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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cyclin dependent protein serine threonine kinase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cyclin dependent protein serine threonine kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	0.996
Rb1	retinoblastoma 1	0.996
Apc	adenomatosis polyposis coli	0.996	Human
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.995
Hif1a	hypoxia inducible factor 1, alpha subunit	0.918
Jun	Jun oncogene	0.880
Brca1	breast cancer 1	0.856
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.840	Mouse
Cdk6	cyclin-dependent kinase 6	0.781
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.761	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.758
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.732
Casp1	caspase 1	0.730	Mouse
Brca2	breast cancer 2	0.704
Cdk1	cyclin-dependent kinase 1	0.688
Nf1	neurofibromatosis 1	0.657
E2f1	E2F transcription factor 1	0.591
Pkd1	polycystic kidney disease 1 homolog	0.588	Human
Cdk4	cyclin-dependent kinase 4	0.586
Prc1	protein regulator of cytokinesis 1	0.583
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.560	Human
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.559
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.553
Vhl	von Hippel-Lindau tumor suppressor	0.520
Ccna2	cyclin A2	0.488
Esr1	estrogen receptor 1 (alpha)	0.453
Ccnd1	cyclin D1	0.420	Human
Fos	FBJ osteosarcoma oncogene	0.409	Fly
Ccnb1	cyclin B1	0.402	Yeast
Egr1	early growth response 1	0.396
Pten	phosphatase and tensin homolog	0.375	Human
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.371	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.363
Zfp36	zinc finger protein 36	0.356
Atf3	activating transcription factor 3	0.345	Fly
Mdm2	transformed mouse 3T3 cell double minute 2	0.344
Msh2	mutS homolog 2 (E. coli)	0.337
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.308
Ccnf	cyclin F	0.302
Cdkn3	cyclin-dependent kinase inhibitor 3	0.299
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.271
Braf	Braf transforming gene	0.265
Ptgs2	prostaglandin-endoperoxide synthase 2	0.265
Thbs1	thrombospondin 1	0.265
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.250
Il18	interleukin 18	0.232
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.221
Tlr4	toll-like receptor 4	0.197
Gbp5	guanylate binding protein 5	0.186
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.181
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.180	Mouse
Kif4	kinesin family member 4	0.179
Smad2	MAD homolog 2 (Drosophila)	0.170
Lrrk2	leucine-rich repeat kinase 2	0.170
Cdk2	cyclin-dependent kinase 2	0.164
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.155
Ckap2	cytoskeleton associated protein 2	0.154
Kif20a	kinesin family member 20A	0.151
Nf2	neurofibromatosis 2	0.150
Pycard	PYD and CARD domain containing	0.144
Aurka	aurora kinase A	0.141
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.140
Ahr	aryl-hydrocarbon receptor	0.139
Prkce	protein kinase C, epsilon	0.136
Hes1	hairy and enhancer of split 1 (Drosophila)	0.136
Notch1	Notch gene homolog 1 (Drosophila)	0.135
Nos3	nitric oxide synthase 3, endothelial cell	0.134
Cyld	cylindromatosis (turban tumor syndrome)	0.122
Mis18bp1	MIS18 binding protein 1	0.115
Kitl	kit ligand	0.114
Hbegf	heparin-binding EGF-like growth factor	0.113
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.106
Ptk2	PTK2 protein tyrosine kinase 2	0.106
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.102
Kif2c	kinesin family member 2C	0.102
Fam64a	family with sequence similarity 64, member A	0.101
Mdm4	transformed mouse 3T3 cell double minute 4	0.100
Stk11	serine/threonine kinase 11	0.098
Foxo3	forkhead box O3	0.097
Plk1	polo-like kinase 1 (Drosophila)	0.097	Human
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.094
Rbl1	retinoblastoma-like 1 (p107)	0.092
Trp63	transformation related protein 63	0.091
Gsk3b	glycogen synthase kinase 3 beta	0.090
Tsc1	tuberous sclerosis 1	0.089
Cyr61	cysteine rich protein 61	0.081
Xpa	xeroderma pigmentosum, complementation group A	0.081
Ghr	growth hormone receptor	0.079
Runx1	runt related transcription factor 1	0.079
Gata4	GATA binding protein 4	0.076
Aurkb	aurora kinase B	0.076
Klf4	Kruppel-like factor 4 (gut)	0.076
Cdca8	cell division cycle associated 8	0.075
Meox2	mesenchyme homeobox 2	0.071
Sav1	salvador homolog 1 (Drosophila)	0.070
Ube2c	ubiquitin-conjugating enzyme E2C	0.069
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.067
Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)	0.066
Birc5	baculoviral IAP repeat-containing 5	0.066
Psen1	presenilin 1	0.064
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.064
Efnb2	ephrin B2	0.063
Tmpo	thymopoietin	0.061
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.059
Skil	SKI-like	0.058
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.056
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.056
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.055
Spnb2	spectrin beta 2	0.054
Casp3	caspase 3	0.054
Il6st	interleukin 6 signal transducer	0.053
Dusp1	dual specificity phosphatase 1	0.052
Axin1	axin 1	0.052
Csrp2bp	cysteine and glycine-rich protein 2 binding protein	0.052
Anln	anillin, actin binding protein	0.052
Nfil3	nuclear factor, interleukin 3, regulated	0.052
Cenpa	centromere protein A	0.051
Egr2	early growth response 2	0.051
Smad4	MAD homolog 4 (Drosophila)	0.051
Iqgap3	IQ motif containing GTPase activating protein 3	0.050
Racgap1	Rac GTPase-activating protein 1	0.047
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.046
Ccnb2	cyclin B2	0.046	Yeast
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.045
Kif11	kinesin family member 11	0.045
Ptch1	patched homolog 1	0.044
Fosl2	fos-like antigen 2	0.044	Fly
Tsc2	tuberous sclerosis 2	0.043
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.043
Top2a	topoisomerase (DNA) II alpha	0.043
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.043
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.042
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.042
Ttk	Ttk protein kinase	0.040
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.040
Csf1	colony stimulating factor 1 (macrophage)	0.040
Plk4	polo-like kinase 4 (Drosophila)	0.039
Ccnd3	cyclin D3	0.038	Human
Lmnb1	lamin B1	0.038
Junb	Jun-B oncogene	0.037
Bcl2	B-cell leukemia/lymphoma 2	0.037
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.036
Kit	kit oncogene	0.036
Pim3	proviral integration site 3	0.035
Cdk14	cyclin-dependent kinase 14	0.035
Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)	0.034
Cnbp	cellular nucleic acid binding protein	0.034
Cd44	CD44 antigen	0.034
Ctnnd1	catenin (cadherin associated protein), delta 1	0.034
Dtl	denticleless homolog (Drosophila)	0.034
Nbn	nibrin	0.033
Apoe	apolipoprotein E	0.033
Nras	neuroblastoma ras oncogene	0.033
Stk4	serine/threonine kinase 4	0.032
Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)	0.032
Rel	reticuloendotheliosis oncogene	0.032
Wls	wntless homolog (Drosophila)	0.032
Ect2	ect2 oncogene	0.031
E2f8	E2F transcription factor 8	0.031
Raf1	v-raf-leukemia viral oncogene 1	0.031
Jak2	Janus kinase 2	0.031
Ncaph	non-SMC condensin I complex, subunit H	0.031
Aim2	absent in melanoma 2	0.031
Kif23	kinesin family member 23	0.031
Nmi	N-myc (and STAT) interactor	0.031
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.030	Human
Spag5	sperm associated antigen 5	0.030
Plaur	plasminogen activator, urokinase receptor	0.030
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.030
Nusap1	nucleolar and spindle associated protein 1	0.029
Cenpk	centromere protein K	0.029
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.028
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.028
Foxm1	forkhead box M1	0.028
Apaf1	apoptotic peptidase activating factor 1	0.028
Cxcl1	chemokine (C-X-C motif) ligand 1	0.028
Hr	hairless	0.027
Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.027
Ar	androgen receptor	0.027
Cd14	CD14 antigen	0.027
Btg2	B-cell translocation gene 2, anti-proliferative	0.027
Fadd	Fas (TNFRSF6)-associated via death domain	0.026
Gbp7	guanylate binding protein 7	0.026
Mks1	Meckel syndrome, type 1	0.026
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.026
Socs3	suppressor of cytokine signaling 3	0.026
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.025
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.025
Cdca7l	cell division cycle associated 7 like	0.025
Pvr	poliovirus receptor	0.025
Atf4	activating transcription factor 4	0.024
Pparg	peroxisome proliferator activated receptor gamma	0.024
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.024
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.024
Irs2	insulin receptor substrate 2	0.024
Rpgrip1l	Rpgrip1-like	0.023
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.023
Cnn3	calponin 3, acidic	0.023
Rad51ap1	RAD51 associated protein 1	0.023
Krt14	keratin 14	0.022
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.022
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.022
Smad5	MAD homolog 5 (Drosophila)	0.021
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.021
Fam83h	family with sequence similarity 83, member H	0.021
Lyz2	lysozyme 2	0.021
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.021
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.021
Trp73	transformation related protein 73	0.020
Itga3	integrin alpha 3	0.020
Arhgap1	Rho GTPase activating protein 1	0.020
Bhlhe40	basic helix-loop-helix family, member e40	0.020
Foxa2	forkhead box A2	0.020
Melk	maternal embryonic leucine zipper kinase	0.020
Stat3	signal transducer and activator of transcription 3	0.020
Rxra	retinoid X receptor alpha	0.020
Cetn3	centrin 3	0.019
Slc7a1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	0.019
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.018
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.018
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.018
Purb	purine rich element binding protein B	0.018
Egfr	epidermal growth factor receptor	0.018
Tcf4	transcription factor 4	0.018
Akt2	thymoma viral proto-oncogene 2	0.018
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.018
Gbp3	guanylate binding protein 3	0.018
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.018
Mybl2	myeloblastosis oncogene-like 2	0.018
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.017
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.017
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.017
Arl1	ADP-ribosylation factor-like 1	0.017
Ret	ret proto-oncogene	0.017
Foxo1	forkhead box O1	0.017
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.017
Dctn1	dynactin 1	0.017
Ptp4a2	protein tyrosine phosphatase 4a2	0.017
Wwox	WW domain-containing oxidoreductase	0.017
Rhob	ras homolog gene family, member B	0.017
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.016
Pxn	paxillin	0.016
Myc	myelocytomatosis oncogene	0.016
Mki67	antigen identified by monoclonal antibody Ki 67	0.016
Sprr1a	small proline-rich protein 1A	0.016
Pim2	proviral integration site 2	0.016
Hspa1b	heat shock protein 1B	0.016
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.016	Mouse
Mapk14	mitogen-activated protein kinase 14	0.015
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.015
Cys1	cystin 1	0.015
Tcf19	transcription factor 19	0.015
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.015
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.015
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.015
Pofut1	protein O-fucosyltransferase 1	0.015
Stxbp1	syntaxin binding protein 1	0.015
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.015
E2f3	E2F transcription factor 3	0.015
Fas	Fas (TNF receptor superfamily member 6)	0.015
Il1b	interleukin 1 beta	0.015
Arpc4	actin related protein 2/3 complex, subunit 4	0.014
Smad1	MAD homolog 1 (Drosophila)	0.014
Pkd2	polycystic kidney disease 2	0.014	Human
Casp7	caspase 7	0.014	Mouse
Klf5	Kruppel-like factor 5	0.014
Thrb	thyroid hormone receptor beta	0.014
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.014
Bicc1	bicaudal C homolog 1 (Drosophila)	0.014
Pbk	PDZ binding kinase	0.014
Hspa1a	heat shock protein 1A	0.014
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.014
Sgpl1	sphingosine phosphate lyase 1	0.014
Kiss1	KiSS-1 metastasis-suppressor	0.014
Irs1	insulin receptor substrate 1	0.014
Nab2	Ngfi-A binding protein 2	0.014
Htt	huntingtin	0.014
Kif22	kinesin family member 22	0.013
Trim3	tripartite motif-containing 3	0.013
Ccdc99	coiled-coil domain containing 99	0.013
Id2	inhibitor of DNA binding 2	0.013
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.013
Yap1	yes-associated protein 1	0.013
Hspa8	heat shock protein 8	0.013
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.013
Ripk3	receptor-interacting serine-threonine kinase 3	0.013
Traf2	TNF receptor-associated factor 2	0.013
Tada3	transcriptional adaptor 3	0.013
Men1	multiple endocrine neoplasia 1	0.013	Human
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.013
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.013
Rbl2	retinoblastoma-like 2	0.013
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.013
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.013
Tgfb1	transforming growth factor, beta 1	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.013
Adat3	adenosine deaminase, tRNA-specific 3, TAD2 homolog (S. cerevisiae)	0.012
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.012
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.012
Clock	circadian locomotor output cycles kaput	0.012
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Traf6	TNF receptor-associated factor 6	0.012
Tada2a	transcriptional adaptor 2A	0.012
Trib3	tribbles homolog 3 (Drosophila)	0.012
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.012
Vav2	vav 2 oncogene	0.012
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.012
Ripk4	receptor-interacting serine-threonine kinase 4	0.012
1190002N15Rik	RIKEN cDNA 1190002N15 gene	0.012
Bad	BCL2-associated agonist of cell death	0.012
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.012
Fstl3	follistatin-like 3	0.012
Usp21	ubiquitin specific peptidase 21	0.012
Flot2	flotillin 2	0.012
Diap3	diaphanous homolog 3 (Drosophila)	0.012
Git1	G protein-coupled receptor kinase-interactor 1	0.012
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.012
Phf1	PHD finger protein 1	0.011
Arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1	0.011
Sox17	SRY-box containing gene 17	0.011
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.011
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Gtse1	G two S phase expressed protein 1	0.011
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.011	Human Mouse
Sufu	suppressor of fused homolog (Drosophila)	0.011
Socs1	suppressor of cytokine signaling 1	0.011
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.011
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.011
Sykb	spleen tyrosine kinase	0.011
Pygo2	pygopus 2	0.011
Mprip	myosin phosphatase Rho interacting protein	0.011
Tmod3	tropomodulin 3	0.011
Pthlh	parathyroid hormone-like peptide	0.011
Wwc2	WW, C2 and coiled-coil domain containing 2	0.011
Eid1	EP300 interacting inhibitor of differentiation 1	0.011
Rfwd2	ring finger and WD repeat domain 2	0.011
Ptf1a	pancreas specific transcription factor, 1a	0.010
Haus4	HAUS augmin-like complex, subunit 4	0.010
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.010
Mdfic	MyoD family inhibitor domain containing	0.010
Rora	RAR-related orphan receptor alpha	0.010
Lrrc8c	leucine rich repeat containing 8 family, member C	0.010
Foxp1	forkhead box P1	0.010
Wdr5	WD repeat domain 5	0.010
Eapp	E2F-associated phosphoprotein	0.010
Mbtps1	membrane-bound transcription factor peptidase, site 1	0.010