IMP

Process View

Drosophila melanogaster

28 genes annotated in fly

Multi-species View

negative regulation of wnt signaling pathway

GO:0030178

Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in fly Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of wnt signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of wnt signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
smo	smoothened	0.954
wg	wingless	0.940
hep	hemipterous	0.931
ci	cubitus interruptus	0.796	Human
dsh	dishevelled	0.757
Akt1	CG4006 gene product from transcript CG4006-RA	0.748
ds	dachsous	0.699
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.660
ex	expanded	0.660
tsh	teashirt	0.615
dm	diminutive	0.505
hh	hedgehog	0.503	Mouse
nkd	naked cuticle	0.499
wts	warts	0.483
dally	division abnormally delayed	0.453	Mouse Fly
EcR	Ecdysone receptor	0.412
aop	anterior open	0.411
sd	scalloped	0.398
pan	pangolin	0.380	Human Zebrafish
gro	groucho	0.320
hipk	homeodomain interacting protein kinase	0.273
dlp	dally-like	0.256
cos	costa	0.253
fz	frizzled	0.238
stg	string	0.238
bsk	basket	0.220
tkv	thickveins	0.216
Zyx102EF	CG32018 gene product from transcript CG32018-RA	0.212
Egfr	Epidermal growth factor receptor	0.204
pnr	pannier	0.180
phl	pole hole	0.178
en	engrailed	0.170
N	Notch	0.166	Mouse
shn	schnurri	0.166
Dcr-1	Dicer-1	0.165
Wnt4	Wnt oncogene analog 4	0.164
pygo	pygopus	0.159
yki	yorkie	0.150	Human
Mad	Mothers against dpp	0.150
ush	u-shaped	0.149
vg	vestigial	0.144
Ubx	Ultrabithorax	0.141
neur	neuralized	0.140
hbs	hibris	0.139
Rbf	Retinoblastoma-family protein	0.138
Klp64D	Kinesin-like protein at 64D	0.135
eya	eyes absent	0.126
Ras85D	Ras oncogene at 85D	0.120
Sulf1	Sulfated	0.119
Caf1	Chromatin assembly factor 1 subunit	0.116
CycA	Cyclin A	0.110
arm	armadillo	0.106	Zebrafish
Bj1	Bj1 protein	0.099
fwd	four wheel drive	0.096
rin	rasputin	0.093	Mouse
jumu	jumeau	0.092
krz	kurtz	0.090
Tor	Target of rapamycin	0.082
nej	nejire	0.081
ap	apterous	0.077
Cdk4	Cyclin-dependent kinase 4	0.074
slpr	slipper	0.073
Notum	CG13076 gene product from transcript CG13076-RB	0.071
hpo	hippo	0.070
if	inflated	0.069
wdb	widerborst	0.068
Usp7	ubiquitin-specific protease 7	0.066
l(2)gl	lethal (2) giant larvae	0.061
ft	fat	0.059
lig	lingerer	0.057
Tak1	TGF-beta activated kinase 1	0.056
CG6234	CG6234 gene product from transcript CG6234-RA	0.055
toy	twin of eyeless	0.055
capt	capulet	0.053
Rac1	CG2248 gene product from transcript CG2248-RA	0.053
aPKC	atypical protein kinase C	0.053
Axn	Axin	0.053
CycE	Cyclin E	0.052
ab	abrupt	0.052
tsr	twinstar	0.049
ftz-f1	ftz transcription factor 1	0.049
slmb	supernumerary limbs	0.047
jar	jaguar	0.046
lgs	legless	0.046
sfl	sulfateless	0.046
sno	strawberry notch	0.046
brk	brinker	0.045
opa	odd paired	0.045
Mes2	CG11100 gene product from transcript CG11100-RB	0.044
Sce	Sex combs extra	0.044
CG17273	CG17273 gene product from transcript CG17273-RA	0.043
mys	myospheroid	0.043
l(2)05510	lethal (2) 05510	0.043
scny	scrawny	0.042
Traf4	TNF-receptor-associated factor 4	0.042
S6k	RPS6-p70-protein kinase	0.041
CG5794	CG5794 gene product from transcript CG5794-RB	0.041
cdi	center divider	0.040
nmo	nemo	0.040
ssh	slingshot	0.039
Pkd2	Polycystic kidney disease gene-2	0.038
caup	caupolican	0.038
so	sine oculis	0.038
Tollo	CG6890 gene product from transcript CG6890-RA	0.038
Tl	Toll	0.038
Apc2	Adenomatous polyposis coli tumor suppressor homolog 2	0.038
InR	Insulin-like receptor	0.037
slp1	sloppy paired 1	0.036
fkh	fork head	0.036
Pten	CG5671 gene product from transcript CG5671-RB	0.035
CG32556	CG32556 gene product from transcript CG32556-RB	0.035
bdg	bedraggled	0.035
Max	CG9648 gene product from transcript CG9648-RA	0.035
dpp	decapentaplegic	0.035	Human
hfw	halfway	0.035
Hsf	Heat shock factor	0.034
cln3	CG5582 gene product from transcript CG5582-RA	0.034
sina	seven in absentia	0.034
cbt	cabut	0.034
ara	araucan	0.033
a6	CG3771 gene product from transcript CG3771-RA	0.032
pbl	pebble	0.032
sens	senseless	0.032
wb	wing blister	0.032
arr	arrow	0.032	Mouse
D	Dichaete	0.031
trbl	tribbles	0.031
CG14869	CG14869 gene product from transcript CG14869-RB	0.031
msn	misshapen	0.031
nub	nubbin	0.030
hth	homothorax	0.030
frtz	fritz	0.030
mew	multiple edematous wings	0.030
Kr	Kruppel	0.030
rok	Rho-kinase	0.029
cutlet	CG33122 gene product from transcript CG33122-RA	0.029
ttv	tout-velu	0.028
sgg	shaggy	0.027	Worm
Socs36E	Suppressor of cytokine signaling at 36E	0.027
SoxN	SoxNeuro	0.027	Human Mouse
lbl	ladybird late	0.027
btz	barentsz	0.027
fz2	frizzled 2	0.026	Zebrafish
ed	echinoid	0.026
pk	prickle	0.025	Human
Fmr1	CG6203 gene product from transcript CG6203-RC	0.025
Mekk1	CG7717 gene product from transcript CG7717-RB	0.025
bs	blistered	0.025
insc	inscuteable	0.025
armi	armitage	0.025
LamC	Lamin C	0.025
Antp	Antennapedia	0.024
kn	knot	0.024
topi	matotopetli	0.024
Mpk2	CG5475 gene product from transcript CG5475-RB	0.024	Mouse
park	parkin	0.024
CG18806	CG18806 gene product from transcript CG18806-RA	0.024
Jarid2	CG3654 gene product from transcript CG3654-RD	0.024
in	inturned	0.023
E(z)	Enhancer of zeste	0.023
stan	starry night	0.023
Cdk9	Cyclin-dependent kinase 9	0.023
Wnt2	Wnt oncogene analog 2	0.023
egr	eiger	0.023
puc	puckered	0.023
sna	snail	0.023	Human
emc	extra macrochaetae	0.022
A3-3	CG11405 gene product from transcript CG11405-RA	0.022
l(1)G0007	lethal (1) G0007	0.022
CG5746	CG5746 gene product from transcript CG5746-RB	0.022
eyg	eyegone	0.022
CG3371	CG3371 gene product from transcript CG3371-RA	0.021
POSH	Plenty of SH3s	0.021
Eip93F	CG18389 gene product from transcript CG18389-RB	0.021
tth	toothrin	0.021
rst	roughest	0.021
btsz	bitesize	0.021
tio	tiptop	0.021
Gga	CG3002 gene product from transcript CG3002-RB	0.021
drk	downstream of receptor kinase	0.021
S6kII	RPS6-protein kinase-II	0.021
raw	CG12437 gene product from transcript CG12437-RB	0.020
CG18528	CG18528 gene product from transcript CG18528-RA	0.020
ptc	patched	0.020
CG10376	CG10376 gene product from transcript CG10376-RA	0.020
bond	james bond	0.020
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.020
Btk29A	Btk family kinase at 29A	0.020	Zebrafish
CG32372	CG32372 gene product from transcript CG32372-RA	0.020
babo	baboon	0.019
Abl	Abl tyrosine kinase	0.019
put	punt	0.019
Pp2B-14D	Protein phosphatase 2B at 14D	0.019
Pvr	PDGF- and VEGF-receptor related	0.019
Trim9	CG31721 gene product from transcript CG31721-RB	0.018
mbl	muscleblind	0.018
tup	tailup	0.018	Mouse
rn	rotund	0.018
Rip11	Rab11 interacting protein	0.018
mib1	mind bomb 1	0.018
Gef26	CG9491 gene product from transcript CG9491-RB	0.018
CG11275	CG11275 gene product from transcript CG11275-RA	0.018
R	Roughened	0.018
CG32354	CG32354 gene product from transcript CG32354-RA	0.018
Sbf	SET domain binding factor	0.018
Tsc1	CG6147 gene product from transcript CG6147-RA	0.017
lft	lowfat	0.017
sog	short gastrulation	0.017
CG9588	CG9588 gene product from transcript CG9588-RA	0.017
Tom	Twin of m4	0.017
Myo31DF	Myosin 31DF	0.017
Dsor1	Downstream of raf1	0.017
ro	rough	0.017
Chrac-16	CG15736 gene product from transcript CG15736-RA	0.017
snk	snake	0.017
csw	corkscrew	0.017
A2bp1	Ataxin-2 binding protein 1	0.017
numb	CG3779 gene product from transcript CG3779-RB	0.017
fu	fused	0.017
nct	nicastrin	0.017
ago	archipelago	0.017
retn	retained	0.017
sll	slalom	0.017
Lim3	CG10699 gene product from transcript CG10699-RB	0.016
Kr-h1	Kruppel homolog 1	0.016
Pka-C1	cAMP-dependent protein kinase 1	0.016
mol	moladietz	0.016
pes	peste	0.016
CG31352	CG31352 gene product from transcript CG31352-RA	0.016
ric8a	CG15797 gene product from transcript CG15797-RA	0.016
nvy	nervy	0.016
iav	inactive	0.016
drpr	draper	0.016
Vps33B	Vacuolar protein sorting 33B	0.016
CrebA	Cyclic-AMP response element binding protein A	0.016
CycC	Cyclin C	0.016
CG4282	CG4282 gene product from transcript CG4282-RA	0.016
wor	worniu	0.016
Mef2	Myocyte enhancer factor 2	0.016
dib	disembodied	0.016
pburs	partner of burs	0.015
dbo	diablo	0.015
CG4168	CG4168 gene product from transcript CG4168-RA	0.015
CG17565	CG17565 gene product from transcript CG17565-RA	0.015
Eip74EF	Ecdysone-induced protein 74EF	0.015	Fly
os	outstretched	0.015
not	non-stop	0.015
twin	CG31137 gene product from transcript CG31137-RB	0.015
CG2269	CG2269 gene product from transcript CG2269-RC	0.015
Gug	Grunge	0.015
Ser	Serrate	0.015
CG32813	CG32813 gene product from transcript CG32813-RE	0.015
Ten-m	Tenascin major	0.015
l(2)03659	lethal (2) 03659	0.015
Ptp69D	Protein tyrosine phosphatase 69D	0.015
CG6406	CG6406 gene product from transcript CG6406-RA	0.015
l(2)35Bd	lethal (2) 35Bd	0.015
CG10979	CG10979 gene product from transcript CG10979-RA	0.014
sbb	scribbler	0.014
run	runt	0.014
Mnt	CG13316 gene product from transcript CG13316-RD	0.014
tok	tolkin	0.014
dyn-p25	dynactin-subunit-p25	0.014
CG10348	CG10348 gene product from transcript CG10348-RB	0.014
tna	tonalli	0.014
Rab23	CG2108 gene product from transcript CG2108-RA	0.014
Su(H)	Suppressor of Hairless	0.014
rib	ribbon	0.014
CG9541	CG9541 gene product from transcript CG9541-RA	0.014
tsg	twisted gastrulation	0.014
slbo	slow border cells	0.014
cno	canoe	0.014
mal	maroon-like	0.014
CG10466	CG10466 gene product from transcript CG10466-RA	0.014
pasha	partner of drosha	0.014
CG7609	CG7609 gene product from transcript CG7609-RB	0.014
Poxm	Pox meso	0.014
bon	bonus	0.014
kek5	kekkon5	0.014
dco	discs overgrown	0.013	Mouse
Sox14	Sox box protein 14	0.013
CG4596	CG4596 gene product from transcript CG4596-RA	0.013
chb	chromosome bows	0.013
CG31108	CG31108 gene product from transcript CG31108-RA	0.013
tyn	trynity	0.013
gsb	gooseberry	0.013
CG5934	CG5934 gene product from transcript CG5934-RA	0.013
frc	fringe connection	0.013
cora	coracle	0.013
EDTP	Egg-derived tyrosine phosphatase	0.013
l(2)08717	lethal (2) 08717	0.013
simj	simjang	0.013
CG11284	CG11284 gene product from transcript CG11284-RA	0.013
CycB	Cyclin B	0.013
Z600	CG17962 gene product from transcript CG17962-RA	0.013
danr	distal antenna-related	0.012
CG4341	CG4341 gene product from transcript CG4341-RB	0.012
Sdc	Syndecan	0.012
CG8909	CG8909 gene product from transcript CG8909-RC	0.012	Human
Moe	Moesin	0.012
nimC3	nimrod C3	0.012
Mst77F	Male-specific transcript 77F	0.012
Mio	Mlx interactor	0.012
onecut	CG1922 gene product from transcript CG1922-RA	0.012
grn	grain	0.012
Acf1	ATP-dependent chromatin assembly factor large subunit	0.012
PGRP-LC	Peptidoglycan recognition protein LC	0.012
CG5337	CG5337 gene product from transcript CG5337-RA	0.012
H2.0	Homeodomain protein 2.0	0.012
shd	shade	0.012
LanA	Laminin A	0.012
polo	CG12306 gene product from transcript CG12306-RA	0.012
Syx1A	Syntaxin 1A	0.012
dgo	diego	0.012
por	porcupine	0.012
CG6912	CG6912 gene product from transcript CG6912-RA	0.012
row	relative of woc	0.012
Ulp1	CG12359 gene product from transcript CG12359-RA	0.012
CG42856	CG42856 gene product from transcript CG42856-RC	0.012
Lcch3	Ligand-gated chloride channel homolog 3	0.012
Eip71CD	Ecdysone-induced protein 28/29kD	0.012
smt3	CG4494 gene product from transcript CG4494-RA	0.012
CG1625	CG1625 gene product from transcript CG1625-RB	0.012
CG9304	CG9304 gene product from transcript CG9304-RA	0.012
pip	pipe	0.012
Mbs	Myosin binding subunit	0.011
CG13597	CG13597 gene product from transcript CG13597-RA	0.011
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.011
Dip3	Dorsal interacting protein 3	0.011
Dredd	Death related ced-3/Nedd2-like protein	0.011
trr	trithorax-related	0.011
ovo	CG6824 gene product from transcript CG6824-RE	0.011
CG18766	CG18766 gene product from transcript CG18766-RB	0.011
RYBP	Ring and YY1 Binding Protein	0.011
CG10426	CG10426 gene product from transcript CG10426-RA	0.011
amx	almondex	0.011
CG6405	CG6405 gene product from transcript CG6405-RA	0.011
klhl10	CG12423 gene product from transcript CG12423-RB	0.011
Chi	Chip	0.011
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.011
garz	gartenzwerg	0.011
CG14709	CG14709 gene product from transcript CG14709-RB	0.011
inx3	innexin 3	0.011
fs(1)h	female sterile (1) homeotic	0.011
CG8486	CG8486 gene product from transcript CG8486-RE	0.011
LIMK1	LIM-kinase1	0.011
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.011
lin	lines	0.011
amos	absent MD neurons and olfactory sensilla	0.011
Megalin	CG42611 gene product from transcript CG42611-RA	0.011
Vps28	Vacuolar protein sorting 28	0.011
sNPF-R	short neuropeptide F receptor	0.011
MED11	Mediator complex subunit 11	0.011
Jra	Jun-related antigen	0.011
Indy	I'm not dead yet	0.011
SF2	CG6987 gene product from transcript CG6987-RA	0.011
CG4953	CG4953 gene product from transcript CG4953-RA	0.011
chico	CG5686 gene product from transcript CG5686-RB	0.011
Trf2	TATA box binding protein-related factor 2	0.011
fliI	flightless I	0.011
CG4078	CG4078 gene product from transcript CG4078-RA	0.010
CG14868	CG14868 gene product from transcript CG14868-RA	0.010
fzo	fuzzy onions	0.010
mirr	mirror	0.010
jhamt	juvenile hormone acid methyltransferase	0.010
Oli	Olig family	0.010
barr	barren	0.010
CG12299	CG12299 gene product from transcript CG12299-RA	0.010
fas	faint sausage	0.010
Dr	Drop	0.010
kkv	krotzkopf verkehrt	0.010
CG1368	CG1368 gene product from transcript CG1368-RA	0.010
Dl	Delta	0.010
Rala	Ras-related protein	0.010