The network for 'extrinsic apoptotic signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

extrinsic apoptotic signaling pathway

A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.

Mus musculus
Name Description Probability Func Analog Organism
Col1a1 collagen, type I, alpha 1 1.000
Tnf tumor necrosis factor 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Trp53 transformation related protein 53 0.999
Mdm2 transformed mouse 3T3 cell double minute 2 0.998
Fas Fas (TNF receptor superfamily member 6) 0.998
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.998
Pten phosphatase and tensin homolog 0.997
Ikzf1 IKAROS family zinc finger 1 0.996
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.995
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.994
Bcl2 B-cell leukemia/lymphoma 2 0.986
Egfr epidermal growth factor receptor 0.982
Ifng interferon gamma 0.979
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.978
Tgfb1 transforming growth factor, beta 1 0.977
Csf1 colony stimulating factor 1 (macrophage) 0.976
Itgal integrin alpha L 0.975
Ptgs2 prostaglandin-endoperoxide synthase 2 0.973
Tgfbr2 transforming growth factor, beta receptor II 0.973
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.972
Cd44 CD44 antigen 0.971
Nos2 nitric oxide synthase 2, inducible 0.966
Lyz2 lysozyme 2 0.960
Vegfa vascular endothelial growth factor A 0.959
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.951
Il2rg interleukin 2 receptor, gamma chain 0.944
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.944
Cd40 CD40 antigen 0.933
Efnb2 ephrin B2 0.933
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.928
Esr1 estrogen receptor 1 (alpha) 0.923
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.923
Adam17 a disintegrin and metallopeptidase domain 17 0.919
Cd19 CD19 antigen 0.918
Mmp9 matrix metallopeptidase 9 0.918
Il10 interleukin 10 0.917
Thbs1 thrombospondin 1 0.906
Sfrp2 secreted frizzled-related protein 2 0.903
Nos3 nitric oxide synthase 3, endothelial cell 0.903
Psen1 presenilin 1 0.902
Fbn1 fibrillin 1 0.901
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.893
Ret ret proto-oncogene 0.889
Igh immunoglobulin heavy chain complex 0.886
Bax BCL2-associated X protein 0.879
Traf2 TNF receptor-associated factor 2 0.867
Nlrp3 NLR family, pyrin domain containing 3 0.865
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.856
Gpr132 G protein-coupled receptor 132 0.855
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.855
Lta lymphotoxin A 0.854
Apc adenomatosis polyposis coli 0.849
Lepr leptin receptor 0.836
Inpp5d inositol polyphosphate-5-phosphatase D 0.834
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.833
Hr hairless 0.832
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.828
Sharpin SHANK-associated RH domain interacting protein 0.825
Ptk2 PTK2 protein tyrosine kinase 2 0.813
Il2rb interleukin 2 receptor, beta chain 0.811
Lck lymphocyte protein tyrosine kinase 0.801
Ccr1 chemokine (C-C motif) receptor 1 0.799
Smad3 MAD homolog 3 (Drosophila) 0.786
Rxra retinoid X receptor alpha 0.785
Pax2 paired box gene 2 0.778
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.777
Rb1 retinoblastoma 1 0.775
Kit kit oncogene 0.770
Il4 interleukin 4 0.770
Ncoa3 nuclear receptor coactivator 3 0.762
Icos inducible T-cell co-stimulator 0.757
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.745
Notch1 Notch gene homolog 1 (Drosophila) 0.743
Krt5 keratin 5 0.732
Selp selectin, platelet 0.731
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.730
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.725
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.724
Fgf7 fibroblast growth factor 7 0.715
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.710
Lmna lamin A 0.706
Nf1 neurofibromatosis 1 0.702
Src Rous sarcoma oncogene 0.698
Itch itchy, E3 ubiquitin protein ligase 0.694
Pdcd1 programmed cell death 1 0.693
Hoxa11 homeobox A11 0.692
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.687
Fst follistatin 0.684
Tcra T-cell receptor alpha chain 0.683
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.674
Mcl1 myeloid cell leukemia sequence 1 0.670
Yap1 yes-associated protein 1 0.665
Fasl Fas ligand (TNF superfamily, member 6) 0.656
Braf Braf transforming gene 0.645
Ltb lymphotoxin B 0.636
Mmp2 matrix metallopeptidase 2 0.636
Hif1a hypoxia inducible factor 1, alpha subunit 0.634
Fgfr2 fibroblast growth factor receptor 2 0.634
Col1a2 collagen, type I, alpha 2 0.629
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
bcl2l1 bcl2-like 1 0.826
nf1a neurofibromin 1a 0.717
cav1 caveolin 1 0.669
igf1rb insulin-like growth factor 1b receptor 0.664
osr1 odd-skipped related 1 (Drosophila) 0.615
tgfb3 transforming growth factor, beta 3 0.611
brd4 bromodomain containing 4 0.597
epas1b endothelial PAS domain protein 1b 0.572
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.558
fzd7b frizzled homolog 7b 0.519
mapk6 mitogen-activated protein kinase 6 0.495
ptgs1 prostaglandin-endoperoxide synthase 1 0.487
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.477
tagln2 transgelin 2 0.475
kita kit receptor a 0.421
epha4a eph receptor A4a 0.405
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.386
ifnphi1 interferon phi 1 0.381
ptgds prostaglandin D2 synthase 0.378
mmp9 matrix metalloproteinase 9 0.366
nrg2a neuregulin 2a 0.353
krt4 keratin 4 0.352
baxa bcl2-associated X protein, a 0.347
stc1l stanniocalcin 1, like 0.344
hmgb1b high-mobility group box 1b 0.343
pax7b paired box gene 7b 0.334
met met proto-oncogene (hepatocyte growth factor receptor) 0.315
pcdh18b protocadherin 18b 0.311
rxrbb retinoid x receptor, beta b 0.304
mdm2 transformed 3T3 cell double minute 2 homolog (mouse) 0.303
fgfr3 fibroblast growth factor receptor 3 0.301
ntn2 netrin 2 0.296
sema3aa semaphorin 3aa 0.294
notch2 notch homolog 2 0.290
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.286
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.284
eya1 eyes absent homolog 1 0.278
ryk receptor-like tyrosine kinase 0.276
tgfb2 transforming growth factor, beta 2 0.274
hbbe1.1 hemoglobin beta embryonic-1.1 0.271
dlx4a distal-less homeobox gene 4a 0.266
ldb1a LIM-domain binding factor 1a 0.265
il6st interleukin 6 signal transducer 0.262
igf1 insulin-like growth factor 1 0.256
lef1 lymphocyte enhancer binding factor 1 0.253
cmyb transcription factor cmyb 0.250
rarga retinoic acid receptor gamma a 0.249
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.248
ripk2 receptor-interacting serine-threonine kinase 2 0.247
hmx2 H6 family homeobox 2 0.246
jup junction plakoglobin 0.244
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.233
prkcea protein kinase C, epsilon a 0.233
ptgs2a prostaglandin-endoperoxide synthase 2a 0.227
bmp2b bone morphogenetic protein 2b 0.227
igf1ra insulin-like growth factor 1a receptor 0.226
mcl1a myeloid cell leukemia sequence 1a 0.221
sb:cb166 sb:cb166 0.219
acvr2a activin receptor IIa 0.216
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.216
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.212
metrnl meteorin, glial cell differentiation regulator-like 0.211
dct dopachrome tautomerase 0.209
anxa1a annexin A1a 0.209
slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 0.208
lhx2b LIM homeobox 2b 0.205
il6r interleukin 6 receptor 0.203
neo1 neogenin 1 0.201
cdkn1a cyclin-dependent kinase inhibitor 1A 0.201
ptp4a3 protein tyrosine phosphatase type IVA, member 3 0.201
sgk1 serum/glucocorticoid regulated kinase 1 0.195
tfec transcription factor EC 0.194
lcp1 lymphocyte cytosolic plastin 1 0.192
twist2 twist2 0.185
apom apolipoprotein M 0.183
krt8 keratin 8 0.173
plekhg5a pleckstrin homology domain containing, family G (with RhoGef domain) member 5a 0.172
gh1 growth hormone 1 0.171
cnn2 calponin 2 0.171
crestin crestin 0.171
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.170
she Src homology 2 domain containing E 0.167
arpc1b actin related protein 2/3 complex, subunit 1B 0.166
phox2b paired-like homeobox 2b 0.164
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.164
wnt3 wingless-type MMTV integration site family, member 3 0.164
sox10 SRY-box containing gene 10 0.163
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.161
fadd Fas (tnfrsf6)-associated via death domain 0.160
cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 0.160
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.160
notch3 notch homolog 3 0.160
mpx myeloid-specific peroxidase 0.159
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.159
rag1 recombination activating gene 1 0.159
dip2c DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.156
plg plasminogen 0.155
zgc:162126 zgc:162126 0.155
tlr3 toll-like receptor 3 0.154
hoxd4a homeo box D4a 0.153
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Drosophila melanogaster
Name Description Probability Func Analog Organism
NetB Netrin-B 0.723
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.607
Rel Relish 0.397
babo baboon 0.243
fz2 frizzled 2 0.228
tkv thickveins 0.221
Toll-6 CG7250 gene product from transcript CG7250-RA 0.193
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.190
Akt1 CG4006 gene product from transcript CG4006-RA 0.184
Toll-7 CG8595 gene product from transcript CG8595-RA 0.182
EcR Ecdysone receptor 0.181
Ras85D Ras oncogene at 85D 0.175
Smox Smad on X 0.163
fng fringe 0.161
p53 CG33336 gene product from transcript CG33336-RB 0.161
Nrx-IV Neurexin IV 0.140
18w 18 wheeler 0.134
Kr Kruppel 0.130
stumps CG31317 gene product from transcript CG31317-RC 0.129
eya eyes absent 0.124
Tl Toll 0.121
rut rutabaga 0.118
ash2 absent, small, or homeotic discs 2 0.116
jing CG9397 gene product from transcript CG9397-RI 0.116
chico CG5686 gene product from transcript CG5686-RB 0.114
myoglianin CG1838 gene product from transcript CG1838-RD 0.114
ftz-f1 ftz transcription factor 1 0.110
trio CG18214 gene product from transcript CG18214-RA 0.107
sd scalloped 0.106
CaMKII Calcium/calmodulin-dependent protein kinase II 0.101
wg wingless 0.097
Nrg Neuroglian 0.096
Lasp CG3849 gene product from transcript CG3849-RB 0.094
InR Insulin-like receptor 0.092
Atg1 Autophagy-specific gene 1 0.090
Cdk5alpha Cdk5 activator-like protein 0.089
rst roughest 0.087
egr eiger 0.087
Src42A Src oncogene at 42A 0.083
zfh1 Zn finger homeodomain 1 0.080
sr stripe 0.079
fkh fork head 0.079
Smg5 CG8954 gene product from transcript CG8954-RA 0.079
wb wing blister 0.077
mew multiple edematous wings 0.077
conv convoluted 0.076
Hs6st Heparan sulfate 6-O-sulfotransferase 0.075
neuroligin CG13772 gene product from transcript CG13772-RA 0.075
twi twist 0.074
kibra kibra ortholog 0.073
rpr reaper 0.072
dm diminutive 0.071
Plc21C Phospholipase C at 21C 0.071
wun wunen 0.071
kis kismet 0.071
CadN Cadherin-N 0.070
plexA plexin A 0.070
Pten CG5671 gene product from transcript CG5671-RB 0.070
Adar Adenosine deaminase acting on RNA 0.069
Grip Glutamate receptor binding protein 0.069
Myd88 CG2078 gene product from transcript CG2078-RA 0.069
Pvr PDGF- and VEGF-receptor related 0.068
Tao-1 CG14217 gene product from transcript CG14217-RF 0.067
Thor CG8846 gene product from transcript CG8846-RA 0.067
Mical Molecule interacting with CasL 0.067
Sema-1a CG18405 gene product from transcript CG18405-RD 0.066
form3 formin 3 0.066
msn misshapen 0.066
gcm glial cells missing 0.065
LIMK1 LIM-kinase1 0.064
Unc-76 CG3981 gene product from transcript CG3981-RB 0.064
Pde8 Phosphodiesterase 8 0.064
Dcp-1 Death caspase-1 0.064
hkb huckebein 0.063
spi spitz 0.062
if inflated 0.062
Dfd Deformed 0.062
Pk61C Protein kinase 61C 0.061
cora coracle 0.060
DAAM Dishevelled Associated Activator of Morphogenesis 0.060
Wnt5 Wnt oncogene analog 5 0.060
th thread 0.059
Tig Tiggrin 0.059
Pka-C1 cAMP-dependent protein kinase 1 0.058
tefu telomere fusion 0.058
G-salpha60A G protein salpha 60A 0.057
dpp decapentaplegic 0.057
aop anterior open 0.056
Traf4 TNF-receptor-associated factor 4 0.056
drl derailed 0.055
dve defective proventriculus 0.054
Tollo CG6890 gene product from transcript CG6890-RA 0.054
LanA Laminin A 0.053
fas faint sausage 0.053
drpr draper 0.052
oys oysgedart 0.052
Rya-r44F Ryanodine receptor 44F 0.052
Sdc Syndecan 0.052
klar klarsicht 0.051
ex expanded 0.051
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Homo sapiens
Name Description Probability Func Analog Organism
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.000
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
BCL2L1 BCL2-like 1 0.999
TRAF2 TNF receptor-associated factor 2 0.998
BIRC3 baculoviral IAP repeat containing 3 0.998
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.998
CFLAR CASP8 and FADD-like apoptosis regulator 0.997
BCL2 B-cell CLL/lymphoma 2 0.996
BIRC2 baculoviral IAP repeat containing 2 0.996
XIAP X-linked inhibitor of apoptosis 0.995
TRAF1 TNF receptor-associated factor 1 0.995
TRAF3 TNF receptor-associated factor 3 0.994
TRADD TNFRSF1A-associated via death domain 0.993
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.991
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.984
FAS Fas (TNF receptor superfamily, member 6) 0.983
FADD Fas (TNFRSF6)-associated via death domain 0.983
FHL2 four and a half LIM domains 2 0.979
SMAD2 SMAD family member 2 0.972
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.953
BAX BCL2-associated X protein 0.953
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.950
EGFR epidermal growth factor receptor 0.947
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.938
RNF11 ring finger protein 11 0.932
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.930
RIPK2 receptor-interacting serine-threonine kinase 2 0.927
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.914
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.903
STK4 serine/threonine kinase 4 0.890
SMAD3 SMAD family member 3 0.885
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.880
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.877
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.871
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.870
AR androgen receptor 0.869
UBC ubiquitin C 0.850
TRAF5 TNF receptor-associated factor 5 0.840
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.822
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.800
SQSTM1 sequestosome 1 0.799
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.796
PML promyelocytic leukemia 0.793
TAL1 T-cell acute lymphocytic leukemia 1 0.786
FLNA filamin A, alpha 0.783
BAD BCL2-associated agonist of cell death 0.783
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.759
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.756
TNF tumor necrosis factor 0.751
SMAD7 SMAD family member 7 0.751
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.739
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.734
TRAF6 TNF receptor-associated factor 6 0.726
IL4R interleukin 4 receptor 0.705
BID BH3 interacting domain death agonist 0.700
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.696
TGFB1 transforming growth factor, beta 1 0.666
VEGFA vascular endothelial growth factor A 0.665
NRP1 neuropilin 1 0.661
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.657
BMP2 bone morphogenetic protein 2 0.654
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.639
ENG endoglin 0.637
HCK hemopoietic cell kinase 0.634
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.630
IL8 interleukin 8 0.608
SMAD4 SMAD family member 4 0.590
CAV1 caveolin 1, caveolae protein, 22kDa 0.586
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.585
SMAD1 SMAD family member 1 0.584
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.584
FGF1 fibroblast growth factor 1 (acidic) 0.573
MAPK1 mitogen-activated protein kinase 1 0.572
FGA fibrinogen alpha chain 0.556
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.542
TANK TRAF family member-associated NFKB activator 0.536
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.534
BTRC beta-transducin repeat containing 0.532
TP53BP2 tumor protein p53 binding protein, 2 0.529
CXCL2 chemokine (C-X-C motif) ligand 2 0.517
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.504
NLRC4 NLR family, CARD domain containing 4 0.502
SOCS3 suppressor of cytokine signaling 3 0.499
PLAU plasminogen activator, urokinase 0.499
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.498
CD40 CD40 molecule, TNF receptor superfamily member 5 0.496
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.495
TGFBR1 transforming growth factor, beta receptor 1 0.493
APP amyloid beta (A4) precursor protein 0.483
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.452
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.449
PLAUR plasminogen activator, urokinase receptor 0.445
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.444
FN1 fibronectin 1 0.442
GRB2 growth factor receptor-bound protein 2 0.441
ZMYND11 zinc finger, MYND-type containing 11 0.438
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.435
SKIL SKI-like oncogene 0.422
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.421
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Rattus norvegicus
Name Description Probability Func Analog Organism
Smad7 SMAD family member 7 0.135
Arpc1b actin related protein 2/3 complex, subunit 1B 0.114
Cd86 CD86 molecule 0.102
Smad1 SMAD family member 1 0.083
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.081
Hpx hemopexin 0.076
Sirpa signal-regulatory protein alpha 0.066
Vat1 vesicle amine transport protein 1 homolog (T californica) 0.063
Met met proto-oncogene 0.043
Mprip myosin phosphatase Rho interacting protein 0.038
Lepr leptin receptor 0.036
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.036
Gja5 gap junction protein, alpha 5 0.032
Adora2a adenosine A2a receptor 0.031
Lrp10 low-density lipoprotein receptor-related protein 10 0.031
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.030
Fgfr2 fibroblast growth factor receptor 2 0.029
Fgfr1 Fibroblast growth factor receptor 1 0.029
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.029
Adrbk1 adrenergic, beta, receptor kinase 1 0.027
Hck hemopoietic cell kinase 0.026
Taok1 TAO kinase 1 0.024
Flt1 FMS-related tyrosine kinase 1 0.024
Glg1 golgi apparatus protein 1 0.023
Hspb1 heat shock protein 1 0.022
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.022
Myh9 myosin, heavy chain 9, non-muscle 0.021
Unc5b unc-5 homolog B (C. elegans) 0.021
Il1a interleukin 1 alpha 0.021
Map3k3 mitogen activated protein kinase kinase kinase 3 0.021
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.020
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.020
Il4ra interleukin 4 receptor, alpha 0.020
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.019
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.019
Ddr1 discoidin domain receptor tyrosine kinase 1 0.018
Zyx zyxin 0.018
Ptgfr prostaglandin F receptor 0.018
Mtch1 mitochondrial carrier homolog 1 (C. elegans) 0.018
Ralgds ral guanine nucleotide dissociation stimulator 0.018
Gstm1 glutathione S-transferase mu 1 0.018
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.017
Prkcd protein kinase C, delta 0.017
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.017
Ccdc102a coiled-coil domain containing 102A 0.017
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.017
Ccl3 chemokine (C-C motif) ligand 3 0.017
Fgb fibrinogen beta chain 0.016
C4bpa complement component 4 binding protein, alpha 0.016
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.016
Ptafr platelet-activating factor receptor 0.016
Epn2 epsin 2 0.015
Gpr20 G protein-coupled receptor 20 0.015
Il13ra1 interleukin 13 receptor, alpha 1 0.015
Cd44 Cd44 molecule 0.015
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.015
Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.015
Grm5 glutamate receptor, metabotropic 5 0.015
Cd14 CD14 molecule 0.015
Cd99 CD99 antigen 0.014
Tcf4 transcription factor 4 0.014
Plec plectin 0.014
Rara retinoic acid receptor, alpha 0.014
Chrng cholinergic receptor, nicotinic, gamma 0.014
Rxra retinoid X receptor alpha 0.014
Mcm6 minichromosome maintenance complex component 6 0.013
Ece1 endothelin converting enzyme 1 0.013
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.013
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.013
Fgg fibrinogen gamma chain 0.013
Smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.013
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.013
Orai1 ORAI calcium release-activated calcium modulator 1 0.013
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.013
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.013
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.013
Il7 interleukin 7 0.013
Epn1 Epsin 1 0.012
Trhr2 thyrotropin releasing hormone receptor 2 0.012
Cd80 Cd80 molecule 0.012
Gata3 GATA binding protein 3 0.012
Lcn2 lipocalin 2 0.012
Casp3 caspase 3 0.012
Olr1701 olfactory receptor 1701 0.012
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.012
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.012
Anxa2 annexin A2 0.011
Cast calpastatin 0.011
Ptprs protein tyrosine phosphatase, receptor type, S 0.011
Tcrb T-cell receptor beta chain 0.011
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.011
Slc35b1 solute carrier family 35, member B1 0.011
Csnk1g3 casein kinase 1, gamma 3 0.011
Casp2 caspase 2 0.011
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.011
Gata6 GATA binding protein 6 0.011
Kng1 kininogen 1 0.011
Fyn FYN oncogene related to SRC, FGR, YES 0.010
Pdia6 protein disulfide isomerase family A, member 6 0.010
Il2rb interleukin 2 receptor, beta 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism