IMP
Process View
notch signaling pathway
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "notch signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NOTCH1 | notch 1 | 0.990 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.959 | ||
| JAG1 | jagged 1 | 0.895 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.833 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.770 | Fly | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.662 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.651 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.625 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.573 | ||
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.566 | Fly | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.531 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.511 | ||
| HDAC1 | histone deacetylase 1 | 0.510 | Worm | |
| NOTCH3 | notch 3 | 0.491 | Human Zebrafish Mouse Rat Fly | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.477 | ||
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.458 | ||
| ATP13A2 | ATPase type 13A2 | 0.436 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.434 | ||
| CP110 | CP110 protein | 0.366 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.355 | ||
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.328 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.309 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.300 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.272 | ||
| LAT | linker for activation of T cells | 0.269 | ||
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.256 | ||
| CREBBP | CREB binding protein | 0.251 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.249 | ||
| SMAD4 | SMAD family member 4 | 0.231 | ||
| MAGEA3 | melanoma antigen family A, 3 | 0.219 | ||
| ADAM10 | ADAM metallopeptidase domain 10 | 0.212 | Mouse Worm | |
| DBNL | drebrin-like | 0.209 | ||
| CSNK1E | casein kinase 1, epsilon | 0.199 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.197 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.190 | Mouse | |
| SKIL | SKI-like oncogene | 0.189 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.182 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.182 | ||
| CSNK1D | casein kinase 1, delta | 0.182 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.176 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.161 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.158 | ||
| MAGEA6 | melanoma antigen family A, 6 | 0.155 | Human | |
| GDA | guanine deaminase | 0.151 | ||
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.146 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.145 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.144 | ||
| DNM1 | dynamin 1 | 0.140 | Fly | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.135 | ||
| EGFR | epidermal growth factor receptor | 0.135 | ||
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.133 | ||
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.129 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.128 | ||
| RALB | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 0.127 | Fly | |
| SMAD2 | SMAD family member 2 | 0.125 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.124 | Fly | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.124 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.124 | ||
| NAP1L5 | nucleosome assembly protein 1-like 5 | 0.123 | ||
| CTAG1B | cancer/testis antigen 1B | 0.123 | ||
| MAGEA12 | melanoma antigen family A, 12 | 0.121 | Human | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.116 | ||
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.116 | ||
| RUNX1 | runt-related transcription factor 1 | 0.115 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.115 | Fly | |
| CDAN1 | congenital dyserythropoietic anemia, type I | 0.109 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.103 | ||
| ZNF496 | zinc finger protein 496 | 0.102 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.100 | ||
| SYK | spleen tyrosine kinase | 0.099 | ||
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.099 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.099 | ||
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.099 | ||
| SNX9 | sorting nexin 9 | 0.096 | ||
| AXIN1 | axin 1 | 0.094 | ||
| EXOC7 | exocyst complex component 7 | 0.090 | ||
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.087 | ||
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.086 | ||
| PRKCZ | protein kinase C, zeta | 0.086 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.085 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.082 | ||
| ASF1B | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.080 | Fly | |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.079 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.077 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.076 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.076 | ||
| RBPMS | RNA binding protein with multiple splicing | 0.075 | ||
| YY1 | YY1 transcription factor | 0.073 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.072 | ||
| TEKT4 | tektin 4 | 0.072 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.070 | ||
| DLL1 | delta-like 1 (Drosophila) | 0.068 | ||
| PTCH1 | patched 1 | 0.067 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.066 | ||
| PML | promyelocytic leukemia | 0.065 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.065 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.064 | ||
| TCF4 | transcription factor 4 | 0.064 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.062 | Fly | |
| CBX5 | chromobox homolog 5 | 0.062 | ||
| RALBP1 | ralA binding protein 1 | 0.062 | ||
| CCND3 | cyclin D3 | 0.061 | ||
| BBS2 | Bardet-Biedl syndrome 2 | 0.061 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.060 | ||
| NOTCH2 | notch 2 | 0.058 | Human Fly | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.057 | ||
| JAK2 | Janus kinase 2 | 0.056 | ||
| JAG2 | jagged 2 | 0.056 | Human Fly | |
| ZNF148 | zinc finger protein 148 | 0.054 | ||
| FLNA | filamin A, alpha | 0.053 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.053 | ||
| NUMB | numb homolog (Drosophila) | 0.052 | Mouse | |
| DNM2 | dynamin 2 | 0.051 | Fly | |
| SNIP1 | Smad nuclear interacting protein 1 | 0.051 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.050 | ||
| WT1 | Wilms tumor 1 | 0.049 | ||
| MAGEA1 | melanoma antigen family A, 1 (directs expression of antigen MZ2-E) | 0.049 | ||
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.047 | ||
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.046 | ||
| CHMP1A | chromatin modifying protein 1A | 0.046 | ||
| BTRC | beta-transducin repeat containing | 0.045 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.044 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.043 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.042 | ||
| CPD | carboxypeptidase D | 0.042 | ||
| TRIM28 | tripartite motif containing 28 | 0.042 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.041 | ||
| SP1 | Sp1 transcription factor | 0.041 | ||
| EXOC5 | exocyst complex component 5 | 0.041 | ||
| FSTL1 | follistatin-like 1 | 0.041 | ||
| FCHO2 | FCH domain only 2 | 0.041 | ||
| LNX1 | ligand of numb-protein X 1 | 0.039 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.039 | Fly | |
| PITX1 | paired-like homeodomain 1 | 0.039 | ||
| RHOXF2 | Rhox homeobox family, member 2 | 0.039 | ||
| LIMD1 | LIM domains containing 1 | 0.039 | ||
| E2F1 | E2F transcription factor 1 | 0.038 | ||
| MYO6 | myosin VI | 0.038 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.037 | ||
| C20orf20 | chromosome 20 open reading frame 20 | 0.037 | ||
| MAGEA4 | melanoma antigen family A, 4 | 0.036 | Human | |
| WWOX | WW domain containing oxidoreductase | 0.036 | ||
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.036 | ||
| UBXN4 | UBX domain protein 4 | 0.036 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.035 | ||
| CCND1 | cyclin D1 | 0.035 | ||
| ATXN3 | ataxin 3 | 0.035 | ||
| KDM2A | lysine (K)-specific demethylase 2A | 0.035 | ||
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.034 | ||
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.034 | ||
| CXXC5 | CXXC finger protein 5 | 0.033 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.033 | ||
| SGSM2 | small G protein signaling modulator 2 | 0.032 | ||
| GLUL | glutamate-ammonia ligase | 0.032 | ||
| DAXX | death-domain associated protein | 0.032 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.032 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.031 | ||
| NCK1 | NCK adaptor protein 1 | 0.031 | ||
| HDAC3 | histone deacetylase 3 | 0.030 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.030 | ||
| MAGEA2 | melanoma antigen family A, 2 | 0.030 | Human | |
| SATB2 | SATB homeobox 2 | 0.030 | ||
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.030 | ||
| TBL1X | transducin (beta)-like 1X-linked | 0.030 | Fly | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.030 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.030 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.030 | ||
| SCAMP1 | secretory carrier membrane protein 1 | 0.029 | ||
| PCM1 | pericentriolar material 1 | 0.029 | ||
| TOX4 | TOX high mobility group box family member 4 | 0.029 | ||
| FGF18 | fibroblast growth factor 18 | 0.028 | ||
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 0.028 | ||
| RADIL | Ras association and DIL domains | 0.028 | ||
| CBFB | core-binding factor, beta subunit | 0.028 | ||
| CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 0.028 | ||
| RAB10 | RAB10, member RAS oncogene family | 0.028 | ||
| PJA1 | praja ring finger 1 | 0.028 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.028 | ||
| NAGK | N-acetylglucosamine kinase | 0.027 | ||
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.027 | ||
| MTMR4 | myotubularin related protein 4 | 0.027 | ||
| MAGEA5 | melanoma antigen family A, 5 | 0.026 | ||
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.026 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.026 | Mouse | |
| CREB1 | cAMP responsive element binding protein 1 | 0.026 | ||
| PAPOLA | poly(A) polymerase alpha | 0.026 | ||
| PTBP2 | polypyrimidine tract binding protein 2 | 0.026 | Fly | |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.026 | ||
| SCARB2 | scavenger receptor class B, member 2 | 0.026 | ||
| HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.026 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.026 | ||
| MAGEC1 | melanoma antigen family C, 1 | 0.025 | Human | |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.025 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.025 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.025 | ||
| AMPH | amphiphysin | 0.025 | ||
| ZFPM1 | zinc finger protein, multitype 1 | 0.024 | ||
| CHAC1 | ChaC, cation transport regulator homolog 1 (E. coli) | 0.024 | ||
| LMAN1 | lectin, mannose-binding, 1 | 0.024 | ||
| RAB5A | RAB5A, member RAS oncogene family | 0.024 | ||
| TBX5 | T-box 5 | 0.024 | ||
| ALX4 | ALX homeobox 4 | 0.023 | ||
| TONSL | tonsoku-like, DNA repair protein | 0.023 | ||
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.023 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.023 | ||
| KITLG | KIT ligand | 0.023 | ||
| FAM156A | family with sequence similarity 156, member A | 0.023 | ||
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.022 | ||
| MBNL1 | muscleblind-like (Drosophila) | 0.022 | ||
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.022 | ||
| TTC3 | tetratricopeptide repeat domain 3 | 0.022 | ||
| RIC8A | resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | 0.022 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.022 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.022 | ||
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.021 | ||
| CD164 | CD164 molecule, sialomucin | 0.021 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.021 | ||
| WNT10A | wingless-type MMTV integration site family, member 10A | 0.021 | Human | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.021 | ||
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.021 | ||
| ATXN1 | ataxin 1 | 0.021 | ||
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.021 | ||
| MCC | mutated in colorectal cancers | 0.021 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.021 | ||
| EGR1 | early growth response 1 | 0.020 | ||
| TXN | thioredoxin | 0.020 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.020 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.020 | Human | |
| AGFG1 | ArfGAP with FG repeats 1 | 0.020 | ||
| EP300 | E1A binding protein p300 | 0.020 | ||
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.020 | ||
| CNTROB | centrobin, centrosomal BRCA2 interacting protein | 0.020 | ||
| BMP4 | bone morphogenetic protein 4 | 0.019 | ||
| HIST1H3B | histone cluster 1, H3b | 0.019 | ||
| FLNB | filamin B, beta | 0.019 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.019 | ||
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.019 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.019 | Fly | |
| KRT5 | keratin 5 | 0.019 | ||
| NEU4 | sialidase 4 | 0.019 | ||
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.019 | ||
| FAM46D | family with sequence similarity 46, member D | 0.019 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.019 | ||
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.018 | ||
| WDR20 | WD repeat domain 20 | 0.018 | ||
| NPAS1 | neuronal PAS domain protein 1 | 0.018 | ||
| ABI1 | abl-interactor 1 | 0.018 | ||
| TNS3 | tensin 3 | 0.018 | ||
| MAGEB2 | melanoma antigen family B, 2 | 0.018 | Human | |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.018 | Fly | |
| ZNRF1 | zinc and ring finger 1 | 0.018 | ||
| ASB13 | ankyrin repeat and SOCS box containing 13 | 0.018 | ||
| PKP4 | plakophilin 4 | 0.018 | ||
| ZNF420 | zinc finger protein 420 | 0.018 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.018 | ||
| PCDH9 | protocadherin 9 | 0.018 | ||
| S100A4 | S100 calcium binding protein A4 | 0.018 | ||
| NCS1 | neuronal calcium sensor 1 | 0.018 | ||
| SH3GL1 | SH3-domain GRB2-like 1 | 0.017 | ||
| CCNF | cyclin F | 0.017 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.017 | ||
| FKBP8 | FK506 binding protein 8, 38kDa | 0.017 | ||
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.017 | ||
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.017 | Human | |
| IRS1 | insulin receptor substrate 1 | 0.017 | ||
| S1PR5 | sphingosine-1-phosphate receptor 5 | 0.017 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.016 | ||
| TRAM1 | translocation associated membrane protein 1 | 0.016 | ||
| UBQLN1 | ubiquilin 1 | 0.016 | ||
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 0.016 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.016 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.016 | ||
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 0.016 | ||
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.016 | ||
| EBF1 | early B-cell factor 1 | 0.016 | ||
| CDK4 | cyclin-dependent kinase 4 | 0.016 | ||
| TPT1 | tumor protein, translationally-controlled 1 | 0.016 | ||
| CLDN7 | claudin 7 | 0.016 | ||
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.016 | ||
| CUL7 | cullin 7 | 0.016 | ||
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.016 | ||
| ESPN | espin | 0.016 | ||
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.016 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.016 | ||
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.016 | ||
| BBS9 | Bardet-Biedl syndrome 9 | 0.016 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.016 | ||
| MOAP1 | modulator of apoptosis 1 | 0.016 | ||
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.015 | ||
| RAB11A | RAB11A, member RAS oncogene family | 0.015 | ||
| RB1 | retinoblastoma 1 | 0.015 | ||
| AHR | aryl hydrocarbon receptor | 0.015 | ||
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.015 | ||
| DLL3 | delta-like 3 (Drosophila) | 0.015 | Human Zebrafish Rat Fly | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.015 | ||
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.015 | ||
| PPAP2B | phosphatidic acid phosphatase type 2B | 0.015 | ||
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.015 | ||
| MTF1 | metal-regulatory transcription factor 1 | 0.015 | ||
| SRI | sorcin | 0.014 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.014 | ||
| MECP2 | methyl CpG binding protein 2 (Rett syndrome) | 0.014 | ||
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.014 | ||
| SMAD3 | SMAD family member 3 | 0.014 | ||
| LAMTOR1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | 0.014 | ||
| TBP | TATA box binding protein | 0.014 | ||
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.014 | ||
| FAM193A | family with sequence similarity 193, member A | 0.014 | ||
| GATA2 | GATA binding protein 2 | 0.014 | ||
| HDAC5 | histone deacetylase 5 | 0.014 | ||
| CEP290 | centrosomal protein 290kDa | 0.014 | ||
| CEP164 | centrosomal protein 164kDa | 0.014 | ||
| MED13L | mediator complex subunit 13-like | 0.014 | ||
| NOG | noggin | 0.014 | ||
| ALX3 | ALX homeobox 3 | 0.014 | ||
| PAX2 | paired box 2 | 0.014 | ||
| ATXN1L | ataxin 1-like | 0.014 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.014 | ||
| IL11 | interleukin 11 | 0.014 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.014 | ||
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.014 | ||
| RBM11 | RNA binding motif protein 11 | 0.013 | ||
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.013 | ||
| E2F2 | E2F transcription factor 2 | 0.013 | ||
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.013 | ||
| HES1 | hairy and enhancer of split 1, (Drosophila) | 0.013 | ||
| WDR48 | WD repeat domain 48 | 0.013 | ||
| RALY | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 0.013 | ||
| DAZAP2 | DAZ associated protein 2 | 0.013 | ||
| SURF4 | surfeit 4 | 0.013 | ||
| HOXC8 | homeobox C8 | 0.013 | ||
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.013 | ||
| FBLN1 | fibulin 1 | 0.013 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.013 | ||
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.013 | ||
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.013 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.013 | ||
| MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.013 | ||
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.013 | ||
| TFDP1 | transcription factor Dp-1 | 0.013 | ||
| ABI2 | abl-interactor 2 | 0.013 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.013 | Human | |
| MMS22L | MMS22-like, DNA repair protein | 0.013 | ||
| MUC1 | mucin 1, cell surface associated | 0.013 | ||
| TRIM69 | tripartite motif containing 69 | 0.013 | ||
| TP73 | tumor protein p73 | 0.013 | Human | |
| TRIM27 | tripartite motif containing 27 | 0.012 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.012 | ||
| POU3F1 | POU class 3 homeobox 1 | 0.012 | ||
| MSX1 | msh homeobox 1 | 0.012 | ||
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.012 | Fly | |
| MBD1 | methyl-CpG binding domain protein 1 | 0.012 | ||
| MAGEA10 | melanoma antigen family A, 10 | 0.012 | Human | |
| LIMK2 | LIM domain kinase 2 | 0.012 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.012 | ||
| CDX2 | caudal type homeobox 2 | 0.012 | ||
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.012 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.012 | ||
| DIDO1 | death inducer-obliterator 1 | 0.012 | ||
| DHH | desert hedgehog | 0.012 | ||
| TERT | telomerase reverse transcriptase | 0.012 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.012 | ||
| UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.012 | ||
| CLPB | ClpB caseinolytic peptidase B homolog (E. coli) | 0.012 | ||
| NEUROG2 | neurogenin 2 | 0.012 | ||
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.012 | ||
| INVS | inversin | 0.012 | ||
| FOXN4 | forkhead box N4 | 0.012 | ||
| INHBB | inhibin, beta B | 0.012 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.012 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.012 | ||
| JAK1 | Janus kinase 1 | 0.012 | ||
| EID2B | EP300 interacting inhibitor of differentiation 2B | 0.012 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.012 | Fly | |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.012 | ||
| GDI2 | GDP dissociation inhibitor 2 | 0.012 | ||
| HOXB9 | homeobox B9 | 0.012 | ||
| OTP | orthopedia homeobox | 0.012 | ||
| BHLHE23 | basic helix-loop-helix family, member e23 | 0.011 | ||
| RET | ret proto-oncogene | 0.011 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.011 | ||
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | 0.011 | ||
| SYNJ1 | synaptojanin 1 | 0.011 | ||
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.011 | ||
| NAT15 | N-acetyltransferase 15 (GCN5-related, putative) | 0.011 | ||
| SSR1 | signal sequence receptor, alpha | 0.011 | ||
| HES5 | hairy and enhancer of split 5 (Drosophila) | 0.011 | ||
| TAF4 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | 0.011 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.011 | ||
| PRKCI | protein kinase C, iota | 0.011 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.011 | ||
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.011 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.011 | ||
| OPRD1 | opioid receptor, delta 1 | 0.011 | ||
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.011 | ||
| EPHB3 | EPH receptor B3 | 0.011 | ||
| NOTCH2NL | notch 2 N-terminal like | 0.011 | ||
| RPL3 | ribosomal protein L3 | 0.011 | ||
| SH2B2 | SH2B adaptor protein 2 | 0.011 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.011 | ||
| DDN | dendrin | 0.011 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.011 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.011 | Worm | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.011 | ||
| CTAG2 | cancer/testis antigen 2 | 0.011 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.011 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.011 | ||
| NAMPT | nicotinamide phosphoribosyltransferase | 0.011 | ||
| FEV | FEV (ETS oncogene family) | 0.011 | ||
| EID3 | EP300 interacting inhibitor of differentiation 3 | 0.011 | ||
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.011 | ||
| PRSS8 | protease, serine, 8 | 0.010 | ||
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.010 | ||
| LBX1 | ladybird homeobox 1 | 0.010 | ||
| MAST1 | microtubule associated serine/threonine kinase 1 | 0.010 | ||
| TBX1 | T-box 1 | 0.010 | ||
| PCDHA4 | protocadherin alpha 4 | 0.010 | ||
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.010 | ||
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.010 | ||
| TBX2 | T-box 2 | 0.010 | ||
| GRHL2 | grainyhead-like 2 (Drosophila) | 0.010 | ||
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.010 | ||
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | 0.010 | Fly | |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 0.010 | ||
| EP400 | E1A binding protein p400 | 0.010 | Fly | |
| LRRN2 | leucine rich repeat neuronal 2 | 0.010 | ||
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.010 | ||
| AMOTL1 | angiomotin like 1 | 0.010 | ||
| TTC8 | tetratricopeptide repeat domain 8 | 0.010 | ||
| KDM1A | lysine (K)-specific demethylase 1A | 0.010 | ||
| DLL4 | delta-like 4 (Drosophila) | 0.010 | Human Mouse Fly | |
| HOXB5 | homeobox B5 | 0.010 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.010 | ||
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.010 | ||
| GAGE12D | G antigen 12D | 0.010 | ||
| EGFL7 | EGF-like-domain, multiple 7 | 0.010 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.010 |