IMP

Process View

Mus musculus

25 genes annotated in mouse

cellular response to interferon gamma

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to interferon gamma"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to interferon gamma" (in gray)

Name	Description	Probability	Func Analog Organism
Stat3	signal transducer and activator of transcription 3	0.995	Mouse
Lepr	leptin receptor	0.972
Stat1	signal transducer and activator of transcription 1	0.965
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.954
Igtp	interferon gamma induced GTPase	0.947
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.931
Gbp7	guanylate binding protein 7	0.891
Gbp2	guanylate binding protein 2	0.882
Iigp1	interferon inducible GTPase 1	0.879
Irf9	interferon regulatory factor 9	0.866	Mouse
Lyz2	lysozyme 2	0.860
Irgm1	immunity-related GTPase family M member 1	0.850
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.849
Irgm2	immunity-related GTPase family M member 2	0.842
Gbp3	guanylate binding protein 3	0.842
Stat5b	signal transducer and activator of transcription 5B	0.835	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.799
Tgfb1	transforming growth factor, beta 1	0.699
Il6	interleukin 6	0.684
Tgtp2	T-cell specific GTPase 2	0.664
H2-Eb1	histocompatibility 2, class II antigen E beta	0.662	Mouse
Casp1	caspase 1	0.640
Trim21	tripartite motif-containing 21	0.608
Ccr2	chemokine (C-C motif) receptor 2	0.588
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.556
Csf1	colony stimulating factor 1 (macrophage)	0.535
Il1r1	interleukin 1 receptor, type I	0.528
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.509
Irf8	interferon regulatory factor 8	0.487	Mouse
Cxcl10	chemokine (C-X-C motif) ligand 10	0.434
Usp18	ubiquitin specific peptidase 18	0.412
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.399
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.382
Jak2	Janus kinase 2	0.375	Rat
Ifi47	interferon gamma inducible protein 47	0.369
Tapbp	TAP binding protein	0.335
Cxcl9	chemokine (C-X-C motif) ligand 9	0.301
Aim2	absent in melanoma 2	0.301
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.299
Irf1	interferon regulatory factor 1	0.294
Stat2	signal transducer and activator of transcription 2	0.282	Mouse
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.273
Socs1	suppressor of cytokine signaling 1	0.259	Zebrafish
Pparg	peroxisome proliferator activated receptor gamma	0.250	Human
Ifng	interferon gamma	0.243
Stat5a	signal transducer and activator of transcription 5A	0.239	Mouse
Il10	interleukin 10	0.217
Lep	leptin	0.209
Gbp6	guanylate binding protein 6	0.207
Icam1	intercellular adhesion molecule 1	0.182
Uba7	ubiquitin-like modifier activating enzyme 7	0.176
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.175
Ccl8	chemokine (C-C motif) ligand 8	0.173
Ncoa3	nuclear receptor coactivator 3	0.158
Il4ra	interleukin 4 receptor, alpha	0.154
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.150
Ccl12	chemokine (C-C motif) ligand 12	0.147
Parp14	poly (ADP-ribose) polymerase family, member 14	0.143
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.139
AW112010	expressed sequence AW112010	0.136
Irf7	interferon regulatory factor 7	0.136	Mouse
Mx2	myxovirus (influenza virus) resistance 2	0.134
Tlr4	toll-like receptor 4	0.131
Trim30a	tripartite motif-containing 30A	0.127
H2-DMa	histocompatibility 2, class II, locus DMa	0.121
Rsad2	radical S-adenosyl methionine domain containing 2	0.121
Ccl5	chemokine (C-C motif) ligand 5	0.109	Human
Ly86	lymphocyte antigen 86	0.107
H2-Q7	histocompatibility 2, Q region locus 7	0.106
H2-K1	histocompatibility 2, K1, K region	0.103
Il10ra	interleukin 10 receptor, alpha	0.102
Cxcl2	chemokine (C-X-C motif) ligand 2	0.098
Ptgs2	prostaglandin-endoperoxide synthase 2	0.097
Pycard	PYD and CARD domain containing	0.096
Prlr	prolactin receptor	0.094
Dock2	dedicator of cyto-kinesis 2	0.092
Gbp10	guanylate-binding protein 10	0.088
Il6st	interleukin 6 signal transducer	0.088
Ifnar2	interferon (alpha and beta) receptor 2	0.088
Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.085
Tlr2	toll-like receptor 2	0.083
Ren1	renin 1 structural	0.082
Isg15	ISG15 ubiquitin-like modifier	0.080
Cd86	CD86 antigen	0.078
Cav1	caveolin 1, caveolae protein	0.078
Socs3	suppressor of cytokine signaling 3	0.077
Ccl4	chemokine (C-C motif) ligand 4	0.076
Cd274	CD274 antigen	0.076
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.075
Ccr5	chemokine (C-C motif) receptor 5	0.074
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.074
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.073
Gpr65	G-protein coupled receptor 65	0.068
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.068
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.068
C1ra	complement component 1, r subcomponent A	0.066
Birc3	baculoviral IAP repeat-containing 3	0.064
Fcgr1	Fc receptor, IgG, high affinity I	0.064
Tnf	tumor necrosis factor	0.063
Ifih1	interferon induced with helicase C domain 1	0.059
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.059
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.057
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.057
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.056
H2-D1	histocompatibility 2, D region locus 1	0.054
Irf5	interferon regulatory factor 5	0.053	Mouse
Batf	basic leucine zipper transcription factor, ATF-like	0.052
Ciita	class II transactivator	0.052
C4b	complement component 4B (Childo blood group)	0.050
Unc93b1	unc-93 homolog B1 (C. elegans)	0.049
Hif1a	hypoxia inducible factor 1, alpha subunit	0.047
C2	complement component 2 (within H-2S)	0.046
Myd88	myeloid differentiation primary response gene 88	0.046
Gbp4	guanylate binding protein 4	0.045
Nos3	nitric oxide synthase 3, endothelial cell	0.044	Mouse
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.044
Znfx1	zinc finger, NFX1-type containing 1	0.043
Kit	kit oncogene	0.043
Ldlr	low density lipoprotein receptor	0.043
C1qc	complement component 1, q subcomponent, C chain	0.043
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.042
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.042
H2-Q8	histocompatibility 2, Q region locus 8	0.041
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.040
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.040
Ghr	growth hormone receptor	0.040
Cd40	CD40 antigen	0.039
Fas	Fas (TNF receptor superfamily member 6)	0.038
Lcp2	lymphocyte cytosolic protein 2	0.037
H2-M3	histocompatibility 2, M region locus 3	0.037
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.037
Pdcd1	programmed cell death 1	0.037
Smad3	MAD homolog 3 (Drosophila)	0.036
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.036
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.036
Nckap1l	NCK associated protein 1 like	0.034
Ch25h	cholesterol 25-hydroxylase	0.034
Ifi35	interferon-induced protein 35	0.034
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.033
Aif1	allograft inflammatory factor 1	0.033	Human Rat
Hck	hemopoietic cell kinase	0.033
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.032
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.032
Pnpla2	patatin-like phospholipase domain containing 2	0.031
Gimap4	GTPase, IMAP family member 4	0.031
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.031
Zbp1	Z-DNA binding protein 1	0.031
Sfpi1	SFFV proviral integration 1	0.030
Il1b	interleukin 1 beta	0.030
Vdr	vitamin D receptor	0.030
Fasl	Fas ligand (TNF superfamily, member 6)	0.030
Ifi44	interferon-induced protein 44	0.030
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.029
C3ar1	complement component 3a receptor 1	0.029
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.029
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.028
Bcl3	B-cell leukemia/lymphoma 3	0.028
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.027
Nos1	nitric oxide synthase 1, neuronal	0.027	Mouse
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.027
Apoe	apolipoprotein E	0.026
Mpeg1	macrophage expressed gene 1	0.026
Rel	reticuloendotheliosis oncogene	0.026
Il1a	interleukin 1 alpha	0.026
Itgax	integrin alpha X	0.026
Cd44	CD44 antigen	0.026
Gbp8	guanylate-binding protein 8	0.025
Col14a1	collagen, type XIV, alpha 1	0.025
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.025
Plin1	perilipin 1	0.025
Slamf8	SLAM family member 8	0.024
Sp100	nuclear antigen Sp100	0.024
Gbp9	guanylate-binding protein 9	0.024
Tars	threonyl-tRNA synthetase	0.024
C3	complement component 3	0.024
Jak1	Janus kinase 1	0.024
Slfn1	schlafen 1	0.023
Mx1	myxovirus (influenza virus) resistance 1	0.023
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.023
Nsf	N-ethylmaleimide sensitive fusion protein	0.023
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.022
Vcam1	vascular cell adhesion molecule 1	0.022
Ccr1	chemokine (C-C motif) receptor 1	0.022
Ssb	Sjogren syndrome antigen B	0.022
Ccr7	chemokine (C-C motif) receptor 7	0.022
Ahr	aryl-hydrocarbon receptor	0.022
Ncoa6	nuclear receptor coactivator 6	0.021
Esr2	estrogen receptor 2 (beta)	0.021
Spp1	secreted phosphoprotein 1	0.021
Nmi	N-myc (and STAT) interactor	0.021
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.021
Parp9	poly (ADP-ribose) polymerase family, member 9	0.020
Osmr	oncostatin M receptor	0.020
Drd2	dopamine receptor D2	0.020
Ccl3	chemokine (C-C motif) ligand 3	0.020	Human
Il18r1	interleukin 18 receptor 1	0.020
Aoah	acyloxyacyl hydrolase	0.020
Mmp12	matrix metallopeptidase 12	0.019
Gzmb	granzyme B	0.019
Parp10	poly (ADP-ribose) polymerase family, member 10	0.019
Ar	androgen receptor	0.019
Cd7	CD7 antigen	0.019
Rtp4	receptor transporter protein 4	0.019
H2-Q6	histocompatibility 2, Q region locus 6	0.019
Itgal	integrin alpha L	0.019
Cybb	cytochrome b-245, beta polypeptide	0.019
Parp12	poly (ADP-ribose) polymerase family, member 12	0.019
Flt3l	FMS-like tyrosine kinase 3 ligand	0.019	Mouse
Ythdf2	YTH domain family 2	0.018
Traf1	TNF receptor-associated factor 1	0.018
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.018
Nfil3	nuclear factor, interleukin 3, regulated	0.018
Tbx21	T-box 21	0.018
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.018
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.018
Adar	adenosine deaminase, RNA-specific	0.018
Aim1	absent in melanoma 1	0.017
Arid1b	AT rich interactive domain 1B (SWI-like)	0.017
Cxcl1	chemokine (C-X-C motif) ligand 1	0.017
Tbx2	T-box 2	0.017
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.017
Ccl7	chemokine (C-C motif) ligand 7	0.017
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.017
Nos2	nitric oxide synthase 2, inducible	0.016
Cp	ceruloplasmin	0.016
Ifi203	interferon activated gene 203	0.016
Xcl1	chemokine (C motif) ligand 1	0.016
Crh	corticotropin releasing hormone	0.016
Mmp9	matrix metallopeptidase 9	0.016
Tor3a	torsin family 3, member A	0.016
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.016
Prkd2	protein kinase D2	0.015
Mvp	major vault protein	0.015
Eif3a	eukaryotic translation initiation factor 3, subunit A	0.015
C1qb	complement component 1, q subcomponent, beta polypeptide	0.015
Laptm5	lysosomal-associated protein transmembrane 5	0.015
Msr1	macrophage scavenger receptor 1	0.015
Tapbpl	TAP binding protein-like	0.015
Insr	insulin receptor	0.014
Agtr1a	angiotensin II receptor, type 1a	0.014
Nup62-il4i1	Nup62-Il4i1 protein	0.014
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.014
Il18bp	interleukin 18 binding protein	0.014
Cst7	cystatin F (leukocystatin)	0.014
Lif	leukemia inhibitory factor	0.014
Gzma	granzyme A	0.014
Ctsw	cathepsin W	0.014
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.014
Slc15a3	solute carrier family 15, member 3	0.014
Adcy4	adenylate cyclase 4	0.014
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.014
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.014
Atf4	activating transcription factor 4	0.014
Elf1	E74-like factor 1	0.014
Dnase1l3	deoxyribonuclease 1-like 3	0.014
Chd1	chromodomain helicase DNA binding protein 1	0.014
Notch2	Notch gene homolog 2 (Drosophila)	0.014
Ccl17	chemokine (C-C motif) ligand 17	0.014
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.013
Hnrnpd	heterogeneous nuclear ribonucleoprotein D	0.013
Samhd1	SAM domain and HD domain, 1	0.013
Cebpz	CCAAT/enhancer binding protein zeta	0.013
Herc6	hect domain and RLD 6	0.013
Casp12	caspase 12	0.013
Saa3	serum amyloid A 3	0.013
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.013
Esf1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.013
Ly75	lymphocyte antigen 75	0.013	Mouse
Gata3	GATA binding protein 3	0.013
Il3ra	interleukin 3 receptor, alpha chain	0.013
Mmp3	matrix metallopeptidase 3	0.013
Cd2	CD2 antigen	0.013
Prkcd	protein kinase C, delta	0.013
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.013
Ubd	ubiquitin D	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
H2-T24	histocompatibility 2, T region locus 24	0.012
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.012
Cd3g	CD3 antigen, gamma polypeptide	0.012
Itgb3	integrin beta 3	0.012
Ptgir	prostaglandin I receptor (IP)	0.012
Prpf40a	PRP40 pre-mRNA processing factor 40 homolog A (yeast)	0.012
Itgb2	integrin beta 2	0.012
Tnpo3	transportin 3	0.012
Esr1	estrogen receptor 1 (alpha)	0.012
H2-Q5	histocompatibility 2, Q region locus 5	0.012
Cd180	CD180 antigen	0.012
Sfn	stratifin	0.012
Vegfa	vascular endothelial growth factor A	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.012
Slfn2	schlafen 2	0.012
Lgals9	lectin, galactose binding, soluble 9	0.012
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.012
Fga	fibrinogen alpha chain	0.012
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.012
Pld4	phospholipase D family, member 4	0.011
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.011
Zfx	zinc finger protein X-linked	0.011
Pim1	proviral integration site 1	0.011
Cxcl13	chemokine (C-X-C motif) ligand 13	0.011
Ctss	cathepsin S	0.011
Fpr2	formyl peptide receptor 2	0.011
Foxp3	forkhead box P3	0.011
Lag3	lymphocyte-activation gene 3	0.011
Il2rb	interleukin 2 receptor, beta chain	0.011
Ms4a4d	membrane-spanning 4-domains, subfamily A, member 4D	0.011
Fzd6	frizzled homolog 6 (Drosophila)	0.011
Epsti1	epithelial stromal interaction 1 (breast)	0.011
Fgg	fibrinogen gamma chain	0.011
Vav1	vav 1 oncogene	0.011
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.011
Itga4	integrin alpha 4	0.011
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.011
Sod3	superoxide dismutase 3, extracellular	0.011
BC006779	cDNA sequence BC006779	0.011
Selplg	selectin, platelet (p-selectin) ligand	0.011
Il18rap	interleukin 18 receptor accessory protein	0.011
Gp49a	glycoprotein 49 A	0.011
Ocln	occludin	0.011
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.011
Il1rn	interleukin 1 receptor antagonist	0.011
N4bp1	NEDD4 binding protein 1	0.011
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.011
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.011
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.011
Atf1	activating transcription factor 1	0.010
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.010
Has1	hyaluronan synthase1	0.010
Ccl22	chemokine (C-C motif) ligand 22	0.010
Sh2d2a	SH2 domain protein 2A	0.010
Eif5b	eukaryotic translation initiation factor 5B	0.010
Itk	IL2-inducible T-cell kinase	0.010