IMP
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mitotic dna damage checkpoint
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage.
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Click on a gene's description to view its network relationships with genes known to be involved in "mitotic dna damage checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RB1 | retinoblastoma 1 | 1.000 | ||
| TP53 | tumor protein p53 | 1.000 | ||
| BRCA1 | breast cancer 1, early onset | 1.000 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.999 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.990 | Human | |
| CDK2 | cyclin-dependent kinase 2 | 0.990 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.989 | Fly | |
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.974 | Zebrafish | |
| E2F1 | E2F transcription factor 1 | 0.964 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.953 | ||
| NBN | nibrin | 0.938 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.836 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.832 | Fly | |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.818 | ||
| CDK8 | cyclin-dependent kinase 8 | 0.816 | Fly | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.810 | Human | |
| CUL4A | cullin 4A | 0.759 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.748 | ||
| MCM7 | minichromosome maintenance complex component 7 | 0.736 | Fly | |
| BLM | Bloom syndrome, RecQ helicase-like | 0.722 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.650 | Fly | |
| H2AFX | H2A histone family, member X | 0.635 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.626 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.579 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.566 | Human | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.563 | ||
| PCNA | proliferating cell nuclear antigen | 0.560 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.551 | Fly | |
| ATM | ataxia telangiectasia mutated | 0.540 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.534 | Human | |
| EME1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.505 | ||
| MCM2 | minichromosome maintenance complex component 2 | 0.488 | ||
| CUL1 | cullin 1 | 0.486 | Fly | |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.481 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.471 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.469 | ||
| CCND1 | cyclin D1 | 0.468 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.426 | ||
| PLK1 | polo-like kinase 1 | 0.398 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.387 | ||
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.387 | Fly | |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.383 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.383 | ||
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.381 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.366 | Fly | |
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.343 | Fly | |
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.341 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.332 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.323 | Human | |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.305 | Fly | |
| GFER | growth factor, augmenter of liver regeneration | 0.298 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.296 | ||
| MSH6 | mutS homolog 6 (E. coli) | 0.291 | ||
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.288 | ||
| RPA2 | replication protein A2, 32kDa | 0.282 | ||
| CCNA2 | cyclin A2 | 0.272 | ||
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.264 | ||
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.262 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.248 | Mouse Fly | |
| APAF1 | apoptotic peptidase activating factor 1 | 0.241 | ||
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.226 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.217 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.216 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.211 | ||
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.210 | ||
| CLSPN | claspin | 0.210 | ||
| DAXX | death-domain associated protein | 0.197 | ||
| CCND3 | cyclin D3 | 0.197 | Human | |
| MED1 | mediator complex subunit 1 | 0.196 | ||
| MED28 | mediator complex subunit 28 | 0.188 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.183 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.178 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.172 | ||
| FANCA | Fanconi anemia, complementation group A | 0.172 | ||
| WWOX | WW domain containing oxidoreductase | 0.165 | ||
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.158 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.151 | ||
| CDC45 | cell division cycle 45 homolog (S. cerevisiae) | 0.136 | Fly | |
| GPS1 | G protein pathway suppressor 1 | 0.135 | Fly | |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.135 | ||
| CCNE1 | cyclin E1 | 0.132 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.126 | ||
| HDAC1 | histone deacetylase 1 | 0.125 | ||
| SMAD7 | SMAD family member 7 | 0.122 | ||
| MED23 | mediator complex subunit 23 | 0.122 | ||
| TNRC6B | trinucleotide repeat containing 6B | 0.115 | ||
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.114 | ||
| PRMT6 | protein arginine methyltransferase 6 | 0.110 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.110 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.108 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.107 | ||
| TFDP1 | transcription factor Dp-1 | 0.100 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.098 | ||
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.097 | ||
| MCM6 | minichromosome maintenance complex component 6 | 0.096 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.093 | ||
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 0.093 | ||
| CDK4 | cyclin-dependent kinase 4 | 0.091 | ||
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.086 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.084 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.084 | Human | |
| RPA1 | replication protein A1, 70kDa | 0.077 | Fly | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.076 | ||
| E2F4 | E2F transcription factor 4, p107/p130-binding | 0.074 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.071 | ||
| CSNK2B | casein kinase 2, beta polypeptide | 0.070 | ||
| COPS7A | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.069 | Fly | |
| FBXO11 | F-box protein 11 | 0.067 | ||
| JUN | jun proto-oncogene | 0.067 | Human | |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.067 | ||
| UBXN7 | UBX domain protein 7 | 0.067 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.065 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.063 | Human | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.063 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.063 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.063 | ||
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.062 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.061 | ||
| NCL | nucleolin | 0.061 | ||
| PKM2 | pyruvate kinase, muscle | 0.060 | ||
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.059 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.059 | Human | |
| COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.059 | Fly | |
| EXO1 | exonuclease 1 | 0.058 | ||
| UBE3A | ubiquitin protein ligase E3A | 0.057 | ||
| MED4 | mediator complex subunit 4 | 0.057 | ||
| BRCA2 | breast cancer 2, early onset | 0.057 | ||
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.057 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.056 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.056 | Fly | |
| MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.056 | ||
| CUL2 | cullin 2 | 0.056 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.055 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.055 | ||
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.055 | Fly | |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.054 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.054 | ||
| CUL4B | cullin 4B | 0.054 | Fly | |
| MAPK14 | mitogen-activated protein kinase 14 | 0.053 | ||
| TIMELESS | timeless homolog (Drosophila) | 0.052 | ||
| E2F2 | E2F transcription factor 2 | 0.052 | ||
| RPL39 | ribosomal protein L39 | 0.052 | ||
| MED10 | mediator complex subunit 10 | 0.051 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.051 | ||
| POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.051 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.051 | Human | |
| POU5F1 | POU class 5 homeobox 1 | 0.048 | ||
| CCNDBP1 | cyclin D-type binding-protein 1 | 0.048 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.047 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.047 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.046 | ||
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.045 | ||
| TTI1 | Tel2 interacting protein 1 homolog (S. pombe) | 0.044 | ||
| MED29 | mediator complex subunit 29 | 0.043 | ||
| RBBP4 | retinoblastoma binding protein 4 | 0.043 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.042 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.042 | ||
| CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.041 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.040 | ||
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.040 | ||
| YBX1 | Y box binding protein 1 | 0.039 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.039 | ||
| HDAC2 | histone deacetylase 2 | 0.039 | ||
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.039 | ||
| RECQL | RecQ protein-like (DNA helicase Q1-like) | 0.039 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.039 | ||
| YAP1 | Yes-associated protein 1 | 0.038 | ||
| CCNC | cyclin C | 0.038 | Fly | |
| POLE | polymerase (DNA directed), epsilon | 0.038 | Yeast | |
| RNF20 | ring finger protein 20 | 0.037 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.036 | ||
| SIRT1 | sirtuin 1 | 0.036 | ||
| CUX1 | cut-like homeobox 1 | 0.035 | ||
| MED6 | mediator complex subunit 6 | 0.035 | ||
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.034 | ||
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.034 | ||
| CCNE2 | cyclin E2 | 0.034 | ||
| RAD17 | RAD17 homolog (S. pombe) | 0.034 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.034 | ||
| HABP4 | hyaluronan binding protein 4 | 0.034 | ||
| KRT5 | keratin 5 | 0.032 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.031 | ||
| MEN1 | multiple endocrine neoplasia I | 0.031 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.031 | ||
| POLE2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.031 | ||
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.031 | ||
| CCND2 | cyclin D2 | 0.030 | Human | |
| SRSF2 | serine/arginine-rich splicing factor 2 | 0.030 | ||
| PCGF2 | polycomb group ring finger 2 | 0.030 | ||
| MED26 | mediator complex subunit 26 | 0.030 | ||
| WDR5 | WD repeat domain 5 | 0.030 | Fly | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.030 | ||
| MCM4 | minichromosome maintenance complex component 4 | 0.030 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.029 | ||
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.029 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.029 | ||
| CUL3 | cullin 3 | 0.028 | ||
| MCM5 | minichromosome maintenance complex component 5 | 0.027 | ||
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.027 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.027 | ||
| MSH3 | mutS homolog 3 (E. coli) | 0.026 | ||
| E2F3 | E2F transcription factor 3 | 0.026 | ||
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.026 | ||
| FOXM1 | forkhead box M1 | 0.026 | ||
| MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.025 | ||
| PAX3 | paired box 3 | 0.025 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.024 | ||
| ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.024 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.024 | ||
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.024 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.024 | Human | |
| TRIM27 | tripartite motif containing 27 | 0.023 | ||
| AGXT2 | alanine--glyoxylate aminotransferase 2 | 0.023 | ||
| BTBD2 | BTB (POZ) domain containing 2 | 0.023 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.023 | Human | |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.023 | ||
| PURA | purine-rich element binding protein A | 0.023 | ||
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.023 | ||
| TOP1 | topoisomerase (DNA) I | 0.023 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.023 | ||
| LRR1 | leucine rich repeat protein 1 | 0.023 | ||
| MED18 | mediator complex subunit 18 | 0.022 | ||
| FOSL1 | FOS-like antigen 1 | 0.022 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.022 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.022 | ||
| PMF1 | polyamine-modulated factor 1 | 0.022 | ||
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.022 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.021 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.021 | ||
| RMI1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) | 0.021 | ||
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.021 | ||
| TCF12 | transcription factor 12 | 0.021 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.021 | ||
| SPRR2A | small proline-rich protein 2A | 0.020 | ||
| MARCKSL1 | MARCKS-like 1 | 0.020 | ||
| USP42 | ubiquitin specific peptidase 42 | 0.020 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.019 | Fly | |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.019 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.019 | ||
| SFN | stratifin | 0.019 | ||
| ERCC4 | excision repair cross-complementing rodent repair deficiency, complementation group 4 | 0.019 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.019 | ||
| PRMT1 | protein arginine methyltransferase 1 | 0.019 | ||
| SSRP1 | structure specific recognition protein 1 | 0.019 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.018 | ||
| BTRC | beta-transducin repeat containing | 0.018 | ||
| VPRBP | Vpr (HIV-1) binding protein | 0.018 | ||
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.018 | ||
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.018 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.018 | ||
| SATB2 | SATB homeobox 2 | 0.018 | ||
| HBP1 | HMG-box transcription factor 1 | 0.017 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.017 | ||
| DEK | DEK oncogene | 0.017 | ||
| POLE3 | polymerase (DNA directed), epsilon 3 (p17 subunit) | 0.017 | ||
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.017 | ||
| CCNH | cyclin H | 0.017 | ||
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.017 | ||
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.017 | ||
| HDGF | hepatoma-derived growth factor | 0.017 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.017 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.017 | ||
| RBM12 | RNA binding motif protein 12 | 0.017 | ||
| FOXD3 | forkhead box D3 | 0.016 | ||
| TELO2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.016 | ||
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.016 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.016 | ||
| KIF5B | kinesin family member 5B | 0.016 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.016 | ||
| BTG2 | BTG family, member 2 | 0.016 | ||
| UNG | uracil-DNA glycosylase | 0.016 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.016 | ||
| FANCC | Fanconi anemia, complementation group C | 0.016 | ||
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.015 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.015 | ||
| MED13 | mediator complex subunit 13 | 0.015 | ||
| RRM2 | ribonucleotide reductase M2 | 0.015 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.015 | ||
| WT1 | Wilms tumor 1 | 0.015 | ||
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | 0.015 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.015 | ||
| AURKB | aurora kinase B | 0.015 | ||
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.015 | ||
| TXN | thioredoxin | 0.015 | ||
| OCIAD1 | OCIA domain containing 1 | 0.015 | ||
| E2F5 | E2F transcription factor 5, p130-binding | 0.015 | ||
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.015 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.015 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.015 | Mouse Fly | |
| CDCA4 | cell division cycle associated 4 | 0.015 | ||
| POLH | polymerase (DNA directed), eta | 0.015 | ||
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.014 | ||
| RPAP3 | RNA polymerase II associated protein 3 | 0.014 | ||
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.014 | ||
| MED13L | mediator complex subunit 13-like | 0.014 | ||
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.014 | ||
| SUZ12 | suppressor of zeste 12 homolog (Drosophila) | 0.014 | ||
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.014 | ||
| MSH5 | mutS homolog 5 (E. coli) | 0.014 | ||
| TFCP2 | transcription factor CP2 | 0.014 | ||
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.014 | ||
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.014 | Fly | |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.014 | ||
| RPA3 | replication protein A3, 14kDa | 0.013 | ||
| BBS2 | Bardet-Biedl syndrome 2 | 0.013 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.013 | ||
| MED20 | mediator complex subunit 20 | 0.013 | ||
| AXIN1 | axin 1 | 0.013 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.013 | ||
| TK1 | thymidine kinase 1, soluble | 0.013 | ||
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.013 | ||
| CCNB2 | cyclin B2 | 0.013 | ||
| CCNA1 | cyclin A1 | 0.013 | ||
| RBBP5 | retinoblastoma binding protein 5 | 0.013 | ||
| IER2 | immediate early response 2 | 0.013 | ||
| MKRN1 | makorin ring finger protein 1 | 0.013 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.013 | ||
| HLTF | helicase-like transcription factor | 0.013 | ||
| ARRB2 | arrestin, beta 2 | 0.013 | ||
| XPO1 | exportin 1 (CRM1 homolog, yeast) | 0.013 | ||
| LIN9 | lin-9 homolog (C. elegans) | 0.013 | ||
| COPS7B | COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) | 0.013 | ||
| MCM3 | minichromosome maintenance complex component 3 | 0.013 | Fly | |
| TUBB | tubulin, beta | 0.013 | ||
| SATB1 | SATB homeobox 1 | 0.013 | ||
| SMAD2 | SMAD family member 2 | 0.013 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.013 | ||
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.012 | ||
| DONSON | downstream neighbor of SON | 0.012 | ||
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.012 | ||
| CDK14 | cyclin-dependent kinase 14 | 0.012 | ||
| RDBP | RD RNA binding protein | 0.012 | ||
| SMAD4 | SMAD family member 4 | 0.012 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.012 | ||
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.012 | ||
| CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.012 | ||
| ASNSD1 | asparagine synthetase domain containing 1 | 0.012 | ||
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.012 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.012 | ||
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.012 | ||
| TRIM28 | tripartite motif containing 28 | 0.012 | ||
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.011 | ||
| MATR3 | matrin 3 | 0.011 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.011 | ||
| HDAC4 | histone deacetylase 4 | 0.011 | ||
| BTBD7 | BTB (POZ) domain containing 7 | 0.011 | ||
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | 0.011 | ||
| HMGA2 | high mobility group AT-hook 2 | 0.011 | ||
| TMPO | thymopoietin | 0.011 | ||
| AHR | aryl hydrocarbon receptor | 0.011 | ||
| CARD16 | caspase recruitment domain family, member 16 | 0.011 | ||
| FEN1 | flap structure-specific endonuclease 1 | 0.011 | ||
| PRMT2 | protein arginine methyltransferase 2 | 0.011 | ||
| SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.011 | ||
| ANXA4 | annexin A4 | 0.011 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.011 | ||
| SEPT7 | septin 7 | 0.011 | ||
| FMR1 | fragile X mental retardation 1 | 0.011 | ||
| NUCB2 | nucleobindin 2 | 0.011 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.011 | ||
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.011 | ||
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) | 0.011 | ||
| CDC25B | cell division cycle 25 homolog B (S. pombe) | 0.011 | ||
| MED14 | mediator complex subunit 14 | 0.011 | ||
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.011 | ||
| KDM5B | lysine (K)-specific demethylase 5B | 0.011 | ||
| FDXR | ferredoxin reductase | 0.010 | ||
| NLK | nemo-like kinase | 0.010 | ||
| COBRA1 | cofactor of BRCA1 | 0.010 | ||
| RECQL4 | RecQ protein-like 4 | 0.010 | ||
| MYCBP | c-myc binding protein | 0.010 | ||
| ASF1B | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.010 | ||
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.010 | ||
| S100A4 | S100 calcium binding protein A4 | 0.010 | ||
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.010 | ||
| KRT6C | keratin 6C | 0.010 | ||
| BIRC6 | baculoviral IAP repeat containing 6 | 0.010 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.010 | ||
| SMAD1 | SMAD family member 1 | 0.010 | ||
| EP300 | E1A binding protein p300 | 0.010 | ||
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.010 | ||
| BBS4 | Bardet-Biedl syndrome 4 | 0.010 |