IMP
Process View
transmembrane receptor protein tyrosine kinase signaling pathway
A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "transmembrane receptor protein tyrosine kinase signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EGFR | epidermal growth factor receptor | 1.000 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 1.000 | ||
| GRB2 | growth factor receptor-bound protein 2 | 1.000 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 1.000 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 1.000 | Human Fly | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 1.000 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 1.000 | Mouse Rat Fly | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 1.000 | Human Rat | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1.000 | Rat | |
| PLCG1 | phospholipase C, gamma 1 | 1.000 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 1.000 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 1.000 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 1.000 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 1.000 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 1.000 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 1.000 | Human | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 1.000 | Mouse | |
| CREBBP | CREB binding protein | 0.999 | ||
| INSR | insulin receptor | 0.999 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.999 | ||
| IRS1 | insulin receptor substrate 1 | 0.999 | ||
| ESR1 | estrogen receptor 1 | 0.999 | Rat | |
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.999 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.998 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.998 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.997 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.997 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.997 | ||
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.997 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.997 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.996 | ||
| GHR | growth hormone receptor | 0.996 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.995 | Mouse | |
| FGFR2 | fibroblast growth factor receptor 2 | 0.995 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.995 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.994 | Human | |
| GAB1 | GRB2-associated binding protein 1 | 0.992 | Human Mouse | |
| LAT | linker for activation of T cells | 0.991 | ||
| DNM2 | dynamin 2 | 0.990 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.986 | Mouse | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.986 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.984 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.984 | Human | |
| JAK2 | Janus kinase 2 | 0.978 | ||
| ATF2 | activating transcription factor 2 | 0.978 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.976 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.973 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.968 | Fly | |
| NCK1 | NCK adaptor protein 1 | 0.966 | Fly | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.965 | Mouse Rat | |
| DUSP1 | dual specificity phosphatase 1 | 0.962 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.962 | Mouse Fly | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.957 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.956 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.953 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.946 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.946 | ||
| EPHA2 | EPH receptor A2 | 0.945 | ||
| JUN | jun proto-oncogene | 0.945 | ||
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.941 | ||
| APP | amyloid beta (A4) precursor protein | 0.940 | Mouse | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.937 | ||
| FHL2 | four and a half LIM domains 2 | 0.935 | ||
| SH3BP4 | SH3-domain binding protein 4 | 0.931 | ||
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.930 | ||
| TEK | TEK tyrosine kinase, endothelial | 0.924 | ||
| IRS2 | insulin receptor substrate 2 | 0.915 | Human Mouse Fly | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.913 | Human Mouse | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.912 | Fly | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.912 | Human | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.909 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.905 | Mouse | |
| NCK2 | NCK adaptor protein 2 | 0.903 | Fly | |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.901 | Human | |
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.897 | Fly | |
| AR | androgen receptor | 0.890 | Mouse | |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.885 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.883 | ||
| VEGFA | vascular endothelial growth factor A | 0.883 | ||
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.880 | ||
| MUC1 | mucin 1, cell surface associated | 0.879 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.878 | Human | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.877 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.858 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.856 | Human Mouse | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.853 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.853 | ||
| MAPK3 | mitogen-activated protein kinase 3 | 0.832 | Human Fly | |
| PDCD6IP | programmed cell death 6 interacting protein | 0.831 | ||
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.829 | Mouse Fly | |
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.827 | ||
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.823 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.816 | Human | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.811 | ||
| THBS1 | thrombospondin 1 | 0.801 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.800 | ||
| PRKCA | protein kinase C, alpha | 0.787 | Mouse | |
| STAMBP | STAM binding protein | 0.774 | ||
| DNM1 | dynamin 1 | 0.773 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.770 | Fly | |
| ATN1 | atrophin 1 | 0.769 | ||
| CRYAB | crystallin, alpha B | 0.766 | ||
| SMAD3 | SMAD family member 3 | 0.760 | ||
| IL4R | interleukin 4 receptor | 0.760 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.753 | Human Fly | |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.749 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.743 | Human | |
| FYB | FYN binding protein | 0.738 | ||
| EPOR | erythropoietin receptor | 0.737 | ||
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.734 | ||
| FBLN1 | fibulin 1 | 0.728 | Human | |
| SYK | spleen tyrosine kinase | 0.722 | ||
| JUP | junction plakoglobin | 0.722 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.710 | Human | |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.710 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.702 | ||
| GH1 | growth hormone 1 | 0.698 | ||
| TSC2 | tuberous sclerosis 2 | 0.697 | Mouse Fly | |
| STAT5A | signal transducer and activator of transcription 5A | 0.696 | Human Mouse | |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.696 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.694 | ||
| YAP1 | Yes-associated protein 1 | 0.690 | ||
| FHL1 | four and a half LIM domains 1 | 0.690 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.687 | ||
| STAT5B | signal transducer and activator of transcription 5B | 0.676 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.671 | ||
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.666 | Fly | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.664 | ||
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.663 | ||
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.662 | ||
| IER3 | immediate early response 3 | 0.660 | ||
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.658 | Human Fly | |
| HDAC6 | histone deacetylase 6 | 0.650 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.649 | ||
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.649 | ||
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.645 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.643 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.636 | ||
| AXL | AXL receptor tyrosine kinase | 0.635 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.635 | ||
| HSPG2 | heparan sulfate proteoglycan 2 | 0.628 | Worm | |
| FN1 | fibronectin 1 | 0.627 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.625 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.617 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.613 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.610 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.603 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.598 | ||
| DUSP6 | dual specificity phosphatase 6 | 0.596 | Zebrafish | |
| CUL1 | cullin 1 | 0.587 | Fly | |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.585 | ||
| SMAD2 | SMAD family member 2 | 0.584 | ||
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.583 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.569 | Fly | |
| PXN | paxillin | 0.563 | ||
| TMEM173 | transmembrane protein 173 | 0.555 | ||
| GDA | guanine deaminase | 0.548 | ||
| TRIP6 | thyroid hormone receptor interactor 6 | 0.548 | ||
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.545 | ||
| UBE3A | ubiquitin protein ligase E3A | 0.542 | ||
| FGA | fibrinogen alpha chain | 0.541 | ||
| PSEN1 | presenilin 1 | 0.541 | Mouse | |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.540 | Human | |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.539 | ||
| DOK4 | docking protein 4 | 0.532 | Mouse | |
| CHRD | chordin | 0.531 | Fly | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.523 | ||
| KRT8 | keratin 8 | 0.513 | ||
| DUSP7 | dual specificity phosphatase 7 | 0.509 | ||
| ILK | integrin-linked kinase | 0.505 | ||
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.500 | ||
| SH2D3A | SH2 domain containing 3A | 0.497 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.497 | Fly | |
| TGFB3 | transforming growth factor, beta 3 | 0.494 | ||
| TGFA | transforming growth factor, alpha | 0.492 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.489 | Human | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.489 | Human | |
| SMAD1 | SMAD family member 1 | 0.485 | ||
| PTK6 | PTK6 protein tyrosine kinase 6 | 0.485 | ||
| RNF11 | ring finger protein 11 | 0.484 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.481 | ||
| RET | ret proto-oncogene | 0.479 | Mouse | |
| IL1R1 | interleukin 1 receptor, type I | 0.479 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.478 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.477 | ||
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.477 | Mouse | |
| NRP1 | neuropilin 1 | 0.477 | ||
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.471 | Mouse | |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.471 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.471 | ||
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.468 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.466 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.452 | ||
| AHNAK | AHNAK nucleoprotein | 0.452 | ||
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.451 | ||
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.450 | Fly | |
| COL6A2 | collagen, type VI, alpha 2 | 0.450 | ||
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.449 | ||
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.448 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.447 | ||
| ZNF746 | zinc finger protein 746 | 0.444 | ||
| HDAC7 | histone deacetylase 7 | 0.443 | ||
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.438 | ||
| BTRC | beta-transducin repeat containing | 0.436 | Fly | |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.426 | ||
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.424 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.424 | Human Mouse | |
| NCF1 | neutrophil cytosolic factor 1 | 0.423 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.421 | ||
| BCR | breakpoint cluster region | 0.420 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.420 | ||
| ARHGAP1 | Rho GTPase activating protein 1 | 0.412 | ||
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) | 0.412 | Human | |
| UBC | ubiquitin C | 0.410 | ||
| RIN2 | Ras and Rab interactor 2 | 0.409 | ||
| CTTN | cortactin | 0.400 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.397 | ||
| TFF1 | trefoil factor 1 | 0.396 | ||
| EPAS1 | endothelial PAS domain protein 1 | 0.393 | ||
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.385 | ||
| ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.384 | ||
| DOCK1 | dedicator of cytokinesis 1 | 0.382 | ||
| SORBS1 | sorbin and SH3 domain containing 1 | 0.381 | Mouse | |
| PRPF4B | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 0.381 | ||
| IRS4 | insulin receptor substrate 4 | 0.379 | Human Fly | |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.374 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.374 | Human Mouse | |
| DLG4 | discs, large homolog 4 (Drosophila) | 0.374 | Fly | |
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.373 | ||
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.372 | ||
| TTR | transthyretin | 0.369 | ||
| CLASP1 | cytoplasmic linker associated protein 1 | 0.367 | ||
| NGF | nerve growth factor (beta polypeptide) | 0.366 | Human | |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.365 | Fly | |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.364 | ||
| MPDZ | multiple PDZ domain protein | 0.364 | ||
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.359 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.357 | Fly | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.356 | ||
| CSHL1 | chorionic somatomammotropin hormone-like 1 | 0.351 | Human | |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.349 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.349 | Rat | |
| CSK | c-src tyrosine kinase | 0.348 | ||
| BLK | B lymphoid tyrosine kinase | 0.348 | ||
| CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.345 | ||
| MBP | myelin basic protein | 0.344 | ||
| PLAT | plasminogen activator, tissue | 0.344 | Human Mouse | |
| FGF2 | fibroblast growth factor 2 (basic) | 0.344 | ||
| BMP4 | bone morphogenetic protein 4 | 0.343 | Human | |
| CDK17 | cyclin-dependent kinase 17 | 0.342 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.342 | ||
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.340 | Mouse | |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.338 | ||
| RIN1 | Ras and Rab interactor 1 | 0.337 | ||
| YBX1 | Y box binding protein 1 | 0.337 | ||
| C1QC | complement component 1, q subcomponent, C chain | 0.336 | Human | |
| FSTL1 | follistatin-like 1 | 0.334 | ||
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.333 | ||
| TNS3 | tensin 3 | 0.332 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.332 | ||
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.330 | ||
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.329 | ||
| ABI2 | abl-interactor 2 | 0.327 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.327 | Fly | |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.325 | ||
| HDAC4 | histone deacetylase 4 | 0.323 | ||
| SNX9 | sorting nexin 9 | 0.323 | ||
| CAV2 | caveolin 2 | 0.322 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.320 | ||
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.320 | ||
| GRAP2 | GRB2-related adaptor protein 2 | 0.318 | Human Fly | |
| ABI1 | abl-interactor 1 | 0.318 | ||
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.318 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.316 | ||
| EGF | epidermal growth factor | 0.315 | ||
| DUSP3 | dual specificity phosphatase 3 | 0.312 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.309 | ||
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.309 | ||
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.309 | ||
| ATXN3 | ataxin 3 | 0.305 | ||
| EIF4E | eukaryotic translation initiation factor 4E | 0.304 | ||
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.302 | ||
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.300 | ||
| FGB | fibrinogen beta chain | 0.299 | Human | |
| SORT1 | sortilin 1 | 0.297 | ||
| TLN1 | talin 1 | 0.294 | ||
| APOA1 | apolipoprotein A-I | 0.293 | ||
| ACVR1 | activin A receptor, type I | 0.291 | ||
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.291 | ||
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.291 | ||
| FBLN5 | fibulin 5 | 0.290 | Human | |
| FBN1 | fibrillin 1 | 0.284 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.284 | ||
| GRN | granulin | 0.283 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.280 | ||
| CREB1 | cAMP responsive element binding protein 1 | 0.279 | ||
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.278 | ||
| PUM2 | pumilio homolog 2 (Drosophila) | 0.273 | Fly | |
| FGF4 | fibroblast growth factor 4 | 0.272 | ||
| EIF2C4 | eukaryotic translation initiation factor 2C, 4 | 0.272 | ||
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.272 | Human Fly | |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.270 | ||
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.267 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.262 | ||
| EPHA3 | EPH receptor A3 | 0.258 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.255 | Mouse | |
| SNTA1 | syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) | 0.254 | ||
| CISH | cytokine inducible SH2-containing protein | 0.254 | Human | |
| APC | adenomatous polyposis coli | 0.254 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.252 | Mouse | |
| FGF10 | fibroblast growth factor 10 | 0.250 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.250 | ||
| HIC1 | hypermethylated in cancer 1 | 0.247 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.247 | Human | |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.246 | ||
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.245 | ||
| BAIAP2 | BAI1-associated protein 2 | 0.241 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.240 | ||
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.237 | Human | |
| CTGF | connective tissue growth factor | 0.235 | Mouse | |
| COL2A1 | collagen, type II, alpha 1 | 0.234 | ||
| TGFB2 | transforming growth factor, beta 2 | 0.234 | Human | |
| KIF1B | kinesin family member 1B | 0.234 | Human | |
| RAB6A | RAB6A, member RAS oncogene family | 0.229 | ||
| TSG101 | tumor susceptibility gene 101 | 0.228 | ||
| SKIL | SKI-like oncogene | 0.228 | ||
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.227 | Mouse | |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.224 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.222 | ||
| EPHA7 | EPH receptor A7 | 0.222 | ||
| UBQLN1 | ubiquilin 1 | 0.221 | ||
| NGFR | nerve growth factor receptor | 0.218 | Mouse | |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.218 | ||
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.216 | Human | |
| ITGA7 | integrin, alpha 7 | 0.216 | ||
| DCN | decorin | 0.213 | ||
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.211 | Human | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.208 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.208 | ||
| DOK6 | docking protein 6 | 0.207 | Human | |
| SOCS2 | suppressor of cytokine signaling 2 | 0.207 | ||
| PRNP | prion protein | 0.206 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.203 | ||
| NOXA1 | NADPH oxidase activator 1 | 0.203 | ||
| SH2D2A | SH2 domain containing 2A | 0.202 | ||
| BMP1 | bone morphogenetic protein 1 | 0.201 | Fly | |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.200 | ||
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.199 | ||
| FKBP8 | FK506 binding protein 8, 38kDa | 0.198 | ||
| ACTB | actin, beta | 0.198 | ||
| FOXO1 | forkhead box O1 | 0.197 | Human Mouse Worm Fly | |
| MED28 | mediator complex subunit 28 | 0.197 | ||
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.195 | ||
| PSAP | prosaposin | 0.195 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.195 | ||
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.194 | ||
| SSTR3 | somatostatin receptor 3 | 0.193 | ||
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.193 | ||
| SRSF10 | serine/arginine-rich splicing factor 10 | 0.193 | ||
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.193 | Human | |
| EPHB2 | EPH receptor B2 | 0.191 | Human Mouse | |
| CD28 | CD28 molecule | 0.191 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.190 | Human Zebrafish Mouse | |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.189 | ||
| PBK | PDZ binding kinase | 0.189 | ||
| EFNA5 | ephrin-A5 | 0.189 | ||
| BLNK | B-cell linker | 0.189 | ||
| FBXO7 | F-box protein 7 | 0.185 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.185 | ||
| LAMB2 | laminin, beta 2 (laminin S) | 0.184 | ||
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.183 | ||
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.183 | Human | |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 0.183 | ||
| MED15 | mediator complex subunit 15 | 0.183 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.183 | ||
| PPP1R12A | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 0.182 | ||
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.182 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.181 | ||
| RASAL2 | RAS protein activator like 2 | 0.180 | Human | |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.179 | ||
| DSG2 | desmoglein 2 | 0.177 | ||
| BMP2 | bone morphogenetic protein 2 | 0.176 | ||
| SH2B3 | SH2B adaptor protein 3 | 0.174 | Fly | |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.173 | ||
| SLIT2 | slit homolog 2 (Drosophila) | 0.172 | ||
| LPXN | leupaxin | 0.172 | Human | |
| PGF | placental growth factor | 0.171 | Human | |
| SAMD4A | sterile alpha motif domain containing 4A | 0.171 | ||
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.171 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.171 | ||
| NRG1 | neuregulin 1 | 0.170 | ||
| MAPT | microtubule-associated protein tau | 0.170 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.169 | Human | |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.169 | ||
| CSH2 | chorionic somatomammotropin hormone 2 | 0.169 | Human | |
| DAPK1 | death-associated protein kinase 1 | 0.168 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.168 | ||
| COL13A1 | collagen, type XIII, alpha 1 | 0.168 | ||
| ANGPT2 | angiopoietin 2 | 0.167 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.166 | Mouse | |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.165 | ||
| FGF7 | fibroblast growth factor 7 | 0.164 | ||
| LOXL2 | lysyl oxidase-like 2 | 0.164 | ||
| MEGF6 | multiple EGF-like-domains 6 | 0.162 | ||
| AXIN1 | axin 1 | 0.162 | ||
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.162 | ||
| TMSB4X | thymosin beta 4, X-linked | 0.162 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.161 | Mouse | |
| CEP250 | centrosomal protein 250kDa | 0.161 | ||
| NRP2 | neuropilin 2 | 0.159 | Human Zebrafish | |
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.158 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.158 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.158 | ||
| SQSTM1 | sequestosome 1 | 0.155 | ||
| LTK | leukocyte receptor tyrosine kinase | 0.155 | Human | |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.154 | ||
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.153 | ||
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.153 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.152 | ||
| KIF1C | kinesin family member 1C | 0.152 | Human | |
| ENG | endoglin | 0.152 | ||
| FGFR4 | fibroblast growth factor receptor 4 | 0.151 | ||
| A2M | alpha-2-macroglobulin | 0.151 | ||
| TBXA2R | thromboxane A2 receptor | 0.150 | ||
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.150 | ||
| SOCS5 | suppressor of cytokine signaling 5 | 0.150 | ||
| CD34 | CD34 molecule | 0.150 | ||
| IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.150 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.149 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.149 | ||
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.149 | ||
| RALBP1 | ralA binding protein 1 | 0.149 | ||
| SYNRG | synergin, gamma | 0.148 | ||
| SOX2 | SRY (sex determining region Y)-box 2 | 0.147 | ||
| C1QB | complement component 1, q subcomponent, B chain | 0.147 | Human | |
| TWIST2 | twist homolog 2 (Drosophila) | 0.145 | ||
| COL5A1 | collagen, type V, alpha 1 | 0.144 | ||
| EFNB1 | ephrin-B1 | 0.143 | Human | |
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.143 | ||
| HSPB2 | heat shock 27kDa protein 2 | 0.143 | ||
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 0.143 | ||
| PDGFC | platelet derived growth factor C | 0.141 | ||
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.141 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.140 | ||
| GAS1 | growth arrest-specific 1 | 0.139 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.139 | ||
| GDNF | glial cell derived neurotrophic factor | 0.139 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.139 | ||
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | 0.138 | ||
| SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.138 | ||
| CPD | carboxypeptidase D | 0.138 | ||
| SMAD6 | SMAD family member 6 | 0.138 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.138 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.137 | ||
| SH3GL3 | SH3-domain GRB2-like 3 | 0.136 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.136 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.135 | ||
| TEX11 | testis expressed 11 | 0.135 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.134 | ||
| C19orf50 | chromosome 19 open reading frame 50 | 0.134 | ||
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.134 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.134 | ||
| NTF3 | neurotrophin 3 | 0.133 | ||
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 | 0.133 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.132 | ||
| DPYSL4 | dihydropyrimidinase-like 4 | 0.132 | ||
| FGF18 | fibroblast growth factor 18 | 0.132 | Human | |
| CD2AP | CD2-associated protein | 0.132 | ||
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.131 | ||
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.131 | ||
| WNT11 | wingless-type MMTV integration site family, member 11 | 0.130 | Human | |
| RXRA | retinoid X receptor, alpha | 0.130 | ||
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.129 | ||
| SPRR2A | small proline-rich protein 2A | 0.128 | ||
| SCHIP1 | schwannomin interacting protein 1 | 0.127 | Mouse | |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.127 | ||
| TENC1 | tensin like C1 domain containing phosphatase (tensin 2) | 0.127 | ||
| CD9 | CD9 molecule | 0.127 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.126 | Mouse | |
| MAPK11 | mitogen-activated protein kinase 11 | 0.126 | Human | |
| ACAN | aggrecan | 0.126 | ||
| EZR | ezrin | 0.126 | ||
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 0.125 | ||
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.124 | Fly | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.124 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.124 | Human | |
| VEGFC | vascular endothelial growth factor C | 0.124 | Human Mouse Rat | |
| IRF3 | interferon regulatory factor 3 | 0.123 | ||
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.122 | ||
| CSF1 | colony stimulating factor 1 (macrophage) | 0.122 | ||
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.122 | ||
| HSPB8 | heat shock 22kDa protein 8 | 0.122 | Human | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.121 | ||
| ANGPT1 | angiopoietin 1 | 0.120 | ||
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.120 | ||
| MPRIP | myosin phosphatase Rho interacting protein | 0.120 | ||
| DUSP9 | dual specificity phosphatase 9 | 0.120 | ||
| XPOT | exportin, tRNA (nuclear export receptor for tRNAs) | 0.119 | ||
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.119 | ||
| DAB1 | disabled homolog 1 (Drosophila) | 0.119 | ||
| ARRB1 | arrestin, beta 1 | 0.119 | ||
| LIN28B | lin-28 homolog B (C. elegans) | 0.118 | ||
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.118 | ||
| DUSP5 | dual specificity phosphatase 5 | 0.118 | ||
| ZMYM4 | zinc finger, MYM-type 4 | 0.117 | ||
| SCRT1 | scratch homolog 1, zinc finger protein (Drosophila) | 0.117 | ||
| ATG13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.116 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.116 | ||
| PALM | paralemmin | 0.116 | ||
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.116 | ||
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.115 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.115 | ||
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.115 | Mouse Rat | |
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.114 | ||
| BDNF | brain-derived neurotrophic factor | 0.114 | Human | |
| PLAU | plasminogen activator, urokinase | 0.114 | Human | |
| NOS1 | nitric oxide synthase 1 (neuronal) | 0.113 | ||
| EEF2K | eukaryotic elongation factor-2 kinase | 0.113 | ||
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.113 | ||
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.112 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.112 | ||
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.112 | Rat | |
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.112 | ||
| FGG | fibrinogen gamma chain | 0.112 | ||
| FLT3 | fms-related tyrosine kinase 3 | 0.111 | Human | |
| SH3BP2 | SH3-domain binding protein 2 | 0.111 | ||
| ATXN1 | ataxin 1 | 0.111 | Mouse | |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.111 | ||
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.111 | ||
| CLNK | cytokine-dependent hematopoietic cell linker | 0.110 | Mouse | |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.110 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.110 | ||
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.110 | ||
| COL8A1 | collagen, type VIII, alpha 1 | 0.110 | ||
| SFN | stratifin | 0.110 | ||
| HOXA1 | homeobox A1 | 0.109 | ||
| ECM1 | extracellular matrix protein 1 | 0.109 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.109 | ||
| JAG2 | jagged 2 | 0.108 | ||
| EFNB2 | ephrin-B2 | 0.108 | ||
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 0.108 | Human | |
| RUNX2 | runt-related transcription factor 2 | 0.108 | Mouse | |
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.107 | Human | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.107 | ||
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.107 | ||
| RGS4 | regulator of G-protein signaling 4 | 0.107 | ||
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.107 | Human | |
| IL1RAP | interleukin 1 receptor accessory protein | 0.106 | ||
| EML3 | echinoderm microtubule associated protein like 3 | 0.106 | ||
| STAB1 | stabilin 1 | 0.106 | ||
| HAS2 | hyaluronan synthase 2 | 0.106 | ||
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.106 | ||
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 0.105 | Human | |
| LY6G6F | lymphocyte antigen 6 complex, locus G6F | 0.105 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.105 | ||
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.104 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.104 | ||
| SIRT1 | sirtuin 1 | 0.104 | ||
| OCRL | oculocerebrorenal syndrome of Lowe | 0.104 | Human | |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.104 | ||
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) | 0.104 | ||
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.103 | Zebrafish Fly | |
| STC1 | stanniocalcin 1 | 0.103 | ||
| RHOU | ras homolog gene family, member U | 0.103 | ||
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.103 | ||
| ANXA1 | annexin A1 | 0.102 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.102 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.102 | Fly | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.101 | ||
| ARRDC3 | arrestin domain containing 3 | 0.101 | ||
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.101 | ||
| PTH1R | parathyroid hormone 1 receptor | 0.101 | ||
| NID1 | nidogen 1 | 0.101 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.100 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.100 | ||
| TSC1 | tuberous sclerosis 1 | 0.099 | Fly | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.099 | ||
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) | 0.099 | ||
| STAB2 | stabilin 2 | 0.098 | ||
| INHBA | inhibin, beta A | 0.098 | ||
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.098 | ||
| SMC6 | structural maintenance of chromosomes 6 | 0.098 | ||
| INHBB | inhibin, beta B | 0.098 | ||
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.098 | Human | |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 0.097 | ||
| WNT7A | wingless-type MMTV integration site family, member 7A | 0.097 | Human | |
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.097 | Fly | |
| ADRA1D | adrenergic, alpha-1D-, receptor | 0.096 | ||
| SESN2 | sestrin 2 | 0.096 | ||
| XPO7 | exportin 7 | 0.096 | ||
| SPDEF | SAM pointed domain containing ets transcription factor | 0.096 | ||
| ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.096 | Fly | |
| TNPO1 | transportin 1 | 0.096 | ||
| PRKCE | protein kinase C, epsilon | 0.096 | Worm | |
| ZNF295 | zinc finger protein 295 | 0.095 | ||
| FZD5 | frizzled homolog 5 (Drosophila) | 0.095 | ||
| SH2B2 | SH2B adaptor protein 2 | 0.095 | ||
| LBR | lamin B receptor | 0.095 | ||
| TM4SF1 | transmembrane 4 L six family member 1 | 0.094 | ||
| HMOX2 | heme oxygenase (decycling) 2 | 0.094 | ||
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.094 | ||
| FGFR3 | fibroblast growth factor receptor 3 | 0.094 | ||
| PLXDC1 | plexin domain containing 1 | 0.094 | ||
| PHF3 | PHD finger protein 3 | 0.093 | ||
| NF2 | neurofibromin 2 (merlin) | 0.093 | ||
| NOTCH2 | notch 2 | 0.093 | ||
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | 0.092 | Human | |
| DMPK | dystrophia myotonica-protein kinase | 0.092 | ||
| CUL2 | cullin 2 | 0.092 | ||
| LOXL1 | lysyl oxidase-like 1 | 0.092 | ||
| GRM8 | glutamate receptor, metabotropic 8 | 0.091 | ||
| FGF3 | fibroblast growth factor 3 | 0.091 | ||
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 | 0.091 | ||
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.091 | ||
| WISP1 | WNT1 inducible signaling pathway protein 1 | 0.091 | ||
| PDE10A | phosphodiesterase 10A | 0.090 | ||
| TNS4 | tensin 4 | 0.090 | ||
| PRKCZ | protein kinase C, zeta | 0.090 | ||
| RDX | radixin | 0.089 | ||
| DOCK7 | dedicator of cytokinesis 7 | 0.089 | ||
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.089 | ||
| TNC | tenascin C | 0.089 | ||
| KCNMA1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.089 | ||
| HCK | hemopoietic cell kinase | 0.089 | ||
| STK10 | serine/threonine kinase 10 | 0.089 | ||
| SYNJ1 | synaptojanin 1 | 0.088 | ||
| SCARF2 | scavenger receptor class F, member 2 | 0.088 | ||
| FOXF2 | forkhead box F2 | 0.088 | ||
| TNRC6B | trinucleotide repeat containing 6B | 0.088 | ||
| RHOG | ras homolog gene family, member G (rho G) | 0.088 | Human | |
| SH2D1A | SH2 domain containing 1A | 0.087 | ||
| KLF9 | Kruppel-like factor 9 | 0.087 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.087 | Human | |
| COASY | CoA synthase | 0.087 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.087 | ||
| ATXN1L | ataxin 1-like | 0.086 | ||
| MAGOHB | mago-nashi homolog B (Drosophila) | 0.086 | ||
| TPP1 | tripeptidyl peptidase I | 0.086 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.086 | ||
| ADAM10 | ADAM metallopeptidase domain 10 | 0.086 | ||
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.085 | ||
| ARHGAP9 | Rho GTPase activating protein 9 | 0.085 | ||
| RELN | reelin | 0.085 | ||
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.085 | ||
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.084 | ||
| TF | transferrin | 0.084 | ||
| MFN1 | mitofusin 1 | 0.084 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.084 | ||
| MYO10 | myosin X | 0.084 | ||
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.084 | ||
| IHH | Indian hedgehog | 0.083 | ||
| NACAD | NAC alpha domain containing | 0.083 | ||
| EFCAB4B | EF-hand calcium binding domain 4B | 0.083 | ||
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.083 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.083 | ||
| EDN1 | endothelin 1 | 0.082 | ||
| GAS6 | growth arrest-specific 6 | 0.082 | ||
| EFNA1 | ephrin-A1 | 0.082 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.082 | ||
| CHMP4B | chromatin modifying protein 4B | 0.082 | ||
| RAP1A | RAP1A, member of RAS oncogene family | 0.082 | ||
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.081 | ||
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.081 | Mouse | |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.081 | ||
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.081 | ||
| RNF38 | ring finger protein 38 | 0.081 | ||
| PDS5A | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.081 | ||
| LOX | lysyl oxidase | 0.081 | ||
| SCARB2 | scavenger receptor class B, member 2 | 0.080 | ||
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.080 | ||
| PTEN | phosphatase and tensin homolog | 0.080 | Rat Fly | |
| ZNF775 | zinc finger protein 775 | 0.080 | ||
| S100A4 | S100 calcium binding protein A4 | 0.080 | ||
| CRHR1 | corticotropin releasing hormone receptor 1 | 0.080 | ||
| IL11 | interleukin 11 | 0.080 | ||
| ARHGAP5 | Rho GTPase activating protein 5 | 0.080 | ||
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.080 | Human | |
| KLB | klotho beta | 0.080 | ||
| OR2AG1 | olfactory receptor, family 2, subfamily AG, member 1 | 0.080 | ||
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) | 0.079 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.079 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.078 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.078 | ||
| RBPMS | RNA binding protein with multiple splicing | 0.078 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.078 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.078 | ||
| GH2 | growth hormone 2 | 0.077 | Human | |
| AKAP2 | A kinase (PRKA) anchor protein 2 | 0.077 | ||
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.077 | ||
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 0.077 | ||
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.077 | Worm | |
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.077 | ||
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.077 | ||
| PLEK | pleckstrin | 0.077 | ||
| CPNE6 | copine VI (neuronal) | 0.077 | ||
| GPR124 | G protein-coupled receptor 124 | 0.076 | Mouse | |
| KCNQ2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.076 | ||
| ZUFSP | zinc finger with UFM1-specific peptidase domain | 0.076 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.076 | ||
| HTRA1 | HtrA serine peptidase 1 | 0.076 | Zebrafish | |
| ADRB1 | adrenergic, beta-1-, receptor | 0.075 | Human | |
| ANGPTL2 | angiopoietin-like 2 | 0.075 | Human | |
| SLIT1 | slit homolog 1 (Drosophila) | 0.075 | ||
| EPHA1 | EPH receptor A1 | 0.075 | ||
| STAG1 | stromal antigen 1 | 0.075 | ||
| WNT2 | wingless-type MMTV integration site family member 2 | 0.075 | Human | |
| RNF126 | ring finger protein 126 | 0.075 | ||
| ZNF71 | zinc finger protein 71 | 0.075 | ||
| NOTCH3 | notch 3 | 0.074 | ||
| ITGB5 | integrin, beta 5 | 0.074 | ||
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.074 | ||
| LRPPRC | leucine-rich PPR-motif containing | 0.074 | ||
| RLN3 | relaxin 3 | 0.074 | ||
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.074 | ||
| ZFPM2 | zinc finger protein, multitype 2 | 0.074 | Fly | |
| STMN2 | stathmin-like 2 | 0.073 | ||
| PPP1R14A | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 0.073 | ||
| MAF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 0.073 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.073 | ||
| LAMP1 | lysosomal-associated membrane protein 1 | 0.073 | ||
| BMX | BMX non-receptor tyrosine kinase | 0.073 | Human | |
| MEGF11 | multiple EGF-like-domains 11 | 0.073 | ||
| DOK5 | docking protein 5 | 0.072 | Human Mouse | |
| PLAUR | plasminogen activator, urokinase receptor | 0.072 | ||
| NTF4 | neurotrophin 4 | 0.072 | Human | |
| CD248 | CD248 molecule, endosialin | 0.072 | ||
| ITM2B | integral membrane protein 2B | 0.072 | ||
| CAPRIN1 | cell cycle associated protein 1 | 0.072 | ||
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.071 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.071 | ||
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 0.071 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.071 | ||
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit | 0.071 | ||
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.071 | ||
| MYOD1 | myogenic differentiation 1 | 0.071 | ||
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | 0.071 | ||
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.071 | ||
| IDUA | iduronidase, alpha-L- | 0.071 | ||
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.071 | ||
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.070 | ||
| CAPN1 | calpain 1, (mu/I) large subunit | 0.070 | ||
| GMFB | glia maturation factor, beta | 0.070 | ||
| SOX9 | SRY (sex determining region Y)-box 9 | 0.070 | Mouse | |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.070 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.070 | ||
| NCAM1 | neural cell adhesion molecule 1 | 0.070 | Fly | |
| SFRP5 | secreted frizzled-related protein 5 | 0.070 | ||
| EXOC5 | exocyst complex component 5 | 0.070 | ||
| SYNPO | synaptopodin | 0.070 |