IMP
Process View
positive regulation of proteolysis involved in cellular protein catabolic process
Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteolysis involved in cellular protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.998 | Yeast | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.982 | ||
| SMAD4 | SMAD family member 4 | 0.946 | Human | |
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.915 | Yeast Fly | |
| SMAD3 | SMAD family member 3 | 0.876 | Human | |
| SMAD2 | SMAD family member 2 | 0.823 | Human | |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.790 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.740 | Human | |
| TP53 | tumor protein p53 | 0.718 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.702 | ||
| UBC | ubiquitin C | 0.690 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.658 | Human | |
| SMAD1 | SMAD family member 1 | 0.643 | Human | |
| SMAD5 | SMAD family member 5 | 0.636 | Human | |
| CSNK1E | casein kinase 1, epsilon | 0.607 | Mouse Fly | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.598 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.573 | Mouse Fly | |
| CUL2 | cullin 2 | 0.481 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.466 | ||
| SMAD7 | SMAD family member 7 | 0.459 | ||
| UBQLN1 | ubiquilin 1 | 0.432 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.426 | ||
| RNF11 | ring finger protein 11 | 0.423 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.399 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.320 | ||
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.267 | ||
| EPOR | erythropoietin receptor | 0.266 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.245 | ||
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.231 | Human | |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.215 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.210 | ||
| SKIL | SKI-like oncogene | 0.206 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.203 | ||
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.195 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.194 | Mouse | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.194 | ||
| TADA3 | transcriptional adaptor 3 | 0.184 | ||
| SMC6 | structural maintenance of chromosomes 6 | 0.183 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.183 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.180 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.178 | ||
| PSEN1 | presenilin 1 | 0.176 | Mouse | |
| PLK1 | polo-like kinase 1 | 0.156 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.156 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.154 | Mouse | |
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.146 | ||
| CUL5 | cullin 5 | 0.145 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.143 | Yeast | |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.137 | ||
| AURKB | aurora kinase B | 0.136 | ||
| JUN | jun proto-oncogene | 0.126 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.126 | ||
| ATXN3 | ataxin 3 | 0.125 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.122 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.117 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.116 | Yeast | |
| HDAC6 | histone deacetylase 6 | 0.108 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.107 | Fly | |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.106 | ||
| PRNP | prion protein | 0.097 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.091 | Yeast | |
| DAXX | death-domain associated protein | 0.089 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.089 | ||
| CSNK1D | casein kinase 1, delta | 0.087 | Mouse Fly | |
| SOCS2 | suppressor of cytokine signaling 2 | 0.086 | Human | |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.085 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.084 | ||
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.084 | ||
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.083 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.079 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.079 | ||
| BRCA1 | breast cancer 1, early onset | 0.077 | ||
| CUL1 | cullin 1 | 0.077 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.076 | ||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.073 | Yeast | |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.073 | ||
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.072 | ||
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.072 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.070 | ||
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.069 | ||
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.067 | ||
| PDCD10 | programmed cell death 10 | 0.065 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.065 | ||
| AXIN1 | axin 1 | 0.065 | Mouse Rat | |
| CDK2 | cyclin-dependent kinase 2 | 0.064 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.063 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.063 | ||
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.062 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.062 | Fly | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.061 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.061 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.060 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.060 | ||
| ATF5 | activating transcription factor 5 | 0.058 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.057 | Human | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.056 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.056 | ||
| ZNF746 | zinc finger protein 746 | 0.056 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.055 | ||
| BAG2 | BCL2-associated athanogene 2 | 0.054 | ||
| JAK2 | Janus kinase 2 | 0.053 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.053 | ||
| BAG1 | BCL2-associated athanogene | 0.052 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.051 | ||
| RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.051 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.051 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.051 | Human Mouse | |
| STIP1 | stress-induced-phosphoprotein 1 | 0.050 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.050 | Human | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.049 | ||
| TBP | TATA box binding protein | 0.048 | ||
| EEF2 | eukaryotic translation elongation factor 2 | 0.048 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.047 | ||
| TUBA1C | tubulin, alpha 1c | 0.046 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.043 | Human | |
| RB1 | retinoblastoma 1 | 0.043 | ||
| ERBB2IP | erbb2 interacting protein | 0.043 | ||
| HSPA4 | heat shock 70kDa protein 4 | 0.043 | ||
| FUNDC2 | FUN14 domain containing 2 | 0.042 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.040 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.040 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.040 | ||
| CXXC5 | CXXC finger protein 5 | 0.039 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.039 | ||
| UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.039 | Fly | |
| CREBBP | CREB binding protein | 0.038 | ||
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.038 | ||
| MAK | male germ cell-associated kinase | 0.038 | ||
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.038 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.037 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.036 | ||
| SIRT2 | sirtuin 2 | 0.036 | ||
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.035 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.035 | Yeast | |
| JUNB | jun B proto-oncogene | 0.035 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.035 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.035 | ||
| CLSPN | claspin | 0.035 | ||
| HSPA8 | heat shock 70kDa protein 8 | 0.034 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.034 | Human | |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.033 | ||
| BBS9 | Bardet-Biedl syndrome 9 | 0.033 | ||
| E2F5 | E2F transcription factor 5, p130-binding | 0.033 | ||
| RHOA | ras homolog gene family, member A | 0.033 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.033 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.032 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.031 | ||
| STAG1 | stromal antigen 1 | 0.031 | ||
| SCNN1B | sodium channel, nonvoltage-gated 1, beta | 0.031 | ||
| ANAPC1 | anaphase promoting complex subunit 1 | 0.030 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.030 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.030 | Mouse | |
| UBE3A | ubiquitin protein ligase E3A | 0.030 | Fly | |
| POLH | polymerase (DNA directed), eta | 0.030 | ||
| SAE1 | SUMO1 activating enzyme subunit 1 | 0.030 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.029 | ||
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.029 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.029 | ||
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.029 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.029 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.028 | ||
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.028 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.028 | ||
| AR | androgen receptor | 0.028 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.028 | ||
| DDIT3 | DNA-damage-inducible transcript 3 | 0.028 | ||
| E2F4 | E2F transcription factor 4, p107/p130-binding | 0.028 | ||
| GORAB | golgin, RAB6-interacting | 0.027 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.027 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.027 | ||
| CCND1 | cyclin D1 | 0.026 | ||
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.026 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.026 | ||
| MAP1A | microtubule-associated protein 1A | 0.026 | ||
| CDK9 | cyclin-dependent kinase 9 | 0.026 | ||
| CUL4A | cullin 4A | 0.026 | ||
| ATF3 | activating transcription factor 3 | 0.025 | ||
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.025 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.024 | ||
| TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 | 0.024 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.024 | ||
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.024 | ||
| C1D | C1D nuclear receptor corepressor | 0.024 | ||
| FLNB | filamin B, beta | 0.024 | ||
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.024 | ||
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.024 | ||
| SPTBN4 | spectrin, beta, non-erythrocytic 4 | 0.023 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.023 | ||
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.023 | ||
| ANKRD13A | ankyrin repeat domain 13A | 0.022 | ||
| CCNA2 | cyclin A2 | 0.022 | ||
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.022 | ||
| CCNE1 | cyclin E1 | 0.022 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.022 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.022 | ||
| CCNB1 | cyclin B1 | 0.022 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.022 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.022 | ||
| BCL2L1 | BCL2-like 1 | 0.021 | ||
| SMAD6 | SMAD family member 6 | 0.021 | Human | |
| SHPRH | SNF2 histone linker PHD RING helicase | 0.021 | ||
| RANBP9 | RAN binding protein 9 | 0.021 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.021 | ||
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.021 | ||
| BTBD2 | BTB (POZ) domain containing 2 | 0.021 | ||
| PUF60 | poly-U binding splicing factor 60KDa | 0.021 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.021 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.021 | ||
| ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.021 | ||
| TRIM63 | tripartite motif containing 63 | 0.021 | ||
| HSF1 | heat shock transcription factor 1 | 0.020 | ||
| FAF2 | Fas associated factor family member 2 | 0.020 | ||
| APP | amyloid beta (A4) precursor protein | 0.020 | ||
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.020 | ||
| MEMO1 | mediator of cell motility 1 | 0.020 | ||
| HDAC11 | histone deacetylase 11 | 0.020 | ||
| PPP1R14A | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 0.020 | ||
| AXIN2 | axin 2 | 0.020 | ||
| FEM1B | fem-1 homolog b (C. elegans) | 0.020 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.020 | ||
| WNK1 | WNK lysine deficient protein kinase 1 | 0.019 | ||
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.019 | ||
| JUND | jun D proto-oncogene | 0.019 | ||
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.019 | ||
| PRKCZ | protein kinase C, zeta | 0.019 | ||
| ANAPC13 | anaphase promoting complex subunit 13 | 0.019 | ||
| POMP | proteasome maturation protein | 0.019 | ||
| CEP164 | centrosomal protein 164kDa | 0.019 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.019 | ||
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.018 | ||
| SOX7 | SRY (sex determining region Y)-box 7 | 0.018 | ||
| E2F1 | E2F transcription factor 1 | 0.018 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.018 | ||
| GHR | growth hormone receptor | 0.018 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.018 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.018 | ||
| RPL11 | ribosomal protein L11 | 0.018 | ||
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.018 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.018 | ||
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.018 | ||
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.017 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.017 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.017 | ||
| UBXN7 | UBX domain protein 7 | 0.017 | ||
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.017 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.017 | ||
| SETDB1 | SET domain, bifurcated 1 | 0.017 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.017 | ||
| WT1 | Wilms tumor 1 | 0.017 | ||
| TTC35 | tetratricopeptide repeat domain 35 | 0.017 | ||
| MAP1S | microtubule-associated protein 1S | 0.017 | ||
| MYO6 | myosin VI | 0.017 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.017 | ||
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.017 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.016 | ||
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.016 | ||
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.016 | ||
| RAP1B | RAP1B, member of RAS oncogene family | 0.016 | ||
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.016 | ||
| AIG1 | androgen-induced 1 | 0.016 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.016 | ||
| MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.016 | ||
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.016 | ||
| ARHGAP5 | Rho GTPase activating protein 5 | 0.016 | ||
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.016 | ||
| WWOX | WW domain containing oxidoreductase | 0.016 | ||
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.016 | ||
| RNF111 | ring finger protein 111 | 0.015 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.015 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.015 | ||
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.015 | ||
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.015 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.015 | ||
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.015 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.015 | ||
| MNAT1 | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 0.015 | ||
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.015 | ||
| YAP1 | Yes-associated protein 1 | 0.015 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.015 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.015 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.015 | ||
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.015 | ||
| NCSTN | nicastrin | 0.015 | ||
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.015 | Yeast | |
| PIM1 | pim-1 oncogene | 0.015 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.015 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.014 | ||
| MCC | mutated in colorectal cancers | 0.014 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.014 | ||
| LIN54 | lin-54 homolog (C. elegans) | 0.014 | ||
| TROAP | trophinin associated protein (tastin) | 0.014 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.014 | ||
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.014 | ||
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.014 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.014 | ||
| FBXO5 | F-box protein 5 | 0.014 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.014 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.014 | ||
| S100A4 | S100 calcium binding protein A4 | 0.014 | ||
| PIAS3 | protein inhibitor of activated STAT, 3 | 0.014 | ||
| RYBP | RING1 and YY1 binding protein | 0.014 | ||
| MAPT | microtubule-associated protein tau | 0.014 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.014 | ||
| FAM82A2 | family with sequence similarity 82, member A2 | 0.014 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.014 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.014 | ||
| UBQLN2 | ubiquilin 2 | 0.014 | ||
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.014 | ||
| MED28 | mediator complex subunit 28 | 0.014 | ||
| NLK | nemo-like kinase | 0.014 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.014 | ||
| STAG2 | stromal antigen 2 | 0.014 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.014 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.014 | ||
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.014 | ||
| HSPA2 | heat shock 70kDa protein 2 | 0.014 | ||
| SENP1 | SUMO1/sentrin specific peptidase 1 | 0.013 | ||
| ARL15 | ADP-ribosylation factor-like 15 | 0.013 | ||
| GTF2F1 | general transcription factor IIF, polypeptide 1, 74kDa | 0.013 | ||
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.013 | ||
| CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.013 | ||
| BEGAIN | brain-enriched guanylate kinase-associated homolog (rat) | 0.013 | ||
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.013 | ||
| NDFIP2 | Nedd4 family interacting protein 2 | 0.013 | ||
| ING2 | inhibitor of growth family, member 2 | 0.013 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.013 | ||
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.013 | ||
| SOCS4 | suppressor of cytokine signaling 4 | 0.013 | Human | |
| HMGB2 | high mobility group box 2 | 0.013 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.013 | ||
| USP2 | ubiquitin specific peptidase 2 | 0.013 | Fly | |
| GFI1B | growth factor independent 1B transcription repressor | 0.013 | ||
| SCAF11 | SR-related CTD-associated factor 11 | 0.013 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.013 | ||
| POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.013 | ||
| RNF168 | ring finger protein 168 | 0.013 | ||
| ARRDC3 | arrestin domain containing 3 | 0.013 | ||
| PTPRS | protein tyrosine phosphatase, receptor type, S | 0.012 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.012 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.012 | ||
| TTK | TTK protein kinase | 0.012 | ||
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.012 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.012 | ||
| BEND5 | BEN domain containing 5 | 0.012 | ||
| ANAPC10 | anaphase promoting complex subunit 10 | 0.012 | Yeast | |
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.012 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.012 | Fly | |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.012 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.012 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.012 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.012 | ||
| SRI | sorcin | 0.012 | ||
| RAD21 | RAD21 homolog (S. pombe) | 0.012 | ||
| FNBP1L | formin binding protein 1-like | 0.012 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.012 | ||
| RAB5B | RAB5B, member RAS oncogene family | 0.012 | ||
| CDCA3 | cell division cycle associated 3 | 0.012 | ||
| MMS22L | MMS22-like, DNA repair protein | 0.012 | ||
| FRMD6 | FERM domain containing 6 | 0.012 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.012 | ||
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.012 | ||
| NCK2 | NCK adaptor protein 2 | 0.012 | ||
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.012 | ||
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.012 | ||
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.012 | ||
| ETV5 | ets variant 5 | 0.012 | ||
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.012 | ||
| MAP1B | microtubule-associated protein 1B | 0.011 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.011 | ||
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.011 | ||
| TRIM32 | tripartite motif containing 32 | 0.011 | ||
| TIFA | TRAF-interacting protein with forkhead-associated domain | 0.011 | ||
| KALRN | kalirin, RhoGEF kinase | 0.011 | ||
| PTEN | phosphatase and tensin homolog | 0.011 | ||
| CCDC141 | coiled-coil domain containing 141 | 0.011 | ||
| E2F2 | E2F transcription factor 2 | 0.011 | ||
| KIF1B | kinesin family member 1B | 0.011 | ||
| KIF18A | kinesin family member 18A | 0.011 | ||
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.011 | ||
| MAX | MYC associated factor X | 0.011 | ||
| ZNF512B | zinc finger protein 512B | 0.011 | ||
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.011 | ||
| TUBA1A | tubulin, alpha 1a | 0.011 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.011 | ||
| DOCK8 | dedicator of cytokinesis 8 | 0.011 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.011 | ||
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.011 | ||
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.011 | ||
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.011 | ||
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.011 | ||
| FAM83D | family with sequence similarity 83, member D | 0.011 | ||
| PINK1 | PTEN induced putative kinase 1 | 0.011 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.011 | ||
| FES | feline sarcoma oncogene | 0.011 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.011 | ||
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.011 | ||
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.011 | ||
| MKL2 | MKL/myocardin-like 2 | 0.011 | ||
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 | 0.011 | ||
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 0.011 | ||
| EXT2 | exostosin 2 | 0.011 | ||
| KCTD3 | potassium channel tetramerisation domain containing 3 | 0.011 | ||
| EPHA8 | EPH receptor A8 | 0.011 | ||
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.011 | ||
| DEDD | death effector domain containing | 0.011 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.011 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.011 | Fly | |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.011 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.011 | ||
| GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.011 | ||
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.010 | ||
| USP20 | ubiquitin specific peptidase 20 | 0.010 | ||
| BAHD1 | bromo adjacent homology domain containing 1 | 0.010 | ||
| NEFL | neurofilament, light polypeptide | 0.010 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.010 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.010 | ||
| JAM2 | junctional adhesion molecule 2 | 0.010 | ||
| ZNF295 | zinc finger protein 295 | 0.010 | ||
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 0.010 | ||
| FHL2 | four and a half LIM domains 2 | 0.010 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.010 | ||
| RBM4 | RNA binding motif protein 4 | 0.010 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.010 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.010 | ||
| PML | promyelocytic leukemia | 0.010 | ||
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.010 | ||
| DEPDC1 | DEP domain containing 1 | 0.010 | ||
| FRZB | frizzled-related protein | 0.010 | ||
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.010 | ||
| AAAS | achalasia, adrenocortical insufficiency, alacrimia | 0.010 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.010 | ||
| CISH | cytokine inducible SH2-containing protein | 0.010 | Human | |
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.010 | ||
| MAGEA2 | melanoma antigen family A, 2 | 0.010 | ||
| PRUNE | prune homolog (Drosophila) | 0.010 | ||
| ACVR1 | activin A receptor, type I | 0.010 | ||
| MLF2 | myeloid leukemia factor 2 | 0.010 |