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Homo sapiens

39 genes annotated in human

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protein monoubiquitination

GO:0006513

Addition of a single ubiquitin group to a protein.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein monoubiquitination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein monoubiquitination" (in gray)

Name	Description	Probability	Func Analog Organism
RNF11	ring finger protein 11	1.000
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	1.000
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	1.000	Human Yeast
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	1.000
RNF2	ring finger protein 2	1.000
RNF5	ring finger protein 5	0.999
RING1	ring finger protein 1	0.998
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.996	Human Yeast
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.994
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.988
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.980
RNF20	ring finger protein 20	0.979
ZNRF1	zinc and ring finger 1	0.970
BCOR	BCL6 corepressor	0.951
TRIM39	tripartite motif containing 39	0.947	Human
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.943	Yeast
CUL1	cullin 1	0.933	Mouse
CBX8	chromobox homolog 8	0.910
XIAP	X-linked inhibitor of apoptosis	0.903	Human
RNF126	ring finger protein 126	0.898
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.897	Human Yeast
CUL4A	cullin 4A	0.884	Human
ARIH2	ariadne homolog 2 (Drosophila)	0.873
UBXN7	UBX domain protein 7	0.845
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.839
DZIP3	DAZ interacting protein 3, zinc finger	0.832
SKP1	S-phase kinase-associated protein 1	0.820
RNF111	ring finger protein 111	0.773
UBA1	ubiquitin-like modifier activating enzyme 1	0.769
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.760
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.716
BMI1	BMI1 polycomb ring finger oncogene	0.714	Human
CUL3	cullin 3	0.712
SIAH1	seven in absentia homolog 1 (Drosophila)	0.692
RAD18	RAD18 homolog (S. cerevisiae)	0.678
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.677
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.653
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.631
KLHL12	kelch-like 12 (Drosophila)	0.627
RYBP	RING1 and YY1 binding protein	0.622
PCGF1	polycomb group ring finger 1	0.616
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.590
DDB1	damage-specific DNA binding protein 1, 127kDa	0.569
MIB1	mindbomb homolog 1 (Drosophila)	0.552
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.530
CBX7	chromobox homolog 7	0.523
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.516
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.483	Yeast
YY1	YY1 transcription factor	0.432
RNF114	ring finger protein 114	0.431
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.430
TCEA1	transcription elongation factor A (SII), 1	0.379
MARCH7	membrane-associated ring finger (C3HC4) 7	0.376
EED	embryonic ectoderm development	0.373
PEX5	peroxisomal biogenesis factor 5	0.345
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.322	Yeast Mouse
RNF14	ring finger protein 14	0.313
CBX6	chromobox homolog 6	0.293
PCGF3	polycomb group ring finger 3	0.261	Human
TRIM43	tripartite motif containing 43	0.258
MARCH5	membrane-associated ring finger (C3HC4) 5	0.245
BTRC	beta-transducin repeat containing	0.243
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.240
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.239
RFWD2	ring finger and WD repeat domain 2	0.230
TRAF6	TNF receptor-associated factor 6	0.229
UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)	0.216	Human
FBXW11	F-box and WD repeat domain containing 11	0.214
USP11	ubiquitin specific peptidase 11	0.212
TRAF3	TNF receptor-associated factor 3	0.208
RNF4	ring finger protein 4	0.208
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.204
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.197
RNF10	ring finger protein 10	0.194
WDR61	WD repeat domain 61	0.192
UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	0.189	Human
TRIM5	tripartite motif containing 5	0.188	Human
ZNF263	zinc finger protein 263	0.187
KDM2B	lysine (K)-specific demethylase 2B	0.182
MKRN1	makorin ring finger protein 1	0.182
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.177
TRIM27	tripartite motif containing 27	0.171	Human
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.170
PCNA	proliferating cell nuclear antigen	0.164
RNF38	ring finger protein 38	0.153
CNOT4	CCR4-NOT transcription complex, subunit 4	0.152
WNK4	WNK lysine deficient protein kinase 4	0.152
CUL4B	cullin 4B	0.150
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.148	Yeast
TRIM32	tripartite motif containing 32	0.145
FANCM	Fanconi anemia, complementation group M	0.143
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.137
CHFR	checkpoint with forkhead and ring finger domains	0.132
PCGF2	polycomb group ring finger 2	0.128	Human
INO80	INO80 homolog (S. cerevisiae)	0.126
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.124	Human Yeast
XPC	xeroderma pigmentosum, complementation group C	0.122
RNF130	ring finger protein 130	0.113
CBX4	chromobox homolog 4	0.110
ANKRD13A	ankyrin repeat domain 13A	0.108
BFAR	bifunctional apoptosis regulator	0.100
UBXN1	UBX domain protein 1	0.097
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.094
VPRBP	Vpr (HIV-1) binding protein	0.092
ZNF746	zinc finger protein 746	0.086
TRIM8	tripartite motif containing 8	0.086
PCGF5	polycomb group ring finger 5	0.086	Human
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.085
MED28	mediator complex subunit 28	0.084
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.084
ING2	inhibitor of growth family, member 2	0.084
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.083
INF2	inverted formin, FH2 and WH2 domain containing	0.083
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.077
RNF185	ring finger protein 185	0.076
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.075
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.073
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.073
ZFYVE9	zinc finger, FYVE domain containing 9	0.070
PRMT6	protein arginine methyltransferase 6	0.070
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.069
RLIM	ring finger protein, LIM domain interacting	0.069
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.067
OPTN	optineurin	0.067
ANKRD32	ankyrin repeat domain 32	0.065
KLHL2	kelch-like 2, Mayven (Drosophila)	0.062	Human
AMFR	autocrine motility factor receptor	0.062
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.059
CUL5	cullin 5	0.055
TRIM26	tripartite motif containing 26	0.054
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.053
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.052	Yeast
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.051
RBBP5	retinoblastoma binding protein 5	0.047
BAK1	BCL2-antagonist/killer 1	0.046
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.046
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.046
SP100	SP100 nuclear antigen	0.045
USP15	ubiquitin specific peptidase 15	0.045
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.045
TRAF2	TNF receptor-associated factor 2	0.045
NCS1	neuronal calcium sensor 1	0.043
UBC	ubiquitin C	0.042
FANCB	Fanconi anemia, complementation group B	0.042
FBXW5	F-box and WD repeat domain containing 5	0.041
MEX3B	mex-3 homolog B (C. elegans)	0.039
POLH	polymerase (DNA directed), eta	0.038
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.038
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.038
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.037
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.036
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.034
BIRC8	baculoviral IAP repeat containing 8	0.033	Human
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.033
FBXL15	F-box and leucine-rich repeat protein 15	0.033
PJA2	praja ring finger 2	0.032
TRIM21	tripartite motif containing 21	0.031
TRIM23	tripartite motif containing 23	0.029
TRIM34	tripartite motif containing 34	0.029
WDR20	WD repeat domain 20	0.028
ATXN3	ataxin 3	0.028
UBOX5	U-box domain containing 5	0.027
USP12	ubiquitin specific peptidase 12	0.027
DCTN4	dynactin 4 (p62)	0.027
WNK1	WNK lysine deficient protein kinase 1	0.027
RNF166	ring finger protein 166	0.027
YAF2	YY1 associated factor 2	0.027	Human
ZNF473	zinc finger protein 473	0.027
SKP2	S-phase kinase-associated protein 2 (p45)	0.026
TRIM11	tripartite motif containing 11	0.026	Human
TRIM35	tripartite motif containing 35	0.026
VCP	valosin containing protein	0.026
DDB2	damage-specific DNA binding protein 2, 48kDa	0.025
MSL1	male-specific lethal 1 homolog (Drosophila)	0.025
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.025
MID1	midline 1 (Opitz/BBB syndrome)	0.025
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.025
CXXC5	CXXC finger protein 5	0.025
TRAF1	TNF receptor-associated factor 1	0.025
CUL2	cullin 2	0.025
TRIM25	tripartite motif containing 25	0.024
WDR5	WD repeat domain 5	0.024
PEX14	peroxisomal biogenesis factor 14	0.024
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.024
MSL2	male-specific lethal 2 homolog (Drosophila)	0.023
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.022
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.022
TRAF4	TNF receptor-associated factor 4	0.021
RNF40	ring finger protein 40	0.021
MYST1	MYST histone acetyltransferase 1	0.021
RNF26	ring finger protein 26	0.021
WDR26	WD repeat domain 26	0.021
RAD23A	RAD23 homolog A (S. cerevisiae)	0.021
VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	0.021
WDR48	WD repeat domain 48	0.020	Mouse
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.020
FANCD2	Fanconi anemia, complementation group D2	0.020
RNF181	ring finger protein 181	0.019
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.019
LRR1	leucine rich repeat protein 1	0.019
CYLD	cylindromatosis (turban tumor syndrome)	0.019
YLPM1	YLP motif containing 1	0.019
PINK1	PTEN induced putative kinase 1	0.019
FBXO7	F-box protein 7	0.019
CAND1	cullin-associated and neddylation-dissociated 1	0.019
PCGF6	polycomb group ring finger 6	0.018	Human
HCFC1	host cell factor C1 (VP16-accessory protein)	0.018
PIAS3	protein inhibitor of activated STAT, 3	0.018
SNX9	sorting nexin 9	0.018
ANXA1	annexin A1	0.018
PARP9	poly (ADP-ribose) polymerase family, member 9	0.018
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.018	Yeast
SPRYD5	SPRY domain containing 5	0.018
N4BP1	NEDD4 binding protein 1	0.017
BTBD10	BTB (POZ) domain containing 10	0.017
C16orf75	chromosome 16 open reading frame 75	0.017
RMND5B	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.017
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.017
DDIT4	DNA-damage-inducible transcript 4	0.017
RNF165	ring finger protein 165	0.016
DTX3L	deltex 3-like (Drosophila)	0.016
RSPRY1	ring finger and SPRY domain containing 1	0.016
MEX3C	mex-3 homolog C (C. elegans)	0.016
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.015
SPOP	speckle-type POZ protein	0.015
NUDCD3	NudC domain containing 3	0.015
FBXO33	F-box protein 33	0.015
DPP3	dipeptidyl-peptidase 3	0.015
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.015
DAXX	death-domain associated protein	0.015
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.015
SMAD4	SMAD family member 4	0.015
RIPK2	receptor-interacting serine-threonine kinase 2	0.015
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.015
FDXR	ferredoxin reductase	0.015
USP46	ubiquitin specific peptidase 46	0.015
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.015
DIAPH3	diaphanous homolog 3 (Drosophila)	0.014
UBASH3B	ubiquitin associated and SH3 domain containing B	0.014
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.014
RIPK3	receptor-interacting serine-threonine kinase 3	0.014
HIST2H2AC	histone cluster 2, H2ac	0.014
RIPK4	receptor-interacting serine-threonine kinase 4	0.014
CHD8	chromodomain helicase DNA binding protein 8	0.014
SFN	stratifin	0.014
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.014
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.014
UBASH3A	ubiquitin associated and SH3 domain containing A	0.014
NCALD	neurocalcin delta	0.013
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.013
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.013
RNF115	ring finger protein 115	0.013	Human
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.013
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.013	Human
ZNF512B	zinc finger protein 512B	0.013
KLHDC5	kelch domain containing 5	0.013
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.013
AHCYL1	adenosylhomocysteinase-like 1	0.013
CORO7	coronin 7	0.013
PDCD2	programmed cell death 2	0.013
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.013
BRD2	bromodomain containing 2	0.013
MED15	mediator complex subunit 15	0.012
ACYP1	acylphosphatase 1, erythrocyte (common) type	0.012
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.012
WAC	WW domain containing adaptor with coiled-coil	0.012
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.012
ZBTB33	zinc finger and BTB domain containing 33	0.012
SPIN4	spindlin family, member 4	0.012
UBE2G2	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	0.012
DDA1	DET1 and DDB1 associated 1	0.012
SNIP1	Smad nuclear interacting protein 1	0.012
IRF2	interferon regulatory factor 2	0.012
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.012
KIF9	kinesin family member 9	0.011
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.011
PELI1	pellino homolog 1 (Drosophila)	0.011
TRIM2	tripartite motif containing 2	0.011
VSNL1	visinin-like 1	0.011
SNX16	sorting nexin 16	0.011
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.011
RNF103	ring finger protein 103	0.011
PPIL4	peptidylprolyl isomerase (cyclophilin)-like 4	0.011
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.011
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.011
BRD1	bromodomain containing 1	0.011
CSDE1	cold shock domain containing E1, RNA-binding	0.011
JUB	jub, ajuba homolog (Xenopus laevis)	0.011
TRIM52	tripartite motif containing 52	0.011
ZFAND5	zinc finger, AN1-type domain 5	0.011
DPY19L4	dpy-19-like 4 (C. elegans)	0.011
PLEKHA3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	0.010
CDT1	chromatin licensing and DNA replication factor 1	0.010
PACRG	PARK2 co-regulated	0.010
KDM6A	lysine (K)-specific demethylase 6A	0.010
SP110	SP110 nuclear body protein	0.010
ZRANB1	zinc finger, RAN-binding domain containing 1	0.010
AP3M1	adaptor-related protein complex 3, mu 1 subunit	0.010
IRF9	interferon regulatory factor 9	0.010
CDCA7	cell division cycle associated 7	0.010
PIAS4	protein inhibitor of activated STAT, 4	0.010
WDR5B	WD repeat domain 5B	0.010
TRIM41	tripartite motif containing 41	0.010	Human
MR1	major histocompatibility complex, class I-related	0.010