IMP
Process View
extrinsic apoptotic signaling pathway
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "extrinsic apoptotic signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.000 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 1.000 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.000 | ||
| BCL2L1 | BCL2-like 1 | 0.999 | Human Mouse | |
| TRAF2 | TNF receptor-associated factor 2 | 0.998 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.998 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.998 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.997 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.996 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.996 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.995 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.995 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.994 | Human | |
| TRADD | TNFRSF1A-associated via death domain | 0.993 | ||
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.991 | Mouse | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.984 | Human | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.983 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.983 | ||
| FHL2 | four and a half LIM domains 2 | 0.979 | ||
| SMAD2 | SMAD family member 2 | 0.972 | Human | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.953 | Human | |
| BAX | BCL2-associated X protein | 0.953 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.950 | ||
| EGFR | epidermal growth factor receptor | 0.947 | Human | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.938 | Human | |
| RNF11 | ring finger protein 11 | 0.932 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.930 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.927 | Human | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.914 | Human Mouse | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.903 | Human | |
| STK4 | serine/threonine kinase 4 | 0.890 | Mouse | |
| SMAD3 | SMAD family member 3 | 0.885 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.880 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.877 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.871 | ||
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.870 | ||
| AR | androgen receptor | 0.869 | ||
| UBC | ubiquitin C | 0.850 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.840 | Human | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.822 | ||
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.800 | ||
| SQSTM1 | sequestosome 1 | 0.799 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.796 | ||
| PML | promyelocytic leukemia | 0.793 | ||
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.786 | ||
| FLNA | filamin A, alpha | 0.783 | ||
| BAD | BCL2-associated agonist of cell death | 0.783 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.759 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.756 | ||
| TNF | tumor necrosis factor | 0.751 | ||
| SMAD7 | SMAD family member 7 | 0.751 | Human | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.739 | Human | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.734 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.726 | Human | |
| IL4R | interleukin 4 receptor | 0.705 | ||
| BID | BH3 interacting domain death agonist | 0.700 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.696 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.666 | ||
| VEGFA | vascular endothelial growth factor A | 0.665 | Mouse | |
| NRP1 | neuropilin 1 | 0.661 | Mouse | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.657 | Human Mouse | |
| BMP2 | bone morphogenetic protein 2 | 0.654 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.639 | ||
| ENG | endoglin | 0.637 | ||
| HCK | hemopoietic cell kinase | 0.634 | Human | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.630 | Human | |
| IL8 | interleukin 8 | 0.608 | ||
| SMAD4 | SMAD family member 4 | 0.590 | Human | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.586 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.585 | ||
| SMAD1 | SMAD family member 1 | 0.584 | Human | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.584 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.573 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.572 | ||
| FGA | fibrinogen alpha chain | 0.556 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.542 | ||
| TANK | TRAF family member-associated NFKB activator | 0.536 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.534 | ||
| BTRC | beta-transducin repeat containing | 0.532 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.529 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.517 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.504 | Human | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.502 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.499 | ||
| PLAU | plasminogen activator, urokinase | 0.499 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.498 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.496 | Human | |
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.495 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.493 | ||
| APP | amyloid beta (A4) precursor protein | 0.483 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.452 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.449 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.445 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.444 | ||
| FN1 | fibronectin 1 | 0.442 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.441 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.438 | ||
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.435 | ||
| SKIL | SKI-like oncogene | 0.422 | Mouse | |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.421 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.420 | Human | |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.420 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.418 | Human Mouse | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.412 | ||
| FGB | fibrinogen beta chain | 0.401 | ||
| IRF1 | interferon regulatory factor 1 | 0.400 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.396 | ||
| OPTN | optineurin | 0.396 | ||
| PSEN1 | presenilin 1 | 0.391 | ||
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.374 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.368 | ||
| APC | adenomatous polyposis coli | 0.354 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.343 | ||
| RNF31 | ring finger protein 31 | 0.337 | ||
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 0.334 | Human | |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.332 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.332 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.329 | ||
| UBXN7 | UBX domain protein 7 | 0.326 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.326 | ||
| FGG | fibrinogen gamma chain | 0.325 | ||
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.317 | ||
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.313 | ||
| AXIN1 | axin 1 | 0.309 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.307 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.305 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.301 | ||
| BCL2A1 | BCL2-related protein A1 | 0.294 | Human | |
| ICAM1 | intercellular adhesion molecule 1 | 0.287 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.281 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.280 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.276 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.271 | Human Rat | |
| DAXX | death-domain associated protein | 0.269 | ||
| SPRR2A | small proline-rich protein 2A | 0.267 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.262 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.259 | Human | |
| USP15 | ubiquitin specific peptidase 15 | 0.258 | ||
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.257 | Human | |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.257 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.252 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.251 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.249 | Human | |
| ITGB5 | integrin, beta 5 | 0.249 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.248 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.248 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.243 | Human | |
| ANXA1 | annexin A1 | 0.242 | ||
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | 0.240 | ||
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.238 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.232 | Human | |
| SNAPIN | SNAP-associated protein | 0.228 | ||
| SIRT1 | sirtuin 1 | 0.227 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.227 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.226 | ||
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.225 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.222 | Human | |
| MAPK14 | mitogen-activated protein kinase 14 | 0.219 | ||
| THBS1 | thrombospondin 1 | 0.214 | ||
| STK11 | serine/threonine kinase 11 | 0.212 | ||
| KRT8 | keratin 8 | 0.212 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.212 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.211 | ||
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.211 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.210 | ||
| SPHK1 | sphingosine kinase 1 | 0.208 | ||
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.208 | ||
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.208 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.207 | Human | |
| STAT5A | signal transducer and activator of transcription 5A | 0.206 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.204 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.199 | ||
| CD63 | CD63 molecule | 0.198 | ||
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.194 | ||
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.194 | Human | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.191 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.190 | ||
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.189 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.189 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.188 | ||
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.185 | ||
| SMAD5 | SMAD family member 5 | 0.180 | Human | |
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.179 | ||
| SNX9 | sorting nexin 9 | 0.178 | ||
| UROD | uroporphyrinogen decarboxylase | 0.176 | ||
| RLN3 | relaxin 3 | 0.175 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.174 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.173 | Human | |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.172 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.171 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.171 | Human | |
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.168 | Human | |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.165 | Mouse | |
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.163 | ||
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.163 | Human Mouse | |
| ACVR1 | activin A receptor, type I | 0.163 | ||
| PXN | paxillin | 0.161 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.159 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.159 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.156 | ||
| STK3 | serine/threonine kinase 3 | 0.156 | Mouse | |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.155 | ||
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.155 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.149 | ||
| SYK | spleen tyrosine kinase | 0.148 | ||
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.147 | ||
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.147 | ||
| PRKCA | protein kinase C, alpha | 0.147 | ||
| MUTED | muted homolog (mouse) | 0.146 | ||
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.145 | ||
| PLAT | plasminogen activator, tissue | 0.144 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.144 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.143 | ||
| SOD1 | superoxide dismutase 1, soluble | 0.141 | ||
| SESN2 | sestrin 2 | 0.141 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.140 | ||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.140 | Rat | |
| IRF7 | interferon regulatory factor 7 | 0.140 | ||
| ITGA6 | integrin, alpha 6 | 0.140 | ||
| ITGB1BP1 | integrin beta 1 binding protein 1 | 0.139 | ||
| FOXO1 | forkhead box O1 | 0.138 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.137 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.136 | ||
| ING2 | inhibitor of growth family, member 2 | 0.135 | ||
| BAK1 | BCL2-antagonist/killer 1 | 0.133 | Human | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.132 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.131 | Human | |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.129 | ||
| TBK1 | TANK-binding kinase 1 | 0.128 | ||
| INHBA | inhibin, beta A | 0.127 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.127 | Human | |
| BBC3 | BCL2 binding component 3 | 0.126 | ||
| YAP1 | Yes-associated protein 1 | 0.125 | Mouse | |
| SP100 | SP100 nuclear antigen | 0.123 | ||
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.123 | ||
| SH3RF3 | SH3 domain containing ring finger 3 | 0.120 | Human | |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.120 | ||
| SH2D1A | SH2 domain containing 1A | 0.120 | ||
| FAM101B | family with sequence similarity 101, member B | 0.119 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.117 | ||
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.117 | ||
| PF4 | platelet factor 4 | 0.117 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.117 | ||
| IL1R2 | interleukin 1 receptor, type II | 0.115 | ||
| LIMD1 | LIM domains containing 1 | 0.115 | ||
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.115 | ||
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.114 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.114 | ||
| STBD1 | starch binding domain 1 | 0.113 | ||
| SIAH2 | seven in absentia homolog 2 (Drosophila) | 0.113 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.112 | ||
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.111 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.110 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.107 | ||
| CRYAB | crystallin, alpha B | 0.107 | ||
| MICA | MHC class I polypeptide-related sequence A | 0.106 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.106 | ||
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.106 | Mouse | |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.106 | ||
| ITK | IL2-inducible T-cell kinase | 0.106 | ||
| RUNX1 | runt-related transcription factor 1 | 0.106 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.103 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.102 | ||
| VAMP3 | vesicle-associated membrane protein 3 (cellubrevin) | 0.102 | ||
| FST | follistatin | 0.102 | ||
| MAPK7 | mitogen-activated protein kinase 7 | 0.099 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.098 | ||
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 0.097 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.096 | ||
| EPHA2 | EPH receptor A2 | 0.096 | ||
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.093 | ||
| IL7R | interleukin 7 receptor | 0.093 | ||
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.093 | ||
| ANXA2 | annexin A2 | 0.093 | ||
| PCNA | proliferating cell nuclear antigen | 0.092 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.092 | ||
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.092 | ||
| CCR2 | chemokine (C-C motif) receptor 2 | 0.092 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.091 | ||
| TLN1 | talin 1 | 0.091 | ||
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.090 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.090 | ||
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.090 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.089 | Human | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.089 | ||
| TNC | tenascin C | 0.088 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.088 | ||
| TUBB6 | tubulin, beta 6 | 0.088 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.087 | Human | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.087 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.087 | ||
| OSMR | oncostatin M receptor | 0.086 | ||
| TP73 | tumor protein p73 | 0.086 | ||
| IL1A | interleukin 1, alpha | 0.086 | Human Mouse | |
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.086 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.085 | Mouse | |
| ZFX | zinc finger protein, X-linked | 0.084 | ||
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.084 | ||
| ITGB4 | integrin, beta 4 | 0.084 | ||
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.082 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.082 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.082 | ||
| MAPK3 | mitogen-activated protein kinase 3 | 0.081 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.081 | ||
| JUP | junction plakoglobin | 0.081 | ||
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.081 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.080 | ||
| GDF5 | growth differentiation factor 5 | 0.079 | ||
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.079 | ||
| LDLR | low density lipoprotein receptor | 0.079 | ||
| FLNB | filamin B, beta | 0.079 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.079 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.079 | Mouse | |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.078 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.078 | ||
| NRP2 | neuropilin 2 | 0.078 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.078 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.078 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.078 | ||
| PLEK | pleckstrin | 0.077 | ||
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.077 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.077 | ||
| PTEN | phosphatase and tensin homolog | 0.077 | ||
| TMSB10 | thymosin beta 10 | 0.077 | ||
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.077 | ||
| CSF1 | colony stimulating factor 1 (macrophage) | 0.076 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.076 | Human | |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.076 | Human | |
| GAS7 | growth arrest-specific 7 | 0.076 | ||
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.076 | ||
| CSF3 | colony stimulating factor 3 (granulocyte) | 0.075 | ||
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.075 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.075 | ||
| MYO6 | myosin VI | 0.075 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.074 | ||
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.074 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.074 | Human | |
| CRP | C-reactive protein, pentraxin-related | 0.073 | ||
| ZFYVE1 | zinc finger, FYVE domain containing 1 | 0.073 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.073 | ||
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.073 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.073 | ||
| TBX5 | T-box 5 | 0.073 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.073 | ||
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.072 | ||
| HDAC6 | histone deacetylase 6 | 0.072 | ||
| CA12 | carbonic anhydrase XII | 0.071 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.070 | ||
| CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 0.070 | ||
| NRG1 | neuregulin 1 | 0.070 | ||
| ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.070 | ||
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.069 | ||
| SMAD6 | SMAD family member 6 | 0.069 | Human | |
| SLC38A2 | solute carrier family 38, member 2 | 0.069 | ||
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.069 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.068 | ||
| PVR | poliovirus receptor | 0.068 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.068 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.068 | ||
| IRF4 | interferon regulatory factor 4 | 0.068 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.068 | Mouse | |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.068 | ||
| BAG1 | BCL2-associated athanogene | 0.067 | ||
| NOTCH1 | notch 1 | 0.067 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.067 | ||
| RXRA | retinoid X receptor, alpha | 0.067 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.067 | ||
| IL1B | interleukin 1, beta | 0.066 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.065 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.064 | ||
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.064 | ||
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.064 | ||
| S100A10 | S100 calcium binding protein A10 | 0.064 | ||
| ZC3HC1 | zinc finger, C3HC-type containing 1 | 0.064 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.063 | ||
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.063 | ||
| MEFV | Mediterranean fever | 0.063 | ||
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.063 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.063 | ||
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.063 | ||
| RIOK3 | RIO kinase 3 (yeast) | 0.063 | ||
| ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.063 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.063 | ||
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.062 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.062 | ||
| LAMB3 | laminin, beta 3 | 0.062 | ||
| SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.061 | ||
| DLG3 | discs, large homolog 3 (Drosophila) | 0.061 | ||
| CLU | clusterin | 0.061 | ||
| STC1 | stanniocalcin 1 | 0.061 | ||
| CHN2 | chimerin (chimaerin) 2 | 0.061 | ||
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.061 | Human | |
| TRIM21 | tripartite motif containing 21 | 0.061 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.061 | ||
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.060 | ||
| ARHGAP5 | Rho GTPase activating protein 5 | 0.060 | ||
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.059 | ||
| TUBA1A | tubulin, alpha 1a | 0.059 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.059 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.059 | ||
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.059 | ||
| FOSL1 | FOS-like antigen 1 | 0.059 | ||
| PDGFC | platelet derived growth factor C | 0.058 | ||
| FGF2 | fibroblast growth factor 2 (basic) | 0.058 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.058 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.058 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.058 | Human | |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.058 | ||
| TIFA | TRAF-interacting protein with forkhead-associated domain | 0.058 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.057 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.057 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.057 | Human | |
| PGF | placental growth factor | 0.057 | ||
| IL11 | interleukin 11 | 0.056 | ||
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.056 | Human | |
| RNF4 | ring finger protein 4 | 0.056 | ||
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.056 | ||
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.056 | Human | |
| CD44 | CD44 molecule (Indian blood group) | 0.056 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.056 | Human | |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.056 | ||
| TP53 | tumor protein p53 | 0.056 | ||
| SRI | sorcin | 0.056 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.056 | ||
| IER3 | immediate early response 3 | 0.055 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.055 | ||
| UPP1 | uridine phosphorylase 1 | 0.055 | ||
| BCL2L2 | BCL2-like 2 | 0.055 | Human | |
| FHL3 | four and a half LIM domains 3 | 0.055 | ||
| ATF2 | activating transcription factor 2 | 0.055 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.055 | ||
| FGF7 | fibroblast growth factor 7 | 0.054 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.054 | ||
| NGFR | nerve growth factor receptor | 0.054 | ||
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.054 | ||
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.054 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.054 | ||
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.054 | ||
| IFNG | interferon, gamma | 0.054 | ||
| ITGB7 | integrin, beta 7 | 0.053 | ||
| PTK6 | PTK6 protein tyrosine kinase 6 | 0.053 | Human | |
| KLF13 | Kruppel-like factor 13 | 0.053 | ||
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.052 | Human | |
| PRDX1 | peroxiredoxin 1 | 0.052 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.052 | Human | |
| IL2RB | interleukin 2 receptor, beta | 0.052 | ||
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.052 | ||
| TRO | trophinin | 0.051 | ||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.051 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.051 | Human | |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.051 | ||
| LAMC2 | laminin, gamma 2 | 0.051 | ||
| BANP | BTG3 associated nuclear protein | 0.051 | ||
| HBB | hemoglobin, beta | 0.051 | ||
| FGF10 | fibroblast growth factor 10 | 0.051 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.051 | ||
| VDAC1 | voltage-dependent anion channel 1 | 0.051 | ||
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.050 | ||
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.050 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.050 | ||
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.050 | ||
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.050 | ||
| RGS4 | regulator of G-protein signaling 4 | 0.050 | ||
| BLNK | B-cell linker | 0.050 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.050 | Human | |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.050 | ||
| TFPI2 | tissue factor pathway inhibitor 2 | 0.050 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.049 | ||
| BDNF | brain-derived neurotrophic factor | 0.049 | Human | |
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.049 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.049 | ||
| PI3 | peptidase inhibitor 3, skin-derived | 0.049 | ||
| EFNA1 | ephrin-A1 | 0.049 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.049 | ||
| SORT1 | sortilin 1 | 0.048 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.048 | ||
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.048 | ||
| F2 | coagulation factor II (thrombin) | 0.048 | ||
| DARC | Duffy blood group, chemokine receptor | 0.047 | ||
| VTN | vitronectin | 0.047 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.047 | ||
| PTRF | polymerase I and transcript release factor | 0.047 | ||
| CD83 | CD83 molecule | 0.047 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.046 | ||
| CD9 | CD9 molecule | 0.046 | ||
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.046 | ||
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.045 | ||
| KIAA1267 | KIAA1267 | 0.045 | ||
| PF4V1 | platelet factor 4 variant 1 | 0.045 | Human | |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.045 | Human | |
| CTGF | connective tissue growth factor | 0.045 | ||
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.045 | ||
| TSPO | translocator protein (18kDa) | 0.045 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.045 | ||
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.045 | ||
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.044 | ||
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 0.044 | ||
| S100A6 | S100 calcium binding protein A6 | 0.044 | ||
| NPC2 | Niemann-Pick disease, type C2 | 0.044 | ||
| RARA | retinoic acid receptor, alpha | 0.044 | ||
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.044 | ||
| SH2D2A | SH2 domain containing 2A | 0.044 | ||
| IL13 | interleukin 13 | 0.044 | ||
| MXD1 | MAX dimerization protein 1 | 0.044 | ||
| SELE | selectin E | 0.044 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.044 | ||
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.044 | ||
| JAK3 | Janus kinase 3 | 0.043 | Mouse | |
| EREG | epiregulin | 0.043 | ||
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.043 | ||
| ACVRL1 | activin A receptor type II-like 1 | 0.043 | Human | |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 0.043 | ||
| AHNAK | AHNAK nucleoprotein | 0.043 | ||
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.043 | ||
| ULK1 | unc-51-like kinase 1 (C. elegans) | 0.042 | ||
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.042 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.042 | ||
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.042 | ||
| WNT2 | wingless-type MMTV integration site family member 2 | 0.042 | ||
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.042 | ||
| MSC | musculin | 0.041 | ||
| HMHA1 | histocompatibility (minor) HA-1 | 0.041 | ||
| AZI2 | 5-azacytidine induced 2 | 0.041 | ||
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.041 | ||
| FGFR3 | fibroblast growth factor receptor 3 | 0.041 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.041 | ||
| AXL | AXL receptor tyrosine kinase | 0.041 | ||
| FSTL1 | follistatin-like 1 | 0.041 | ||
| ORM1 | orosomucoid 1 | 0.041 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.041 | ||
| CD48 | CD48 molecule | 0.041 | ||
| MEF2A | myocyte enhancer factor 2A | 0.041 | ||
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.041 | ||
| THBD | thrombomodulin | 0.041 | ||
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.041 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.041 | Human | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.040 | ||
| CD80 | CD80 molecule | 0.040 | ||
| DUSP9 | dual specificity phosphatase 9 | 0.040 | ||
| NTF3 | neurotrophin 3 | 0.040 | Human | |
| AHR | aryl hydrocarbon receptor | 0.040 | ||
| HIST2H3C | histone cluster 2, H3c | 0.040 | ||
| PRNP | prion protein | 0.040 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.040 | ||
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.040 | ||
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.040 | Human | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.040 | ||
| IL15RA | interleukin 15 receptor, alpha | 0.040 | ||
| TLR2 | toll-like receptor 2 | 0.040 | ||
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.039 | ||
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.039 | ||
| LOXL2 | lysyl oxidase-like 2 | 0.039 | ||
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.039 | ||
| RUNX3 | runt-related transcription factor 3 | 0.039 | Mouse | |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.039 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.039 | ||
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.039 | ||
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.039 | Human | |
| AQP9 | aquaporin 9 | 0.039 | ||
| EP300 | E1A binding protein p300 | 0.039 | ||
| LRP3 | low density lipoprotein receptor-related protein 3 | 0.039 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.039 | ||
| TENC1 | tensin like C1 domain containing phosphatase (tensin 2) | 0.039 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.039 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.039 | ||
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.039 | ||
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.039 | ||
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.039 | ||
| NCK1 | NCK adaptor protein 1 | 0.038 | ||
| SMG6 | Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) | 0.038 | ||
| TEK | TEK tyrosine kinase, endothelial | 0.038 | ||
| ATG16L1 | ATG16 autophagy related 16-like 1 (S. cerevisiae) | 0.038 | ||
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 0.038 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.038 | ||
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.038 | ||
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.038 | ||
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.038 | ||
| WDR26 | WD repeat domain 26 | 0.038 | ||
| STK17A | serine/threonine kinase 17a | 0.038 | ||
| HIC1 | hypermethylated in cancer 1 | 0.037 | ||
| INSR | insulin receptor | 0.037 | ||
| LIMK2 | LIM domain kinase 2 | 0.037 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.037 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.037 | ||
| HRK | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.037 | ||
| MAGEH1 | melanoma antigen family H, 1 | 0.037 | ||
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.037 | ||
| DLG2 | discs, large homolog 2 (Drosophila) | 0.037 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.037 | ||
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.036 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.036 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.036 | ||
| JAG1 | jagged 1 | 0.036 | ||
| ANXA5 | annexin A5 | 0.036 | ||
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.036 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.036 | ||
| MEF2C | myocyte enhancer factor 2C | 0.036 | ||
| UBD | ubiquitin D | 0.036 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.036 | Mouse | |
| FTL | ferritin, light polypeptide | 0.036 | ||
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.036 | ||
| IL2RA | interleukin 2 receptor, alpha | 0.036 | ||
| ATM | ataxia telangiectasia mutated | 0.036 | ||
| MAPK11 | mitogen-activated protein kinase 11 | 0.036 | ||
| GPR109B | G protein-coupled receptor 109B | 0.036 | ||
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.036 | ||
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.036 | ||
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.036 | ||
| PTHLH | parathyroid hormone-like hormone | 0.036 | ||
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.036 | ||
| NUMBL | numb homolog (Drosophila)-like | 0.036 | ||
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.035 | ||
| NOV | nephroblastoma overexpressed gene | 0.035 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.035 | ||
| TRIM8 | tripartite motif containing 8 | 0.035 | ||
| CD320 | CD320 molecule | 0.035 | ||
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.035 | ||
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.035 | ||
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.035 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.035 | ||
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 0.035 | ||
| VEGFC | vascular endothelial growth factor C | 0.035 | ||
| CD36 | CD36 molecule (thrombospondin receptor) | 0.035 | ||
| TNIK | TRAF2 and NCK interacting kinase | 0.035 | ||
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.035 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.035 | ||
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.035 | ||
| FTH1 | ferritin, heavy polypeptide 1 | 0.034 | ||
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 0.034 | ||
| FGFR2 | fibroblast growth factor receptor 2 | 0.034 | Human | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.034 | ||
| CCL1 | chemokine (C-C motif) ligand 1 | 0.034 | ||
| EMD | emerin | 0.034 | ||
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.034 | ||
| CSF1R | colony stimulating factor 1 receptor | 0.034 | ||
| STX5 | syntaxin 5 | 0.034 | ||
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.034 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.034 | ||
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.034 | ||
| TRIM33 | tripartite motif containing 33 | 0.034 | ||
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.034 | ||
| TGFB2 | transforming growth factor, beta 2 | 0.034 | ||
| S100A12 | S100 calcium binding protein A12 | 0.034 | ||
| CD7 | CD7 molecule | 0.034 | ||
| CD163 | CD163 molecule | 0.034 | ||
| POU2F2 | POU class 2 homeobox 2 | 0.034 | ||
| GPX4 | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 0.034 | ||
| ANXA4 | annexin A4 | 0.034 | ||
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.033 | ||
| IRF3 | interferon regulatory factor 3 | 0.033 | ||
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.033 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.033 | ||
| ADAM9 | ADAM metallopeptidase domain 9 | 0.033 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.033 | ||
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.033 | Human | |
| NINJ1 | ninjurin 1 | 0.033 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.033 | ||
| F2R | coagulation factor II (thrombin) receptor | 0.033 | ||
| COL16A1 | collagen, type XVI, alpha 1 | 0.033 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.033 | ||
| RHEB | Ras homolog enriched in brain | 0.033 | ||
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.033 | ||
| HBA2 | hemoglobin, alpha 2 | 0.033 | ||
| ACVR2B | activin A receptor, type IIB | 0.033 | ||
| CAV2 | caveolin 2 | 0.033 | Human | |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.033 | ||
| GDF15 | growth differentiation factor 15 | 0.033 | ||
| ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.033 | ||
| EMP1 | epithelial membrane protein 1 | 0.033 | ||
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 | 0.033 | ||
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.032 | ||
| CD27 | CD27 molecule | 0.032 | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.032 | Mouse | |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.032 | ||
| MEOX2 | mesenchyme homeobox 2 | 0.032 | ||
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.032 | ||
| ZNF451 | zinc finger protein 451 | 0.032 | ||
| VIM | vimentin | 0.032 | ||
| S100A11 | S100 calcium binding protein A11 | 0.032 | ||
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.032 | Human | |
| RGS14 | regulator of G-protein signaling 14 | 0.032 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.032 | ||
| CCPG1 | cell cycle progression 1 | 0.032 | ||
| BAG2 | BCL2-associated athanogene 2 | 0.032 | ||
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.032 | ||
| S100A3 | S100 calcium binding protein A3 | 0.032 | ||
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.032 | ||
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.032 | ||
| ASRGL1 | asparaginase like 1 | 0.032 | ||
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.032 | ||
| S100A4 | S100 calcium binding protein A4 | 0.032 | ||
| WBP5 | WW domain binding protein 5 | 0.032 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.032 | Mouse | |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.032 | ||
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.032 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.032 | ||
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.032 | ||
| MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 0.032 | ||
| RIN1 | Ras and Rab interactor 1 | 0.032 | ||
| DST | dystonin | 0.031 | ||
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | 0.031 | ||
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.031 | ||
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.031 | ||
| LRDD | leucine-rich repeats and death domain containing | 0.031 | Mouse | |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.031 | ||
| IFI44 | interferon-induced protein 44 | 0.031 | ||
| ATG7 | ATG7 autophagy related 7 homolog (S. cerevisiae) | 0.031 | ||
| IL32 | interleukin 32 | 0.031 | ||
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.031 | ||
| BDKRB2 | bradykinin receptor B2 | 0.031 | Human | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.031 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.031 | ||
| DTX1 | deltex homolog 1 (Drosophila) | 0.031 | ||
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.031 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.031 | ||
| FCHO2 | FCH domain only 2 | 0.031 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.031 | ||
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.030 | ||
| ROBO4 | roundabout homolog 4, magic roundabout (Drosophila) | 0.030 | ||
| IRF8 | interferon regulatory factor 8 | 0.030 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.030 | ||
| ATG2A | ATG2 autophagy related 2 homolog A (S. cerevisiae) | 0.030 | ||
| CHGB | chromogranin B (secretogranin 1) | 0.030 | ||
| SFRP2 | secreted frizzled-related protein 2 | 0.030 | Human Mouse | |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.030 | ||
| MTMR4 | myotubularin related protein 4 | 0.030 | ||
| ATXN3 | ataxin 3 | 0.030 | ||
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.030 | ||
| CALR | calreticulin | 0.030 | ||
| SPP1 | secreted phosphoprotein 1 | 0.029 | ||
| SH2B3 | SH2B adaptor protein 3 | 0.029 | ||
| KYNU | kynureninase | 0.029 | ||
| C4orf14 | chromosome 4 open reading frame 14 | 0.029 | ||
| IFIH1 | interferon induced with helicase C domain 1 | 0.029 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.029 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.029 | ||
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.029 | Mouse | |
| GREM1 | gremlin 1 | 0.029 | ||
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.029 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.029 | Human | |
| MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 0.029 | ||
| CCND1 | cyclin D1 | 0.029 | ||
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.029 | ||
| SOCS5 | suppressor of cytokine signaling 5 | 0.029 | ||
| RFC1 | replication factor C (activator 1) 1, 145kDa | 0.029 | ||
| DHH | desert hedgehog | 0.029 | ||
| SFRP4 | secreted frizzled-related protein 4 | 0.029 | ||
| SELL | selectin L | 0.029 | ||
| PRDX4 | peroxiredoxin 4 | 0.029 | ||
| DOK2 | docking protein 2, 56kDa | 0.029 |