IMP
Process View
proteolysis involved in cellular protein catabolic process
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
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Click on a gene's description to view its network relationships with genes known to be involved in "proteolysis involved in cellular protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| UBC | ubiquitin C | 1.000 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 1.000 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 1.000 | Human Yeast | |
| XIAP | X-linked inhibitor of apoptosis | 1.000 | Human | |
| RNF11 | ring finger protein 11 | 1.000 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 1.000 | ||
| TP53 | tumor protein p53 | 1.000 | ||
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 1.000 | ||
| VCP | valosin containing protein | 0.999 | ||
| UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.999 | Mouse | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.998 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.998 | Yeast Worm | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.998 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.997 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.996 | ||
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.996 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.993 | Mouse Fly | |
| RB1 | retinoblastoma 1 | 0.993 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.993 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.992 | ||
| BTRC | beta-transducin repeat containing | 0.991 | ||
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.991 | Yeast Mouse | |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.991 | Yeast | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.989 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.988 | ||
| ATXN3 | ataxin 3 | 0.987 | Mouse | |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.987 | ||
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.985 | Yeast | |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.984 | ||
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.983 | Yeast | |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.982 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.980 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.978 | ||
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.977 | Yeast | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.977 | Human Mouse | |
| CCNB1 | cyclin B1 | 0.975 | ||
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.974 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.974 | ||
| CUL3 | cullin 3 | 0.973 | ||
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.972 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.971 | ||
| SMAD4 | SMAD family member 4 | 0.970 | Human | |
| RNF111 | ring finger protein 111 | 0.970 | Mouse | |
| UBQLN1 | ubiquilin 1 | 0.969 | Human | |
| TRIM39 | tripartite motif containing 39 | 0.967 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.967 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.965 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.964 | ||
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.961 | Yeast | |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.955 | Yeast | |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.954 | Yeast | |
| SQSTM1 | sequestosome 1 | 0.951 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.950 | ||
| UBE3A | ubiquitin protein ligase E3A | 0.950 | Mouse Fly | |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.948 | Zebrafish | |
| SMAD2 | SMAD family member 2 | 0.948 | Human | |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.946 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.944 | ||
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.941 | ||
| POMP | proteasome maturation protein | 0.941 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.933 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.932 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.929 | ||
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.928 | Yeast | |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.924 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.923 | ||
| CCNA2 | cyclin A2 | 0.918 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.916 | ||
| RNF126 | ring finger protein 126 | 0.912 | ||
| RNF5 | ring finger protein 5 | 0.908 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.902 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.900 | Human | |
| ZNRF1 | zinc and ring finger 1 | 0.893 | Mouse | |
| CUL1 | cullin 1 | 0.893 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.892 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.891 | Fly | |
| ANAPC7 | anaphase promoting complex subunit 7 | 0.889 | ||
| PLK1 | polo-like kinase 1 | 0.889 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.880 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.873 | Yeast | |
| MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.868 | ||
| FAF2 | Fas associated factor family member 2 | 0.865 | ||
| CUL2 | cullin 2 | 0.864 | Worm | |
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.863 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.861 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.861 | Mouse Fly | |
| HSPA8 | heat shock 70kDa protein 8 | 0.852 | ||
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.851 | Yeast | |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.845 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.837 | Human | |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.828 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.825 | ||
| FBXO5 | F-box protein 5 | 0.823 | ||
| UBXN7 | UBX domain protein 7 | 0.820 | Yeast | |
| UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.813 | Yeast Mouse | |
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.810 | Mouse | |
| DERL1 | Der1-like domain family, member 1 | 0.805 | ||
| PJA2 | praja ring finger 2 | 0.798 | ||
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.798 | ||
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.793 | Yeast | |
| AMFR | autocrine motility factor receptor | 0.792 | ||
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.791 | Yeast | |
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.791 | Yeast Fly | |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.779 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.777 | Yeast | |
| HSPA4 | heat shock 70kDa protein 4 | 0.775 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.775 | ||
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.771 | Worm Fly | |
| HDAC2 | histone deacetylase 2 | 0.770 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.757 | Yeast | |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.757 | Yeast | |
| NCF1 | neutrophil cytosolic factor 1 | 0.754 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.742 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.742 | ||
| SMAD5 | SMAD family member 5 | 0.734 | Human | |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.728 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.727 | ||
| EP300 | E1A binding protein p300 | 0.727 | ||
| HDAC1 | histone deacetylase 1 | 0.726 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.725 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.721 | ||
| CSNK1E | casein kinase 1, epsilon | 0.717 | Mouse Fly | |
| RNF168 | ring finger protein 168 | 0.716 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.714 | ||
| BRCA1 | breast cancer 1, early onset | 0.711 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.710 | Human | |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.707 | Mouse | |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.706 | Yeast | |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.696 | Human | |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.696 | Yeast | |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.692 | Yeast | |
| YY1 | YY1 transcription factor | 0.689 | ||
| SELS | selenoprotein S | 0.680 | ||
| TSG101 | tumor susceptibility gene 101 | 0.675 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.674 | ||
| RNF14 | ring finger protein 14 | 0.665 | ||
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.654 | Yeast | |
| ANAPC1 | anaphase promoting complex subunit 1 | 0.654 | Worm Fly | |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.648 | Yeast | |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.646 | ||
| TRIM43 | tripartite motif containing 43 | 0.635 | ||
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.631 | Yeast | |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.629 | Human | |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.628 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.627 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.627 | ||
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.625 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.624 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.622 | ||
| SNX9 | sorting nexin 9 | 0.619 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.619 | Human | |
| KLHL12 | kelch-like 12 (Drosophila) | 0.618 | Human | |
| AXIN1 | axin 1 | 0.616 | Mouse Rat | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.616 | ||
| FBXW2 | F-box and WD repeat domain containing 2 | 0.610 | ||
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.608 | ||
| FBXO7 | F-box protein 7 | 0.599 | ||
| HSPA1A | heat shock 70kDa protein 1A | 0.599 | Yeast | |
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.597 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.592 | Fly | |
| DAXX | death-domain associated protein | 0.588 | ||
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.583 | Yeast | |
| ATXN1 | ataxin 1 | 0.582 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.570 | ||
| SMAD3 | SMAD family member 3 | 0.567 | Human | |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.567 | Human Yeast | |
| KDM1A | lysine (K)-specific demethylase 1A | 0.564 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.558 | ||
| RNF2 | ring finger protein 2 | 0.554 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.553 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.550 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.547 | Human | |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.547 | ||
| TRIM27 | tripartite motif containing 27 | 0.541 | Human | |
| PSAP | prosaposin | 0.541 | ||
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.540 | Yeast | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.536 | ||
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.532 | ||
| SMAD7 | SMAD family member 7 | 0.531 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.529 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.529 | ||
| UBXN1 | UBX domain protein 1 | 0.527 | ||
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.522 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.518 | ||
| USP15 | ubiquitin specific peptidase 15 | 0.517 | Human | |
| NCF2 | neutrophil cytosolic factor 2 | 0.514 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.510 | ||
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.510 | ||
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.510 | Worm | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.506 | Human Yeast | |
| TRIM8 | tripartite motif containing 8 | 0.505 | Yeast | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.505 | Rat | |
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.505 | ||
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.505 | ||
| PRKCA | protein kinase C, alpha | 0.501 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.496 | ||
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.493 | ||
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.492 | ||
| MIB1 | mindbomb homolog 1 (Drosophila) | 0.486 | ||
| AR | androgen receptor | 0.479 | ||
| CCNE1 | cyclin E1 | 0.477 | Fly | |
| TADA3 | transcriptional adaptor 3 | 0.475 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.475 | Mouse | |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.471 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.470 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.465 | Fly | |
| PML | promyelocytic leukemia | 0.464 | ||
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.456 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.443 | Human | |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.442 | Fly | |
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.441 | ||
| UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.440 | Human Yeast Fly | |
| MKRN1 | makorin ring finger protein 1 | 0.432 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.430 | ||
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.422 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.419 | Human | |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.417 | ||
| CHFR | checkpoint with forkhead and ring finger domains | 0.414 | ||
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.410 | Mouse | |
| RNF7 | ring finger protein 7 | 0.409 | ||
| MBD3 | methyl-CpG binding domain protein 3 | 0.404 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.401 | ||
| SUMO3 | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) | 0.387 | Human Mouse | |
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.385 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.376 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.370 | Human | |
| SSR1 | signal sequence receptor, alpha | 0.369 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.366 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.365 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.363 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.363 | ||
| PPP5C | protein phosphatase 5, catalytic subunit | 0.360 | ||
| WAC | WW domain containing adaptor with coiled-coil | 0.357 | ||
| GABARAP | GABA(A) receptor-associated protein | 0.354 | ||
| SMAD1 | SMAD family member 1 | 0.353 | Human | |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.352 | ||
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.348 | Human | |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.347 | Mouse | |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.347 | ||
| KIF5B | kinesin family member 5B | 0.346 | ||
| RANBP9 | RAN binding protein 9 | 0.346 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.341 | ||
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.339 | ||
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.334 | ||
| SMC6 | structural maintenance of chromosomes 6 | 0.332 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.332 | ||
| ACTB | actin, beta | 0.327 | ||
| CCND1 | cyclin D1 | 0.325 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.321 | Mouse | |
| IRF1 | interferon regulatory factor 1 | 0.320 | ||
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.320 | ||
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.317 | ||
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.317 | Human | |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.316 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.315 | ||
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.315 | Yeast | |
| CEP55 | centrosomal protein 55kDa | 0.315 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.314 | ||
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.314 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.311 | Yeast | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.310 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.310 | ||
| HERC2 | hect domain and RLD 2 | 0.309 | ||
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.309 | ||
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.308 | Mouse | |
| KEAP1 | kelch-like ECH-associated protein 1 | 0.307 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.304 | ||
| RNF20 | ring finger protein 20 | 0.302 | ||
| BAG1 | BCL2-associated athanogene | 0.302 | ||
| NBR1 | neighbor of BRCA1 gene 1 | 0.299 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.299 | Human | |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.298 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.297 | ||
| HDAC6 | histone deacetylase 6 | 0.296 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.296 | ||
| EPOR | erythropoietin receptor | 0.293 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.291 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.289 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.287 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.287 | Human | |
| ATN1 | atrophin 1 | 0.285 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.284 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.284 | ||
| SP110 | SP110 nuclear body protein | 0.284 | ||
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.283 | Human | |
| VHL | von Hippel-Lindau tumor suppressor | 0.281 | Mouse | |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.281 | Fly | |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.281 | ||
| TRIM21 | tripartite motif containing 21 | 0.280 | Human | |
| CREBBP | CREB binding protein | 0.277 | ||
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.276 | ||
| NBN | nibrin | 0.276 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.276 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.276 | Human | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.274 | Human | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.274 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.272 | Yeast | |
| KCTD10 | potassium channel tetramerisation domain containing 10 | 0.272 | Human | |
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.272 | Yeast Mouse | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.271 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.270 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.268 | ||
| DZIP3 | DAZ interacting protein 3, zinc finger | 0.268 | Human | |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.267 | ||
| TFDP1 | transcription factor Dp-1 | 0.267 | ||
| TRIM5 | tripartite motif containing 5 | 0.266 | Human | |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.261 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.259 | ||
| RYBP | RING1 and YY1 binding protein | 0.257 | Fly | |
| RNF4 | ring finger protein 4 | 0.255 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.255 | Mouse | |
| ANKRD17 | ankyrin repeat domain 17 | 0.253 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.251 | ||
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.250 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.248 | ||
| RNF114 | ring finger protein 114 | 0.248 | ||
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.247 | Worm | |
| NMI | N-myc (and STAT) interactor | 0.245 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.245 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.242 | ||
| RNF38 | ring finger protein 38 | 0.242 | ||
| CUL5 | cullin 5 | 0.241 | ||
| ANAPC16 | anaphase promoting complex subunit 16 | 0.241 | ||
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.241 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.240 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.239 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.238 | ||
| RNF26 | ring finger protein 26 | 0.236 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.234 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.233 | ||
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.231 | Yeast | |
| TRIM28 | tripartite motif containing 28 | 0.230 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.229 | ||
| CARM1 | coactivator-associated arginine methyltransferase 1 | 0.228 | ||
| ERBB2IP | erbb2 interacting protein | 0.227 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.225 | ||
| E2F1 | E2F transcription factor 1 | 0.225 | ||
| FHL2 | four and a half LIM domains 2 | 0.224 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.224 | ||
| GLI1 | GLI family zinc finger 1 | 0.223 | ||
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.223 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.223 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.223 | ||
| TRIM23 | tripartite motif containing 23 | 0.220 | ||
| VTA1 | Vps20-associated 1 homolog (S. cerevisiae) | 0.219 | ||
| BAG2 | BCL2-associated athanogene 2 | 0.214 | ||
| H2AFX | H2A histone family, member X | 0.213 | ||
| ZNF496 | zinc finger protein 496 | 0.212 | ||
| SEC24B | SEC24 family, member B (S. cerevisiae) | 0.210 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.210 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.209 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.207 | ||
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.205 | ||
| AURKB | aurora kinase B | 0.204 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.202 | ||
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.201 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.200 | ||
| CUL4A | cullin 4A | 0.199 | Mouse | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.198 | ||
| ESR1 | estrogen receptor 1 | 0.197 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.197 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.197 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.196 | ||
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.195 | ||
| RNF10 | ring finger protein 10 | 0.194 | ||
| BAG6 | BCL2-associated athanogene 6 | 0.194 | Mouse | |
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.193 | ||
| YAP1 | Yes-associated protein 1 | 0.192 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.192 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.192 | Rat | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.192 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.191 | ||
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.187 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.187 | ||
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.187 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.186 | ||
| RPN1 | ribophorin I | 0.186 | ||
| TRIM32 | tripartite motif containing 32 | 0.185 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.185 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.184 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.183 | ||
| CLOCK | clock homolog (mouse) | 0.183 | Mouse | |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.181 | Mouse | |
| UBXN6 | UBX domain protein 6 | 0.181 | ||
| SIRT2 | sirtuin 2 | 0.179 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.178 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.177 | ||
| RNF8 | ring finger protein 8 | 0.177 | ||
| ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.176 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.176 | Human Mouse Fly | |
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.176 | ||
| C11orf58 | chromosome 11 open reading frame 58 | 0.175 | ||
| AXIN2 | axin 2 | 0.175 | ||
| WDR26 | WD repeat domain 26 | 0.173 | ||
| ZYG11B | zyg-11 homolog B (C. elegans) | 0.173 | ||
| ANXA1 | annexin A1 | 0.173 | ||
| ANKRD13A | ankyrin repeat domain 13A | 0.171 | ||
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.170 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.169 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.169 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.167 | ||
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.167 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.167 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.166 | ||
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.166 | ||
| ZNF263 | zinc finger protein 263 | 0.166 | ||
| SRGN | serglycin | 0.166 | ||
| USP38 | ubiquitin specific peptidase 38 | 0.166 | Fly | |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.165 | ||
| GRN | granulin | 0.164 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.163 | ||
| UBXN2A | UBX domain protein 2A | 0.162 | ||
| JUN | jun proto-oncogene | 0.159 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.159 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.158 | ||
| BAX | BCL2-associated X protein | 0.158 | ||
| SPOP | speckle-type POZ protein | 0.157 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.157 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.157 | ||
| NCK2 | NCK adaptor protein 2 | 0.157 | ||
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.155 | Yeast | |
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.155 | ||
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.155 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.155 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.155 | Human | |
| MYO6 | myosin VI | 0.154 | ||
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.154 | ||
| ANXA7 | annexin A7 | 0.154 | ||
| ZNF148 | zinc finger protein 148 | 0.153 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.153 | ||
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.153 | ||
| RNF130 | ring finger protein 130 | 0.152 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.151 | ||
| S100A4 | S100 calcium binding protein A4 | 0.151 | ||
| TPBG | trophoblast glycoprotein | 0.151 | ||
| SIAH2 | seven in absentia homolog 2 (Drosophila) | 0.150 | Human | |
| SCAF11 | SR-related CTD-associated factor 11 | 0.150 | ||
| PSEN1 | presenilin 1 | 0.149 | Mouse | |
| RING1 | ring finger protein 1 | 0.148 | ||
| HDAC11 | histone deacetylase 11 | 0.147 | ||
| PTEN | phosphatase and tensin homolog | 0.147 | ||
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.147 | Human | |
| COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.146 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.146 | ||
| CDK17 | cyclin-dependent kinase 17 | 0.145 | ||
| LNX1 | ligand of numb-protein X 1 | 0.145 | Mouse | |
| CCNB2 | cyclin B2 | 0.145 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.145 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.144 | ||
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.144 | ||
| RNF31 | ring finger protein 31 | 0.143 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.143 | Human | |
| CBX5 | chromobox homolog 5 | 0.143 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.143 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.142 | Human | |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.140 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.140 | ||
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.139 | ||
| DNM2 | dynamin 2 | 0.138 | ||
| VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | 0.138 | ||
| TRIM41 | tripartite motif containing 41 | 0.138 | Human | |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.138 | ||
| BABAM1 | BRISC and BRCA1 A complex member 1 | 0.137 | ||
| HDAC4 | histone deacetylase 4 | 0.137 | ||
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.136 | ||
| NUDCD3 | NudC domain containing 3 | 0.136 | ||
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.136 | ||
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.136 | ||
| RANBP2 | RAN binding protein 2 | 0.136 | ||
| CTSA | cathepsin A | 0.135 | ||
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.135 | ||
| TPP1 | tripeptidyl peptidase I | 0.135 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.135 | Human | |
| VPRBP | Vpr (HIV-1) binding protein | 0.134 | ||
| OXSR1 | oxidative-stress responsive 1 | 0.134 | ||
| MTDH | metadherin | 0.133 | ||
| EIF5 | eukaryotic translation initiation factor 5 | 0.132 | ||
| HTRA2 | HtrA serine peptidase 2 | 0.132 | ||
| CANX | calnexin | 0.131 | ||
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.131 | Human | |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 0.131 | ||
| MYH9 | myosin, heavy chain 9, non-muscle | 0.130 | ||
| CDYL | chromodomain protein, Y-like | 0.130 | ||
| DAPK1 | death-associated protein kinase 1 | 0.130 | ||
| RLIM | ring finger protein, LIM domain interacting | 0.129 | Mouse | |
| STIP1 | stress-induced-phosphoprotein 1 | 0.128 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.128 | ||
| DOCK7 | dedicator of cytokinesis 7 | 0.128 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.128 | ||
| BFAR | bifunctional apoptosis regulator | 0.127 | ||
| TERF2 | telomeric repeat binding factor 2 | 0.126 | Human | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.125 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.125 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.124 | ||
| TLK1 | tousled-like kinase 1 | 0.124 | Human | |
| HIST2H2AC | histone cluster 2, H2ac | 0.124 | ||
| ING4 | inhibitor of growth family, member 4 | 0.124 | ||
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.124 | ||
| CHMP4B | chromatin modifying protein 4B | 0.124 | ||
| LIN28B | lin-28 homolog B (C. elegans) | 0.123 | ||
| CACYBP | calcyclin binding protein | 0.123 | ||
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.123 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.123 | ||
| PCGF2 | polycomb group ring finger 2 | 0.123 | ||
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.122 | ||
| KIAA0232 | KIAA0232 | 0.122 | ||
| TMEM173 | transmembrane protein 173 | 0.122 | ||
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.122 | ||
| NPEPPS | aminopeptidase puromycin sensitive | 0.121 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.121 | Mouse | |
| BTBD10 | BTB (POZ) domain containing 10 | 0.121 | ||
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 0.121 | ||
| ATF5 | activating transcription factor 5 | 0.121 | ||
| PRNP | prion protein | 0.120 | ||
| SURF4 | surfeit 4 | 0.120 | ||
| FBXW5 | F-box and WD repeat domain containing 5 | 0.119 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.119 | ||
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.119 | ||
| SMAD9 | SMAD family member 9 | 0.119 | ||
| RNF185 | ring finger protein 185 | 0.119 | Human | |
| FBXO33 | F-box protein 33 | 0.118 | ||
| MYO1C | myosin IC | 0.118 | ||
| ATF3 | activating transcription factor 3 | 0.118 | ||
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.117 | ||
| RNF181 | ring finger protein 181 | 0.117 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.117 | ||
| GATAD2B | GATA zinc finger domain containing 2B | 0.117 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.116 | Human | |
| BRAP | BRCA1 associated protein | 0.116 | ||
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 0.114 | ||
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.113 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.113 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.113 | Human | |
| CCNE2 | cyclin E2 | 0.113 | Fly | |
| NEURL4 | neuralized homolog 4 (Drosophila) | 0.113 | ||
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.112 | ||
| FBXO3 | F-box protein 3 | 0.112 | ||
| SLC38A2 | solute carrier family 38, member 2 | 0.112 | ||
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.112 | ||
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.111 | ||
| FOXM1 | forkhead box M1 | 0.111 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.111 | ||
| IER3 | immediate early response 3 | 0.111 | ||
| MAPT | microtubule-associated protein tau | 0.110 | ||
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.110 | ||
| UBE2K | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | 0.110 | Yeast Mouse | |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.110 | ||
| FBXO4 | F-box protein 4 | 0.109 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.109 | ||
| RPN2 | ribophorin II | 0.109 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.109 | Mouse | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.109 | ||
| COIL | coilin | 0.108 | ||
| INO80 | INO80 homolog (S. cerevisiae) | 0.108 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.108 | ||
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.108 | ||
| CUL4B | cullin 4B | 0.107 | ||
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.107 | ||
| DHPS | deoxyhypusine synthase | 0.106 | ||
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.106 | Yeast | |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.106 | ||
| ZNF207 | zinc finger protein 207 | 0.106 | ||
| BTBD1 | BTB (POZ) domain containing 1 | 0.105 | ||
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.105 | ||
| PRMT6 | protein arginine methyltransferase 6 | 0.104 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.104 | ||
| MBNL2 | muscleblind-like 2 (Drosophila) | 0.103 | ||
| FEN1 | flap structure-specific endonuclease 1 | 0.103 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.103 | ||
| ATM | ataxia telangiectasia mutated | 0.103 | ||
| LAP3 | leucine aminopeptidase 3 | 0.103 | ||
| ANAPC10 | anaphase promoting complex subunit 10 | 0.102 | Yeast | |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.102 | ||
| RDBP | RD RNA binding protein | 0.102 | ||
| TBCB | tubulin folding cofactor B | 0.102 | ||
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.102 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.102 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.101 | ||
| KLHL8 | kelch-like 8 (Drosophila) | 0.101 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.101 | ||
| CDC37L1 | cell division cycle 37 homolog (S. cerevisiae)-like 1 | 0.100 | ||
| RNF41 | ring finger protein 41 | 0.100 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.100 | Human | |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.100 | ||
| MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.099 | ||
| DERL2 | Der1-like domain family, member 2 | 0.099 | ||
| ING2 | inhibitor of growth family, member 2 | 0.099 | ||
| YAF2 | YY1 associated factor 2 | 0.099 | Fly | |
| IFI35 | interferon-induced protein 35 | 0.098 | ||
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.098 | ||
| FBXO30 | F-box protein 30 | 0.098 | ||
| ZNF746 | zinc finger protein 746 | 0.098 | ||
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.098 | ||
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.098 | Yeast | |
| TRIM63 | tripartite motif containing 63 | 0.098 | Human Mouse | |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.098 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.097 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.096 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.096 | Human | |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.096 | ||
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.096 | ||
| TOR1AIP2 | torsin A interacting protein 2 | 0.096 | ||
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 0.096 | ||
| SCARB2 | scavenger receptor class B, member 2 | 0.095 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.095 | ||
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.095 | ||
| DCTN4 | dynactin 4 (p62) | 0.095 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.094 | ||
| PRKCD | protein kinase C, delta | 0.094 | ||
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.094 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.094 | ||
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.094 | ||
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.094 | ||
| RDX | radixin | 0.094 | Fly | |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.094 | ||
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.094 | ||
| BIRC5 | baculoviral IAP repeat containing 5 | 0.093 | ||
| USP25 | ubiquitin specific peptidase 25 | 0.093 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.093 | ||
| KIAA1033 | KIAA1033 | 0.093 | ||
| GORAB | golgin, RAB6-interacting | 0.093 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.092 | Fly | |
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.092 | ||
| SON | SON DNA binding protein | 0.092 | ||
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.092 | ||
| HLA-B | major histocompatibility complex, class I, B | 0.092 | ||
| PDCD6 | programmed cell death 6 | 0.092 | ||
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.092 | ||
| RHOB | ras homolog gene family, member B | 0.092 | ||
| HELLS | helicase, lymphoid-specific | 0.092 | ||
| HEXA | hexosaminidase A (alpha polypeptide) | 0.092 | ||
| EXOC5 | exocyst complex component 5 | 0.092 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.091 | ||
| PCBP1 | poly(rC) binding protein 1 | 0.091 | Human | |
| TRIM33 | tripartite motif containing 33 | 0.090 | ||
| TRAPPC8 | trafficking protein particle complex 8 | 0.090 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.090 | ||
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.090 | Mouse | |
| NRD1 | nardilysin (N-arginine dibasic convertase) | 0.090 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.090 | ||
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.089 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.089 | ||
| RNF166 | ring finger protein 166 | 0.089 | ||
| MAP1A | microtubule-associated protein 1A | 0.089 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.089 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.089 | ||
| PCM1 | pericentriolar material 1 | 0.089 | ||
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.088 | ||
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.088 | ||
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.088 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.088 | ||
| GDI1 | GDP dissociation inhibitor 1 | 0.088 | ||
| BIRC8 | baculoviral IAP repeat containing 8 | 0.088 | Human | |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.088 | ||
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.087 | ||
| TUBB2C | tubulin, beta 2C | 0.087 | ||
| SKIL | SKI-like oncogene | 0.087 | ||
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.087 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.087 | Fly | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.087 | ||
| RFWD3 | ring finger and WD repeat domain 3 | 0.087 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.086 | ||
| ZMYND19 | zinc finger, MYND-type containing 19 | 0.086 | ||
| SFN | stratifin | 0.086 | ||
| TH1L | TH1-like (Drosophila) | 0.086 | ||
| SDF4 | stromal cell derived factor 4 | 0.086 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.086 | ||
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.086 | ||
| FUNDC2 | FUN14 domain containing 2 | 0.086 | ||
| PCBP2 | poly(rC) binding protein 2 | 0.085 | ||
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.085 | ||
| KLHL2 | kelch-like 2, Mayven (Drosophila) | 0.085 | Human | |
| ZWINT | ZW10 interactor | 0.085 | ||
| TMEM33 | transmembrane protein 33 | 0.085 | ||
| ANKRD52 | ankyrin repeat domain 52 | 0.085 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.084 | ||
| RNF13 | ring finger protein 13 | 0.084 | ||
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.084 | ||
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.084 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.084 | ||
| SOCS6 | suppressor of cytokine signaling 6 | 0.084 | ||
| VCL | vinculin | 0.084 | ||
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.083 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.083 | ||
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.083 | ||
| ING1 | inhibitor of growth family, member 1 | 0.083 | ||
| KALRN | kalirin, RhoGEF kinase | 0.083 | ||
| FAM175B | family with sequence similarity 175, member B | 0.083 | ||
| PFN2 | profilin 2 | 0.083 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.083 | ||
| SP100 | SP100 nuclear antigen | 0.082 | ||
| KLHL13 | kelch-like 13 (Drosophila) | 0.082 | Human | |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.082 | ||
| TLK2 | tousled-like kinase 2 | 0.082 | ||
| RUVBL2 | RuvB-like 2 (E. coli) | 0.082 | ||
| MEX3B | mex-3 homolog B (C. elegans) | 0.081 | ||
| RYR2 | ryanodine receptor 2 (cardiac) | 0.081 | ||
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.081 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.081 | ||
| TUBB | tubulin, beta | 0.081 | ||
| KLHDC5 | kelch domain containing 5 | 0.081 | ||
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 0.081 | ||
| APIP | APAF1 interacting protein | 0.081 | ||
| PHF21A | PHD finger protein 21A | 0.080 | ||
| HIST1H4A | histone cluster 1, H4a | 0.080 | ||
| DNM1L | dynamin 1-like | 0.080 | ||
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.080 | ||
| RPL11 | ribosomal protein L11 | 0.080 | ||
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 0.080 | ||
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.080 | ||
| HSF1 | heat shock transcription factor 1 | 0.080 | ||
| AP1M1 | adaptor-related protein complex 1, mu 1 subunit | 0.080 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.080 | Human | |
| SPAG9 | sperm associated antigen 9 | 0.079 | ||
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.079 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.079 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.079 | ||
| CCND3 | cyclin D3 | 0.079 | ||
| KLHL20 | kelch-like 20 (Drosophila) | 0.079 | ||
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.079 | ||
| GATAD2A | GATA zinc finger domain containing 2A | 0.079 | ||
| RIOK3 | RIO kinase 3 (yeast) | 0.078 | ||
| HECTD1 | HECT domain containing 1 | 0.078 | Human | |
| HDAC3 | histone deacetylase 3 | 0.078 | ||
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.078 | ||
| AHR | aryl hydrocarbon receptor | 0.077 | ||
| SENP1 | SUMO1/sentrin specific peptidase 1 | 0.077 | Mouse | |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.077 | ||
| FBXO25 | F-box protein 25 | 0.077 | ||
| MBD4 | methyl-CpG binding domain protein 4 | 0.077 | ||
| KSR1 | kinase suppressor of ras 1 | 0.077 | Human | |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.077 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.077 | ||
| THAP11 | THAP domain containing 11 | 0.076 | ||
| MID1 | midline 1 (Opitz/BBB syndrome) | 0.076 | ||
| GNAS | GNAS complex locus | 0.076 | ||
| SPIN1 | spindlin 1 | 0.076 | ||
| UBE4A | ubiquitination factor E4A (UFD2 homolog, yeast) | 0.076 | Human | |
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.076 | ||
| SNX33 | sorting nexin 33 | 0.076 | ||
| ANKRD13C | ankyrin repeat domain 13C | 0.076 | ||
| FLNB | filamin B, beta | 0.075 | ||
| MAP4 | microtubule-associated protein 4 | 0.075 | ||
| MAP1S | microtubule-associated protein 1S | 0.075 | ||
| PHF20L1 | PHD finger protein 20-like 1 | 0.075 | ||
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.075 | ||
| TCP1 | t-complex 1 | 0.075 | ||
| FNTA | farnesyltransferase, CAAX box, alpha | 0.075 | ||
| TBP | TATA box binding protein | 0.075 | ||
| PRRC1 | proline-rich coiled-coil 1 | 0.075 |