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Mus musculus

30 genes annotated in mouse

necrotic cell death

A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "necrotic cell death"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "necrotic cell death" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.935
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.925
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.914
Trp53	transformation related protein 53	0.853
Traf2	TNF receptor-associated factor 2	0.851
Pten	phosphatase and tensin homolog	0.844
Ikbkg	inhibitor of kappaB kinase gamma	0.753
Bak1	BCL2-antagonist/killer 1	0.746	Mouse
Casp8	caspase 8	0.713
Stat2	signal transducer and activator of transcription 2	0.659
Sfn	stratifin	0.626
Atf2	activating transcription factor 2	0.610
Itch	itchy, E3 ubiquitin protein ligase	0.579
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.577
Fadd	Fas (TNFRSF6)-associated via death domain	0.550
Cd19	CD19 antigen	0.547
Traf6	TNF receptor-associated factor 6	0.545	Mouse
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.544
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.538
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.481
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.453
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.431
Cyld	cylindromatosis (turban tumor syndrome)	0.414
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.403
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.387
Capns1	calpain, small subunit 1	0.375
Pycard	PYD and CARD domain containing	0.361
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.334
Birc3	baculoviral IAP repeat-containing 3	0.329
Snap25	synaptosomal-associated protein 25	0.301
Ctsb	cathepsin B	0.295
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.275
Gbp5	guanylate binding protein 5	0.240
Flii	flightless I homolog (Drosophila)	0.233
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.227
Rnf31	ring finger protein 31	0.223
Rhog	ras homolog gene family, member G	0.218
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.211	Mouse
Il10	interleukin 10	0.197
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.195
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.184
Cxcl13	chemokine (C-X-C motif) ligand 13	0.177
Trp63	transformation related protein 63	0.167	Mouse
Ifng	interferon gamma	0.164
Mvp	major vault protein	0.160
Ripk3	receptor-interacting serine-threonine kinase 3	0.159
Sh3gl2	SH3-domain GRB2-like 2	0.158	Worm
Mapk14	mitogen-activated protein kinase 14	0.154	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.152
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.150
Cd40	CD40 antigen	0.150
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.149
Il7	interleukin 7	0.145
Mapkapk2	MAP kinase-activated protein kinase 2	0.145
Hccs	holocytochrome c synthetase	0.141
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.139	Mouse
Ctsl	cathepsin L	0.137
Aim2	absent in melanoma 2	0.132
Sesn2	sestrin 2	0.132
Card11	caspase recruitment domain family, member 11	0.131
Stat6	signal transducer and activator of transcription 6	0.130
Nlrp3	NLR family, pyrin domain containing 3	0.126
Igh	immunoglobulin heavy chain complex	0.123
Hr	hairless	0.121
Lag3	lymphocyte-activation gene 3	0.120
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.119
Vamp2	vesicle-associated membrane protein 2	0.117
Bax	BCL2-associated X protein	0.115
Ikbkb	inhibitor of kappaB kinase beta	0.114
Atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.112
Icos	inducible T-cell co-stimulator	0.110
Stim2	stromal interaction molecule 2	0.104
Smad3	MAD homolog 3 (Drosophila)	0.097
Aicda	activation-induced cytidine deaminase	0.097
Mdm2	transformed mouse 3T3 cell double minute 2	0.095
Mx1	myxovirus (influenza virus) resistance 1	0.095
Lta	lymphotoxin A	0.095	Mouse
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.094
Batf	basic leucine zipper transcription factor, ATF-like	0.094
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.093
Dnm1	dynamin 1	0.089	Worm
Coro1b	coronin, actin binding protein 1B	0.089
Irf8	interferon regulatory factor 8	0.088	Mouse
Arpc4	actin related protein 2/3 complex, subunit 4	0.088
Il2rb	interleukin 2 receptor, beta chain	0.088
Trp73	transformation related protein 73	0.088	Mouse
Tlr4	toll-like receptor 4	0.085
Tcf3	transcription factor 3	0.083
Ltbr	lymphotoxin B receptor	0.082
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.081
Ltb	lymphotoxin B	0.081
Trim21	tripartite motif-containing 21	0.079
Eya2	eyes absent 2 homolog (Drosophila)	0.077
Skil	SKI-like	0.077
Uba7	ubiquitin-like modifier activating enzyme 7	0.076
Mdm4	transformed mouse 3T3 cell double minute 4	0.076
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.074
Necap2	NECAP endocytosis associated 2	0.073
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.071
Xiap	X-linked inhibitor of apoptosis	0.070	Mouse
Lamp1	lysosomal-associated membrane protein 1	0.069
Sharpin	SHANK-associated RH domain interacting protein	0.068	Mouse
Tox	thymocyte selection-associated high mobility group box	0.068
Mapk9	mitogen-activated protein kinase 9	0.067	Mouse
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.065
Casp7	caspase 7	0.065	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.063
Hif1a	hypoxia inducible factor 1, alpha subunit	0.063
Agtr1a	angiotensin II receptor, type 1a	0.061
Arnt	aryl hydrocarbon receptor nuclear translocator	0.061
Syngr2	synaptogyrin 2	0.061
Irf1	interferon regulatory factor 1	0.060	Mouse
Tgfb1	transforming growth factor, beta 1	0.059
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.059
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.058
Kif5a	kinesin family member 5A	0.057	Worm
Capn1	calpain 1	0.056	Worm
Myd88	myeloid differentiation primary response gene 88	0.053
Dok1	docking protein 1	0.053
Id2	inhibitor of DNA binding 2	0.051
Dlg4	discs, large homolog 4 (Drosophila)	0.051
Wbp2	WW domain binding protein 2	0.051
Gabarap	gamma-aminobutyric acid receptor associated protein	0.050	Worm
Prmt1	protein arginine N-methyltransferase 1	0.050
Il2ra	interleukin 2 receptor, alpha chain	0.050
Ncoa2	nuclear receptor coactivator 2	0.049
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.049
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.048
Ap2m1	adaptor protein complex AP-2, mu1	0.047	Worm
Map2k4	mitogen-activated protein kinase kinase 4	0.047
Lrrk2	leucine-rich repeat kinase 2	0.047
Ptgs2	prostaglandin-endoperoxide synthase 2	0.046
Ap2a2	adaptor protein complex AP-2, alpha 2 subunit	0.046
Myo6	myosin VI	0.046
Cd80	CD80 antigen	0.045
Tor3a	torsin family 3, member A	0.045
Mavs	mitochondrial antiviral signaling protein	0.045
Ikzf3	IKAROS family zinc finger 3	0.044
Spnb3	spectrin beta 3	0.044
Pfn1	profilin 1	0.043
Aup1	ancient ubiquitous protein 1	0.042
Il4ra	interleukin 4 receptor, alpha	0.042
Cfl1	cofilin 1, non-muscle	0.041
Bid	BH3 interacting domain death agonist	0.041
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.041
Il4	interleukin 4	0.040
Mfn2	mitofusin 2	0.040
Cd28	CD28 antigen	0.040
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.040
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.040
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.039
Ubc	ubiquitin C	0.039
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.039
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.038
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.038
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.037
Ctsd	cathepsin D	0.037	Worm
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.037
Ikzf1	IKAROS family zinc finger 1	0.036
Per3	period homolog 3 (Drosophila)	0.036
Ticam1	toll-like receptor adaptor molecule 1	0.035
Rb1cc1	RB1-inducible coiled-coil 1	0.035
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.035
Cxcr5	chemokine (C-X-C motif) receptor 5	0.035
Rara	retinoic acid receptor, alpha	0.035
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.034
Dtna	dystrobrevin alpha	0.034
Syp	synaptophysin	0.034
Col19a1	collagen, type XIX, alpha 1	0.033
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.032
Kdm6a	4lysine (K)-specific demethylase 6A	0.032
Bcl2	B-cell leukemia/lymphoma 2	0.032	Mouse
AW112010	expressed sequence AW112010	0.032
Foxp3	forkhead box P3	0.032
Slurp1	secreted Ly6/Plaur domain containing 1	0.031
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.031
Wdr26	WD repeat domain 26	0.031
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.031
Oas3	2'-5' oligoadenylate synthetase 3	0.031
Ptp4a2	protein tyrosine phosphatase 4a2	0.030
Stat5b	signal transducer and activator of transcription 5B	0.030
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.030
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.029
Mx2	myxovirus (influenza virus) resistance 2	0.029
Pdcd1	programmed cell death 1	0.029
Pml	promyelocytic leukemia	0.028
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.028
Cd160	CD160 antigen	0.028
Pdcd1lg2	programmed cell death 1 ligand 2	0.028
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.028
Plxna1	plexin A1	0.028
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.028
Scn1b	sodium channel, voltage-gated, type I, beta	0.027
Ttn	titin	0.027
Il27ra	interleukin 27 receptor, alpha	0.027
Ifnar1	interferon (alpha and beta) receptor 1	0.027
Ly96	lymphocyte antigen 96	0.027
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.027
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.027
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.027
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.027
Znfx1	zinc finger, NFX1-type containing 1	0.027
Gopc	golgi associated PDZ and coiled-coil motif containing	0.026
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.026
Diablo	diablo homolog (Drosophila)	0.026
Mtmr1	myotubularin related protein 1	0.026
Chuk	conserved helix-loop-helix ubiquitous kinase	0.026
Gzmb	granzyme B	0.026	Rat
Pou2af1	POU domain, class 2, associating factor 1	0.026
Jag2	jagged 2	0.026
Zbp1	Z-DNA binding protein 1	0.025
Il18	interleukin 18	0.025
Rarg	retinoic acid receptor, gamma	0.025
Sepx1	selenoprotein X 1	0.025
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.024
Slc4a7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	0.024
Zfp40	zinc finger protein 40	0.024
Nab1	Ngfi-A binding protein 1	0.024
Pfn2	profilin 2	0.024
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.024
Prss30	protease, serine, 30	0.024
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.023
Map2k3	mitogen-activated protein kinase kinase 3	0.023
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.023
Frmd5	FERM domain containing 5	0.023
Cd86	CD86 antigen	0.023
Mef2a	myocyte enhancer factor 2A	0.023
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.023
Klc1	kinesin light chain 1	0.022
Gba	glucosidase, beta, acid	0.022
Casp3	caspase 3	0.022	Mouse
Aim1	absent in melanoma 1	0.022
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.022
Lamp2	lysosomal-associated membrane protein 2	0.022
Cflar	CASP8 and FADD-like apoptosis regulator	0.022
Cd2ap	CD2-associated protein	0.022
Stx1a	syntaxin 1A (brain)	0.022
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.022
Mlkl	mixed lineage kinase domain-like	0.022
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.022
Ctsw	cathepsin W	0.022
Gbp1	guanylate binding protein 1	0.022
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.022
Pkm2	pyruvate kinase, muscle	0.022
Zbtb24	zinc finger and BTB domain containing 24	0.022
Kif5c	kinesin family member 5C	0.022	Worm
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.021
Stxbp3a	syntaxin binding protein 3A	0.021
Traf1	TNF receptor-associated factor 1	0.021	Mouse
Camk4	calcium/calmodulin-dependent protein kinase IV	0.021
Mapk11	mitogen-activated protein kinase 11	0.021	Mouse
Tmem173	transmembrane protein 173	0.021
Ahr	aryl-hydrocarbon receptor	0.020
Nphs2	nephrosis 2 homolog, podocin (human)	0.020
Naip2	NLR family, apoptosis inhibitory protein 2	0.020
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.020
Tbk1	TANK-binding kinase 1	0.020
Mapk8	mitogen-activated protein kinase 8	0.020
Lrp10	low-density lipoprotein receptor-related protein 10	0.020
Pdcd6ip	programmed cell death 6 interacting protein	0.020
Socs1	suppressor of cytokine signaling 1	0.020
Gbp7	guanylate binding protein 7	0.020
Rab5b	RAB5B, member RAS oncogene family	0.020
Pkp3	plakophilin 3	0.020
Wwox	WW domain-containing oxidoreductase	0.020
Med1	mediator complex subunit 1	0.020
Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2	0.020
Itgal	integrin alpha L	0.019
Dmpk	dystrophia myotonica-protein kinase	0.019
A230046K03Rik	RIKEN cDNA A230046K03 gene	0.019
Il2rg	interleukin 2 receptor, gamma chain	0.019
Sipa1	signal-induced proliferation associated gene 1	0.019
Dsg4	desmoglein 4	0.019
Samhd1	SAM domain and HD domain, 1	0.019
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.019
Aff1	AF4/FMR2 family, member 1	0.019
Cd96	CD96 antigen	0.019
Pld3	phospholipase D family, member 3	0.019
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.018
Prr13	proline rich 13	0.018
Myo1c	myosin IC	0.018
Huwe1	HECT, UBA and WWE domain containing 1	0.018
Smad5	MAD homolog 5 (Drosophila)	0.018
Pkia	protein kinase inhibitor, alpha	0.018
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.018
Cst3	cystatin C	0.018
Zfp53	zinc finger protein 53	0.018
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.018
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.018
Map2k7	mitogen-activated protein kinase kinase 7	0.018
Rps6kb2	ribosomal protein S6 kinase, polypeptide 2	0.017
Sh2b3	SH2B adaptor protein 3	0.017
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.017
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.017
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.017
Cdcp1	CUB domain containing protein 1	0.017
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.017
Tcte1	t-complex-associated testis expressed 1	0.017
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.017
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.017
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.017
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.017
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.017
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.017
Cd5	CD5 antigen	0.017
Ccl4	chemokine (C-C motif) ligand 4	0.017
Ncoa3	nuclear receptor coactivator 3	0.017
Rtn2	reticulon 2 (Z-band associated protein)	0.017
Inpp5j	inositol polyphosphate 5-phosphatase J	0.017
Dbnl	drebrin-like	0.017
Pla2g4f	phospholipase A2, group IVF	0.017
Btg1	B-cell translocation gene 1, anti-proliferative	0.017
Rbl1	retinoblastoma-like 1 (p107)	0.017
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.017
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.017
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.016
Casp1	caspase 1	0.016
Jak3	Janus kinase 3	0.016
Tmem38a	transmembrane protein 38A	0.016
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.016
Rabac1	Rab acceptor 1 (prenylated)	0.016
Pls3	plastin 3 (T-isoform)	0.016
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.016
Sez6l	seizure related 6 homolog like	0.016
Il12rb1	interleukin 12 receptor, beta 1	0.016
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.016
Mfsd5	major facilitator superfamily domain containing 5	0.016
Ache	acetylcholinesterase	0.016
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.015
Plxna3	plexin A3	0.015
Ttc7	tetratricopeptide repeat domain 7	0.015
Rnasek	ribonuclease, RNase K	0.015
Shkbp1	Sh3kbp1 binding protein 1	0.015
Sh2d2a	SH2 domain protein 2A	0.015
Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	0.015
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.015
Mlf2	myeloid leukemia factor 2	0.015
Cst7	cystatin F (leukocystatin)	0.015
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.015
Tradd	TNFRSF1A-associated via death domain	0.015
BC006779	cDNA sequence BC006779	0.015
Fkbp8	FK506 binding protein 8	0.015
Ube2v1	ubiquitin-conjugating enzyme E2 variant 1	0.015
Rxra	retinoid X receptor alpha	0.015
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.015
Mov10	Moloney leukemia virus 10	0.015
Smek2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	0.015
Usp18	ubiquitin specific peptidase 18	0.015
Il12b	interleukin 12b	0.015
Adrbk1	adrenergic receptor kinase, beta 1	0.015
Zbtb7b	zinc finger and BTB domain containing 7B	0.015
Itgb4	integrin beta 4	0.015
Gsdmd	gasdermin D	0.014
Aes	amino-terminal enhancer of split	0.014
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.014
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.014
Gipc1	GIPC PDZ domain containing family, member 1	0.014
Sult4a1	sulfotransferase family 4A, member 1	0.014
Gsdma3	gasdermin A3	0.014
Rab4b	RAB4B, member RAS oncogene family	0.014
Phka1	phosphorylase kinase alpha 1	0.014
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.014
Mtmr7	myotubularin related protein 7	0.014
Pyhin1	pyrin and HIN domain family, member 1	0.014
Cxcl9	chemokine (C-X-C motif) ligand 9	0.014
Trim30d	tripartite motif-containing 30D	0.014
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.014
Eps15	epidermal growth factor receptor pathway substrate 15	0.014
Sh3bp2	SH3-domain binding protein 2	0.014
Trim30a	tripartite motif-containing 30A	0.014
Tapbpl	TAP binding protein-like	0.014
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.014
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.014
Gripap1	GRIP1 associated protein 1	0.014
Ids	iduronate 2-sulfatase	0.013
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.013
Ciita	class II transactivator	0.013
Irf6	interferon regulatory factor 6	0.013	Mouse
Alox8	arachidonate 8-lipoxygenase	0.013
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.013	Mouse
Hdac7	histone deacetylase 7	0.013
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.013
Il21r	interleukin 21 receptor	0.013
Irak3	interleukin-1 receptor-associated kinase 3	0.013
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.013
Epsti1	epithelial stromal interaction 1 (breast)	0.013
Ccl1	chemokine (C-C motif) ligand 1	0.013
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.013
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.013
Mid2	midline 2	0.013
Pthlh	parathyroid hormone-like peptide	0.013
Wnt10a	wingless related MMTV integration site 10a	0.013
Mcl1	myeloid cell leukemia sequence 1	0.013	Mouse
Adcy2	adenylate cyclase 2	0.013
Mapt	microtubule-associated protein tau	0.013
Rsad2	radical S-adenosyl methionine domain containing 2	0.013
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.013
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Gnao1	guanine nucleotide binding protein, alpha O	0.013
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.013
Rab5c	RAB5C, member RAS oncogene family	0.012
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.012
Otp	orthopedia homolog (Drosophila)	0.012
Ifngr1	interferon gamma receptor 1	0.012
Htra2	HtrA serine peptidase 2	0.012
Rab1b	RAB1B, member RAS oncogene family	0.012
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.012
Ryr1	ryanodine receptor 1, skeletal muscle	0.012
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.012
Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1	0.012
Traf3	TNF receptor-associated factor 3	0.012	Mouse
Nat15	N-acetyltransferase 15 (GCN5-related, putative)	0.012
H2afx	H2A histone family, member X	0.012
Tubb5	tubulin, beta 5	0.012
H2-DMa	histocompatibility 2, class II, locus DMa	0.012
Rasa4	RAS p21 protein activator 4	0.012
Trafd1	TRAF type zinc finger domain containing 1	0.012
Syn2	synapsin II	0.012
Mab21l2	mab-21-like 2 (C. elegans)	0.012
Xdh	xanthine dehydrogenase	0.012
Wrn	Werner syndrome homolog (human)	0.012
Triobp	TRIO and F-actin binding protein	0.012
Gm13290	predicted gene 13290	0.012
Ar	androgen receptor	0.012
Trim25	tripartite motif-containing 25	0.012
Hap1	huntingtin-associated protein 1	0.012
Il6	interleukin 6	0.012
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.012
Irf4	interferon regulatory factor 4	0.012	Mouse
Itga4	integrin alpha 4	0.012
Ccnb2	cyclin B2	0.012
Ate1	arginyltransferase 1	0.012
Klc2	kinesin light chain 2	0.012
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.012
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.012	Worm
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.012
Gja1	gap junction protein, alpha 1	0.012
Lrrc58	leucine rich repeat containing 58	0.012
Fgl2	fibrinogen-like protein 2	0.012
Klf4	Kruppel-like factor 4 (gut)	0.012
Tyro3	TYRO3 protein tyrosine kinase 3	0.012
Vill	villin-like	0.012
Gzmc	granzyme C	0.012
Parp14	poly (ADP-ribose) polymerase family, member 14	0.012
Slamf8	SLAM family member 8	0.011
Ifi44	interferon-induced protein 44	0.011
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.011
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.011
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
Vasp	vasodilator-stimulated phosphoprotein	0.011
Ms4a10	membrane-spanning 4-domains, subfamily A, member 10	0.011
Stxbp2	syntaxin binding protein 2	0.011
Bcl6	B-cell leukemia/lymphoma 6	0.011
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.011
Bbc3	BCL2 binding component 3	0.011
Wbp1	WW domain binding protein 1	0.011
Cxcl2	chemokine (C-X-C motif) ligand 2	0.011
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.011	Mouse
Dtnb	dystrobrevin, beta	0.011
Vegfb	vascular endothelial growth factor B	0.011
Impad1	inositol monophosphatase domain containing 1	0.011
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.011
Irgm1	immunity-related GTPase family M member 1	0.011
Zfp106	zinc finger protein 106	0.011
Pfkm	phosphofructokinase, muscle	0.011
Ube2l3	ubiquitin-conjugating enzyme E2L 3	0.011
Bcl2l1	BCL2-like 1	0.011	Mouse
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.011
Plekho2	pleckstrin homology domain containing, family O member 2	0.011
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.011
Vdr	vitamin D receptor	0.011
Mapk12	mitogen-activated protein kinase 12	0.011	Mouse
Gsta4	glutathione S-transferase, alpha 4	0.011
Pvalb	parvalbumin	0.011
Zfp445	zinc finger protein 445	0.011
Rnf208	ring finger protein 208	0.011
Gars	glycyl-tRNA synthetase	0.011
Csk	c-src tyrosine kinase	0.011
Pik3c3	phosphoinositide-3-kinase, class 3	0.011
Hsf4	heat shock transcription factor 4	0.010
Mmp17	matrix metallopeptidase 17	0.010
Slamf7	SLAM family member 7	0.010
Naip6	NLR family, apoptosis inhibitory protein 6	0.010	Mouse
Sertad3	SERTA domain containing 3	0.010
Rab25	RAB25, member RAS oncogene family	0.010
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.010
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.010
1810030J14Rik	RIKEN cDNA 1810030J14 gene	0.010
Rac1	RAS-related C3 botulinum substrate 1	0.010
Prnp	prion protein	0.010
Irf7	interferon regulatory factor 7	0.010	Mouse
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.010
Pgd	phosphogluconate dehydrogenase	0.010
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.010
Phlda3	pleckstrin homology-like domain, family A, member 3	0.010
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.010
Myh9	myosin, heavy polypeptide 9, non-muscle	0.010
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.010
Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	0.010
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.010
Peli1	pellino 1	0.010
Oas2	2'-5' oligoadenylate synthetase 2	0.010
Ccnl1	cyclin L1	0.010
Dnase1l2	deoxyribonuclease 1-like 2	0.010
Ttc7b	tetratricopeptide repeat domain 7B	0.010
Ehd4	EH-domain containing 4	0.010	Worm