IMP
Process View
isotype switching
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "isotype switching"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Tnf | tumor necrosis factor | 0.981 | Mouse | |
| Foxp3 | forkhead box P3 | 0.975 | ||
| Ifng | interferon gamma | 0.955 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.947 | ||
| Il10 | interleukin 10 | 0.944 | ||
| Cd40 | CD40 antigen | 0.914 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.804 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.726 | Mouse | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.722 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.712 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.689 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.669 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.660 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.633 | Mouse | |
| Lta | lymphotoxin A | 0.632 | Mouse | |
| Ltb | lymphotoxin B | 0.589 | ||
| Igh | immunoglobulin heavy chain complex | 0.552 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.502 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.453 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.426 | ||
| Fyn | Fyn proto-oncogene | 0.400 | ||
| Il4ra | interleukin 4 receptor, alpha | 0.366 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.363 | ||
| Il6 | interleukin 6 | 0.355 | ||
| Pten | phosphatase and tensin homolog | 0.350 | ||
| Pdcd1 | programmed cell death 1 | 0.349 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.340 | ||
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.312 | Mouse | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.299 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.297 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.289 | ||
| Irf9 | interferon regulatory factor 9 | 0.288 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.276 | Mouse | |
| Il6st | interleukin 6 signal transducer | 0.269 | Mouse | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.250 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.234 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.222 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.219 | ||
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.213 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.200 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.200 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.196 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.190 | ||
| Tlr4 | toll-like receptor 4 | 0.180 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.177 | ||
| Lyz2 | lysozyme 2 | 0.175 | ||
| Fgf10 | fibroblast growth factor 10 | 0.164 | ||
| Tbx3 | T-box 3 | 0.150 | Mouse | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.150 | ||
| Brca1 | breast cancer 1 | 0.143 | ||
| Cd19 | CD19 antigen | 0.138 | ||
| Il4 | interleukin 4 | 0.136 | ||
| Gpr132 | G protein-coupled receptor 132 | 0.133 | ||
| Brca2 | breast cancer 2 | 0.115 | ||
| Hoxa1 | homeobox A1 | 0.113 | ||
| Tcra | T-cell receptor alpha chain | 0.112 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.110 | Mouse | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.109 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.109 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.107 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.107 | ||
| Nanog | Nanog homeobox | 0.106 | ||
| Irf4 | interferon regulatory factor 4 | 0.106 | ||
| Wt1 | Wilms tumor 1 homolog | 0.105 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.104 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.104 | ||
| Cd4 | CD4 antigen | 0.103 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.103 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.102 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.099 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.098 | ||
| Cd274 | CD274 antigen | 0.097 | ||
| Cd28 | CD28 antigen | 0.095 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.092 | ||
| Irf1 | interferon regulatory factor 1 | 0.092 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.091 | ||
| Gdf3 | growth differentiation factor 3 | 0.086 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.084 | ||
| Trim21 | tripartite motif-containing 21 | 0.084 | ||
| Cd160 | CD160 antigen | 0.084 | ||
| Icos | inducible T-cell co-stimulator | 0.084 | Mouse | |
| Itgal | integrin alpha L | 0.080 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.078 | ||
| Tbx5 | T-box 5 | 0.076 | Mouse | |
| Lepr | leptin receptor | 0.073 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.071 | ||
| Foxf1a | forkhead box F1a | 0.067 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.067 | ||
| Trp53 | transformation related protein 53 | 0.066 | ||
| Il12rb1 | interleukin 12 receptor, beta 1 | 0.065 | ||
| Gja5 | gap junction protein, alpha 5 | 0.065 | ||
| Zbp1 | Z-DNA binding protein 1 | 0.064 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.064 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.063 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.063 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.061 | ||
| Tnfsf8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.060 | ||
| Pou3f4 | POU domain, class 3, transcription factor 4 | 0.059 | ||
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.059 | ||
| Jak2 | Janus kinase 2 | 0.058 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.058 | ||
| Lif | leukemia inhibitory factor | 0.058 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.057 | ||
| Pdcd1lg2 | programmed cell death 1 ligand 2 | 0.057 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.056 | ||
| Tox | thymocyte selection-associated high mobility group box | 0.056 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.055 | ||
| Runx1 | runt related transcription factor 1 | 0.055 | ||
| Pax2 | paired box gene 2 | 0.054 | ||
| Itk | IL2-inducible T-cell kinase | 0.054 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.053 | ||
| Il2 | interleukin 2 | 0.052 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.052 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.052 | ||
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.048 | ||
| Mcm8 | minichromosome maintenance deficient 8 (S. cerevisiae) | 0.048 | ||
| Cd247 | CD247 antigen | 0.047 | ||
| Sh2d2a | SH2 domain protein 2A | 0.047 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.047 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.047 | ||
| Tbx4 | T-box 4 | 0.047 | Mouse | |
| Trp53bp1 | transformation related protein 53 binding protein 1 | 0.046 | ||
| Pgrmc1 | progesterone receptor membrane component 1 | 0.045 | ||
| Il1b | interleukin 1 beta | 0.044 | ||
| Cd6 | CD6 antigen | 0.044 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.044 | ||
| Il21r | interleukin 21 receptor | 0.043 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.042 | Mouse | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.042 | ||
| Runx3 | runt related transcription factor 3 | 0.042 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.041 | ||
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.041 | ||
| Nog | noggin | 0.039 | ||
| Spp1 | secreted phosphoprotein 1 | 0.039 | ||
| Jak1 | Janus kinase 1 | 0.039 | ||
| Gzmk | granzyme K | 0.039 | ||
| Noto | notochord homolog (Xenopus laevis) | 0.039 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.038 | ||
| Cd5 | CD5 antigen | 0.036 | ||
| Tbx21 | T-box 21 | 0.036 | ||
| Nbn | nibrin | 0.036 | ||
| Folr4 | folate receptor 4 (delta) | 0.036 | ||
| Sgol1 | shugoshin-like 1 (S. pombe) | 0.036 | ||
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.036 | ||
| Cd22 | CD22 antigen | 0.034 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.034 | ||
| Mx2 | myxovirus (influenza virus) resistance 2 | 0.034 | ||
| Apc | adenomatosis polyposis coli | 0.034 | ||
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.033 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.033 | ||
| Il7 | interleukin 7 | 0.033 | ||
| Casp1 | caspase 1 | 0.033 | ||
| Gm12185 | predicted gene 12185 | 0.033 | ||
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.032 | ||
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.032 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.032 | ||
| Cd44 | CD44 antigen | 0.032 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.032 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.032 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.031 | ||
| Adcy4 | adenylate cyclase 4 | 0.031 | ||
| Mdc1 | mediator of DNA damage checkpoint 1 | 0.030 | Mouse | |
| Foxg1 | forkhead box G1 | 0.030 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.030 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.030 | ||
| Gimap7 | GTPase, IMAP family member 7 | 0.030 | ||
| Msx1 | homeobox, msh-like 1 | 0.030 | ||
| Tlr2 | toll-like receptor 2 | 0.030 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.029 | ||
| Spna1 | spectrin alpha 1 | 0.029 | ||
| Rybp | RING1 and YY1 binding protein | 0.029 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.028 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.028 | ||
| Phf19 | PHD finger protein 19 | 0.028 | ||
| Gcm2 | glial cells missing homolog 2 (Drosophila) | 0.028 | ||
| Il12rb2 | interleukin 12 receptor, beta 2 | 0.028 | Mouse | |
| Dmtf1 | cyclin D binding myb-like transcription factor 1 | 0.027 | ||
| Tnfsf4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.027 | ||
| Pag1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.027 | ||
| Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.027 | ||
| Ctsw | cathepsin W | 0.027 | ||
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.026 | ||
| Sp110 | Sp110 nuclear body protein | 0.026 | ||
| Prrx1 | paired related homeobox 1 | 0.026 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.026 | ||
| Trem1 | triggering receptor expressed on myeloid cells 1 | 0.026 | ||
| Gbp7 | guanylate binding protein 7 | 0.026 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.026 | ||
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.026 | ||
| Ciita | class II transactivator | 0.026 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.026 | ||
| Gata3 | GATA binding protein 3 | 0.026 | ||
| Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.026 | ||
| Rnf2 | ring finger protein 2 | 0.026 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.026 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.025 | ||
| Cd47 | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 0.025 | ||
| Sh2d1a | SH2 domain protein 1A | 0.025 | ||
| She | src homology 2 domain-containing transforming protein E | 0.025 | ||
| Rhoh | ras homolog gene family, member H | 0.025 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.025 | ||
| Ccl17 | chemokine (C-C motif) ligand 17 | 0.025 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.025 | ||
| Hira | histone cell cycle regulation defective homolog A (S. cerevisiae) | 0.025 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.024 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.024 | Mouse | |
| 4933424B01Rik | RIKEN cDNA 4933424B01 gene | 0.024 | ||
| Mefv | Mediterranean fever | 0.024 | ||
| Gzmb | granzyme B | 0.024 | ||
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.024 | ||
| Cd96 | CD96 antigen | 0.024 | ||
| Msc | musculin | 0.024 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.024 | ||
| Ccrl2 | chemokine (C-C motif) receptor-like 2 | 0.024 | ||
| Hmx3 | H6 homeobox 3 | 0.024 | ||
| Col13a1 | collagen, type XIII, alpha 1 | 0.023 | ||
| Xrcc5 | X-ray repair complementing defective repair in Chinese hamster cells 5 | 0.023 | ||
| Aoah | acyloxyacyl hydrolase | 0.023 | ||
| Rem1 | rad and gem related GTP binding protein 1 | 0.023 | ||
| Hsp90b1 | heat shock protein 90, beta (Grp94), member 1 | 0.023 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.023 | ||
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.023 | ||
| Irgm2 | immunity-related GTPase family M member 2 | 0.023 | ||
| Oas3 | 2'-5' oligoadenylate synthetase 3 | 0.023 | ||
| Fgd3 | FYVE, RhoGEF and PH domain containing 3 | 0.023 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.023 | ||
| Atr | ataxia telangiectasia and Rad3 related | 0.023 | ||
| Dbr1 | debranching enzyme homolog 1 (S. cerevisiae) | 0.023 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.023 | ||
| Hrh2 | histamine receptor H2 | 0.023 | ||
| Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) | 0.022 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.022 | ||
| Rasal3 | RAS protein activator like 3 | 0.022 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.022 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.022 | ||
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.021 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.021 | ||
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.021 | ||
| Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.021 | ||
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.021 | ||
| Cd8a | CD8 antigen, alpha chain | 0.021 | ||
| Notch4 | Notch gene homolog 4 (Drosophila) | 0.021 | ||
| Elf4 | E74-like factor 4 (ets domain transcription factor) | 0.020 | ||
| Il13ra2 | interleukin 13 receptor, alpha 2 | 0.020 | ||
| Prkcd | protein kinase C, delta | 0.020 | ||
| Rad50 | RAD50 homolog (S. cerevisiae) | 0.020 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.020 | ||
| Madcam1 | mucosal vascular addressin cell adhesion molecule 1 | 0.020 | ||
| Kit | kit oncogene | 0.020 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.020 | ||
| Apoe | apolipoprotein E | 0.020 | ||
| Wnt9b | wingless-type MMTV integration site 9B | 0.020 | ||
| Rfc1 | replication factor C (activator 1) 1 | 0.020 | ||
| Ncapd3 | non-SMC condensin II complex, subunit D3 | 0.020 | ||
| Nod2 | nucleotide-binding oligomerization domain containing 2 | 0.019 | ||
| Wnt10b | wingless related MMTV integration site 10b | 0.019 | ||
| Stk11 | serine/threonine kinase 11 | 0.019 | ||
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.019 | ||
| Ikzf3 | IKAROS family zinc finger 3 | 0.019 | ||
| Gbp1 | guanylate binding protein 1 | 0.019 | ||
| Osr1 | odd-skipped related 1 (Drosophila) | 0.019 | ||
| Gp1ba | glycoprotein 1b, alpha polypeptide | 0.019 | ||
| Tcf3 | transcription factor 3 | 0.019 | ||
| Itgav | integrin alpha V | 0.019 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.019 | ||
| Tnni2 | troponin I, skeletal, fast 2 | 0.019 | ||
| Fndc7 | fibronectin type III domain containing 7 | 0.019 | ||
| Tnfrsf18 | tumor necrosis factor receptor superfamily, member 18 | 0.019 | ||
| Fgf3 | fibroblast growth factor 3 | 0.019 | ||
| Blk | B lymphoid kinase | 0.019 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.019 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.019 | ||
| Pax9 | paired box gene 9 | 0.018 | ||
| Hhex | hematopoietically expressed homeobox | 0.018 | ||
| Cd40lg | CD40 ligand | 0.018 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.018 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.018 | ||
| Casp12 | caspase 12 | 0.018 | ||
| Il22 | interleukin 22 | 0.018 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.018 | ||
| Sall1 | sal-like 1 (Drosophila) | 0.018 | ||
| Igtp | interferon gamma induced GTPase | 0.018 | ||
| Usp18 | ubiquitin specific peptidase 18 | 0.018 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.018 | ||
| Rb1 | retinoblastoma 1 | 0.018 | ||
| Ahr | aryl-hydrocarbon receptor | 0.018 | ||
| Larp7 | La ribonucleoprotein domain family, member 7 | 0.018 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.017 | ||
| Cmklr1 | chemokine-like receptor 1 | 0.017 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.017 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.017 | ||
| Nodal | nodal | 0.017 | ||
| Tnfsf13b | tumor necrosis factor (ligand) superfamily, member 13b | 0.017 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.017 | ||
| Gata4 | GATA binding protein 4 | 0.017 | ||
| Cbl | Casitas B-lineage lymphoma | 0.017 | ||
| Tbx20 | T-box 20 | 0.017 | Mouse | |
| Lig4 | ligase IV, DNA, ATP-dependent | 0.017 | ||
| Tcf15 | transcription factor 15 | 0.017 | ||
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.017 | ||
| Gak | cyclin G associated kinase | 0.017 | ||
| Skp2 | S-phase kinase-associated protein 2 (p45) | 0.017 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.016 | ||
| Rel | reticuloendotheliosis oncogene | 0.016 | ||
| Xirp1 | xin actin-binding repeat containing 1 | 0.016 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.016 | ||
| C3 | complement component 3 | 0.016 | ||
| Alx1 | ALX homeobox 1 | 0.016 | ||
| Zc3h12a | zinc finger CCCH type containing 12A | 0.016 | ||
| Rag2 | recombination activating gene 2 | 0.016 | ||
| Sox7 | SRY-box containing gene 7 | 0.016 | ||
| Nppb | natriuretic peptide type B | 0.016 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.016 | ||
| Lat | linker for activation of T cells | 0.016 | ||
| Arid5a | AT rich interactive domain 5A (MRF1-like) | 0.016 | ||
| Gm13290 | predicted gene 13290 | 0.016 | ||
| Nfil3 | nuclear factor, interleukin 3, regulated | 0.016 | ||
| Asb10 | ankyrin repeat and SOCS box-containing 10 | 0.016 | ||
| Exosc7 | exosome component 7 | 0.016 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.016 | ||
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.016 | ||
| Kitl | kit ligand | 0.016 | ||
| Mta1 | metastasis associated 1 | 0.016 | ||
| Ar | androgen receptor | 0.016 | ||
| Il2ra | interleukin 2 receptor, alpha chain | 0.016 | ||
| Sykb | spleen tyrosine kinase | 0.016 | ||
| Chl1 | cell adhesion molecule with homology to L1CAM | 0.016 | ||
| Irf8 | interferon regulatory factor 8 | 0.015 | ||
| Traf1 | TNF receptor-associated factor 1 | 0.015 | ||
| Cox4i2 | cytochrome c oxidase subunit IV isoform 2 | 0.015 | ||
| Cxcl5 | chemokine (C-X-C motif) ligand 5 | 0.015 | ||
| Rttn | rotatin | 0.015 | ||
| Rasip1 | Ras interacting protein 1 | 0.015 | ||
| Mis12 | MIS12 homolog (yeast) | 0.015 | ||
| Rfwd3 | ring finger and WD repeat domain 3 | 0.015 | ||
| Itfg1 | integrin alpha FG-GAP repeat containing 1 | 0.015 | ||
| Grap2 | GRB2-related adaptor protein 2 | 0.015 | ||
| Pla2r1 | phospholipase A2 receptor 1 | 0.015 | ||
| Bdnf | brain derived neurotrophic factor | 0.015 | ||
| Selp | selectin, platelet | 0.015 | ||
| Pcdh12 | protocadherin 12 | 0.015 | ||
| Zbtb46 | zinc finger and BTB domain containing 46 | 0.015 | ||
| 2210018M11Rik | RIKEN cDNA 2210018M11 gene | 0.015 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.015 | ||
| Tg | thyroglobulin | 0.015 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.015 | ||
| Ifnar2 | interferon (alpha and beta) receptor 2 | 0.015 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.015 | ||
| Prap1 | proline-rich acidic protein 1 | 0.015 | ||
| Rnf168 | ring finger protein 168 | 0.015 | ||
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.015 | ||
| Bdkrb2 | bradykinin receptor, beta 2 | 0.015 | ||
| Cdx2 | caudal type homeobox 2 | 0.015 | ||
| Piwil1 | piwi-like homolog 1 (Drosophila) | 0.015 | ||
| Zmym1 | zinc finger, MYM domain containing 1 | 0.015 | ||
| Stx11 | syntaxin 11 | 0.015 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.015 | ||
| Dusp2 | dual specificity phosphatase 2 | 0.015 | ||
| Aldh1a3 | aldehyde dehydrogenase family 1, subfamily A3 | 0.015 | ||
| Il25 | interleukin 25 | 0.015 | ||
| Ccl22 | chemokine (C-C motif) ligand 22 | 0.014 | ||
| Hmga2 | high mobility group AT-hook 2 | 0.014 | ||
| Gimap1 | GTPase, IMAP family member 1 | 0.014 | ||
| Agap2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 0.014 | ||
| Sept1 | septin 1 | 0.014 | ||
| Ikzf2 | IKAROS family zinc finger 2 | 0.014 | ||
| Foxn1 | forkhead box N1 | 0.014 | ||
| Asprv1 | aspartic peptidase, retroviral-like 1 | 0.014 | ||
| Kdr | kinase insert domain protein receptor | 0.014 | ||
| Art2a-ps | ADP-ribosyltransferase 2a, pseudogene | 0.014 | ||
| Cd7 | CD7 antigen | 0.014 | ||
| Cxcr6 | chemokine (C-X-C motif) receptor 6 | 0.014 | ||
| Htt | huntingtin | 0.014 | ||
| Ggta1 | glycoprotein galactosyltransferase alpha 1, 3 | 0.014 | ||
| Nup85 | nucleoporin 85 | 0.014 | ||
| Iigp1 | interferon inducible GTPase 1 | 0.014 | ||
| Nfatc4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.014 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.014 | ||
| Gpr114 | G protein-coupled receptor 114 | 0.014 | ||
| Dut | deoxyuridine triphosphatase | 0.014 | ||
| Nacc1 | nucleus accumbens associated 1, BEN and BTB (POZ) domain containing | 0.014 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.014 | ||
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.014 | Mouse | |
| Cd8b1 | CD8 antigen, beta chain 1 | 0.014 | ||
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.014 | ||
| Mmp10 | matrix metallopeptidase 10 | 0.014 | ||
| Slamf6 | SLAM family member 6 | 0.014 | ||
| Hes7 | hairy and enhancer of split 7 (Drosophila) | 0.014 | ||
| Mecom | MDS1 and EVI1 complex locus | 0.014 | ||
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.014 | Mouse | |
| Crb2 | crumbs homolog 2 (Drosophila) | 0.014 | ||
| Cr2 | complement receptor 2 | 0.014 | ||
| Mphosph9 | M-phase phosphoprotein 9 | 0.014 | ||
| Orc5 | origin recognition complex, subunit 5 | 0.014 | ||
| Itga6 | integrin alpha 6 | 0.014 | ||
| Art5 | ADP-ribosyltransferase 5 | 0.014 | ||
| Nppa | natriuretic peptide type A | 0.013 | ||
| Gata2 | GATA binding protein 2 | 0.013 | ||
| Mtrf1l | mitochondrial translational release factor 1-like | 0.013 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.013 | Mouse | |
| Onecut3 | one cut domain, family member 3 | 0.013 | ||
| Runx2 | runt related transcription factor 2 | 0.013 | ||
| Creb1 | cAMP responsive element binding protein 1 | 0.013 | ||
| Pold1 | polymerase (DNA directed), delta 1, catalytic subunit | 0.013 | ||
| Ttc7 | tetratricopeptide repeat domain 7 | 0.013 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.013 | ||
| Dusp9 | dual specificity phosphatase 9 | 0.013 | ||
| Rbm14 | RNA binding motif protein 14 | 0.013 | ||
| Ubd | ubiquitin D | 0.013 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.013 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.013 | ||
| C130039O16Rik | RIKEN cDNA C130039O16 gene | 0.013 | ||
| Cyp26c1 | cytochrome P450, family 26, subfamily c, polypeptide 1 | 0.013 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.013 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.013 | ||
| Has2 | hyaluronan synthase 2 | 0.013 | ||
| Tcf21 | transcription factor 21 | 0.013 | ||
| Phospho1 | phosphatase, orphan 1 | 0.013 | ||
| Pax5 | paired box gene 5 | 0.013 | ||
| Wwox | WW domain-containing oxidoreductase | 0.013 | ||
| Siglece | sialic acid binding Ig-like lectin E | 0.013 | ||
| Adar | adenosine deaminase, RNA-specific | 0.013 | ||
| Prpf3 | PRP3 pre-mRNA processing factor 3 homolog (yeast) | 0.013 | ||
| Inhba | inhibin beta-A | 0.013 | ||
| Bpil1 | bactericidal/permeability-increasing protein-like 1 | 0.013 | ||
| Ikbkg | inhibitor of kappaB kinase gamma | 0.013 | ||
| Rfwd2 | ring finger and WD repeat domain 2 | 0.013 | ||
| Ccnb1ip1 | cyclin B1 interacting protein 1 | 0.013 | ||
| Tcf7 | transcription factor 7, T-cell specific | 0.013 | ||
| Oscar | osteoclast associated receptor | 0.013 | ||
| Cd3d | CD3 antigen, delta polypeptide | 0.013 | ||
| Casp8 | caspase 8 | 0.013 | ||
| Dnmt3l | DNA (cytosine-5-)-methyltransferase 3-like | 0.013 | ||
| Safb | scaffold attachment factor B | 0.013 | ||
| Cd1d2 | CD1d2 antigen | 0.013 | ||
| Vgll1 | vestigial like 1 homolog (Drosophila) | 0.013 | ||
| Paxip1 | PAX interacting (with transcription-activation domain) protein 1 | 0.013 | ||
| Alx4 | aristaless-like homeobox 4 | 0.013 | ||
| Itgb3 | integrin beta 3 | 0.013 | ||
| Ptgir | prostaglandin I receptor (IP) | 0.013 | ||
| Hoxd1 | homeobox D1 | 0.012 | ||
| Spn | sialophorin | 0.012 | ||
| Tapbp | TAP binding protein | 0.012 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.012 | Mouse | |
| Ifi203 | interferon activated gene 203 | 0.012 | ||
| Tlx1 | T-cell leukemia, homeobox 1 | 0.012 | ||
| Itgb7 | integrin beta 7 | 0.012 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.012 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.012 | ||
| Tor3a | torsin family 3, member A | 0.012 | ||
| Cd80 | CD80 antigen | 0.012 | ||
| Meox1 | mesenchyme homeobox 1 | 0.012 | ||
| Sfpi1 | SFFV proviral integration 1 | 0.012 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.012 | ||
| Hoxb4 | homeobox B4 | 0.012 | ||
| Bach2 | BTB and CNC homology 2 | 0.012 | ||
| Il18r1 | interleukin 18 receptor 1 | 0.012 | ||
| Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.012 | ||
| Tada2a | transcriptional adaptor 2A | 0.012 | ||
| Wdr75 | WD repeat domain 75 | 0.012 | ||
| Sp100 | nuclear antigen Sp100 | 0.012 | ||
| Slc12a8 | solute carrier family 12 (potassium/chloride transporters), member 8 | 0.012 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.012 | ||
| Chd1l | chromodomain helicase DNA binding protein 1-like | 0.012 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.012 | ||
| Lamp3 | lysosomal-associated membrane protein 3 | 0.012 | ||
| Dkk2 | dickkopf homolog 2 (Xenopus laevis) | 0.012 | ||
| Ep400 | E1A binding protein p400 | 0.012 | ||
| Irg1 | immunoresponsive gene 1 | 0.012 | ||
| Cxadr | coxsackie virus and adenovirus receptor | 0.012 | ||
| Tmco4 | transmembrane and coiled-coil domains 4 | 0.012 | ||
| Braf | Braf transforming gene | 0.012 | ||
| Cd27 | CD27 antigen | 0.012 | ||
| Ankrd26 | ankyrin repeat domain 26 | 0.012 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.012 | ||
| Gzmc | granzyme C | 0.012 | ||
| Zfp36 | zinc finger protein 36 | 0.012 | ||
| Supt16h | suppressor of Ty 16 homolog (S. cerevisiae) | 0.012 | ||
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.012 | ||
| Parp12 | poly (ADP-ribose) polymerase family, member 12 | 0.012 | ||
| Ctsk | cathepsin K | 0.012 | ||
| Ncapd2 | non-SMC condensin I complex, subunit D2 | 0.012 | ||
| Pikfyve | phosphoinositide kinase, FYVE finger containing | 0.012 | ||
| Gbp2 | guanylate binding protein 2 | 0.012 | ||
| Slfn1 | schlafen 1 | 0.012 | ||
| Vav1 | vav 1 oncogene | 0.012 | ||
| Fbxo47 | F-box protein 47 | 0.012 | ||
| Edil3 | EGF-like repeats and discoidin I-like domains 3 | 0.012 | ||
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.012 | ||
| Rab37 | RAB37, member of RAS oncogene family | 0.012 | ||
| Ppat | phosphoribosyl pyrophosphate amidotransferase | 0.012 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.012 | ||
| Cabp2 | calcium binding protein 2 | 0.011 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.011 | ||
| Nup35 | nucleoporin 35 | 0.011 | ||
| Stc2 | stanniocalcin 2 | 0.011 | ||
| Cd180 | CD180 antigen | 0.011 | ||
| BC020535 | cDNA sequence BC020535 | 0.011 | ||
| Adamts7 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 | 0.011 | ||
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.011 | ||
| Meox2 | mesenchyme homeobox 2 | 0.011 | ||
| Tnfrsf25 | tumor necrosis factor receptor superfamily, member 25 | 0.011 | ||
| Rif1 | Rap1 interacting factor 1 homolog (yeast) | 0.011 | ||
| Tgtp2 | T-cell specific GTPase 2 | 0.011 | ||
| Cxcl11 | chemokine (C-X-C motif) ligand 11 | 0.011 | ||
| Mmp3 | matrix metallopeptidase 3 | 0.011 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.011 | ||
| Terf1 | telomeric repeat binding factor 1 | 0.011 | ||
| Sf1 | splicing factor 1 | 0.011 | ||
| Xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.011 | ||
| Ccl1 | chemokine (C-C motif) ligand 1 | 0.011 | ||
| Fut7 | fucosyltransferase 7 | 0.011 | ||
| Exosc8 | exosome component 8 | 0.011 | ||
| Rrad | Ras-related associated with diabetes | 0.011 | ||
| Htra3 | HtrA serine peptidase 3 | 0.011 | ||
| Il12a | interleukin 12a | 0.011 | ||
| Tgif2 | TGFB-induced factor homeobox 2 | 0.011 | ||
| Atad5 | ATPase family, AAA domain containing 5 | 0.011 | ||
| H2-T24 | histocompatibility 2, T region locus 24 | 0.011 | ||
| Etv6 | ets variant gene 6 (TEL oncogene) | 0.011 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.011 | ||
| Gatad2b | GATA zinc finger domain containing 2B | 0.011 | ||
| Il11 | interleukin 11 | 0.011 | ||
| Il12b | interleukin 12b | 0.011 | ||
| Timeless | timeless homolog (Drosophila) | 0.011 | ||
| Nfatc1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 0.011 | ||
| Gbp3 | guanylate binding protein 3 | 0.011 | ||
| Gata6 | GATA binding protein 6 | 0.011 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.011 | ||
| Il13ra1 | interleukin 13 receptor, alpha 1 | 0.011 | ||
| Ly6i | lymphocyte antigen 6 complex, locus I | 0.011 | ||
| Itgb6 | integrin beta 6 | 0.011 | ||
| Kdm1a | lysine (K)-specific demethylase 1A | 0.011 | ||
| Ly9 | lymphocyte antigen 9 | 0.011 | ||
| Lgals8 | lectin, galactose binding, soluble 8 | 0.011 | ||
| Gimap3 | GTPase, IMAP family member 3 | 0.011 | ||
| Slc10a6 | solute carrier family 10 (sodium/bile acid cotransporter family), member 6 | 0.011 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.011 | ||
| Wisp1 | WNT1 inducible signaling pathway protein 1 | 0.011 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.011 | ||
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.011 | ||
| Itga7 | integrin alpha 7 | 0.011 | ||
| Wrn | Werner syndrome homolog (human) | 0.011 | ||
| Stat4 | signal transducer and activator of transcription 4 | 0.011 | Mouse | |
| Nek6 | NIMA (never in mitosis gene a)-related expressed kinase 6 | 0.011 | ||
| S1pr1 | sphingosine-1-phosphate receptor 1 | 0.011 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.011 | ||
| Txk | TXK tyrosine kinase | 0.011 | ||
| Dkc1 | dyskeratosis congenita 1, dyskerin homolog (human) | 0.011 | ||
| Yes1 | Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 | 0.011 | ||
| LOC677008 | natural killer cell receptor 2B4-like | 0.011 | ||
| Pdcd7 | programmed cell death 7 | 0.011 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.011 | ||
| Wnt2b | wingless related MMTV integration site 2b | 0.011 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.011 | ||
| Zbtb33 | zinc finger and BTB domain containing 33 | 0.011 | ||
| Sell | selectin, lymphocyte | 0.010 | ||
| Cst7 | cystatin F (leukocystatin) | 0.010 | ||
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.010 | ||
| Aff1 | AF4/FMR2 family, member 1 | 0.010 | ||
| Insm2 | insulinoma-associated 2 | 0.010 | ||
| Msgn1 | mesogenin 1 | 0.010 | ||
| Cdca7l | cell division cycle associated 7 like | 0.010 | ||
| Foxc1 | forkhead box C1 | 0.010 | ||
| B2m | beta-2 microglobulin | 0.010 | ||
| Fgf18 | fibroblast growth factor 18 | 0.010 | ||
| Clspn | claspin homolog (Xenopus laevis) | 0.010 | ||
| Flt3l | FMS-like tyrosine kinase 3 ligand | 0.010 | ||
| Col11a2 | collagen, type XI, alpha 2 | 0.010 | ||
| Dppa3 | developmental pluripotency-associated 3 | 0.010 | ||
| Phc1 | polyhomeotic-like 1 (Drosophila) | 0.010 | ||
| Thsd1 | thrombospondin, type I, domain 1 | 0.010 | ||
| Irx4 | Iroquois related homeobox 4 (Drosophila) | 0.010 | ||
| Bglap | bone gamma carboxyglutamate protein | 0.010 | ||
| Rora | RAR-related orphan receptor alpha | 0.010 | ||
| Ccl20 | chemokine (C-C motif) ligand 20 | 0.010 | ||
| Itch | itchy, E3 ubiquitin protein ligase | 0.010 | ||
| Csnk2a1 | casein kinase 2, alpha 1 polypeptide | 0.010 | ||
| Eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 0.010 | ||
| Hdac7 | histone deacetylase 7 | 0.010 | ||
| Foxo3 | forkhead box O3 | 0.010 | ||
| Elk3 | ELK3, member of ETS oncogene family | 0.010 | ||
| Cdan1 | congenital dyserythropoietic anemia, type I (human) | 0.010 | ||
| Fcer2a | Fc receptor, IgE, low affinity II, alpha polypeptide | 0.010 | ||
| Hlx | H2.0-like homeobox | 0.010 | ||
| Rasgrp4 | RAS guanyl releasing protein 4 | 0.010 | ||
| Slfn3 | schlafen 3 | 0.010 | ||
| Lgals9 | lectin, galactose binding, soluble 9 | 0.010 | ||
| Myoz1 | myozenin 1 | 0.010 | ||
| Zbtb2 | zinc finger and BTB domain containing 2 | 0.010 | ||
| Cep78 | centrosomal protein 78 | 0.010 | ||
| Padi4 | peptidyl arginine deiminase, type IV | 0.010 | ||
| Lat2 | linker for activation of T cells family, member 2 | 0.010 | ||
| Camp | cathelicidin antimicrobial peptide | 0.010 | ||
| Bcor | BCL6 interacting corepressor | 0.010 | ||
| Sftpa1 | surfactant associated protein A1 | 0.010 | ||
| Ifna11 | interferon alpha 11 | 0.010 | ||
| Fign | fidgetin | 0.010 | ||
| Gbgt1 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 | 0.010 | ||
| Whrn | whirlin | 0.010 | ||
| Fhl3 | four and a half LIM domains 3 | 0.010 | ||
| Myh7 | myosin, heavy polypeptide 7, cardiac muscle, beta | 0.010 | ||
| Cacna1f | calcium channel, voltage-dependent, alpha 1F subunit | 0.010 | ||
| Dhfr | dihydrofolate reductase | 0.010 |