Process View
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "proteasomal protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 1.000 | Yeast | |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 1.000 | ||
| CUL1 | cullin 1 | 1.000 | ||
| UBC | ubiquitin C | 1.000 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 1.000 | Yeast | |
| TP53 | tumor protein p53 | 1.000 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.999 | ||
| VCP | valosin containing protein | 0.999 | ||
| CUL3 | cullin 3 | 0.999 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.998 | ||
| RNF11 | ring finger protein 11 | 0.997 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.995 | Human | |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.994 | Yeast | |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.993 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.989 | ||
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.989 | ||
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.988 | Yeast | |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.988 | Yeast | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.987 | ||
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.987 | Yeast | |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.985 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.984 | ||
| UBQLN1 | ubiquilin 1 | 0.981 | Human | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.980 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.980 | ||
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.977 | Yeast | |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.976 | ||
| BTRC | beta-transducin repeat containing | 0.975 | ||
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.974 | Yeast | |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.973 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.972 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.967 | Zebrafish | |
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.963 | Yeast Mouse | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.957 | Rat | |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.954 | Yeast | |
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.954 | Fly | |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.952 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.950 | ||
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.948 | ||
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.938 | Yeast | |
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.933 | Mouse Fly | |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.932 | Yeast | |
| PLK1 | polo-like kinase 1 | 0.931 | ||
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.927 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.923 | Mouse Fly | |
| XIAP | X-linked inhibitor of apoptosis | 0.923 | Human | |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.920 | ||
| SMAD2 | SMAD family member 2 | 0.920 | Human | |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.918 | ||
| YY1 | YY1 transcription factor | 0.908 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.900 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.899 | ||
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.896 | Yeast | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.895 | ||
| CCNB1 | cyclin B1 | 0.894 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.893 | ||
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.890 | Yeast | |
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.886 | ||
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.882 | ||
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.881 | Yeast | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.878 | Human | |
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.852 | Human | |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.842 | Yeast | |
| SMAD4 | SMAD family member 4 | 0.837 | Human | |
| ATXN3 | ataxin 3 | 0.837 | Mouse | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.833 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.830 | ||
| POMP | proteasome maturation protein | 0.825 | ||
| SQSTM1 | sequestosome 1 | 0.809 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.807 | ||
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.797 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.796 | ||
| RB1 | retinoblastoma 1 | 0.791 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.785 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.785 | ||
| CCNA2 | cyclin A2 | 0.775 | ||
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.770 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.763 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.748 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.743 | Human Yeast | |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.739 | Worm | |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.730 | Fly | |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.721 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.719 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.706 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.705 | Mouse | |
| CREBBP | CREB binding protein | 0.702 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.702 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.699 | ||
| HDAC1 | histone deacetylase 1 | 0.698 | ||
| FBXW2 | F-box and WD repeat domain containing 2 | 0.682 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.671 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.656 | Human | |
| FBXO5 | F-box protein 5 | 0.646 | ||
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.639 | Human | |
| BRCA1 | breast cancer 1, early onset | 0.637 | ||
| SMAD1 | SMAD family member 1 | 0.632 | Human | |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.628 | ||
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.627 | ||
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.623 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.618 | ||
| AMFR | autocrine motility factor receptor | 0.615 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.612 | Yeast | |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.612 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.607 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.604 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.601 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.598 | ||
| PJA2 | praja ring finger 2 | 0.593 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.586 | Yeast | |
| CSNK1E | casein kinase 1, epsilon | 0.579 | Mouse Fly | |
| RNF5 | ring finger protein 5 | 0.573 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.568 | Human | |
| MKRN1 | makorin ring finger protein 1 | 0.550 | ||
| EP300 | E1A binding protein p300 | 0.549 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.537 | ||
| DERL1 | Der1-like domain family, member 1 | 0.536 | ||
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.506 | ||
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.506 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.502 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.498 | Fly | |
| SMAD5 | SMAD family member 5 | 0.494 | Human | |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.490 | ||
| RYBP | RING1 and YY1 binding protein | 0.489 | Fly | |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.488 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.484 | ||
| DAXX | death-domain associated protein | 0.480 | ||
| UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.472 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.467 | ||
| TCP1 | t-complex 1 | 0.459 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.457 | ||
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.456 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.455 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.449 | ||
| TRIM39 | tripartite motif containing 39 | 0.438 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.433 | ||
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.427 | ||
| CUL5 | cullin 5 | 0.423 | ||
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.422 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.417 | Yeast | |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.410 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.408 | Human | |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.405 | ||
| FBXW5 | F-box and WD repeat domain containing 5 | 0.404 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.403 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.402 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.394 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.389 | ||
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.388 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.383 | ||
| FAF2 | Fas associated factor family member 2 | 0.383 | ||
| ARRB1 | arrestin, beta 1 | 0.382 | ||
| CCNB2 | cyclin B2 | 0.380 | ||
| SSR1 | signal sequence receptor, alpha | 0.373 | ||
| RNF111 | ring finger protein 111 | 0.364 | ||
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.363 | ||
| TRIM43 | tripartite motif containing 43 | 0.361 | ||
| RPN1 | ribophorin I | 0.358 | ||
| PSEN1 | presenilin 1 | 0.358 | Mouse | |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.357 | ||
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.356 | Yeast | |
| KLHL12 | kelch-like 12 (Drosophila) | 0.354 | Human | |
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.349 | Human | |
| KEAP1 | kelch-like ECH-associated protein 1 | 0.347 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.340 | Human Yeast | |
| RANBP2 | RAN binding protein 2 | 0.338 | ||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.337 | Human Yeast Mouse | |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.334 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.328 | ||
| SMAD3 | SMAD family member 3 | 0.325 | Human | |
| BAG2 | BCL2-associated athanogene 2 | 0.323 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.319 | ||
| ACTB | actin, beta | 0.318 | ||
| NBR1 | neighbor of BRCA1 gene 1 | 0.316 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.315 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.315 | ||
| AXIN1 | axin 1 | 0.308 | Mouse | |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.303 | ||
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.302 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.299 | ||
| SKIL | SKI-like oncogene | 0.294 | ||
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.291 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.291 | Human | |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.285 | ||
| HSPA8 | heat shock 70kDa protein 8 | 0.280 | ||
| IER3 | immediate early response 3 | 0.280 | ||
| RNF31 | ring finger protein 31 | 0.273 | ||
| SMN1 | survival of motor neuron 1, telomeric | 0.272 | ||
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.269 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.264 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.261 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.261 | ||
| SMAD7 | SMAD family member 7 | 0.253 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.250 | Mouse Fly | |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.248 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.246 | ||
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.246 | ||
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.244 | ||
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.244 | ||
| JUN | jun proto-oncogene | 0.239 | ||
| FBXO33 | F-box protein 33 | 0.239 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.238 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.238 | ||
| CACYBP | calcyclin binding protein | 0.235 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.233 | ||
| FEN1 | flap structure-specific endonuclease 1 | 0.233 | ||
| ZNRF1 | zinc and ring finger 1 | 0.230 | Mouse | |
| HSPA4 | heat shock 70kDa protein 4 | 0.229 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.228 | Human | |
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.226 | ||
| CUL4B | cullin 4B | 0.223 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.220 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.220 | ||
| KCTD10 | potassium channel tetramerisation domain containing 10 | 0.220 | Human | |
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.219 | Human Yeast | |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.218 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.217 | ||
| ATP13A2 | ATPase type 13A2 | 0.216 | ||
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.216 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.213 | ||
| RNF126 | ring finger protein 126 | 0.212 | ||
| BFAR | bifunctional apoptosis regulator | 0.211 | ||
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.211 | ||
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.211 | ||
| ZNF496 | zinc finger protein 496 | 0.209 | ||
| UBXN7 | UBX domain protein 7 | 0.208 | Yeast | |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.203 | Human | |
| CUL4A | cullin 4A | 0.201 | Mouse | |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.201 | Human | |
| IGF1R | insulin-like growth factor 1 receptor | 0.199 | ||
| FBXO7 | F-box protein 7 | 0.197 | ||
| FBXO3 | F-box protein 3 | 0.197 | ||
| EPOR | erythropoietin receptor | 0.196 | ||
| TFDP1 | transcription factor Dp-1 | 0.192 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.190 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.188 | Human | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.187 | ||
| SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.186 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.184 | Human | |
| TBP | TATA box binding protein | 0.184 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.182 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.181 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.179 | ||
| PTEN | phosphatase and tensin homolog | 0.179 | ||
| MED21 | mediator complex subunit 21 | 0.179 | ||
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.179 | ||
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.178 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.178 | ||
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.177 | ||
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.176 | Human | |
| NBN | nibrin | 0.176 | ||
| UBXN2A | UBX domain protein 2A | 0.174 | ||
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.173 | ||
| MIB1 | mindbomb homolog 1 (Drosophila) | 0.173 | ||
| AR | androgen receptor | 0.173 | ||
| WNK4 | WNK lysine deficient protein kinase 4 | 0.173 | ||
| WDR26 | WD repeat domain 26 | 0.172 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.171 | Human | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.171 | ||
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.171 | ||
| SELS | selenoprotein S | 0.170 | ||
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 0.169 | Human | |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.168 | ||
| MBD3 | methyl-CpG binding domain protein 3 | 0.168 | ||
| HDAC6 | histone deacetylase 6 | 0.167 | ||
| TRIM27 | tripartite motif containing 27 | 0.167 | ||
| TRIM63 | tripartite motif containing 63 | 0.166 | Human Mouse | |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.166 | ||
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.165 | ||
| SMC6 | structural maintenance of chromosomes 6 | 0.165 | ||
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.163 | ||
| ATF3 | activating transcription factor 3 | 0.162 | ||
| RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.162 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.161 | ||
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.160 | ||
| TRIM28 | tripartite motif containing 28 | 0.160 | ||
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.160 | ||
| RNF114 | ring finger protein 114 | 0.159 | ||
| PPP5C | protein phosphatase 5, catalytic subunit | 0.158 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.158 | ||
| CLOCK | clock homolog (mouse) | 0.158 | Mouse | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.157 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.157 | ||
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.156 | Yeast | |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.153 | Mouse | |
| UBE3A | ubiquitin protein ligase E3A | 0.152 | ||
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.148 | ||
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.146 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.144 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.143 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.142 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.142 | ||
| ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.140 | ||
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.138 | Worm Fly | |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.138 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.138 | ||
| HDAC2 | histone deacetylase 2 | 0.137 | ||
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.137 | Yeast | |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.136 | ||
| BAG6 | BCL2-associated athanogene 6 | 0.135 | Mouse | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.134 | ||
| CANX | calnexin | 0.132 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.132 | ||
| MTA1 | metastasis associated 1 | 0.132 | ||
| BTBD2 | BTB (POZ) domain containing 2 | 0.131 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.131 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.131 | ||
| SFN | stratifin | 0.131 | ||
| USP15 | ubiquitin specific peptidase 15 | 0.130 | Human | |
| AP1M1 | adaptor-related protein complex 1, mu 1 subunit | 0.128 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.128 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.128 | ||
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.127 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.127 | ||
| CDK17 | cyclin-dependent kinase 17 | 0.126 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.126 | ||
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.125 | Mouse | |
| VPRBP | Vpr (HIV-1) binding protein | 0.125 | ||
| BRAP | BRCA1 associated protein | 0.125 | ||
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.124 | ||
| PBK | PDZ binding kinase | 0.124 | Mouse | |
| GABARAP | GABA(A) receptor-associated protein | 0.122 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.122 | ||
| NEURL4 | neuralized homolog 4 (Drosophila) | 0.121 | ||
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.121 | ||
| AURKB | aurora kinase B | 0.120 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.119 | Human | |
| RNF26 | ring finger protein 26 | 0.117 | ||
| BCL2L1 | BCL2-like 1 | 0.117 | ||
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.117 | ||
| TMEM173 | transmembrane protein 173 | 0.117 | ||
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.117 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.117 | ||
| UBXN1 | UBX domain protein 1 | 0.115 | ||
| PRNP | prion protein | 0.115 | ||
| NUDCD3 | NudC domain containing 3 | 0.114 | ||
| MYO6 | myosin VI | 0.114 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.113 | ||
| TRIM8 | tripartite motif containing 8 | 0.113 | ||
| GFM1 | G elongation factor, mitochondrial 1 | 0.113 | ||
| TXNL1 | thioredoxin-like 1 | 0.113 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.112 | ||
| ING2 | inhibitor of growth family, member 2 | 0.112 | ||
| TPBG | trophoblast glycoprotein | 0.111 | ||
| ADNP | activity-dependent neuroprotector homeobox | 0.111 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.110 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.109 | ||
| RXRB | retinoid X receptor, beta | 0.109 | ||
| TADA3 | transcriptional adaptor 3 | 0.109 | ||
| DAPK1 | death-associated protein kinase 1 | 0.109 | ||
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.108 | ||
| MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.108 | ||
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.108 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.108 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.106 | ||
| KCTD3 | potassium channel tetramerisation domain containing 3 | 0.106 | ||
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 0.106 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.106 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.106 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.105 | ||
| BECN1 | beclin 1, autophagy related | 0.105 | ||
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.104 | ||
| PML | promyelocytic leukemia | 0.104 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.103 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.103 | ||
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.103 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.103 | ||
| KDM1A | lysine (K)-specific demethylase 1A | 0.102 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.102 | ||
| RFK | riboflavin kinase | 0.102 | ||
| ANKRD17 | ankyrin repeat domain 17 | 0.102 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.101 | Human | |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.100 | ||
| MAGEA2 | melanoma antigen family A, 2 | 0.100 | ||
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.100 | Yeast | |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.100 | Yeast | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.100 | ||
| CAPRIN1 | cell cycle associated protein 1 | 0.099 | ||
| HDAC11 | histone deacetylase 11 | 0.099 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.099 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.098 | ||
| KIAA1033 | KIAA1033 | 0.098 | ||
| APC | adenomatous polyposis coli | 0.098 | ||
| KLHL2 | kelch-like 2, Mayven (Drosophila) | 0.098 | Human | |
| SEC24B | SEC24 family, member B (S. cerevisiae) | 0.097 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.097 | Yeast | |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.097 | ||
| MTDH | metadherin | 0.097 | ||
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.097 | ||
| KSR1 | kinase suppressor of ras 1 | 0.097 | Human | |
| GAA | glucosidase, alpha; acid | 0.096 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.096 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.096 | ||
| AHR | aryl hydrocarbon receptor | 0.096 | ||
| RNF168 | ring finger protein 168 | 0.095 | ||
| ANAPC10 | anaphase promoting complex subunit 10 | 0.095 | Yeast | |
| FYCO1 | FYVE and coiled-coil domain containing 1 | 0.095 | ||
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.095 | ||
| RHOB | ras homolog gene family, member B | 0.095 | ||
| CASC5 | cancer susceptibility candidate 5 | 0.094 | ||
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.094 | ||
| MYO1C | myosin IC | 0.093 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.093 | ||
| PPP6C | protein phosphatase 6, catalytic subunit | 0.093 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.093 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.093 | Human | |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.093 | ||
| MAP1S | microtubule-associated protein 1S | 0.092 | ||
| CUL2 | cullin 2 | 0.092 | Worm | |
| MED1 | mediator complex subunit 1 | 0.092 | ||
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.092 | ||
| RNF38 | ring finger protein 38 | 0.092 | ||
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.092 | ||
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.092 | ||
| STIP1 | stress-induced-phosphoprotein 1 | 0.092 | ||
| UBQLN4 | ubiquilin 4 | 0.092 | ||
| STAG1 | stromal antigen 1 | 0.092 | ||
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.092 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.092 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.091 | ||
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 0.090 | ||
| ZNF746 | zinc finger protein 746 | 0.090 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.090 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.090 | Mouse | |
| ARMC7 | armadillo repeat containing 7 | 0.090 | ||
| CSNK1D | casein kinase 1, delta | 0.090 | Mouse Fly | |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.090 | ||
| EEF2 | eukaryotic translation elongation factor 2 | 0.090 | ||
| DERL2 | Der1-like domain family, member 2 | 0.089 | ||
| RNF138 | ring finger protein 138 | 0.089 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.089 | ||
| MAP1B | microtubule-associated protein 1B | 0.089 | ||
| CDYL | chromodomain protein, Y-like | 0.089 | ||
| CARM1 | coactivator-associated arginine methyltransferase 1 | 0.088 | ||
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.088 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.088 | ||
| RNF4 | ring finger protein 4 | 0.087 | ||
| HERC2 | hect domain and RLD 2 | 0.087 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.087 | ||
| TRIM21 | tripartite motif containing 21 | 0.087 | ||
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.086 | ||
| CLTA | clathrin, light chain A | 0.085 | ||
| LIN28B | lin-28 homolog B (C. elegans) | 0.085 | ||
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.085 | ||
| SURF4 | surfeit 4 | 0.085 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.084 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.084 | ||
| RNF10 | ring finger protein 10 | 0.084 | ||
| TOR1AIP2 | torsin A interacting protein 2 | 0.084 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.084 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.083 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.083 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.083 | ||
| CEP76 | centrosomal protein 76kDa | 0.082 | ||
| CP110 | CP110 protein | 0.082 | ||
| CCND1 | cyclin D1 | 0.082 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.082 | ||
| GATAD2B | GATA zinc finger domain containing 2B | 0.082 | ||
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.082 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.082 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.081 | Human | |
| ETF1 | eukaryotic translation termination factor 1 | 0.081 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.081 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.081 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.080 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.080 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.080 | ||
| CBX5 | chromobox homolog 5 | 0.079 | ||
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.079 | ||
| UBE2K | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | 0.079 | Yeast Mouse | |
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.077 | ||
| MTA3 | metastasis associated 1 family, member 3 | 0.077 | Human | |
| BTBD10 | BTB (POZ) domain containing 10 | 0.077 | ||
| KBTBD7 | kelch repeat and BTB (POZ) domain containing 7 | 0.077 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.077 | Mouse | |
| DOCK7 | dedicator of cytokinesis 7 | 0.077 | ||
| COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.077 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.076 | ||
| PIAS3 | protein inhibitor of activated STAT, 3 | 0.076 | ||
| FBXO25 | F-box protein 25 | 0.076 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.076 | ||
| PRPF8 | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 0.076 | ||
| NDC80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.076 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.076 | ||
| SPAG9 | sperm associated antigen 9 | 0.076 | ||
| RBBP7 | retinoblastoma binding protein 7 | 0.075 | ||
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.075 | ||
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.075 | ||
| HIPK1 | homeodomain interacting protein kinase 1 | 0.075 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.074 | ||
| SPOP | speckle-type POZ protein | 0.074 | ||
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.074 | ||
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.074 | ||
| TOR1A | torsin family 1, member A (torsin A) | 0.074 | ||
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.074 | Mouse | |
| TRIM23 | tripartite motif containing 23 | 0.073 | ||
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.073 | ||
| BRD7 | bromodomain containing 7 | 0.073 | ||
| S100A4 | S100 calcium binding protein A4 | 0.073 | ||
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 0.073 | ||
| XBP1 | X-box binding protein 1 | 0.073 | Mouse | |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.072 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.072 | ||
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.072 | Human | |
| FAM83D | family with sequence similarity 83, member D | 0.072 | ||
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.071 | ||
| RAB21 | RAB21, member RAS oncogene family | 0.070 | ||
| FBXO4 | F-box protein 4 | 0.070 | ||
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.069 | ||
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.069 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.069 | ||
| EIF4E | eukaryotic translation initiation factor 4E | 0.069 | ||
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.069 | ||
| USP11 | ubiquitin specific peptidase 11 | 0.069 | Human | |
| RHOA | ras homolog gene family, member A | 0.069 | ||
| OTUD5 | OTU domain containing 5 | 0.069 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.069 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.068 | ||
| RNF14 | ring finger protein 14 | 0.068 | ||
| CDKN2AIP | CDKN2A interacting protein | 0.068 | ||
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.067 | ||
| RNF2 | ring finger protein 2 | 0.067 | ||
| EIF1 | eukaryotic translation initiation factor 1 | 0.067 | ||
| STAG2 | stromal antigen 2 | 0.067 | ||
| CHFR | checkpoint with forkhead and ring finger domains | 0.067 | Mouse | |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.067 | ||
| SOD1 | superoxide dismutase 1, soluble | 0.066 | ||
| UBXN6 | UBX domain protein 6 | 0.066 | ||
| TTK | TTK protein kinase | 0.066 | Yeast | |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.065 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.065 | ||
| RNF166 | ring finger protein 166 | 0.065 | ||
| SESN2 | sestrin 2 | 0.065 | ||
| KLHL13 | kelch-like 13 (Drosophila) | 0.065 | Human | |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.065 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.065 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.065 | ||
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.065 | ||
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.065 | ||
| FAM8A1 | family with sequence similarity 8, member A1 | 0.064 | ||
| RIC8A | resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | 0.064 | ||
| OTUD4 | OTU domain containing 4 | 0.064 | ||
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.064 | ||
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.064 | ||
| RBBP5 | retinoblastoma binding protein 5 | 0.064 | ||
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.064 | ||
| FOXO1 | forkhead box O1 | 0.063 | ||
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.063 | ||
| ATXN1 | ataxin 1 | 0.063 | ||
| SIRT2 | sirtuin 2 | 0.063 | ||
| GTF2B | general transcription factor IIB | 0.063 | ||
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | 0.063 | ||
| RNF181 | ring finger protein 181 | 0.063 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.063 | ||
| UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.063 | Human Yeast Fly | |
| FANCD2 | Fanconi anemia, complementation group D2 | 0.063 | ||
| CDK16 | cyclin-dependent kinase 16 | 0.062 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.062 | ||
| TYRP1 | tyrosinase-related protein 1 | 0.062 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.062 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.062 | ||
| INF2 | inverted formin, FH2 and WH2 domain containing | 0.062 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.062 | ||
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | 0.062 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.062 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.062 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.061 | ||
| GATAD2A | GATA zinc finger domain containing 2A | 0.061 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.061 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.061 | ||
| RNF130 | ring finger protein 130 | 0.061 | ||
| MLF2 | myeloid leukemia factor 2 | 0.061 | ||
| RANBP9 | RAN binding protein 9 | 0.061 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.061 | ||
| FLNB | filamin B, beta | 0.061 | ||
| KLF10 | Kruppel-like factor 10 | 0.061 | ||
| FBXO34 | F-box protein 34 | 0.060 | ||
| NOMO1 | NODAL modulator 1 | 0.060 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.060 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.060 | ||
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 0.060 | ||
| ACVR1 | activin A receptor, type I | 0.060 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.060 | ||
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.060 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.060 | ||
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.060 | ||
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0.060 | ||
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.060 | ||
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.060 | ||
| BARD1 | BRCA1 associated RING domain 1 | 0.060 | ||
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.059 | ||
| SAE1 | SUMO1 activating enzyme subunit 1 | 0.059 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.059 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.059 | ||
| ZNF295 | zinc finger protein 295 | 0.059 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.059 | Human | |
| FEM1B | fem-1 homolog b (C. elegans) | 0.059 | ||
| SLC38A2 | solute carrier family 38, member 2 | 0.059 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.059 | ||
| ZMYND19 | zinc finger, MYND-type containing 19 | 0.059 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.058 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.058 | ||
| KDM2A | lysine (K)-specific demethylase 2A | 0.058 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.058 | ||
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.058 | ||
| RLIM | ring finger protein, LIM domain interacting | 0.058 | ||
| DBP | D site of albumin promoter (albumin D-box) binding protein | 0.057 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.057 | ||
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.057 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.056 | ||
| GORAB | golgin, RAB6-interacting | 0.056 | ||
| CUL7 | cullin 7 | 0.056 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.056 | ||
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 | 0.056 | ||
| FNDC3B | fibronectin type III domain containing 3B | 0.056 | ||
| ATMIN | ATM interactor | 0.056 | ||
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.056 | ||
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.056 | ||
| LONRF1 | LON peptidase N-terminal domain and ring finger 1 | 0.055 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.055 | ||
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.055 | ||
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.055 | ||
| LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.055 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.055 | Mouse | |
| VHL | von Hippel-Lindau tumor suppressor | 0.055 | Mouse | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.055 | ||
| RNF146 | ring finger protein 146 | 0.055 | ||
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.055 | ||
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.055 | ||
| ASF1B | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.054 | ||
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.054 | ||
| NPEPPS | aminopeptidase puromycin sensitive | 0.054 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.054 | ||
| RNF32 | ring finger protein 32 | 0.054 | ||
| EAPP | E2F-associated phosphoprotein | 0.054 | ||
| HDAC3 | histone deacetylase 3 | 0.054 | ||
| DTX2 | deltex homolog 2 (Drosophila) | 0.054 | ||
| RAB14 | RAB14, member RAS oncogene family | 0.054 | ||
| PRKCD | protein kinase C, delta | 0.054 | ||
| RNF8 | ring finger protein 8 | 0.054 | ||
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.054 | ||
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.054 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.054 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.053 | ||
| DDIT4 | DNA-damage-inducible transcript 4 | 0.053 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.053 | ||
| HK2 | hexokinase 2 | 0.053 | ||
| GTF2F1 | general transcription factor IIF, polypeptide 1, 74kDa | 0.053 | ||
| KDM2B | lysine (K)-specific demethylase 2B | 0.053 | ||
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.053 | ||
| UBOX5 | U-box domain containing 5 | 0.053 | ||
| USP38 | ubiquitin specific peptidase 38 | 0.052 | ||
| PIM1 | pim-1 oncogene | 0.052 | ||
| SIL1 | SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae) | 0.052 | ||
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.052 | ||
| RSPRY1 | ring finger and SPRY domain containing 1 | 0.052 | ||
| SMAD6 | SMAD family member 6 | 0.052 | Human | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.052 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.052 | ||
| BIRC8 | baculoviral IAP repeat containing 8 | 0.052 | Human | |
| ELK1 | ELK1, member of ETS oncogene family | 0.052 | ||
| SOX7 | SRY (sex determining region Y)-box 7 | 0.052 | ||
| TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa | 0.052 | ||
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 | 0.052 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.052 | Human | |
| SNX9 | sorting nexin 9 | 0.052 | ||
| TBL1X | transducin (beta)-like 1X-linked | 0.052 | Mouse | |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.051 | ||
| PCM1 | pericentriolar material 1 | 0.051 | ||
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.051 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.051 | ||
| PHF20L1 | PHD finger protein 20-like 1 | 0.051 | ||
| RNF20 | ring finger protein 20 | 0.051 | ||
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.051 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.051 | ||
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.051 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.051 | ||
| ING4 | inhibitor of growth family, member 4 | 0.051 | ||
| GLB1 | galactosidase, beta 1 | 0.050 | ||
| ZFR | zinc finger RNA binding protein | 0.050 | ||
| CCDC50 | coiled-coil domain containing 50 | 0.050 | ||
| NKAP | NFKB activating protein | 0.050 | ||
| PLRG1 | pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) | 0.050 | ||
| MT1A | metallothionein 1A | 0.050 | ||
| FOXK2 | forkhead box K2 | 0.050 | ||
| RYR2 | ryanodine receptor 2 (cardiac) | 0.050 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.050 | ||
| PXN | paxillin | 0.050 | ||
| KDM4A | lysine (K)-specific demethylase 4A | 0.050 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.050 | ||
| WDR48 | WD repeat domain 48 | 0.050 | ||
| TSPYL4 | TSPY-like 4 | 0.050 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.049 | Fly | |
| USP42 | ubiquitin specific peptidase 42 | 0.049 | Human | |
| THAP8 | THAP domain containing 8 | 0.049 | ||
| EMD | emerin | 0.049 | ||
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.049 | ||
| PCGF6 | polycomb group ring finger 6 | 0.049 | ||
| AKIP1 | A kinase (PRKA) interacting protein 1 | 0.049 | ||
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.049 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.049 | Yeast Fly | |
| COMMD6 | COMM domain containing 6 | 0.049 | ||
| COBRA1 | cofactor of BRCA1 | 0.049 | ||
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.049 | ||
| TSC22D4 | TSC22 domain family, member 4 | 0.049 | ||
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.049 | Human | |
| RNF113B | ring finger protein 113B | 0.048 | ||
| DMWD | dystrophia myotonica, WD repeat containing | 0.048 | ||
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase | 0.048 | ||
| SMC3 | structural maintenance of chromosomes 3 | 0.048 | ||
| MBNL2 | muscleblind-like 2 (Drosophila) | 0.048 | ||
| TRIM25 | tripartite motif containing 25 | 0.048 | ||
| WT1 | Wilms tumor 1 | 0.048 | ||
| SFPQ | splicing factor proline/glutamine-rich | 0.048 | ||
| RNF115 | ring finger protein 115 | 0.048 | Human | |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.048 | ||
| PUM1 | pumilio homolog 1 (Drosophila) | 0.048 | ||
| KLHL22 | kelch-like 22 (Drosophila) | 0.048 | ||
| CTSA | cathepsin A | 0.048 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.048 | ||
| BANP | BTG3 associated nuclear protein | 0.048 | ||
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.048 | ||
| DAD1 | defender against cell death 1 | 0.047 | ||
| BAG1 | BCL2-associated athanogene | 0.047 | ||
| TRIM9 | tripartite motif containing 9 | 0.047 | ||
| C1orf124 | chromosome 1 open reading frame 124 | 0.047 | ||
| PRRC1 | proline-rich coiled-coil 1 | 0.047 | ||
| FBXO11 | F-box protein 11 | 0.047 | ||
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 0.047 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.047 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.047 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.047 | ||
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.047 | ||
| ZNF148 | zinc finger protein 148 | 0.047 | ||
| MAPK10 | mitogen-activated protein kinase 10 | 0.047 | ||
| CPD | carboxypeptidase D | 0.047 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.047 | ||
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.046 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.046 | ||
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.046 | ||
| C16orf87 | chromosome 16 open reading frame 87 | 0.046 | ||
| BABAM1 | BRISC and BRCA1 A complex member 1 | 0.046 | ||
| HM13 | histocompatibility (minor) 13 | 0.046 | ||
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.046 | ||
| HIST1H4A | histone cluster 1, H4a | 0.046 | ||
| WAC | WW domain containing adaptor with coiled-coil | 0.046 | ||
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.046 | ||
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.046 | ||
| OSBPL8 | oxysterol binding protein-like 8 | 0.046 | ||
| FBXO44 | F-box protein 44 | 0.046 | Human |