IMP

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Homo sapiens

40 genes annotated in human

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.

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Gene Predictions

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Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" (in gray)

Name	Description	Probability	Func Analog Organism
IL4R	interleukin 4 receptor	0.966	Mouse
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.951	Mouse
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.880
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.877
NOTCH1	notch 1	0.773
TRAF1	TNF receptor-associated factor 1	0.722	Human
HLA-A	major histocompatibility complex, class I, A	0.716
HLA-C	major histocompatibility complex, class I, C	0.666	Human
B2M	beta-2-microglobulin	0.643	Mouse
CD80	CD80 molecule	0.595
HLA-DMB	major histocompatibility complex, class II, DM beta	0.574
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.564
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.563
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.563
IL2RG	interleukin 2 receptor, gamma	0.540
TRAF6	TNF receptor-associated factor 6	0.531
CCL5	chemokine (C-C motif) ligand 5	0.512	Human
BTN3A2	butyrophilin, subfamily 3, member A2	0.493
HLA-G	major histocompatibility complex, class I, G	0.476	Human
CCR5	chemokine (C-C motif) receptor 5	0.475
CD40	CD40 molecule, TNF receptor superfamily member 5	0.474	Mouse Rat
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.446
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.442
CCL4	chemokine (C-C motif) ligand 4	0.428	Human
LAPTM5	lysosomal protein transmembrane 5	0.425
C1QA	complement component 1, q subcomponent, A chain	0.415	Mouse
BTN3A1	butyrophilin, subfamily 3, member A1	0.405	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.402
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.381
HLA-B	major histocompatibility complex, class I, B	0.362
LCK	lymphocyte-specific protein tyrosine kinase	0.352
HLA-F	major histocompatibility complex, class I, F	0.346	Human
HLA-E	major histocompatibility complex, class I, E	0.342	Human
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.328	Human
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.308
BIRC3	baculoviral IAP repeat containing 3	0.290
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.272
CALCOCO2	calcium binding and coiled-coil domain 2	0.270
CXCL9	chemokine (C-X-C motif) ligand 9	0.256
TNF	tumor necrosis factor	0.255
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.229
APLF	aprataxin and PNKP like factor	0.220
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.220
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.211
NRP1	neuropilin 1	0.211
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.202
CCR7	chemokine (C-C motif) receptor 7	0.199
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	0.197	Mouse
CCL8	chemokine (C-C motif) ligand 8	0.196	Human
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.185
BTN3A3	butyrophilin, subfamily 3, member A3	0.183
IL2RB	interleukin 2 receptor, beta	0.179
IL4	interleukin 4	0.177
DLG1	discs, large homolog 1 (Drosophila)	0.172	Mouse
IRF4	interferon regulatory factor 4	0.172	Mouse
CD2	CD2 molecule	0.171
BCL3	B-cell CLL/lymphoma 3	0.170	Mouse
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.167	Mouse
GRAP2	GRB2-related adaptor protein 2	0.165
CD48	CD48 molecule	0.160
BRCA1	breast cancer 1, early onset	0.153
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.153
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.151
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.150
FASLG	Fas ligand (TNF superfamily, member 6)	0.146
C1QC	complement component 1, q subcomponent, C chain	0.137	Zebrafish
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.129
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.126
ICAM1	intercellular adhesion molecule 1	0.124	Mouse
CD86	CD86 molecule	0.123	Human
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.122
SOCS3	suppressor of cytokine signaling 3	0.112
TRAF2	TNF receptor-associated factor 2	0.106
MDC1	mediator of DNA-damage checkpoint 1	0.104
IL8	interleukin 8	0.099
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.098
SH2D2A	SH2 domain containing 2A	0.096
CD22	CD22 molecule	0.095
CCR1	chemokine (C-C motif) receptor 1	0.094
CARD11	caspase recruitment domain family, member 11	0.093
SIGLEC7	sialic acid binding Ig-like lectin 7	0.092
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.090
IFNG	interferon, gamma	0.086
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.085
HDAC9	histone deacetylase 9	0.083
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.083
IL6R	interleukin 6 receptor	0.082
SLC15A3	solute carrier family 15, member 3	0.081
PILRA	paired immunoglobin-like type 2 receptor alpha	0.079
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.079	Mouse
TAPBP	TAP binding protein (tapasin)	0.079
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.079
SYK	spleen tyrosine kinase	0.077
IRAK1	interleukin-1 receptor-associated kinase 1	0.077
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.076
IL10	interleukin 10	0.076
VAMP4	vesicle-associated membrane protein 4	0.075
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.074
ZBP1	Z-DNA binding protein 1	0.073
NOTCH3	notch 3	0.072
CFH	complement factor H	0.067
CFLAR	CASP8 and FADD-like apoptosis regulator	0.065
IL10RA	interleukin 10 receptor, alpha	0.064
C1QB	complement component 1, q subcomponent, B chain	0.063
BCL10	B-cell CLL/lymphoma 10	0.061	Mouse
TGIF1	TGFB-induced factor homeobox 1	0.060
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.060
LIG4	ligase IV, DNA, ATP-dependent	0.060	Mouse
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.059
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.059
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.059	Human
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.059	Mouse
SNAP23	synaptosomal-associated protein, 23kDa	0.058
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.058
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.058
BTN2A2	butyrophilin, subfamily 2, member A2	0.058	Human
HK3	hexokinase 3 (white cell)	0.057
NOD2	nucleotide-binding oligomerization domain containing 2	0.056
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.056
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.054
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.054
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.054
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.051
SRGN	serglycin	0.051
CST7	cystatin F (leukocystatin)	0.050
CYBB	cytochrome b-245, beta polypeptide	0.050
SLAMF1	signaling lymphocytic activation molecule family member 1	0.050
IL21R	interleukin 21 receptor	0.049
FAS	Fas (TNF receptor superfamily, member 6)	0.049	Mouse
CCL22	chemokine (C-C motif) ligand 22	0.048	Human
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.048	Mouse
MSH3	mutS homolog 3 (E. coli)	0.047
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.047
C2	complement component 2	0.046
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.046
CXCL10	chemokine (C-X-C motif) ligand 10	0.045
SLAMF7	SLAM family member 7	0.044
CD33	CD33 molecule	0.043
CCL7	chemokine (C-C motif) ligand 7	0.043	Human
CXCR6	chemokine (C-X-C motif) receptor 6	0.043
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	0.043	Mouse
TP53BP1	tumor protein p53 binding protein 1	0.042
CCL19	chemokine (C-C motif) ligand 19	0.042	Human Mouse
IL32	interleukin 32	0.041
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.041
TANK	TRAF family member-associated NFKB activator	0.040
PVRL4	poliovirus receptor-related 4	0.039
HCK	hemopoietic cell kinase	0.039
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.039
IRF1	interferon regulatory factor 1	0.039
CD8B	CD8b molecule	0.039
THOC5	THO complex 5	0.038
ENG	endoglin	0.038
ADAM17	ADAM metallopeptidase domain 17	0.037	Mouse
STAT4	signal transducer and activator of transcription 4	0.037
TYMP	thymidine phosphorylase	0.037
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.037	Mouse
CD247	CD247 molecule	0.036
IL2RA	interleukin 2 receptor, alpha	0.036
MARCO	macrophage receptor with collagenous structure	0.036
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.036
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.036	Mouse
CCR4	chemokine (C-C motif) receptor 4	0.035
ZC3H12A	zinc finger CCCH-type containing 12A	0.035
EPAS1	endothelial PAS domain protein 1	0.035
CXCL13	chemokine (C-X-C motif) ligand 13	0.034
SLAMF8	SLAM family member 8	0.034
LGALS3	lectin, galactoside-binding, soluble, 3	0.033
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.033	Human
PLEK	pleckstrin	0.033
CLEC10A	C-type lectin domain family 10, member A	0.033
CCL2	chemokine (C-C motif) ligand 2	0.033	Human
PLXNB2	plexin B2	0.032
FANCD2	Fanconi anemia, complementation group D2	0.032
TRADD	TNFRSF1A-associated via death domain	0.032
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.032
NOTCH2	notch 2	0.032
IL18RAP	interleukin 18 receptor accessory protein	0.032
EPOR	erythropoietin receptor	0.032
CCL11	chemokine (C-C motif) ligand 11	0.032	Human
ZMYND11	zinc finger, MYND-type containing 11	0.032
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.031
CXCL11	chemokine (C-X-C motif) ligand 11	0.031
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.031	Mouse
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.030
IRAK3	interleukin-1 receptor-associated kinase 3	0.030
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.030
SQSTM1	sequestosome 1	0.030
PRF1	perforin 1 (pore forming protein)	0.030
BTN2A1	butyrophilin, subfamily 2, member A1	0.030	Human
PRKCQ	protein kinase C, theta	0.030	Mouse
MLPH	melanophilin	0.029
VSIG4	V-set and immunoglobulin domain containing 4	0.029
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.029
CCL13	chemokine (C-C motif) ligand 13	0.029	Human
CD163	CD163 molecule	0.029
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.029
SMAD3	SMAD family member 3	0.028
MBD4	methyl-CpG binding domain protein 4	0.028
TBX21	T-box 21	0.028	Mouse
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.028
IDE	insulin-degrading enzyme	0.028
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.027
MEF2A	myocyte enhancer factor 2A	0.027
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.027
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.027
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.027
FADD	Fas (TNFRSF6)-associated via death domain	0.026	Mouse
NCF1	neutrophil cytosolic factor 1	0.026
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.026
NKG7	natural killer cell group 7 sequence	0.026
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.026	Human
TRIM38	tripartite motif containing 38	0.026
XCL1	chemokine (C motif) ligand 1	0.025
CXCL2	chemokine (C-X-C motif) ligand 2	0.025
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.025
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.025	Human
MSH6	mutS homolog 6 (E. coli)	0.025	Mouse
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.025
SIRPB1	signal-regulatory protein beta 1	0.025
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.025
ITGB7	integrin, beta 7	0.025
CSF1	colony stimulating factor 1 (macrophage)	0.024
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.024
TARP	TCR gamma alternate reading frame protein	0.024
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.024
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.024
DPP4	dipeptidyl-peptidase 4	0.024
CD38	CD38 molecule	0.024
CCL3	chemokine (C-C motif) ligand 3	0.023	Human
IL13	interleukin 13	0.023	Human
UBASH3B	ubiquitin associated and SH3 domain containing B	0.023
IDO1	indoleamine 2,3-dioxygenase 1	0.023
C9orf89	chromosome 9 open reading frame 89	0.023
CD68	CD68 molecule	0.022
TLR2	toll-like receptor 2	0.022
TRAF3	TNF receptor-associated factor 3	0.022	Human
IL1B	interleukin 1, beta	0.022
PVRL3	poliovirus receptor-related 3	0.022	Human
FPR3	formyl peptide receptor 3	0.022
CD40LG	CD40 ligand	0.022
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.022
USP15	ubiquitin specific peptidase 15	0.022
CD83	CD83 molecule	0.022
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.022
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.021
TFRC	transferrin receptor (p90, CD71)	0.021
CCL20	chemokine (C-C motif) ligand 20	0.021	Human
AOAH	acyloxyacyl hydrolase (neutrophil)	0.021
BATF	basic leucine zipper transcription factor, ATF-like	0.021	Mouse
HCP5	HLA complex P5	0.021
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.021
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.021
MAP1S	microtubule-associated protein 1S	0.021
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.021
BATF2	basic leucine zipper transcription factor, ATF-like 2	0.021
NSF	N-ethylmaleimide-sensitive factor	0.021
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.021
IGSF6	immunoglobulin superfamily, member 6	0.020
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.020	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.020
CMKLR1	chemokine-like receptor 1	0.020
OSMR	oncostatin M receptor	0.020
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.020
CXCR4	chemokine (C-X-C motif) receptor 4	0.020
CCR3	chemokine (C-C motif) receptor 3	0.020
ZNF830	zinc finger protein 830	0.020
CXCR3	chemokine (C-X-C motif) receptor 3	0.020
CCL1	chemokine (C-C motif) ligand 1	0.020	Human
CH25H	cholesterol 25-hydroxylase	0.020
TPP1	tripeptidyl peptidase I	0.020
CSF1R	colony stimulating factor 1 receptor	0.020
PICALM	phosphatidylinositol binding clathrin assembly protein	0.020
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.019	Human
RAD50	RAD50 homolog (S. cerevisiae)	0.019
GADD45B	growth arrest and DNA-damage-inducible, beta	0.019
RUNX3	runt-related transcription factor 3	0.019
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.019
TLR7	toll-like receptor 7	0.019
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.019
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.019
IL18R1	interleukin 18 receptor 1	0.019	Mouse
PLXND1	plexin D1	0.018
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.018
MSR1	macrophage scavenger receptor 1	0.018
NHEJ1	nonhomologous end-joining factor 1	0.018
PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	0.018
SOD2	superoxide dismutase 2, mitochondrial	0.018
CD226	CD226 molecule	0.018
IRF2	interferon regulatory factor 2	0.018
CD300C	CD300c molecule	0.018
H2AFX	H2A histone family, member X	0.018
LGALS9	lectin, galactoside-binding, soluble, 9	0.018	Human
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.018
EBI3	Epstein-Barr virus induced 3	0.018
IL9	interleukin 9	0.017
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.017
CCR2	chemokine (C-C motif) receptor 2	0.017	Mouse
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.017
GNLY	granulysin	0.017
ISG20	interferon stimulated exonuclease gene 20kDa	0.017
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.017
FCAR	Fc fragment of IgA, receptor for	0.017	Human
CD1D	CD1d molecule	0.017	Mouse
FGL2	fibrinogen-like 2	0.017
TREM1	triggering receptor expressed on myeloid cells 1	0.017
TNFRSF17	tumor necrosis factor receptor superfamily, member 17	0.017
ADAMDEC1	ADAM-like, decysin 1	0.017
C3AR1	complement component 3a receptor 1	0.017	Rat
SOCS1	suppressor of cytokine signaling 1	0.017
CIITA	class II, major histocompatibility complex, transactivator	0.017
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.017
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.017
PTAFR	platelet-activating factor receptor	0.016
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.016
KIAA1267	KIAA1267	0.016
IL4I1	interleukin 4 induced 1	0.016
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.016
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.016
ZNF282	zinc finger protein 282	0.016
PML	promyelocytic leukemia	0.016
SH3BP2	SH3-domain binding protein 2	0.016
IFNB1	interferon, beta 1, fibroblast	0.016
ITK	IL2-inducible T-cell kinase	0.016
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.016	Human
TCF4	transcription factor 4	0.016
MR1	major histocompatibility complex, class I-related	0.016	Human
BATF3	basic leucine zipper transcription factor, ATF-like 3	0.016
TRAF5	TNF receptor-associated factor 5	0.016	Human
BTK	Bruton agammaglobulinemia tyrosine kinase	0.016
UBD	ubiquitin D	0.016
C1S	complement component 1, s subcomponent	0.016
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.015
STAB1	stabilin 1	0.015
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.015
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.015
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.015	Mouse
RBBP8	retinoblastoma binding protein 8	0.015
SIGLEC9	sialic acid binding Ig-like lectin 9	0.015
UBA7	ubiquitin-like modifier activating enzyme 7	0.015
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.015
CHIT1	chitinase 1 (chitotriosidase)	0.015
IL7	interleukin 7	0.015
DOK2	docking protein 2, 56kDa	0.015
UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	0.015
SBNO2	strawberry notch homolog 2 (Drosophila)	0.015
RNF8	ring finger protein 8	0.015
CCL23	chemokine (C-C motif) ligand 23	0.015	Human
PBK	PDZ binding kinase	0.015
CTBP2	C-terminal binding protein 2	0.015
MAN2B1	mannosidase, alpha, class 2B, member 1	0.015
OASL	2'-5'-oligoadenylate synthetase-like	0.015
IFI35	interferon-induced protein 35	0.015
CD52	CD52 molecule	0.015
PELI3	pellino homolog 3 (Drosophila)	0.015
ETV7	ets variant 7	0.015
TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	0.014
TRAF3IP3	TRAF3 interacting protein 3	0.014
IL7R	interleukin 7 receptor	0.014	Mouse
PCDH9	protocadherin 9	0.014
CD37	CD37 molecule	0.014
TGFBR1	transforming growth factor, beta receptor 1	0.014
GFI1B	growth factor independent 1B transcription repressor	0.014
IL13RA1	interleukin 13 receptor, alpha 1	0.014
CTSW	cathepsin W	0.014
EPS15	epidermal growth factor receptor pathway substrate 15	0.014
LY86	lymphocyte antigen 86	0.014
TRIM37	tripartite motif containing 37	0.014
LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.014
AQP9	aquaporin 9	0.014
MSC	musculin	0.014
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.014
ATR	ataxia telangiectasia and Rad3 related	0.014
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.014
CREBL2	cAMP responsive element binding protein-like 2	0.014
CTSS	cathepsin S	0.014
TGFB1	transforming growth factor, beta 1	0.014
CD69	CD69 molecule	0.014
CCL17	chemokine (C-C motif) ligand 17	0.014	Human
ING2	inhibitor of growth family, member 2	0.014
PRKCB	protein kinase C, beta	0.014
STC1	stanniocalcin 1	0.014
IRF5	interferon regulatory factor 5	0.014
BCL2A1	BCL2-related protein A1	0.014
CD164	CD164 molecule, sialomucin	0.014
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.013
TRAT1	T cell receptor associated transmembrane adaptor 1	0.013
CFB	complement factor B	0.013
CD1A	CD1a molecule	0.013
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.013
SASH3	SAM and SH3 domain containing 3	0.013	Mouse
IFNA10	interferon, alpha 10	0.013	Human
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.013
CA12	carbonic anhydrase XII	0.013
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.013
CD1B	CD1b molecule	0.013
CST3	cystatin C	0.013
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.013
GPR171	G protein-coupled receptor 171	0.013
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.013
PDCD1	programmed cell death 1	0.013
RETN	resistin	0.013
CFI	complement factor I	0.013
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.013
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
NCKAP1L	NCK-associated protein 1-like	0.013
CD28	CD28 molecule	0.013	Mouse
TFEC	transcription factor EC	0.013
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.013
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.013
IRAK2	interleukin-1 receptor-associated kinase 2	0.013
LBP	lipopolysaccharide binding protein	0.013
HSPA1L	heat shock 70kDa protein 1-like	0.013
CD1C	CD1c molecule	0.013
NUMBL	numb homolog (Drosophila)-like	0.013
BID	BH3 interacting domain death agonist	0.013
SIGLEC5	sialic acid binding Ig-like lectin 5	0.013
CD44	CD44 molecule (Indian blood group)	0.012
CFP	complement factor properdin	0.012
BARD1	BRCA1 associated RING domain 1	0.012
SLA	Src-like-adaptor	0.012
IFNGR1	interferon gamma receptor 1	0.012
PPAP2B	phosphatidic acid phosphatase type 2B	0.012
S100A12	S100 calcium binding protein A12	0.012
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.012
RUNX2	runt-related transcription factor 2	0.012
RUNX1	runt-related transcription factor 1	0.012
PDCD1LG2	programmed cell death 1 ligand 2	0.012	Human
DNASE1L3	deoxyribonuclease I-like 3	0.012
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.012
ACP5	acid phosphatase 5, tartrate resistant	0.012
TMEM173	transmembrane protein 173	0.012
TYROBP	TYRO protein tyrosine kinase binding protein	0.012
CDCP1	CUB domain containing protein 1	0.012
CCDC85B	coiled-coil domain containing 85B	0.012
ICOS	inducible T-cell co-stimulator	0.012
CXCL3	chemokine (C-X-C motif) ligand 3	0.012
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.012	Mouse
MAPK12	mitogen-activated protein kinase 12	0.012
MED15	mediator complex subunit 15	0.012
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.012
TLR1	toll-like receptor 1	0.012
PRKD2	protein kinase D2	0.012
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.012
ADPRH	ADP-ribosylarginine hydrolase	0.012
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.012	Human
TMSB4X	thymosin beta 4, X-linked	0.012
GPR35	G protein-coupled receptor 35	0.012
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.012
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.012	Mouse
IL6	interleukin 6 (interferon, beta 2)	0.012	Mouse
CD160	CD160 molecule	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012
CD72	CD72 molecule	0.012
GIMAP4	GTPase, IMAP family member 4	0.012
IFI30	interferon, gamma-inducible protein 30	0.012
CD27	CD27 molecule	0.012
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.012
NOD1	nucleotide-binding oligomerization domain containing 1	0.011
CD209	CD209 molecule	0.011
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
INHBA	inhibin, beta A	0.011
RGS16	regulator of G-protein signaling 16	0.011
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.011	Mouse
FPR1	formyl peptide receptor 1	0.011
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.011
NLRP3	NLR family, pyrin domain containing 3	0.011
ATM	ataxia telangiectasia mutated	0.011
BLNK	B-cell linker	0.011
FSTL1	follistatin-like 1	0.011
NCF4	neutrophil cytosolic factor 4, 40kDa	0.011
RFC1	replication factor C (activator 1) 1, 145kDa	0.011
SAA4	serum amyloid A4, constitutive	0.011
LAMP3	lysosomal-associated membrane protein 3	0.011
CXCL16	chemokine (C-X-C motif) ligand 16	0.011
GAA	glucosidase, alpha; acid	0.011
MYD88	myeloid differentiation primary response gene (88)	0.011	Mouse
CD79B	CD79b molecule, immunoglobulin-associated beta	0.011
NLRC5	NLR family, CARD domain containing 5	0.011
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.011
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.011	Human
GPR132	G protein-coupled receptor 132	0.011
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.011	Human
NOS2	nitric oxide synthase 2, inducible	0.011
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.011
NUMB	numb homolog (Drosophila)	0.011
CD14	CD14 molecule	0.011
SAP30BP	SAP30 binding protein	0.011
HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2	0.011
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.011
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.011
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	0.011
AIF1	allograft inflammatory factor 1	0.011
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.011
MYO5A	myosin VA (heavy chain 12, myoxin)	0.011
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.011
G0S2	G0/G1switch 2	0.011
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.011
ZNF512B	zinc finger protein 512B	0.010
CXCL5	chemokine (C-X-C motif) ligand 5	0.010
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.010
INSIG2	insulin induced gene 2	0.010
HLA-DQB2	major histocompatibility complex, class II, DQ beta 2	0.010
IFNA14	interferon, alpha 14	0.010
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.010
RHOA	ras homolog gene family, member A	0.010
TOP1	topoisomerase (DNA) I	0.010
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.010
TMEM176A	transmembrane protein 176A	0.010
IL12RB1	interleukin 12 receptor, beta 1	0.010
XCL2	chemokine (C motif) ligand 2	0.010	Human
ASGR2	asialoglycoprotein receptor 2	0.010
SNX2	sorting nexin 2	0.010
SELL	selectin L	0.010
IL18BP	interleukin 18 binding protein	0.010
CCL24	chemokine (C-C motif) ligand 24	0.010	Human
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.010
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.010	Human
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.010
MYH14	myosin, heavy chain 14, non-muscle	0.010
LAG3	lymphocyte-activation gene 3	0.010
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.010
APOC1	apolipoprotein C-I	0.010
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.010
SLC43A3	solute carrier family 43, member 3	0.010
IFNA16	interferon, alpha 16	0.010	Human
LAIR2	leukocyte-associated immunoglobulin-like receptor 2	0.010	Human