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Drosophila melanogaster

26 genes annotated in fly

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double strand break repair

GO:0006302

The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "double strand break repair"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "double strand break repair" (in gray)

Name	Description	Probability	Func Analog Organism
mus205	mutagen-sensitive 205	0.999
okr	okra	0.998
lok	loki	0.996	Human
DNApol-eta	CG7143 gene product from transcript CG7143-RA	0.992
Irbp	Inverted repeat-binding protein	0.987
Mcm2	Minichromosome maintenance 2	0.984	Yeast
mus308	mutagen-sensitive 308	0.975
RpA-70	Replication Protein A 70	0.964	Human
mei-9	meiotic 9	0.960
tefu	telomere fusion	0.952
mus101	mutagen-sensitive 101	0.948
p53	CG33336 gene product from transcript CG33336-RB	0.944	Mouse
spn-A	spindle A	0.938
Brca2	Breast cancer 2, early onset homolog	0.937
CG5524	CG5524 gene product from transcript CG5524-RA	0.937
rad50	CG6339 gene product from transcript CG6339-RD	0.936
mus301	mutagen-sensitive 301	0.889	Human Fly
hay	haywire	0.888
mus201	mutagen-sensitive 201	0.856	Worm
mus210	mutagen-sensitive 210	0.856
RfC4	Replication factor C subunit 4	0.789
mre11	meiotic recombination 11	0.775	Yeast Mouse
RecQ5	homolog of RecQ	0.743
Rev1	CG12189 gene product from transcript CG12189-RA	0.741
mus309	mutagen-sensitive 309	0.727
Cks30A	Cyclin-dependent kinase subunit 30A	0.727
Mcm3	Minichromosome maintenance 3	0.673	Yeast
mus304	mutagen-sensitive 304	0.652
spn-B	spindle B	0.635	Human
mei-41	meiotic 41	0.618
RecQ4	CG7487 gene product from transcript CG7487-RA	0.601
Mcm6	Minichromosome maintenance 6	0.562	Yeast
Ercc1	CG10215 gene product from transcript CG10215-RA	0.501	Mouse
E(z)	Enhancer of zeste	0.484
RnrL	Ribonucleoside diphosphate reductase large subunit	0.476
CG13350	CG13350 gene product from transcript CG13350-RA	0.423
CDC45L	CG3658 gene product from transcript CG3658-RA	0.392	Yeast
Mcm5	Minichromosome maintenance 5	0.391	Yeast
CG8142	CG8142 gene product from transcript CG8142-RA	0.385
CG9576	CG9576 gene product from transcript CG9576-RA	0.327
cutlet	CG33122 gene product from transcript CG33122-RA	0.323
RfC3	Replication factor C subunit 3	0.293
CSN4	COP9 complex homolog subunit 4	0.288
CG16908	CG16908 gene product from transcript CG16908-RA	0.281
CG2694	CG2694 gene product from transcript CG2694-RA	0.269
Smc5	CG32438 gene product from transcript CG32438-RE	0.263
CG5857	CG5857 gene product from transcript CG5857-RA	0.260
Mcm7	Minichromosome maintenance 7	0.249	Yeast
rasp	CG11495 gene product from transcript CG11495-RA	0.216
spn-E	spindle E	0.203
CycH	Cyclin H	0.186
nbs	CG6754 gene product from transcript CG6754-RC	0.179
WRNexo	WRN exonuclease	0.155
Lig4	Ligase4	0.148
mus312	mutagen-sensitive 312	0.143
CG8247	CG8247 gene product from transcript CG8247-RB	0.128
pie	pineapple eye	0.128
defl	deflated	0.120
mit(1)15	mitotic 15	0.120
RPA2	Replication protein A2	0.112	Human
CG2982	CG2982 gene product from transcript CG2982-RB	0.105
CG5745	CG5745 gene product from transcript CG5745-RA	0.105
pasha	partner of drosha	0.097
MAGE	CG10059 gene product from transcript CG10059-RA	0.095
Mlh1	CG11482 gene product from transcript CG11482-RA	0.092	Mouse
Su(var)2-HP2	CG12864 gene product from transcript CG12864-RB	0.090
CG7099	CG7099 gene product from transcript CG7099-RA	0.088
Gnf1	Germ line transcription factor 1	0.086
Shc	SHC-adaptor protein	0.084
ash2	absent, small, or homeotic discs 2	0.082
Caf1	Chromatin assembly factor 1 subunit	0.081
Nup75	Nucleoporin 75	0.078
cmet	CENP-meta	0.076
CG12391	CG12391 gene product from transcript CG12391-RA	0.073
wdn	wings down	0.072
CG13349	CG13349 gene product from transcript CG13349-RA	0.071
Mcm10	Sensitized chromosome inheritance modifier 19	0.067
DNApol-alpha50	DNA polymerase alpha 50kD	0.066
Top2	Topoisomerase 2	0.065
Uba1	Ubiquitin activating enzyme 1	0.065
DNApol-alpha73	DNA polymerase alpha 73kD	0.063
stwl	stonewall	0.063
png	pan gu	0.062
Pms2	CG8169 gene product from transcript CG8169-RA	0.062
mof	males absent on the first	0.062
ida	imaginal discs arrested	0.061
Caf1-105	CG12892 gene product from transcript CG12892-RA	0.060
Cka	Connector of kinase to AP-1	0.060
CG8963	CG8963 gene product from transcript CG8963-RB	0.054
Rpn3	Regulatory particle non-ATPase 3	0.054
fs(2)ltoPP43	female sterile (2) ltoPP43	0.054
l(2)dtl	lethal-(2)-denticleless	0.053
CG9772	CG9772 gene product from transcript CG9772-RB	0.052
AGO3	Argonaute 3	0.052
DNApol-delta	DNA-polymerase-delta	0.051
D12	CG13400 gene product from transcript CG13400-RA	0.050
scny	scrawny	0.050
hang	hangover	0.049
Rpn1	CG7762 gene product from transcript CG7762-RA	0.049
desat1	CG5887 gene product from transcript CG5887-RA	0.048
Orc4	Origin recognition complex subunit 4	0.048
HipHop	HP1-HOAP-interacting protein	0.047
His2Av	Histone H2A variant	0.046
CG5602	CG5602 gene product from transcript CG5602-RA	0.046	Mouse
Klp61F	Kinesin-like protein at 61F	0.046
Psf3	CG2222 gene product from transcript CG2222-RA	0.046	Yeast
Lrr47	Leucine-rich repeat 47	0.045
CG4673	CG4673 gene product from transcript CG4673-RB	0.045
dlt	discs lost	0.044
chm	chameau	0.041
Aly	CG1101 gene product from transcript CG1101-RA	0.041
ph-d	polyhomeotic distal	0.041
CG4680	CG4680 gene product from transcript CG4680-RA	0.039
CG7376	CG7376 gene product from transcript CG7376-RA	0.039
glu	gluon	0.038
CG7457	CG7457 gene product from transcript CG7457-RA	0.037	Human
Ndc80	CG9938 gene product from transcript CG9938-RA	0.036
fzy	fizzy	0.036
Incenp	Inner centromere protein	0.035
Klp3A	Kinesin-like protein at 3A	0.035
Rpn9	CG10230 gene product from transcript CG10230-RB	0.033
RnrS	Ribonucleoside diphosphate reductase small subunit	0.033
gkt	glaikit	0.032
mrn	marionette	0.032
vih	vihar	0.032
dgt3	dim gamma-tubulin 3	0.032
Rpn6	Proteasome p44.5 subunit	0.032
ApepP	Aminopeptidase P	0.031
Det	Deterin	0.031
RagA	CG11968 gene product from transcript CG11968-RA	0.031
Sas-4	CG10061 gene product from transcript CG10061-RA	0.031
Rpd3	CG7471 gene product from transcript CG7471-RA	0.030
CG18596	CG18596 gene product from transcript CG18596-RA	0.029
tos	tosca	0.029
tld	tolloid	0.029
spn-D	spindle D	0.029	Human
ranshi	CG9793 gene product from transcript CG9793-RA	0.028
mus209	mutagen-sensitive 209	0.028
fy	fuzzy	0.028
CG9705	CG9705 gene product from transcript CG9705-RA	0.028
SMC2	CG10212 gene product from transcript CG10212-RA	0.028
zwilch	CG18729 gene product from transcript CG18729-RA	0.028
nxf2	nuclear RNA export factor 2	0.028
CG12877	CG12877 gene product from transcript CG12877-RC	0.027
Rrp1	Recombination repair protein 1	0.027
rno	rhinoceros	0.027
BRWD3	CG31132 gene product from transcript CG31132-RA	0.026
RanBP3	Ran binding protein 3	0.025
mib1	mind bomb 1	0.025
Ada2b	CG9638 gene product from transcript CG9638-RA	0.025
CG2990	CG2990 gene product from transcript CG2990-RB	0.025
Cdc6	CG5971 gene product from transcript CG5971-RA	0.024
Pros54	Proteasome 54kD subunit	0.024
dmt	dalmatian	0.024
Chrac-14	CG13399 gene product from transcript CG13399-RA	0.024
rump	rumpelstiltskin	0.024
Sym	Symplekin	0.024
CG32251	CG32251 gene product from transcript CG32251-RA	0.023
Orc1	Origin recognition complex subunit 1	0.023
DNApol-epsilon	DNA polymerase epsilon	0.023
CG9752	CG9752 gene product from transcript CG9752-RA	0.023
CG18190	CG18190 gene product from transcript CG18190-RB	0.023
CG14803	CG14803 gene product from transcript CG14803-RA	0.023
CG11403	CG11403 gene product from transcript CG11403-RA	0.023
CG14814	CG14814 gene product from transcript CG14814-RA	0.023
CG7341	CG7341 gene product from transcript CG7341-RB	0.023
Rca1	Regulator of cyclin A1	0.023
ric8a	CG15797 gene product from transcript CG15797-RA	0.022
Rpt1	CG1341 gene product from transcript CG1341-RA	0.022
CG3815	CG3815 gene product from transcript CG3815-RA	0.022
CycJ	Cyclin J	0.022
HLH54F	CG5005 gene product from transcript CG5005-RA	0.022
Orc2	Origin recognition complex subunit 2	0.021
CG15220	CG15220 gene product from transcript CG15220-RA	0.021
Pabp2	CG2163 gene product from transcript CG2163-RA	0.021
cav	caravaggio	0.021
Ku80	CG18801 gene product from transcript CG18801-RA	0.021
rhi	rhino	0.021
CG12942	CG12942 gene product from transcript CG12942-RA	0.021
CG5871	CG5871 gene product from transcript CG5871-RA	0.020
CG31864	CG31864 gene product from transcript CG31864-RA	0.020
CG5543	CG5543 gene product from transcript CG5543-RA	0.020
ed	echinoid	0.020
cort	cortex	0.020
omd	oocyte maintenance defects	0.020
Pros35	Proteasome 35kD subunit	0.019
CTCF	CG8591 gene product from transcript CG8591-RA	0.019
Pcaf	CG4107 gene product from transcript CG4107-RA	0.019
eIF-4a	Eukaryotic initiation factor 4a	0.019
CG18271	CG18271 gene product from transcript CG18271-RB	0.019
CG9114	CG9114 gene product from transcript CG9114-RA	0.019
Aldh	Aldehyde dehydrogenase	0.018
CG2046	CG2046 gene product from transcript CG2046-RA	0.018
CG3430	CG3430 gene product from transcript CG3430-RA	0.018
Parg	Poly(ADP-ribose) glycohydrolase	0.018
Pgant35A	Polypeptide N-acetylgalactosaminyltransferase 35A	0.018
imd	immune deficiency	0.018
CG15047	CG15047 gene product from transcript CG15047-RA	0.018
CG5366	CG5366 gene product from transcript CG5366-RA	0.018
Pros26	Proteasome 26kD subunit	0.018
Tfb5	CG42373 gene product from transcript CG42373-RB	0.018
out	outsiders	0.018
orb	oo18 RNA-binding protein	0.018
Dok	Downstream of kinase	0.017
cdc23	CG2508 gene product from transcript CG2508-RA	0.017
Pole2	CG10489 gene product from transcript CG10489-RA	0.017
armi	armitage	0.017
His3.3B	Histone H3.3B	0.017
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.017
CAP-D2	CAP-D2 condensin subunit	0.017
dre4	CG1828 gene product from transcript CG1828-RB	0.017
DNApol-iota	CG7602 gene product from transcript CG7602-RB	0.016
hdm	hold'em	0.016
Lsm11	CG12924 gene product from transcript CG12924-RA	0.016
Spc105R	Spc105-related	0.016
trbl	tribbles	0.016
ort	ora transientless	0.016
Nup133	Nucleoporin 133	0.016
Hira	CG12153 gene product from transcript CG12153-RA	0.016
CG16742	CG16742 gene product from transcript CG16742-RA	0.016
CG6927	CG6927 gene product from transcript CG6927-RA	0.016
sle	slender lobes	0.016
Atu	Another transcription unit	0.015
CG3004	CG3004 gene product from transcript CG3004-RA	0.015
Snm1	CG10018 gene product from transcript CG10018-RA	0.015
asf1	anti-silencing factor 1	0.015
pix	pixie	0.015
CG9135	CG9135 gene product from transcript CG9135-RB	0.015
Mnn1	Menin 1	0.015
Awh	Arrowhead	0.015
Mer	Merlin	0.015
Psf1	CG9187 gene product from transcript CG9187-RA	0.015	Yeast
Ssrp	Structure specific recognition protein	0.015
Ube3a	Ubiquitin protein ligase E3A	0.014
Mio	Mlx interactor	0.014
CG6744	CG6744 gene product from transcript CG6744-RA	0.014
CG3437	CG3437 gene product from transcript CG3437-RB	0.014
not	non-stop	0.014
mei-218	meiotic 218	0.014
nod	no distributive disjunction	0.014
CG34455	CG34455 gene product from transcript CG34455-RC	0.014
CG7878	CG7878 gene product from transcript CG7878-RA	0.014
CG12728	CG12728 gene product from transcript CG12728-RA	0.014
CG32104	CG32104 gene product from transcript CG32104-RB	0.014
ana2	anastral spindle 2	0.014
CG5664	CG5664 gene product from transcript CG5664-RA	0.013
Arp8	Actin-related protein 8	0.013	Yeast
zuc	zucchini	0.013
Mes-4	CG4976 gene product from transcript CG4976-RA	0.013	Mouse
CG6194	CG6194 gene product from transcript CG6194-RA	0.013
Fancd2	CG17269 gene product from transcript CG17269-RA	0.013
CG18528	CG18528 gene product from transcript CG18528-RA	0.013
CG12010	CG12010 gene product from transcript CG12010-RA	0.013
CG31918	CG31918 gene product from transcript CG31918-RA	0.013
CG8801	CG8801 gene product from transcript CG8801-RA	0.013
phr	photorepair	0.013
plu	plutonium	0.012
ial	IplI-aurora-like kinase	0.012
gish	gilgamesh	0.012
wdb	widerborst	0.012
RfC38	Replication factor C 38kD subunit	0.012
CG9203	CG9203 gene product from transcript CG9203-RA	0.012
CG14614	CG14614 gene product from transcript CG14614-RA	0.012
slif	slimfast	0.012
Ts	CG3181 gene product from transcript CG3181-RA	0.012
smo	smoothened	0.012
tan	tantalus	0.012
Gen	XPG-like endonuclease	0.012
Spf45	CG17540 gene product from transcript CG17540-RB	0.012
Rpt4	CG3455 gene product from transcript CG3455-RA	0.012
Tfb1	CG8151 gene product from transcript CG8151-RB	0.011
CG1575	CG1575 gene product from transcript CG1575-RA	0.011
TfIIA-L	Transcription factor IIA L	0.011
Nipped-B	CG17704 gene product from transcript CG17704-RI	0.011
gwl	greatwall	0.011
CG3520	CG3520 gene product from transcript CG3520-RA	0.011
CG3975	CG3975 gene product from transcript CG3975-RA	0.011
Uev1A	CG10640 gene product from transcript CG10640-RA	0.011	Human
Ddx1	Dead-box-1	0.011	Human
Tbp-1	Tat-binding protein-1	0.011
sktl	skittles	0.011
tin	tinman	0.011
Ptp61F	Protein tyrosine phosphatase 61F	0.011
CG18213	CG18213 gene product from transcript CG18213-RA	0.011
CG11342	CG11342 gene product from transcript CG11342-RA	0.010
CG17612	CG17612 gene product from transcript CG17612-RB	0.010
CG12321	CG12321 gene product from transcript CG12321-RA	0.010
Orc5	Origin recognition complex subunit 5	0.010
Rep	Rab escort protein	0.010
CG13745	CG13745 gene product from transcript CG13745-RA	0.010
Fit2	Fermitin 2	0.010