298
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.272
comt	comatose	0.267
scb	scab	0.260
Arp66B	Actin-related protein 66B	0.242
ewg	erect wing	0.226
baz	bazooka	0.218
shn	schnurri	0.215
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.201
faf	fat facets	0.199
CG10566	CG10566 gene product from transcript CG10566-RA	0.198
Nsf2	NEM-sensitive fusion protein 2	0.196	Rat Fly
wun	wunen	0.179
Smg1	CG32743 gene product from transcript CG32743-RA	0.179
Khc-73	Kinesin-73	0.178
brp	bruchpilot	0.154
arm	armadillo	0.154
hiw	highwire	0.127
CG8552	CG8552 gene product from transcript CG8552-RA	0.127
Pde8	Phosphodiesterase 8	0.126
endoA	endophilin A	0.122
Rab6	Rab-protein 6	0.119
jar	jaguar	0.107
Atpalpha	Na pump alpha subunit	0.105
Frq2	Frequenin 2	0.101	Rat
Khc	Kinesin heavy chain	0.099
wdb	widerborst	0.099
Rep	Rab escort protein	0.098
Dlic	Dynein light intermediate chain	0.094
Lrrk	Leucine-rich repeat kinase	0.093	Human
Eip63F-1	Ecdysone-induced protein 63F 1	0.092
Rop	Ras opposite	0.090	Mouse Rat Worm
Ank2	Ankyrin 2	0.090
Fps85D	Fps oncogene analog	0.088	Human
Caki	Calcium/calmodulin-dependent protein kinase	0.084
onecut	CG1922 gene product from transcript CG1922-RA	0.080
Nrx-1	Neurexin 1	0.074
Imp	IGF-II mRNA-binding protein	0.072
rl	rolled	0.071
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.070
Syx13	Syntaxin 13	0.068
CG33129	CG33129 gene product from transcript CG33129-RE	0.067
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.065	Human
klar	klarsicht	0.063
Dab	Disabled	0.061
AdoR	Adenosine receptor	0.060
Cip4	CG15015 gene product from transcript CG15015-RA	0.060
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.060
CG31531	CG31531 gene product from transcript CG31531-RC	0.060
Pp2B-14D	Protein phosphatase 2B at 14D	0.059	Mouse
cert	ceramide transfer protein	0.058
CG6191	CG6191 gene product from transcript CG6191-RA	0.058
Rab3	Rab-protein 3	0.057	Human Mouse
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.055
Dad	Daughters against dpp	0.055
Shaw	Shaker cognate w	0.054
Frq1	Frequenin 1	0.054	Rat
rtGEF	rho-type guanine exchange factor	0.053
lap	like-AP180	0.052
p130CAS	CG1212 gene product from transcript CG1212-RA	0.052
stj	straightjacket	0.052
Tak1	TGF-beta activated kinase 1	0.051
Tre1	trapped in endoderm-1	0.051
neuroligin	CG13772 gene product from transcript CG13772-RA	0.049	Mouse Rat
sina	seven in absentia	0.047
sei	seizure	0.046
CG11210	CG11210 gene product from transcript CG11210-RA	0.044
Vmat	Vesicular monoamine transporter	0.044
Nrg	Neuroglian	0.043
CG14782	CG14782 gene product from transcript CG14782-RA	0.043
Shab	Shaker cognate b	0.042
beta-Spec	beta Spectrin	0.042
unc-13	CG2999 gene product from transcript CG2999-RA	0.042
Mob4	CG3403 gene product from transcript CG3403-RA	0.042
dnc	dunce	0.041
cnk	connector enhancer of ksr	0.041
mtg	mind the gap	0.040
stnA	stoned A	0.040
slo	slowpoke	0.039
Sdc	Syndecan	0.038
synj	synaptojanin	0.038	Mouse
nAcRalpha-30D	nicotinic Acetylcholine Receptor alpha 30D	0.037
CG18259	CG18259 gene product from transcript CG18259-RA	0.036
shot	short stop	0.036
sqh	spaghetti squash	0.035
Syb	Synaptobrevin	0.033	Worm
msn	misshapen	0.033
CG12007	CG12007 gene product from transcript CG12007-RA	0.033
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.032
CSN4	COP9 complex homolog subunit 4	0.032
Sec22	CG7359 gene product from transcript CG7359-RA	0.031
Syt1	Synaptotagmin 1	0.031	Mouse Rat
RhoGAP15B	CG4937 gene product from transcript CG4937-RC	0.031
Jra	Jun-related antigen	0.031
CG12187	CG12187 gene product from transcript CG12187-RA	0.031
Snap	Soluble NSF attachment protein	0.031
CG2950	CG2950 gene product from transcript CG2950-RD	0.030
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.030
shrb	shrub	0.030
Pi3K68D	Phosphotidylinositol 3 kinase 68D	0.030
Dat	Dopamine N acetyltransferase	0.030
rev7	CG2948 gene product from transcript CG2948-RA	0.030
HDAC6	CG6170 gene product from transcript CG6170-RA	0.030
Oamb	Octopamine receptor in mushroom bodies	0.030
Rho1	CG8416 gene product from transcript CG8416-RB	0.029
Lis-1	Lissencephaly-1	0.029
tomosyn	CG17762 gene product from transcript CG17762-RB	0.029	Mouse
mbc	myoblast city	0.029
gammaSnap	gamma-soluble NSF attachment protein	0.029
cac	cacophony	0.028
5-HT1B	Serotonin receptor 1B	0.028
Nop60B	Nucleolar protein at 60B	0.028
rho-5	rhomboid-5	0.028
gho	ghost	0.028
Ipp	Inositol polyphosphate 1-phosphatase	0.028
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.026
Rab35	CG9575 gene product from transcript CG9575-RA	0.026
par-6	CG5884 gene product from transcript CG5884-RA	0.026
CG12012	CG12012 gene product from transcript CG12012-RA	0.026
Gmd	GDP-mannose 4,6-dehydratase	0.025
VGlut	Vesicular glutamate transporter	0.025
CG32810	CG32810 gene product from transcript CG32810-RB	0.025
raps	rapsynoid	0.025
Act5C	Actin 5C	0.025
CG3563	CG3563 gene product from transcript CG3563-RA	0.024
AGO1	Argonaute-1	0.024
Pak3	CG14895 gene product from transcript CG14895-RA	0.024
HLH4C	Helix loop helix protein 4C	0.024
lva	lava lamp	0.024
Drep-4	DNA fragmentation factor-related protein 4	0.024
dia	diaphanous	0.024
spen	split ends	0.024
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.024
betaInt-nu	beta[nu] integrin	0.023
mask	multiple ankyrin repeats single KH domain	0.023
CG11317	CG11317 gene product from transcript CG11317-RA	0.023
aop	anterior open	0.023
cno	canoe	0.023
mew	multiple edematous wings	0.023
tweek	CG42555 gene product from transcript CG42555-RD	0.022
CanA1	Calcineurin A1	0.022	Mouse
syd	sunday driver	0.022
lace	CG4162 gene product from transcript CG4162-RA	0.022
EndoGI	Endonuclease G inhibitor	0.022
Mad	Mothers against dpp	0.022
CG1233	CG1233 gene product from transcript CG1233-RB	0.022
CdsA	CDP diglyceride synthetase	0.022
ics	icarus	0.022
dys	dysfusion	0.021
deltaCOP	delta-coatomer protein	0.021
Pk61C	Protein kinase 61C	0.021	Mouse
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.021
trio	CG18214 gene product from transcript CG18214-RA	0.021
CG32635	CG32635 gene product from transcript CG32635-RA	0.021
spin	spinster	0.021
Kap-alpha3	karyopherin alpha3	0.021
CG2938	CG2938 gene product from transcript CG2938-RB	0.020
skf	skiff	0.020
CG9053	CG9053 gene product from transcript CG9053-RA	0.020
sfl	sulfateless	0.020
Ctr1A	Copper transporter 1A	0.020
CG12945	CG12945 gene product from transcript CG12945-RB	0.020
beta4GalNAcTA	CG8536 gene product from transcript CG8536-RA	0.020
CG10508	CG10508 gene product from transcript CG10508-RH	0.020
CalpB	Calpain-B	0.020
Alk	CG8250 gene product from transcript CG8250-RA	0.020
Syx18	Syntaxin 18	0.020
mfrn	mitoferrin	0.019
CG12001	CG12001 gene product from transcript CG12001-RA	0.019
CG6854	CG6854 gene product from transcript CG6854-RC	0.019
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.019
p115	CG1422 gene product from transcript CG1422-RA	0.019
Moe	Moesin	0.019
poe	purity of essence	0.019
Wnk	CG7177 gene product from transcript CG7177-RA	0.019
CanB	Calcineurin B	0.019
Sop2	Suppressor of profilin 2	0.019
drk	downstream of receptor kinase	0.019
Stam	Signal transducing adaptor molecule	0.019	Human
M6	CG7540 gene product from transcript CG7540-RA	0.018
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.018
cdi	center divider	0.018
CG7967	CG7967 gene product from transcript CG7967-RA	0.018
Scp2	Sarcoplasmic calcium-binding protein 2	0.018
Syx7	Syntaxin 7	0.018
Mgat2	CG7921 gene product from transcript CG7921-RA	0.018
hk	hook	0.018
alph	alphabet	0.018
mle	maleless	0.018
fne	found in neurons	0.018
Syx8	Syntaxin 8	0.018
bowl	brother of odd with entrails limited	0.018
tim	timeless	0.018
Myo61F	Myosin 61F	0.017
hth	homothorax	0.017
NtR	CG6698 gene product from transcript CG6698-RA	0.017
CG8443	CG8443 gene product from transcript CG8443-RA	0.017
B52	CG10851 gene product from transcript CG10851-RB	0.017
Rbp9	RNA-binding protein 9	0.017
CG5036	CG5036 gene product from transcript CG5036-RB	0.017
n-syb	n-synaptobrevin	0.017
nAcRalpha-80B	nicotinic Acetylcholine Receptor alpha 80B	0.017
Xe7	CG2179 gene product from transcript CG2179-RA	0.017
Lerp	lysosomal enzyme receptor protein	0.017
hep	hemipterous	0.017
Pp2A-29B	Protein phosphatase 2A at 29B	0.017
CG5466	CG5466 gene product from transcript CG5466-RA	0.017
Ykt6	CG1515 gene product from transcript CG1515-RA	0.017
Gie	novel GTPase indispensable for equal segregation of chromosomes	0.017
dally	division abnormally delayed	0.016
spict	spichthyin	0.016
htt	huntingtin	0.016
CG10830	CG10830 gene product from transcript CG10830-RA	0.016
wnd	wallenda	0.016
CHMP2B	Charged multivesicular body protein 2b	0.016
CG17019	CG17019 gene product from transcript CG17019-RA	0.016
CG6259	CG6259 gene product from transcript CG6259-RA	0.016
Pink1	PTEN-induced putative kinase 1	0.016
Gyc76C	Guanylyl cyclase at 76C	0.016
CG31191	CG31191 gene product from transcript CG31191-RA	0.016
synaptogyrin	CG10808 gene product from transcript CG10808-RA	0.016
dlg1	discs large 1	0.016
nej	nejire	0.015
Psn	Presenilin	0.015	Mouse
Syn2	Syntrophin-like 2	0.015
sgg	shaggy	0.015
mr	morula	0.015
CG6424	CG6424 gene product from transcript CG6424-RA	0.015
CG7158	CG7158 gene product from transcript CG7158-RA	0.015
lsn	larsen	0.015
sif	still life	0.015
Krn	Keren	0.015
HERC2	CG11734 gene product from transcript CG11734-RC	0.015
Lim3	CG10699 gene product from transcript CG10699-RB	0.015
Mpk2	CG5475 gene product from transcript CG5475-RB	0.015
Syx5	Syntaxin 5	0.015
per	period	0.015
Tbh	Tyramine beta hydroxylase	0.015
CG11284	CG11284 gene product from transcript CG11284-RA	0.015
CG4617	CG4617 gene product from transcript CG4617-RA	0.015
CG8500	CG8500 gene product from transcript CG8500-RA	0.015
CG17508	CG17508 gene product from transcript CG17508-RA	0.015
CG17265	CG17265 gene product from transcript CG17265-RA	0.015
PHDP	Putative homeodomain protein	0.014
atl	atlastin	0.014
c11.1	CG12132 gene product from transcript CG12132-RA	0.014
Sac1	CG9128 gene product from transcript CG9128-RB	0.014
Su(dx)	Suppressor of deltex	0.014
krz	kurtz	0.014
CG13409	CG13409 gene product from transcript CG13409-RA	0.014
CG4194	CG4194 gene product from transcript CG4194-RA	0.014
VAChT	CG32848 gene product from transcript CG32848-RA	0.014
didum	dilute class unconventional myosin	0.014
cv-c	crossveinless c	0.014
CG16791	CG16791 gene product from transcript CG16791-RA	0.014
mthl4	methuselah-like 4	0.014	Fly
Rac2	CG8556 gene product from transcript CG8556-RA	0.014
CG10778	CG10778 gene product from transcript CG10778-RA	0.014
garz	gartenzwerg	0.014
HisCl1	Histamine-gated chloride channel subunit 1	0.013
Oli	Olig family	0.013
CG11178	CG11178 gene product from transcript CG11178-RA	0.013
nAcRalpha-7E	nicotinic Acetylcholine Receptor alpha 7E	0.013
ST6Gal	Sialyltransferase	0.013
Letm1	CG4589 gene product from transcript CG4589-RB	0.013
Ciao1	CG12797 gene product from transcript CG12797-RA	0.013
CG9335	CG9335 gene product from transcript CG9335-RA	0.013
CG11347	CG11347 gene product from transcript CG11347-RE	0.013
Dap160	Dynamin associated protein 160	0.013
G-oalpha47A	G protein oalpha 47A	0.013
bbg	big bang	0.013
CG8907	CG8907 gene product from transcript CG8907-RA	0.013
CG17471	CG17471 gene product from transcript CG17471-RB	0.013
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.013
Syx4	Syntaxin 4	0.013
galectin	CG11372 gene product from transcript CG11372-RA	0.013
glo	glorund	0.013
CG9947	CG9947 gene product from transcript CG9947-RA	0.013
twf	twinfilin	0.013
sima	similar	0.013
CG3558	CG3558 gene product from transcript CG3558-RC	0.013
rtet	tetracycline resistance	0.013
Nrx-IV	Neurexin IV	0.012
CG4950	CG4950 gene product from transcript CG4950-RB	0.012
cpx	complexin	0.012
5-HT7	Serotonin receptor 7	0.012
CG4025	CG4025 gene product from transcript CG4025-RA	0.012
CG12424	CG12424 gene product from transcript CG12424-RC	0.012
Myo28B1	CG6976 gene product from transcript CG6976-RB	0.012
RagA	CG11968 gene product from transcript CG11968-RA	0.012
CG3529	CG3529 gene product from transcript CG3529-RB	0.012
Su(z)2	Suppressor of zeste 2	0.012
Pka-R2	cAMP-dependent protein kinase R2	0.012
Muc91C	Mucin 91C	0.012
CG6765	CG6765 gene product from transcript CG6765-RA	0.012
CG31998	CG31998 gene product from transcript CG31998-RA	0.012
CG8334	CG8334 gene product from transcript CG8334-RA	0.012
CG7632	CG7632 gene product from transcript CG7632-RA	0.012
Fas3	Fasciclin 3	0.012
CG11537	CG11537 gene product from transcript CG11537-RD	0.012
CycJ	Cyclin J	0.012
CSN1b	COP9 complex homolog subunit 1 b	0.012
CG12241	CG12241 gene product from transcript CG12241-RA	0.012
Pld	Phospholipase D	0.012	Yeast Rat
CG32528	CG32528 gene product from transcript CG32528-RA	0.012
pck	pickel	0.012
CG32512	CG32512 gene product from transcript CG32512-RA	0.012
S6kII	RPS6-protein kinase-II	0.012
Csas	CMP-sialic acid synthase	0.012
ctp	cut up	0.012
Su(Tpl)	CG32217 gene product from transcript CG32217-RB	0.012
CDase	Ceramidase	0.012
Cyp18a1	Cytochrome P450-18a1	0.012
Ac76E	Adenylyl cyclase 76E	0.012
mAcR-60C	muscarinic Acetylcholine Receptor 60C	0.012
CG15764	CG15764 gene product from transcript CG15764-RA	0.012
Ric	Ras which interacts with Calmodulin	0.012
beat-Ic	beaten path Ic	0.012
Yp2	Yolk protein 2	0.012
vib	vibrator	0.012
CG32544	CG32544 gene product from transcript CG32544-RA	0.012
CG6812	CG6812 gene product from transcript CG6812-RA	0.012
CG8605	CG8605 gene product from transcript CG8605-RA	0.012
CG3493	CG3493 gene product from transcript CG3493-RA	0.011
TSG101	tumor suppressor protein 101	0.011	Human
TER94	CG2331 gene product from transcript CG2331-RA	0.011
CG2052	CG2052 gene product from transcript CG2052-RB	0.011
CG12071	CG12071 gene product from transcript CG12071-RB	0.011
Past1	Putative Achaete Scute Target 1	0.011
Syn	Synapsin	0.011
Syx6	Syntaxin 6	0.011
CG34400	CG34400 gene product from transcript CG34400-RD	0.011
PEK	pancreatic eIF-2alpha kinase	0.011
CG6178	CG6178 gene product from transcript CG6178-RA	0.011
betaggt-II	beta subunit of type II geranylgeranyl transferase	0.011
Sr-CI	Scavenger receptor class C, type I	0.011
Tsp3A	Tetraspanin 3A	0.011
cenG1A	centaurin gamma 1A	0.011
Osbp	Oxysterol binding protein	0.011
gbb	glass bottom boat	0.011
stet	stem cell tumor	0.011
CG6954	CG6954 gene product from transcript CG6954-RB	0.011
CG5731	CG5731 gene product from transcript CG5731-RA	0.011
AP-47	CG9388 gene product from transcript CG9388-RA	0.010
Prestin	CG5485 gene product from transcript CG5485-RA	0.010
CG1371	CG1371 gene product from transcript CG1371-RA	0.010
usnp	ubisnap	0.010
CG3573	CG3573 gene product from transcript CG3573-RA	0.010
CG8569	CG8569 gene product from transcript CG8569-RA	0.010
Ppt1	Palmitoyl-protein thioesterase 1	0.010
Xbp1	X box binding protein-1	0.010
CG40127	CG40127 gene product from transcript CG40127-RA	0.010
Hip14	Huntingtin-interacting protein 14	0.010
CG8202	CG8202 gene product from transcript CG8202-RA	0.010
CG10445	CG10445 gene product from transcript CG10445-RC	0.010
Pkn	Protein kinase related to protein kinase N	0.010
gfA	giant fibre A	0.010
CG11306	CG11306 gene product from transcript CG11306-RA	0.010
Glut1	Glucose transporter 1	0.010
Pvf1	PDGF- and VEGF-related factor 1	0.010